Works Published in 2017
Displaying works 161 - 180 of 210 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Stable Transmission of Borrelia burgdorferi Sensu Stricto on the Outer Banks of North Carolina
Zoonoses and Public Health, 64(5), 337–354.
author keywords: Borrelia burgdorferi; Ixodes scapularis; Peromyscus leucopus; Oryzomys palustris; Sylvilagus palustris; Outer Banks; North Carolina
MeSH headings : Animals; Bacteriological Techniques; Borrelia burgdorferi / genetics; Borrelia burgdorferi / isolation & purification; DNA, Bacterial / genetics; Female; Ixodes / microbiology; Lyme Disease / epidemiology; Lyme Disease / microbiology; Lyme Disease / transmission; Lyme Disease / veterinary; Male; North Carolina / epidemiology; Phylogeny; Rabbits / microbiology; Reptiles / microbiology; Rodentia / microbiology
TL;DR:
Two studies indicate that B. burgdorferi sensu stricto is endemic in questing I. scapularis and mammalian tick hosts on the Outer Banks of North Carolina.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Pharmacokinetic analysis of thymol, carvacrol and diallyl disulfide after intramammary and topical applications in healthy organic dairy cattle
Food Additives & Contaminants: Part A, 34(5), 1–10.
author keywords: Mastitis; organic; generally recognised as safe (GRAS); bovine; residue
MeSH headings : Administration, Topical; Allyl Compounds / administration & dosage; Allyl Compounds / pharmacokinetics; Animals; Cattle; Cymenes; Dairying; Disulfides / administration & dosage; Disulfides / pharmacokinetics; Female; Health; Limit of Detection; Mammary Glands, Animal / metabolism; Monoterpenes / administration & dosage; Monoterpenes / pharmacokinetics; Thymol / administration & dosage; Thymol / pharmacokinetics
TL;DR:
The plasma pharmacokinetics of three organic mastitis products currently used by organic producers and organic dairy veterinarians are investigated, finding that levels were measurable in the plasma, liver, kidney and fat up to 72 h after the last dose.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 review
Papillomaviruses in dogs and cats
[Review of ]. VETERINARY JOURNAL, 225, 23–31.
author keywords: Papillomavirus; Canine; Feline; Papillomas; Pigmented plaques
MeSH headings : Animals; Bowen's Disease / veterinary; Carcinoma, Basal Cell / veterinary; Carcinoma, Basal Cell / virology; Carcinoma, Squamous Cell / veterinary; Cat Diseases / virology; Cats; Dog Diseases / virology; Dogs; Mouth Neoplasms / veterinary; Mouth Neoplasms / virology; Papilloma / veterinary; Papilloma / virology; Papillomaviridae / classification; Papillomaviridae / genetics; Papillomaviridae / pathogenicity; Papillomavirus Infections / diagnosis; Papillomavirus Infections / prevention & control; Papillomavirus Infections / veterinary; Skin Neoplasms / veterinary; Skin Neoplasms / virology
TL;DR:
There is increasing evidence that PVs may also be a cause of cutaneous squamouscell carcinomas and basal cell carcinomas in cats, and Diagnostic techniques and possible methods to prevent PV infection are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Nonsteroidal anti-inflammatory drug associated right dorsal colitis in the horse
Pferdeheilkunde, 33(4), 403–405.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Mouse models of acute and chronic hepacivirus infection
SCIENCE, 357(6347), 204-+.
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Disease Models, Animal; Hepacivirus / immunology; Hepatitis C / immunology; Hepatitis C, Chronic / immunology; Immunocompetence / immunology; Immunocompromised Host / immunology; Lymphocyte Depletion; Mice; Mice, Inbred C57BL
TL;DR:
It is shown that an HCV-related hepacivirus discovered in Norway rats can establish high-titer hepatotropic infections in laboratory mice with immunological features resembling those seen in human viral hepatitis, which may provide mechanistic insights into hepatic antiviral immunity, a prerequisite for the development of HCV vaccines.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 article
Manganese-induced sex-specific gut microbiome perturbations in C57BL/6 mice
Chi, L., Gao, B., Bian, X., Tu, P., Ru, H., & Lu, K. (2017, September 15). TOXICOLOGY AND APPLIED PHARMACOLOGY, Vol. 331, pp. 142–153.
author keywords: Manganese exposure; Gut microbiome; Sex-specific toxicity; Gut-brain axis; Metabolome; Metagenomics
MeSH headings : Animals; Female; Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / physiology; Gastrointestinal Tract / drug effects; Gastrointestinal Tract / physiology; Male; Manganese / administration & dosage; Manganese / toxicity; Mice; Mice, Inbred C57BL; Sex Characteristics
TL;DR:
Taken together, this study has demonstrated that Mn2+ exposure perturbs the gut microbiome and its metabolic functions, which highlights the potential role of the Gut microbiome in Mn2- toxicity, particularly its sex‐specific toxic effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 article
Introduction to the special issue highlighting Anaerobe 2016
Cox, L. M., Theriot, C. M., & Fichorova, R. N. (2017, June). ANAEROBE, Vol. 45, pp. 1–2.
MeSH headings : Bacteria, Anaerobic / pathogenicity; Bacterial Infections / diagnosis; Bacterial Infections / epidemiology; Bacterial Infections / therapy; Biomedical Research / trends; Global Health; Microbiology / trends; Tennessee
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Interobserver Agreement Using Histological Scoring of the Canine
JOURNAL OF VETERINARY INTERNAL MEDICINE, 31(3), 778–783.
author keywords: Chronic hepatitis; Dog; Hepatic fibrosis; histological scoring
MeSH headings : Animals; Dog Diseases / pathology; Dogs; Fibrosis; Hepatitis, Animal / pathology; Humans; Liver / pathology; Observer Variation; Pathology, Veterinary / standards; Pathology, Veterinary / statistics & numerical data
TL;DR:
There was fair interobserver agreement when pathologists assessed fibrosis and poor agreement when they assessed necroinflammatory activity in dogs and this suboptimal agreement must be taken into account by clinicians making decisions based on histology reports of the liver.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma
VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 852–867.
author keywords: BCL2; canine; comparative genomic hybridization; fluorescence in situ hybridization; follicular lymphoma; immunohistochemistry
MeSH headings : Animals; DNA Copy Number Variations / genetics; DNA Fingerprinting / veterinary; Dog Diseases / etiology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study / veterinary; Lymphoma, Follicular / etiology; Lymphoma, Follicular / genetics; Lymphoma, Follicular / pathology; Lymphoma, Follicular / veterinary; Male; Risk Factors
TL;DR:
Parallel exploration of canine and human cases may reveal alternative tumour-initiating mechanisms other than BCL2 disruption, yielding a more complete definition of the molecular pathogenesis of FL.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 article
Inhibition of spore germination, growth, and toxin activity of clinically relevant C-difficile strains by gut microbiota derived secondary bile acids
Thanissery, R., Winston, J. A., & Theriot, C. M. (2017, June). ANAEROBE, Vol. 45, pp. 86–100.
author keywords: C. difficile; Bile acids; Gut microbiota; Metabolome; Germination; Growth; Toxin
MeSH headings : Animals; Anti-Bacterial Agents / metabolism; Antibiosis; Bacterial Toxins / metabolism; Bile Acids and Salts / metabolism; Clostridioides difficile / drug effects; Clostridioides difficile / growth & development; Gastrointestinal Microbiome; Gastrointestinal Tract / microbiology; Humans; Mice; Spores, Bacterial / drug effects; Spores, Bacterial / growth & development
TL;DR:
It is shown how clinically relevant C. difficile strains can have different responses when exposed to SBAs present in the gastrointestinal tract, and how these responses vary across all strains and ribotypes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Evaluation of pentablock co-polymer (PTSsol) for sustained topical ocular drug delivery
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 39, 475–483.
author keywords: Ocular; Sustained drug delivery; Pentablock co-polymers; Hydrophobic drugs; Brinzolamide; Hydrophilic drugs
TL;DR:
Ocular retention, tolerability, and sustained pharmacodynamics of a clear topical formulation of brinzolamide (BRZ) in PTS sol pentablock co-polymer suggest that drugs in PTSsol may allow for once a day or less frequent dosing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Big data meets materials science: Training the future generation
American Ceramic Society Bulletin, 96(6), 40–44.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Association of breed and histopathological grade in canine mast cell tumours
VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 829–839.
author keywords: Boxer; dog; epidemiology; genetics; MCT; Pug
MeSH headings : Age Factors; Animals; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Female; Male; Mastocytosis, Cutaneous / etiology; Mastocytosis, Cutaneous / pathology; Mastocytosis, Cutaneous / veterinary; Retrospective Studies; Risk Factors; Sex Factors; Skin Neoplasms / etiology; Skin Neoplasms / pathology; Skin Neoplasms / veterinary; Species Specificity
TL;DR:
The data indicate that the proportion of high-grade tumours increases with advancing age, and that male and intact dogs have increased odds of developing high- grade tumours, and a genetic association for the development ofhigh-grade MCTs is suggested.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 review
A proposed analytic framework for determining the impact of an antimicrobial resistance intervention
[Review of ]. ANIMAL HEALTH RESEARCH REVIEWS, 18(1), 1–25.
author keywords: antimicrobial use; antimicrobial resistance; intervention strategy; analytic framework
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Drug Resistance, Bacterial; Drug Utilization / legislation & jurisprudence; United States; United States Food and Drug Administration
TL;DR:
A system framework to address the methodological gap linking livestock AMU and AMR in foodborne bacteria is proposed, and two methods to model phenotypic AMR changes in bacteria in the food supply and evolutionary genotypic analyses determining molecular changes in phenotypIC AMR are studied.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
Transgenerational endpoints provide increased sensitivity and insight into multigenerational responses of Lymnaea stagnalis exposed to cadmium
ENVIRONMENTAL POLLUTION, 224, 572–580.
author keywords: Evolutionary toxicology; Freshwater invertebrate; Phenotypic plasticity; Multigenerational; Heavy metal
MeSH headings : Animals; Cadmium / toxicity; Dose-Response Relationship, Drug; Drug Tolerance; Ecotoxicology / methods; Endpoint Determination; Lymnaea / drug effects; Lymnaea / growth & development; Lymnaea / physiology; Reproduction / drug effects; Toxicity Tests / methods; Water Pollutants, Chemical / toxicity
TL;DR:
It is found that parental exposure duration has important implications for offspring effects and that contaminant concentrations that are not directly toxic to parents can cause transgenerational changes in resistance that have significant implications for toxicity testing and adaptive responses.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice
PLOS ONE, 12(6).
MeSH headings : Animals; Body Weight / drug effects; Body Weight / genetics; Energy Metabolism / drug effects; Energy Metabolism / genetics; Female; Gastrointestinal Microbiome / drug effects; Lipopolysaccharides / metabolism; Male; Metabolomics / methods; Mice; RNA, Ribosomal, 16S / genetics; Sex Factors; Sweetening Agents / pharmacology; Thiazines / pharmacology; Weight Gain / drug effects
TL;DR:
It is found that Ace-K consumption perturbed the gut microbiome of CD-1 mice after a 4-week treatment, and the observed body weight gain, shifts in the gut bacterial community composition, enrichment of functional bacterial genes related to energy metabolism, and fecal metabolomic changes were highly gender-specific, with differential effects observed for males and females.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Pharmacokinetics of C-14-ortho-phenylphenol following intravenous administration in pigs
JOURNAL OF APPLIED TOXICOLOGY, 37(4), 508–512.
author keywords: pharmacokinetics; ortho-phenylphenol; intravenous dose; pig; biocide
MeSH headings : Administration, Intravenous; Animals; Area Under Curve; Biphenyl Compounds / administration & dosage; Biphenyl Compounds / pharmacokinetics; Disinfectants / pharmacokinetics; Feces / chemistry; Half-Life; Male; Sus scrofa; Swine; Tissue Distribution
TL;DR:
Comparisons with other species suggest that 14C‐OPP clearance in pigs (2.48 ml h–1 kg–1) is less than that in humans and rats and that the kidneys play a crucial role in clearance with a large percentage of the dose being found in the urine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 article
Multi-Omits Reveals that Lead Exposure Disturbs Gut Microbiome Development, Key Metabolites, and Metabolic Pathways
Gao, B., Chi, L., Mahbub, R., Bian, X., Tu, P., Ru, H., & Lu, K. (2017, April). CHEMICAL RESEARCH IN TOXICOLOGY, Vol. 30, pp. 996–1005.
MeSH headings : Animals; Bacteria / genetics; Bacteria / isolation & purification; Bacteria / metabolism; Bacterial Proteins / metabolism; Bile Acids and Salts / metabolism; Carrier Proteins / metabolism; Energy Metabolism / drug effects; Female; Gas Chromatography-Mass Spectrometry; Gastrointestinal Microbiome / drug effects; Gastrointestinal Tract / microbiology; Lead / toxicity; Metabolic Networks and Pathways / drug effects; Metabolome / drug effects; Metabolomics; Mice; Mice, Inbred C57BL; Nitrite Reductases / metabolism; Oxidative Stress / drug effects; RNA, Ribosomal, 16S / chemistry; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 16S / metabolism; Sequence Analysis, DNA; Vitamin E / metabolism
TL;DR:
Gut microbiome toxicity induced by lead exposure in C57BL/6 mice was defined using multiomics approaches, which demonstrated that lead exposure not only altered the gut microbiome community structures/diversity but also greatly affected metabolic functions, leading to gut microbiome toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Improved molecular detection of Babesia infections in animals using a novel quantitative real-time PCR diagnostic assay targeting mitochondrial DNA
PARASITES & VECTORS, 10.
author keywords: Canine babesiosis; Babesia; Mitochondrial DNA; Quantitative PCR
MeSH headings : Animals; Babesia / classification; Babesiosis / diagnosis; Babesiosis / parasitology; DNA, Mitochondrial / genetics; DNA, Protozoan / genetics; Real-Time Polymerase Chain Reaction / methods; Real-Time Polymerase Chain Reaction / veterinary
TL;DR:
A more sensitive qPCR assay with a more expansive range of Babesia spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Guide to FARAD resources: historical and future perspectives
Journal of the American Veterinary Medical Association, 250(10), 1131–1139.
MeSH headings : Animal Husbandry; Animals; Consumer Product Safety; Databases, Factual; Drug Residues; Food Contamination; Meat; United States; United States Department of Agriculture
TL;DR:
The program has dramatically evolved since its inception in terms of data resources, outreach, quantitative tools used to estimate WDIs, precision of estimates, and methods implemented to disseminate information.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
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