Works Published in 2015

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Displaying works 161 - 180 of 264 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives

TETRAHEDRON LETTERS, 56(23), 3406–3409.

By: M. Richardson*, R. Furlani n, B. Podell*, D. Ackart*, J. Haugen*, R. Melander n, C. Melander, R. Basaraba*

author keywords: Advanced glycation end-products (AGES); Bis-2-aminoimidazole; Aminoguanidine; Diabetes
TL;DR: The screening of a series of 2-aminoimidazloles for anti-AGE activity is reported, and the identification of a bis-2-aminosidazole lead compound that possesses superior AGE inhibition and breaking activity compared to the known AGE inhibitor aminoguanidine is identified. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Elevated cholesteryl ester transfer protein (CETP) activity, a major determinant of the atherogenic dyslipidemia, and atherosclerotic cardiovascular disease in South Asians

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 22(4), 468–477.

author keywords: Cholesteryl ester transfer protein (CETP); HDL; LDL; atherogenic dyslipoproteinemia; atherosclerotic cardiovascular diseases; South Asians
MeSH headings : Adult; Aged; Asia / ethnology; Asian People; Atherosclerosis / blood; Atherosclerosis / diagnosis; Atherosclerosis / ethnology; Biomarkers / blood; Canada / epidemiology; Cholesterol Ester Transfer Proteins / blood; Cholesterol, HDL / blood; Cholesterol, LDL / blood; Cross-Sectional Studies; Dyslipidemias / blood; Dyslipidemias / diagnosis; Dyslipidemias / ethnology; Europe / ethnology; Female; Health Status Disparities; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index; Triglycerides / blood; Up-Regulation; White People
TL;DR: Novel associations are identified between elevated CETP activity and the triad of quantitative and qualitative lipoprotein abnormalities in the atherogenic dyslipidemia in South Asia, a major contributor of increased atherosclerotic cardiovascular diseases in South Asians. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Elaboration of an unexplored substitution site in synthetic bacteriochlorins

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 19(7), 887–902.

By: N. Zhang n, K. Reddy n, J. Jiang n, M. Taniguchi n, R. Sommer n & J. Lindsey n

Contributors: N. Zhang n, K. Reddy n, J. Jiang n, M. Taniguchi n, R. Sommer n & J. Lindsey n

author keywords: hydroporphyrin; dioxepine; chlorophyllone; bacteriochlorophyllone; auxochrome; artificial photosynthesis
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

Efficient Visible to Near-UV Photochemical Upconversion Sensitized by a Long Lifetime Cu(I) MLCT Complex

INORGANIC CHEMISTRY, 54(12), 6035–6042.

By: C. McCusker n & F. Castellano n

Contributors: C. McCusker n & F. Castellano n

TL;DR: Photochemical upconversion quantum efficiencies were evaluated using a relative actinometric method as both a function of incident light power density as well as anthryl acceptor/annihilator concentration and the combination of 1 with DMA was shown to be quite robust, showing no obvious signs of decomposition during 12 h of continuous 488 nm photolysis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Diblock Copolymer Micelles and Supported Films with Noncovalently Incorporated Chromophores: A Modular Platform for Efficient Energy Transfer

NANO LETTERS, 15(4), 2422–2428.

author keywords: Amphiphilic diblock copolymers; artificial light harvesting; Forster resonance energy transfer
TL;DR: Generation of modular, artificial light-harvesting assemblies where an amphiphilic diblock copolymer, poly(ethylene oxide)-block-poly(butadiene), serves as the framework for noncovalent organization of BODIPY-based energy donor and bacteriochlorin- based energy acceptor chromophores are reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Development of a tandem affinity phosphoproteomic method with motif selectivity and its application in analysis of signal transduction networks

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 988, 166–174.

By: L. Herring n, K. Grant*, K. Blackburn n, J. Haugh n & M. Goshe n

author keywords: Phosphopeptide enrichment; Liquid chromatography; Mass spectrometry; Motif analysis; Pathway analysis
MeSH headings : Amino Acid Sequence; Chromatography, Liquid / methods; Molecular Sequence Data; Phosphopeptides / analysis; Phosphopeptides / chemistry; Proteomics / methods; Signal Transduction / physiology; Tandem Mass Spectrometry / methods
TL;DR: A multi-dimensional method incorporating electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) with tandem IMAC/TiO2 enrichment for subsequent phosphopeptide identification by LC/MS/MS and biological functions that were over-represented at each PDGF stimulation time point illustrate the feasibility of this approach in quantitative phosphoproteomic studies. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Dendritic near-IR absorbing zinc phthalocyanines for antimicrobial photodynamic therapy

Tetrahedron Letters, 56(23), 3541–3545.

By: D. Muli*, B. Carpenter n, M. Mayukh*, R. Ghiladi n & D. McGrath*

Contributors: D. Muli*, B. Carpenter n, M. Mayukh*, R. Ghiladi n & D. McGrath*

author keywords: Non-aggregated; Water soluble; Click chemistry; Singlet oxygen; Methylene blue
TL;DR: Both ZnPcs showed negligible dark toxicity on bacteria and yeast with 10 μM 1a and 1b, and aggregation studies indicate that non-peripherally substituted 1b is significantly less aggregated in aqueous media than peripherally substitution 1a . (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Definitive Screening Design Optimization of Mass Spectrometry Parameters for Sensitive Comparison of Filter and Solid Phase Extraction Purified, INLIGHT Plasma N-Glycans

ANALYTICAL CHEMISTRY, 87(14), 7305–7312.

By: E. Hecht n, J. McCord n & D. Muddiman n

MeSH headings : Animals; Chickens; Equipment Design; Mass Spectrometry / instrumentation; Polysaccharides / blood; Polysaccharides / isolation & purification; Solid Phase Extraction / instrumentation
TL;DR: High-throughput, quantitative processing of N-linked glycans would facilitate large-scale studies correlating the glycome with disease and open the field to basic and applied researchers by coupling filter-aided-N-glycan separation to the individuality normalization when labeling with glycan hydrazide tags (INLIGHT) for analysis of plasma. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 personal communication

Curation of chemogenomics data

Fourches, D., Muratov, E., & Tropsha, A. (2015, August).

MeSH headings : Drug Design; Humans; Information Dissemination; Pharmacogenetics / standards; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; Software
TL;DR: A general chemical and biological data curation workflow that relies on existing cheminformatics approaches to flag, and in some cases correct, possibly erroneous entries in large chemogenomics datasets is proposed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Bupropion Increases Selection of High Effort Activity in Rats Tested on a Progressive Ratio/Chow Feeding Choice Procedure: Implications for Treatment of Effort-Related Motivational Symptoms

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 18(2).

By: P. Randall n, C. Lee n, S. Podurgiel n, E. Hart n, S. Yohn n, M. Jones n, M. Rowland n, L. Lopez-Cruz n, M. Correa n, J. Salamone n

author keywords: dopamine; nucleus accumbens; depression; fatigue; animal models
MeSH headings : Animals; Bupropion / pharmacology; Choice Behavior / drug effects; Choice Behavior / physiology; Chromatography, High Pressure Liquid; Dopamine / metabolism; Dopamine Uptake Inhibitors / pharmacology; Dopamine and cAMP-Regulated Phosphoprotein 32 / metabolism; Dose-Response Relationship, Drug; Food; Immunohistochemistry; Male; Microdialysis; Motivation / drug effects; Motivation / physiology; Nucleus Accumbens / drug effects; Nucleus Accumbens / physiology; Phosphorylation / drug effects; Psychotropic Drugs / pharmacology; Rats, Sprague-Dawley; Reinforcement Schedule
TL;DR: The ability of bupropion to increase exertion of effort in instrumental behavior may have implications for the pathophysiology and treatment of effort-related motivational symptoms in humans. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Antiviral, Antifungal and Antibacterial Activities of a BODIPY-Based Photosensitizer

Molecules, 20(6), 10604–10621.

By: B. Carpenter n, X. Situ n, F. Scholle n, J. Bartelmess n, W. Weare n & R. Ghiladi n

Contributors: B. Carpenter n, X. Situ n, F. Scholle n, J. Bartelmess n, W. Weare n & R. Ghiladi n

author keywords: photodynamic therapy; singlet oxygen; antibacterial; antiviral; antifungal; photobiocidal
MeSH headings : Anti-Bacterial Agents; Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacology; Antifungal Agents; Antiviral Agents; Boron Compounds / chemistry; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Photosensitizing Agents / chemistry; Photosensitizing Agents / pharmacology
TL;DR: The results demonstrate that DIMPy-BODIPY exhibits antiviral, antibacterial and antifungal photodynamic inactivation at nanomolar concentrations and short illumination times. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

A concise synthesis of the Lycopodium alkaloid cermizine D

TETRAHEDRON LETTERS, 56(23), 3683–3685.

By: M. Enamorado n, C. Connelly n, A. Deiters n & D. Comins n

author keywords: Alkaloid synthesis; Lycopodium alkaloids; Nitrogen heterocycles; 1-Acylpyridinium salts; Asymmetric synthesis
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Unexpected Precursor Effects to the Structural Phase Transition in EuTiO3

ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 641(2), 180–183.

By: A. Bussmann-Holder*, J. Koehler & M. Whangbo n

author keywords: Multiferroics; Magnetic properties; Dielectrics
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Transition Zone Theory of Crystal Growth and Viscosity

Chemistry of Materials, 27(9), 3526–3532.

By: F. Hou n, J. Martin n, E. Dill n, J. Folmer n & A. Josey n

Contributors: F. Hou n, J. Martin n, E. Dill n, J. Folmer n & A. Josey n

Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Transient Absorption Dynamics of Sterically Congested Cu(I) MLCT Excited States

JOURNAL OF PHYSICAL CHEMISTRY A, 119(13), 3181–3193.

Contributors: S. Garakyaraghi n, E. Danilov n, C. McCusker n & F. Castellano n

TL;DR: The molecule with the most inhibited potential for distortion, [Cu(dsbtmp)2](+), possessed the fastest ultrafast dynamics as well as the longest excited state lifetimes in both solvents, illustrating that strongly impeded structural distortion in Cu(I) MLCT excited state enables more rapid surface crossings in the initial deactivation dynamics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Tolerance Factor and Cation-Anion Orbital Interactions Differentiating the Polar and Antiferrodistortive Structures of Perovskite Oxides ABO(3)

ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 641(6), 1043–1052.

author keywords: Perovskite; Polar structure; Antiferrodistortive structure; Jahn-Teller instability; Cation-anion interaction; Tolerance factor
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Synthesis, Characterization, and Photophysical Studies of an Iron(III) Catecholate-Nitronylnitroxide Spin-Crossover Complex

INORGANIC CHEMISTRY, 54(9), 4466–4474.

By: C. Tichnell n, D. Shultz n, C. Popescu*, I. Sokirniy* & P. Boyle n

TL;DR: Although the effects of the NN radical are manifest in neither the spin-crossover nor the photophysics, the results lay the groundwork for future studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Synthesis and X-ray analysis of a perfluoroalkyl-substituted azobenzene dye

DYES AND PIGMENTS, 120, 245–250.

author keywords: Perfluoroalkylazo dye; Aminoazobenzene dye; X-ray diffraction; Crystal structure; Torsion angle; Surface energy
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Synthesis and Reactivity of Oxorhenium(V) Methyl, Benzyl, and Phenyl Complexes with CO: Implications for a Unique Mechanism for Migratory Insertion

ORGANOMETALLICS, 34(13), 3152–3158.

By: L. Robbins n, C. Lilly n, J. Smeltz n, P. Boyle n & E. Ison n

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Photophysical Properties and Electronic Structure of Chlorin-Imides: Bridging the Gap between Chlorins and Bacteriochlorins

JOURNAL OF PHYSICAL CHEMISTRY B, 119(24), 7503–7515.

By: K. Faries*, J. Diers*, J. Springer*, E. Yang*, M. Ptaszek n, D. Lahaye n, M. Krayer n, M. Taniguchi n ...

Contributors: K. Faries*, J. Diers*, J. Springer*, E. Yang*, M. Ptaszek n, D. Lahaye n, M. Krayer n, M. Taniguchi n ...

MeSH headings : Electrons; Fluorescence; Imides / chemistry; Molecular Structure; Photochemical Processes; Porphyrins / chemistry; Quantum Theory
TL;DR: The photophysical properties of a set of six chlorin-imides and nine synthetic chlorin analogues that extend the absorption deeper into these key spectral regions of the solar spectrum and help bridge the gap between typical chlorins and bacteriochlorins are reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

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