Works Published in 2019
Displaying works 141 - 160 of 212 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster
PLOS GENETICS, 15(5).
MeSH headings : Animals; Central Nervous System Stimulants / metabolism; Cocaine / metabolism; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins / antagonists & inhibitors; Dopamine Plasma Membrane Transport Proteins / genetics; Dopamine Plasma Membrane Transport Proteins / metabolism; Dopaminergic Neurons / metabolism; Drosophila Proteins / antagonists & inhibitors; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / drug effects; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Feeding Behavior; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Genome, Insect; Male; Methamphetamine / metabolism; Mushroom Bodies / metabolism; Mushroom Bodies / physiopathology; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; Sex Characteristics; Substance-Related Disorders / genetics; Substance-Related Disorders / metabolism; Substance-Related Disorders / physiopathology
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 24, 2019
2019 journal article
Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing
JOURNAL OF CELL BIOLOGY, 218(6), 1994–2005.
MeSH headings : Animals; Female; Humans; Listeria / growth & development; Listeria / immunology; Listeria / metabolism; Listeriosis / metabolism; Listeriosis / microbiology; Listeriosis / pathology; Listeriosis / prevention & control; Mice; Mice, Inbred C57BL; Mice, Knockout; Necroptosis; Protein Kinases / physiology; Receptor-Interacting Protein Serine-Threonine Kinases / genetics; Receptor-Interacting Protein Serine-Threonine Kinases / metabolism; Receptor-Interacting Protein Serine-Threonine Kinases / physiology
TL;DR:
The RIPK3-MLKL pathway protects epithelial cells from Listeria monocytogenes invasion but does not induce its oligomerization or necroptotic cell death, and instead targets intracellular bacteria and suppresses their replication.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 24, 2019
2019 journal article
Inappropriate Citation of Vaccine Article.
The Journal of Infectious Diseases.
MeSH headings : Humans; Smallpox; Vaccination; Vaccines / adverse effects
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: June 19, 2019
2019 journal article
Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women
CANCER MEDICINE, 8(5), 2503–2513.
author keywords: African ancestry risk; genetic association; ovarian cancer; vitamin D pathway
MeSH headings : Black or African American / genetics; Bayes Theorem; Carcinoma, Ovarian Epithelial / genetics; Carcinoma, Ovarian Epithelial / metabolism; Carcinoma, Ovarian Epithelial / pathology; ErbB Receptors / genetics; Female; Genetic Association Studies; Glucuronosyltransferase / genetics; Humans; Logistic Models; Middle Aged; Neoplasm Grading; Ovarian Neoplasms / genetics; Ovarian Neoplasms / metabolism; Ovarian Neoplasms / pathology; Polymorphism, Single Nucleotide; Receptors, Calcitriol / genetics; Vitamin D / biosynthesis
TL;DR:
Genetic variants in the EGFR and UGT2A1/2 may increase susceptibility of EOC in AA women and the Bayesian False Discovery Probability method was used to evaluate statistical significance of selected SNPs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 17, 2019
2019 journal article
Animal production, insecticide use and self-reported symptoms and diagnoses of COPD, including chronic bronchitis, in the Agricultural Health Study
ENVIRONMENT INTERNATIONAL, 127, 764–772.
author keywords: Epidemiology; Occupational health; Environmental health; Pesticide
MeSH headings : Adult; Animal Husbandry; Animals; Bronchitis, Chronic / epidemiology; Farmers; Female; Humans; Insecticides / toxicity; Logistic Models; Male; Middle Aged; Occupational Exposure; Odds Ratio; Prevalence; Pulmonary Disease, Chronic Obstructive / chemically induced; Pulmonary Disease, Chronic Obstructive / epidemiology; Risk Factors; United States / epidemiology
TL;DR:
Animal production work, including insecticide use, was positively associated with chronic bronchitis symptoms; but not consistently with COPD diagnosis alone; the results support the need for further investigation into the role of animal production-related exposures in the etiology of COPD and better respiratory protection for agricultural workers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019
2019 review
Maternal vitamin D deficiency and developmental origins of health and disease (DOHaD)
[Review of ]. JOURNAL OF ENDOCRINOLOGY, 241(2), R65–R80.
author keywords: vitamin D deficiency; DOHAD; metabolic disorders; autism; neurobehavioral disorders; animal models
TL;DR:
A detailed review and perspective of evidence for the role of maternal VDD in offspring long term health, particularly as it relates to Developmental Origins of Health and Disease (DOHaD), and evidence implicating epigenetic mechanisms as a mediator of this link is explored.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019
2019 journal article
Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis
ANTICANCER RESEARCH, 39(5), 2277–2287.
author keywords: Mammary carcinoma; mammary epithelium; micro-environment; orthotopic tumor model; triple-negative breast cancer
MeSH headings : Animals; Breast Neoplasms / drug therapy; Breast Neoplasms / genetics; Breast Neoplasms / pathology; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Animal / drug therapy; Mammary Neoplasms, Animal / genetics; Mammary Neoplasms, Animal / pathology; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasm Proteins / genetics; Neovascularization, Pathologic / drug therapy; Neovascularization, Pathologic / genetics; Neovascularization, Pathologic / pathology; Tumor Microenvironment / genetics
TL;DR:
Engraftment into the epithelial microenvironment generates tumors that more closely recapitulate the complexity of malignancy, suggesting that intraductal adaptation of orthotopic mammary models may be an important step towards improving outcomes in preclinical drug screening and development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019
2019 journal article
Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse
CHEMICAL RESEARCH IN TOXICOLOGY, 32(5), 887–898.
MeSH headings : Animals; Butadienes / toxicity; Carcinogens, Environmental / toxicity; DNA Adducts / chemistry; DNA Adducts / genetics; DNA Adducts / metabolism; DNA Methylation / drug effects; Epigenesis, Genetic / drug effects; Guanine / analogs & derivatives; Guanine / chemistry; Histones / metabolism; Kidney / drug effects; Liver / drug effects; Lung / drug effects; Male; Mice; Mutagens / toxicity
TL;DR:
1,3-butadiene is used to demonstrate how the Collaborative Cross mouse population can be used to identify the mechanisms for and quantify the degree of interindividual variability in tissue-specific effects that are relevant to chemically induced carcinogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 17, 2019
2019 journal article
The ubiquitin ligase PHR promotes directional regrowth of spinal zebrafish axons
COMMUNICATIONS BIOLOGY, 2(1).
MeSH headings : Actins / metabolism; Adaptor Proteins, Signal Transducing / metabolism; Alleles; Animals; Animals, Genetically Modified; Axons / metabolism; Cadherins / metabolism; Cytoplasmic Dyneins / metabolism; Disease Models, Animal; Green Fluorescent Proteins / metabolism; Image Processing, Computer-Assisted; Ligases / metabolism; MAP Kinase Kinase 4 / metabolism; Mixed Function Oxygenases / metabolism; Mutation; Nerve Regeneration; Neuronal Outgrowth; Spinal Cord / pathology; Spinal Cord Injuries / metabolism; Transgenes; Ubiquitin / metabolism; Zebrafish; Zebrafish Proteins / metabolism
TL;DR:
It is shown that ubiquitin ligase PHR directs the regrowth of zebrafish Mauthner axons after transection, suggesting an important role for these signaling pathways in spinal axonal regrowth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 17, 2019
2019 journal article
Bisphenol F has different effects on preadipocytes differentiation and weight gain in adult mice as compared with Bisphenol A and S
TOXICOLOGY, 420, 66–72.
author keywords: Bisphenol; Metabolism; Fat; BPF; Alternatives to BPA; Diabetes
MeSH headings : 3T3-L1 Cells; Adipocytes / drug effects; Adipocytes / metabolism; Adipogenesis / drug effects; Adipogenesis / genetics; Animals; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Gene Expression Regulation; Male; Mice; Mice, Inbred ICR; Phenols / toxicity; Sulfones / toxicity; Time Factors; Weight Gain / drug effects
TL;DR:
The results suggest that BPS has a strong potential to be obesogenic while effects of BPF are subtler and potentially in the opposite direction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: June 17, 2019
2019 article
The genomics of invasion: characterization of red lionfish (Pterois volitans) populations from the native and introduced ranges (vol 21, pg 2471, 2019)
Reiskind, M. O. B., Reed, E. M. X., Elias, A., Giacomini, J. J., McNear, A. F., Nieuwsma, J., … Williams, B. E. (2019, July). BIOLOGICAL INVASIONS, Vol. 21, pp. 2485–2487.
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019
2019 journal article
The genomics of invasion: characterization of red lionfish (Pterois volitans) populations from the native and introduced ranges
BIOLOGICAL INVASIONS, 21(7), 2471–2483.
author keywords: Invasion; Hybridization; Red lionfish; Pterois volitans; Pterois miles; ddRADseq
TL;DR:
Overall, this study of the red lionfish showed the pattern of introduction and suggested a deeper sampling of genomic data from individuals within the native range may reveal hybridization between species as the source of the aggressive invasion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 17, 2019
2019 journal article
Warmer waters masculinize wild populations of a fish with temperature-dependent sex determination
Scientific Reports, 9(1).
MeSH headings : Animals; Animals, Wild / physiology; Ecosystem; Female; Fishes / anatomy & histology; Fishes / physiology; Gonads / metabolism; Hot Temperature; Male; North Carolina; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sex Determination Processes; Sex Ratio; Water
TL;DR:
Rearing flounder in the laboratory under temperature regimes mimicking those of natural habitats recapitulated sex ratio differences observed across the wild populations, providing strong evidence that temperature is a key factor influencing sex ratios in nursery habitats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 4, 2019
2019 journal article
Cardiac Leiomyosarcoma in a Cat Presenting for Bilateral Renal Neoplasia
JOURNAL OF COMPARATIVE PATHOLOGY, 168, 19–24.
author keywords: cardiac neoplasia; cat; immunohistochemistry; leiomyosarcoma
MeSH headings : Animals; Cat Diseases / pathology; Cats; Female; Heart Neoplasms / veterinary; Kidney Neoplasms / veterinary; Leiomyosarcoma / veterinary
TL;DR:
A 10-year-old neutered female domestic longhair cat was presented to a tertiary care veterinary hospital for evaluation of a right renal mass that was identified incidentally on abdominal radiographs as a sarcoma based on fine needle aspiration cytology, and diagnosed with cardiac leiomyosarcoma with pulmonary and bilateral renal metastasis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Associations between Maternal Tobacco Smoke Exposure and the Cord Blood CD4(+) DNA Methylome
ENVIRONMENTAL HEALTH PERSPECTIVES, 127(4).
MeSH headings : Adult; CD4-Positive T-Lymphocytes / chemistry; DNA Methylation / drug effects; Epigenome / drug effects; Female; Fetal Blood / chemistry; Humans; Male; Maternal Exposure; Tobacco Smoke Pollution / analysis; Young Adult
TL;DR:
Maternal tobacco smoke exposure in pregnancy is associated with cord blood CD4+ DNA methylation in key regulatory regions, including enhancers, and a differentially methylated CpG in amino acid transporter SLC7A8 that is highly reproducible, which may be sensitive to cigarette smoke in both cord blood and adultCD4+ cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
Public questions spur the discovery of new bacterial species associated with lignin bioconversion of industrial waste
ROYAL SOCIETY OPEN SCIENCE, 6(3).
author keywords: greenhouse camel cricket; hide beetle; Cedecea lapagei; lignocellulose; secretome
TL;DR:
This work demonstrates a novel source of lignocellulose-degrading bacteria and introduces an effective workflow to identify bacterial enzymes for transforming industrial waste into value-added products and suggests the value of ecologically guided discovery of novel organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 28, 2019
2019 journal article
Human indoor climate preferences approximate specific geographies
ROYAL SOCIETY OPEN SCIENCE, 6(3).
author keywords: climate dissimilarity; human niche construction; human associates; thermal comfort; indoor biome
TL;DR:
The geographical distribution of the global outdoor climate that is most similar to the interiors of the study homes is identified and a summarized study home indoor climate preferences are summarized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
Electrophysiological Properties of Medium Spiny Neuron Subtypes in the Caudate-Putamen of Prepubertal Male and Female Drd1a-tdTomato Line 6 BAC Transgenic Mice
ENEURO, 6(2).
author keywords: caudate putamen; electrophysiology; intrinsic excitability; medium spiny neurons; rodent; sex differences
MeSH headings : Animals; Corpus Striatum / cytology; Corpus Striatum / physiology; Electrophysiology; Female; Male; Mice; Mice, Transgenic; Neurons / cytology; Neurons / physiology; Organ Culture Techniques; Sex Characteristics; Synaptic Potentials / physiology
TL;DR:
A comprehensive evaluation of mouse caudate-putamen MSN subtype electrophysiological properties across females and males is provided, both confirming and extending previous studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 28, 2019
2019 review
Environmental Chemicals and Autism: A Scoping Review of the Human and Animal Research
[Review of ]. ENVIRONMENTAL HEALTH PERSPECTIVES, 127(4).
MeSH headings : Animals; Autistic Disorder / chemically induced; Environmental Exposure / adverse effects; Environmental Pollutants / adverse effects; Female; Hazardous Substances / adverse effects; Humans; Infant; Infant, Newborn; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Rats
TL;DR:
Chlorpyrifos, lead, and polychlorinated biphenyls (PCBs) are recommended to be systematically reviewed in order to assess their relationship with the development of autism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
Bird community shifts associated with saltwater exposure in coastal forests at the leading edge of rising sea level
PLOS ONE, 14(5).
MeSH headings : Animal Migration / physiology; Animals; Birds / physiology; Climate Change; Ecosystem; Population Dynamics; Salinity; Sea Level Rise; Seawater / analysis
TL;DR:
Though the extent of habitat changes associated with the development of ghost forest was limited, these changes likely are more permanent and may compound over time as sea level rises at an increasing rate, as well as becoming an important driver of forest bird habitat change in coastal regions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 28, 2019
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