Works Published in 2022
Displaying works 561 - 580 of 652 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2022 article
Distributed Cox proportional hazards regression using summary-level information
Li, D., Lu, W., Shu, D., Toh, S., & Wang, R. (2022, February 23). BIOSTATISTICS.
author keywords: Distributed Cox PH regression; Meta-analysis; Multi-site study; Summary-level information
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 7, 2022
2022 journal article
Optimized C-Trap Timing of an Orbitrap 240 Mass Spectrometer for High-Throughput Screening and Native MS by IR-MALDESI
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 33(2), 328–334.
author keywords: high-throughput screening; IR-MALDESI; Orbitrap mass spectrometer; C-trap
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 7, 2022
2022 journal article
Continuous flow microwave-assisted aqueous extraction of pomace phytoactives for production of protein-polyphenol particles and a protein-enriched ready-to-drink beverage
Future Foods.
doi.org (publisher)
Source: ORCID
Added: March 4, 2022
2022 journal article
Single-Cell-Based High-Throughput Ig and TCR Repertoire Sequencing Analysis in Rhesus Macaques
JOURNAL OF IMMUNOLOGY, 208(3), 762–771.
MeSH headings : Animals; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Immunoglobulins / genetics; Macaca mulatta; Receptors, Antigen, T-Cell, alpha-beta / genetics; Receptors, Antigen, T-Cell, gamma-delta / genetics; Single-Cell Analysis; T-Lymphocytes / immunology; Transcriptome / genetics; VDJ Exons / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 28, 2022
2022 article
Non-steroidal anti-inflammatory drugs in equine orthopaedics
Jacobs, C. C., Schnabel, L. V., McIlwraith, C. W., & Blikslager, A. T. (2022, February 10). EQUINE VETERINARY JOURNAL, Vol. 2.
author keywords: horse; non-steroidal anti-inflammatory drug; orthopaedics; osteoarthritis
TL;DR:
This review aims to summarise the current literature on the use of NSAIDs for equine orthopaedic disorders and examines new and future avenues for the management of inflammation in equine Orthopaedics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 28, 2022
2022 journal article
Investigating the Role of Artemin and Its Cognate Receptor, GFR alpha 3, in Osteoarthritis Pain
FRONTIERS IN NEUROSCIENCE, 16.
author keywords: pain; osteoarthritis (OA); artemin; GFR alpha 3; TRPV1; monoiodoacetate (MIA)
TL;DR:
The results provide a molecular basis of arthritis pain linked with artemin/GFRα3 signaling and indicate that further work is warranted to investigate the neuronal plasticity and the pathways that drive pain in OA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 28, 2022
2022 review
A review of epidemiological models of Clostridioides difficile transmission and control (2009e2021)
[Review of ]. ANAEROBE, 74.
author keywords: Clostridioides difficile; Transmission; Mathematical model; Bibliometric analysis
MeSH headings : Clostridioides; Clostridioides difficile; Clostridium Infections / prevention & control; Cross Infection / epidemiology; Epidemiological Models; Humans
TL;DR:
A systematic search and a bibliometric analysis of mathematical and computational models for Clostridioides difficile transmission identified 33 publications from 2009 to 2021 that underscored the importance of asymptomatic colonized patients in maintaining transmission in health-care settings.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 23, 2022
2022 article
Modelling and assessing additional transmission routes for porcine reproductive and respiratory syndrome virus: Vehicle movements and feed ingredients
Galvis, J. A., Corzo, C. A., & Machado, G. (2022, March 3). TRANSBOUNDARY AND EMERGING DISEASES, Vol. 3.
author keywords: animal by-product; contact networks; PRRSV transmission; swine disease dynamics; swine disease transmission; truck
MeSH headings : Animal Husbandry / methods; Animals; Biological Products; Female; Minerals; Porcine Reproductive and Respiratory Syndrome / epidemiology; Porcine respiratory and reproductive syndrome virus; Swine; Swine Diseases
TL;DR:
A mathematical model tailored to fit nine modes of between-farm transmission of porcine reproductive and respiratory syndrome virus (PRRSV) demonstrated the contribution of multiple routes of PRRSV dissemination, which has not been deeply explored before and provides strong evidence to support the need for cautious, measured PR RSV control strategies for transportation vehicles and further research for feed by-products modeling.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 22, 2022
2022 journal article
Loading during Midstance of Gait Is Associated with Magnetic Resonance Imaging of Cartilage Composition Following Anterior Cruciate Ligament Reconstruction
CARTILAGE, 13(1).
author keywords: biomechanics; vertical ground reaction force; posttraumatic osteoarthritis; T1 rho; ACL
MeSH headings : Adolescent; Adult; Anterior Cruciate Ligament Reconstruction / methods; Cartilage, Articular / pathology; Female; Gait; Humans; Knee Joint / diagnostic imaging; Knee Joint / surgery; Magnetic Resonance Imaging / methods; Male; Young Adult
TL;DR:
Biomechanical gait profiles that include greater vGRF during midstance are associated with MRI estimates of lesser proteoglycan density in the MFC, suggesting inability to unload the ACLR limb during midstances may be linked to joint tissue changes associated with PTOA development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: February 21, 2022
2022 journal article
Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(1).
author keywords: C-C coupling; cyclization; oxygenase; natural product; reaction mechanism
MeSH headings : Berberidaceae / enzymology; Drugs, Chinese Herbal / chemistry; Ligases / chemistry; Oxidation-Reduction; Plant Proteins / chemistry; Podophyllotoxin / analogs & derivatives; Podophyllotoxin / chemistry
TL;DR:
This study reports two structures of DPS in complex with 2OG and (±)-yatein, in vitro analysis of enzymatic reactivity with substrate analogs, and model reactions addressing DPS’s catalytic mechanism, and suggests what types of substrate modification are likely tolerable in DPS-catalyzed production of deoxypodophyllotoxin analogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 21, 2022
2022 journal article
Modified Histone Peptides Linked to Magnetic Beads Reduce Binding Specificity
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(3).
author keywords: yeast surface display; histone post-translational modifications; affinity reagents; protein engineering; chromodomain; binder; reader; antibody; epigenome engineering; synthetic biology
MeSH headings : HEK293 Cells; Histone Code; Histones / metabolism; Humans; Jurkat Cells; K562 Cells; Protein Array Analysis; Protein Binding; Protein Engineering; Protein Processing, Post-Translational; Saccharomyces cerevisiae
TL;DR:
Specific experimental conditions that affect binding specificities of post-translationally modified histones in classic protein engineering platforms are described and likely explain the relative difficulty with histone targets in these platforms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 21, 2022
2022 journal article
Induction of the Viable-but-Nonculturable State in Salmonella Contaminating Dried Fruit
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 88(2).
author keywords: dried fruit; survival; low-moisture foods; Salmonella; confocal microscopy; viable but nonculturable
MeSH headings : Colony Count, Microbial; Food Microbiology; Food, Preserved / microbiology; Fruit / microbiology; Humans; Microbial Viability; Salmonella / physiology; Temperature
TL;DR:
Findings from this study suggest that unique stressors on dried fruit can induce the VBNC state in Salmonella, thus rendering it undetectable with culture-based methods even though the bacteria remain viable.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 21, 2022
2022 journal article
Warm and arid regions of the world are hotspots of superorganism complexity
author keywords: Formicidae; ant castes; organismic complexity; social evolution; social organization
MeSH headings : Animals; Ants / genetics; Desert Climate; Neurons; Phenotype
TL;DR:
It is shown that arid regions of the world are the hotspots of superorganism complexity, and the possible adaptive advantages that worker polymorphism provides in arid environments are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 21, 2022
2022 review
The evolution of sour taste
author keywords: sour; evolution; taste; acidity; fermentation
MeSH headings : Animals; Humans; Phylogeny; Taste
TL;DR:
Why sour taste evolved, why it might have persisted as vertebrates made the transition to land and what factors might have favoured the preference for sour-tasting, acidic foods, particularly in hominins, such as humans are considered.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 21, 2022
2022 journal article
Cellular Processes in Human Ovarian Follicles Are Regulated by Expression Profile of New Gene Markers-Clinical Approach
JOURNAL OF CLINICAL MEDICINE, 11(1).
author keywords: cumulus cells; granulosa cells; human; gene expression; microarray; epithelialization
TL;DR:
Detailed analysis of gene expression in these two cell populations at different time intervals confirms their ovarian surface epithelial origin, and some gene expression profiles appear to have tumorigenic properties, suggesting that granulosa cells may play a role in cancerogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 14, 2022
2022 article
Turning CRISPR on with antibiotics
Barrangou, R., & Marraffini, L. A. (2022, January 12). CELL HOST & MICROBE, Vol. 30, pp. 12–14.
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacteria / genetics; Base Sequence; CRISPR-Cas Systems; Viruses
TL;DR:
Bacteriostatic antibiotics prompt CRISPR acquisition events, illustrating how environmental conditions affect complex dynamics between host and virus and the corresponding biological and genetic arms race.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 14, 2022
2022 article
Cyclin-dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle
Kim, S. H., Rodriguez, L. R. L., Macias, E., & Rodriguez-Puebla, M. L. (2022, February 3). CELL BIOLOGY INTERNATIONAL.
author keywords: cell-cycle; epidermis; keratinocytes; skin; stem
MeSH headings : Animals; Cyclin-Dependent Kinase 4 / metabolism; Hair Follicle / metabolism; Keratinocytes; Mice; Stem Cells
TL;DR:
It is reported that stem cells located in the bulge region of the HF (BuSCs) express high levels of cyclin‐dependent kinase 4 (CDK4) through the quiescent phase of the hair cycle, and deregulation of CDK4 protein levels contributes to distorting the self‐renewal/proliferation balance and, in turn, altering the number of BuSCs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 14, 2022
2022 journal article
Illumination angle correction during image acquisition in light-sheet fluorescence microscopy using deep learning
BIOMEDICAL OPTICS EXPRESS, 13(2), 888–901.
TL;DR:
This study provides a framework that can correct the angle of the light-sheet and improve the overall image quality in high-resolution LSFM 3D image acquisition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 14, 2022
2022 article
Pathology in Practice
Rasche, B. L., Parker, M., Lewbart, G. A., Petritz, O., & Watanabe, T. T. N. (2022, February 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 260, pp. 305–307.
MeSH headings : Animal Diseases / diagnosis; Animals
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 14, 2022
2022 journal article
Coupling high-throughput mapping with proteomics analysis delineates cis-regulatory elements at high resolution
NUCLEIC ACIDS RESEARCH, 50(1).
MeSH headings : Chromosome Mapping / methods; Gene Expression Regulation; Genome, Human; High-Throughput Nucleotide Sequencing / methods; Humans; Regulatory Sequences, Nucleic Acid
TL;DR:
The utility of Reel-seq and FREP-MS analyses for the systematic identification of cis-REs at high resolution over a large region of the human genome in a systematic and continuous manner is confirmed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 14, 2022
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