Works Published in 2020
Displaying works 101 - 114 of 114 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
An importin-beta-like protein mediates lignin-modification-induced dwarfism in Arabidopsis
PLANT JOURNAL, 102(6), 1281–1293.
author keywords: Arabidopsis thaliana; importin; lignin; MYB4; plant growth; ref8; suppressor mutant
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Adaptor Proteins, Signal Transducing / physiology; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / metabolism; Arabidopsis Proteins / physiology; Cell Division; Gene Expression Regulation, Plant; Lignin / metabolism; Repressor Proteins / metabolism; Repressor Proteins / physiology; Transcription Factors / metabolism; Transcription Factors / physiology; beta Karyopherins / metabolism
TL;DR:
It is shown that defects in both cell division and cell expansion underlie the dwarfism of an Arabidopsis lignin mutant ref8, and the identification of a GIR1 gene from a suppressor screen is reported, suggesting that the growth rescue effect of gir1 is likely due to compromised MYB4 transport and function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: March 10, 2020
2020 journal article
Spicing up gastrointestinal health with dietary essential oils
Phytochemistry Reviews, 19(2), 243–263.
Contributors: M. Tanveer n, C. Wagner n, M. Haq *, N. Ribeiro n, T. Rathinasabapathy n , M. Butt *, A. Shehzad *, S. Komarnytsky n
author keywords: Essential oils; Indigestion; Gastroesophageal reflux; Dyspepsia; Gastritis
TL;DR:
8 botanical interventions including fennel, rosemary, ginger, peppermint, and dill were identified that prevented gastric ulcer formation, reduced production of gastric acids, or promoted upper gastrointestinal healing in preclinical or early phase human studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: March 5, 2020
2020 journal article
Serum endotoxin, gut permeability and skeletal muscle metabolic adaptations following a short term high fat diet in humans
METABOLISM-CLINICAL AND EXPERIMENTAL, 103.
author keywords: Skeletal muscle; Substrate oxidation; Metabolic flexibility; High fat diet; Metabolic adaptation
MeSH headings : Adaptation, Physiological / physiology; Adult; Diet, High-Fat; Dietary Fats / pharmacology; Endotoxins / blood; Energy Metabolism / drug effects; Humans; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Intestines / drug effects; Intestines / pathology; Lipid Metabolism / drug effects; Male; Muscle, Skeletal / drug effects; Muscle, Skeletal / metabolism; Muscle, Skeletal / pathology; Permeability; Young Adult
TL;DR:
It is demonstrated that in healthy young men, consuming an isocaloric HFD for 5 days increases fasting endotoxin, independent of changes in gut permeability, and these changes in endotoxin are accompanied by a broad effect on skeletal muscle substrate metabolism including increases in postprandial fat oxidation.
(via Semantic Scholar)
www.metabolismjournal.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 27, 2020
2020 journal article
Cucurbitaceae Germplasm Resistance to Verticillium Wilt and Grafting Compatibility with Watermelon
HORTSCIENCE, 55(2), 141–148.
author keywords: crop quality; disease resistance; germplasm accessions; grafting success; soilborne disease; yield
TL;DR:
Six verticillium wilt-tolerant accessions that were compatible with watermelon could potentially be used as rootstocks or as sources of genetic resistance in rootstock breeding programs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: February 27, 2020
2020 journal article
Flavone Hispidulin Stimulates Glucagon-Like Peptide-1 Secretion and Ameliorates Hyperglycemia in Streptozotocin-Induced Diabetic Mice
MOLECULAR NUTRITION & FOOD RESEARCH, 64(6).
author keywords: diabetes; glucagon-like peptide-1; hispidulin; insulin; mice
MeSH headings : Animals; Cell Line; Cell Survival / drug effects; Cyclic AMP / metabolism; Cyclic AMP-Dependent Protein Kinases / metabolism; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Eating / drug effects; Flavones / pharmacology; Glucagon-Like Peptide 1 / metabolism; Hyperglycemia / drug therapy; Hyperglycemia / metabolism; Hypoglycemic Agents / pharmacology; Insulin / metabolism; Insulin-Secreting Cells / drug effects; Insulin-Secreting Cells / metabolism; Male; Mice, Inbred C57BL
TL;DR:
Hispidulin significantly improved glycemic control in diabetic mice, concomitant with improved insulin release and β-cell survival, and suggest that hispidulin may be a novel dual-action anti-diabetic compound via stimulating GLP-1 secretion and suppressing hepatic glucose production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: February 17, 2020
2020 journal article
Improving natural product research translation: From source to clinical trial
FASEB JOURNAL, 34(1), 41–65.
author keywords: clinical predictive validity; dietary supplements; model systems; rigor and replicability; value of information
MeSH headings : Animals; Biological Products / pharmacology; Drug Evaluation, Preclinical; Ethnobotany; Humans; Translational Research, Biomedical / standards
TL;DR:
More effective bridging from NP research to CT was the goal of a September, 2018 transdisciplinary workshop, and participants emphasized that replicability and likelihood of successful translation depend on rigor in experimental design, interpretation, and reporting across the continuum of NP research.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: February 3, 2020
2020 journal article
Human Papillomavirus 16 E5 Inhibits Interferon Signaling and Supports Episomal Viral Maintenance
JOURNAL OF VIROLOGY, 94(2).
author keywords: E5; EGFR; STAT signaling; TGFBR2; innate immunity; interferon kappa; papillomavirus
MeSH headings : Cell Line; Genome, Viral; Genomic Instability; Human papillomavirus 16 / genetics; Human papillomavirus 16 / metabolism; Humans; Interferon Type I / genetics; Interferon Type I / metabolism; Keratinocytes / metabolism; Keratinocytes / pathology; Keratinocytes / virology; Oncogene Proteins, Viral / genetics; Oncogene Proteins, Viral / metabolism; Papillomavirus Infections / genetics; Papillomavirus Infections / metabolism; Papillomavirus Infections / pathology; Plasmids / genetics; Plasmids / metabolism; Signal Transduction
TL;DR:
A previously unknown function of the HPV16 E5 oncoprotein in the suppression of interferon (IFN) responses is discovered and it is found that the E5 protein is important for helping the virus avoid integration into the host genome, which is a frequent step along the pathway to cancer development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: January 21, 2020
2020 journal article
Gallic acid loaded poloxamer gel as new adjuvant strategy for melanoma: A preliminary study
COLLOIDS AND SURFACES B-BIOINTERFACES, 185.
author keywords: Biocompatible polymers; Polymer gels; In vitro diffusion; Polymer membranes; Gallic acid; Franz cell
MeSH headings : Adjuvants, Immunologic / pharmacology; Adjuvants, Immunologic / therapeutic use; Cell Line; Cell Movement / drug effects; Diffusion; Elasticity; Gallic Acid / pharmacology; Gallic Acid / therapeutic use; Gels / chemistry; Humans; Kinetics; Melanoma / drug therapy; Phase Transition; Poloxamer / chemistry; Rheology; Temperature; Viscosity; Wound Healing / drug effects
TL;DR:
Scratch wound healing and migration assays conducted on human keratinocytes and melanoma cells demonstrated the ability of gallic acid loaded gel to inhibit cellular migration, suggesting its potential as adjuvant strategy for melanoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 13, 2020
2020 journal article
Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation
REDOX BIOLOGY, 28.
author keywords: NLRP3; ASC; Inflammatory status; Cytokines; MeCP2
MeSH headings : Biomarkers; Cytokines / metabolism; Disease Susceptibility; Fibroblasts / metabolism; Fluorescent Antibody Technique; Humans; Inflammasomes / metabolism; Inflammation Mediators / metabolism; Interleukin-1beta / metabolism; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Protein Transport; Rett Syndrome / etiology; Rett Syndrome / metabolism
TL;DR:
It is suggested that RTT patients exhibited a challenged inflammasome machinery at cellular and systemic level, which may contribute to the subclinical inflammatory state feedback observed in this pathology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 30, 2019
2020 review
Mimicking cigarette smoke exposure to assess cutaneous toxicity
[Review of ]. TOXICOLOGY IN VITRO, 62.
author keywords: Cigarette smoke; Skin models; Inflammation; Oxidative stress; Psoriasis; Atopic dermatitis
MeSH headings : Animals; Humans; Skin / drug effects; Skin Diseases / chemically induced; Tobacco Products; Tobacco Smoke Pollution / adverse effects
TL;DR:
An update is provided on the skin models currently available to study cigarette smoke exposure and the known pathways involved in cutaneous toxicity and the inflammatory skin pathologies potentially induced and/or exacerbated by cigarette smoke Exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 30, 2019
2020 journal article
Phenolic compounds are less degraded in presence of starch than in presence of proteins through processing in model porridges
FOOD CHEMISTRY, 309.
author keywords: Starch; Porridge; Processing; In vitro digestion; Gallic acid; Catechin; Epigallocatechin gallate; V-complex
MeSH headings : Catechin / analogs & derivatives; Catechin / chemistry; Catechin / metabolism; Food Handling / methods; Gallic Acid / chemistry; Gallic Acid / metabolism; Gelatin / chemistry; Gelatin / metabolism; Phenols / chemistry; Phenols / metabolism; Proteins / chemistry; Proteins / metabolism; Starch / chemistry; Starch / metabolism
TL;DR:
It was observed that phenolics were less degraded in presence of starch only than in Presence of starch + proteins, and this protection seemed to be linked to the ability of the phenolic compounds to form V-type inclusion complexes with starch, with GA, CAT and EGCG in decreasing order of protection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 30, 2019
2020 journal article
African Adansonia digitata fruit pulp (baobab) modifies provitamin A carotenoid bioaccessibility from composite pearl millet porridges
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 57(4), 1382–1392.
author keywords: Provitamin A carotenoids; Bioaccessibility; Baobab; Micronutrients; Fortification
TL;DR:
The findings suggest that the inhibitory effects on carotenoid micellarization (bioaccessibility) observed with increased baobab addition may not ultimately limit the bioavailability of carotanoids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 9, 2019
2020 journal article
Preference for and sensitivity to flavanol mean degree of polymerization in model wines is correlated with body composition
APPETITE, 144.
author keywords: Astringency; Preference; BMI; Body fat percentage; PROP
MeSH headings : Adipose Tissue; Adult; Body Composition / physiology; Body Mass Index; Body Weight / physiology; Female; Food Preferences / drug effects; Food Preferences / physiology; Humans; Male; Middle Aged; Polymerization; Polyphenols / administration & dosage; Propylthiouracil / administration & dosage; Taste / drug effects; Taste / physiology; Taste Buds / drug effects; Taste Threshold / drug effects; Wine / analysis; Young Adult
TL;DR:
The data suggest that weight status in adults is a greater predictor of liking of flavanol-rich foods than bitterness sensitivity (as determined by PROP classification), and that reduced perception of bitterness and astringency associated with weight gain may impact selection and preference for these foods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 9, 2019
2020 journal article
Starch-phenolic complexes are built on physical CH-pi interactions and can persist after hydrothermal treatments altering hydrodynamic radius and digestibility of model starch-based foods
FOOD CHEMISTRY, 308.
author keywords: Starch; Phenolic acids; Starch digestibility; Hydrodynamic radius; NMR; GC-MS
MeSH headings : Calorimetry, Differential Scanning; Gelatin / chemistry; Hydrodynamics; Phenols / chemistry; Starch / chemistry; Zea mays / chemistry
TL;DR:
Starch-phenolic complexes under hydrothermal treatments suggested that phenolics may complex with starch through non-covalent CH-π bonds along α-(1 → 4) glycosidic chains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 25, 2019
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