Works Published in 2015
Displaying works 181 - 200 of 303 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Surgery of the trachea
Advances in Equine Upper Respiratory Surgery, 261–269.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Rapid tumor induction in zebrafish by TALEN-mediated somatic inactivation of the retinoblastoma1 tumor suppressor rb1
SCIENTIFIC REPORTS, 5.
MeSH headings : Alleles; Animals; Base Sequence; Brain Neoplasms / genetics; Brain Neoplasms / pathology; Cell Transformation, Neoplastic / genetics; Disease Models, Animal; Endonucleases / metabolism; Gene Frequency; Gene Silencing; Gene Targeting; Genetic Loci; Germ Cells / metabolism; Humans; Mitotic Index; Retinoblastoma Protein / chemistry; Retinoblastoma Protein / genetics; Sequence Alignment; Zebrafish
TL;DR:
This is the first demonstration that somatic inactivation of a tumor suppressor causes cancer in zebrafish and highlights the utility of site-specific nucleases to create genetic mosaic zebra fish for tumor suppressionor gene discovery.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Pharmaceutical Activation or Genetic Absence of ClC-2 Alters Tight Junctions During Experimental Colitis
Inflammatory Bowel Diseases, 21(12), 2747–2757.
Contributors: Y. Jin n , T. Pridgen n & A. Blikslager n
author keywords: ClC-2 chloride channel; lubiprostone; tight junctions; inflammatory bowel diseases; intestinal barrier function
MeSH headings : Animals; Blotting, Western; CLC-2 Chloride Channels; Chloride Channel Agonists / pharmacology; Chloride Channels / deficiency; Chloride Channels / drug effects; Colitis / chemically induced; Colitis / drug therapy; Colitis / genetics; Dextran Sulfate; Fluorescent Antibody Technique; Intestinal Mucosa / metabolism; Intestines / drug effects; Lubiprostone / pharmacology; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Permeability / drug effects; Tight Junction Proteins / metabolism; Tight Junctions / drug effects; Tight Junctions / metabolism; Trinitrobenzenes
TL;DR:
A central role for ClC-2 in restoration of barrier function and tight junction architecture in experimental murine colitis is suggested, which can be therapeutically targeted with lubiprostone.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Oral glucocorticoid pulse therapy for induction of treatment of canine pemphigus foliaceus - a comparative study
Veterinary Dermatology, 26(5), 354–e77.
Contributors: P. Bizikova n & T. Olivry n
MeSH headings : Administration, Oral; Animals; Dog Diseases / drug therapy; Dogs; Drug Administration Schedule / veterinary; Glucocorticoids / administration & dosage; Glucocorticoids / therapeutic use; Pemphigus / drug therapy; Remission Induction
TL;DR:
Several benefits associated with oral glucocorticoid pulse therapy are suggested, such as a higher proportion of dogs achieving complete remission (CR) during the first 3 months, a lower average maximal oral glucosuppressive dosage given between pulses and minimal adverse drug events.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2015 journal article
Naturally OccurringEhrlichia ewingiiandMycoplasmasp. Co-Infection in a Goat
Journal of Veterinary Internal Medicine, 29(6), 1735–1738.
author keywords: Caprine; Ehrlichiosis; Tick-borne disease
MeSH headings : Animals; Coinfection / microbiology; Coinfection / veterinary; Ehrlichia / isolation & purification; Ehrlichiosis / complications; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Goat Diseases / microbiology; Goats; Mycoplasma / isolation & purification; Mycoplasma Infections / complications; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Polymerase Chain Reaction; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics
TL;DR:
A 9-year-old nonpregnant, nonlactating doe Boer goat was examined because of a 2-day history of not being able to stand and some degree of chronicity was considered likely.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Modified lamellar keratoplasties for the treatment of deep stromal abscesses in horses
VETERINARY OPHTHALMOLOGY, 18(5), 393–403.
author keywords: deep lamellar endothelial keratoplasty; deep stromal abscess; equine ophthalmology; posterior lamellar keratoplasty; sedation; standing surgery
MeSH headings : Abscess / surgery; Abscess / veterinary; Animals; Corneal Diseases / surgery; Corneal Diseases / veterinary; Corneal Stroma / surgery; Corneal Transplantation / methods; Corneal Transplantation / veterinary; Female; Horse Diseases / surgery; Horses / surgery; Male
TL;DR:
In horses with deep stromal or endothelial abscesses, for which general anesthesia is not an option, both the modified DLEK and PLK corneal procedures may be performed as an alternative to enucleation on the standing, sedated horse.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Management of guttural pouch tympanites
Advances in Equine Upper Respiratory Surgery, 241–248.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Influence of biomechanical parameters on cranial cruciate ligament-deficient or -intact canine stifle joints assessed by use of a computer simulation model
AMERICAN JOURNAL OF VETERINARY RESEARCH, 76(11), 952–958.
MeSH headings : Animals; Anterior Cruciate Ligament / anatomy & histology; Anterior Cruciate Ligament / physiology; Biomechanical Phenomena; Body Weight; Computer Simulation; Dogs; Joints / physiology; Male; Range of Motion, Articular; Rotation; Software; Stifle / anatomy & histology; Stifle / physiology; Tibia / anatomy & histology; Tibia / physiology; Walking
TL;DR:
Computer model sensitivity analyses predicted that CrCL prestrain and body weight influenced stifle joint biomechanics and could play an important role in management of dogs with a CrCL-deficient stifle joints.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
In vitro biomechanical evaluation of internal fixation techniques on the canine lumbosacral junction
PeerJ, 3.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Heparin and LPS-induced COX-2 expression in airway cells: a link between its anti-inflammatory effects and GAG sulfation
EXPERIMENTAL LUNG RESEARCH, 41(9), 499–513.
author keywords: COX-2; heparin; LPS; lung; sulfation
MeSH headings : Anti-Inflammatory Agents, Non-Steroidal / chemistry; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Cell Line; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Gene Expression / drug effects; Glycosaminoglycans / chemistry; Glycosaminoglycans / metabolism; Heparin / chemistry; Heparin / pharmacology; Humans; Interleukin-8 / genetics; Interleukin-8 / metabolism; Lipopolysaccharides / toxicity; MAP Kinase Signaling System / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / drug effects; Respiratory Mucosa / metabolism
TL;DR:
Heparin's anti-inflammatory effects result from its nonspecific suppression of signaling and gene expression and are determined by its sulfation, which may reflect the moderating role of GAG sulfation in lung injury and health.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Fructosamine: An Alternative to Serum Glucose Measurement in White-tailed Deer (Odocoileus virginianus)
JOURNAL OF WILDLIFE DISEASES, 51(4), 876–879.
author keywords: Blood; fructosamine; nutritional condition; Odocoileus virginianus; serum glucose; white-tailed deer
MeSH headings : Animals; Blood Glucose; Deer / blood; Female; Fructosamine / blood; North Carolina; Reference Values
TL;DR:
Serum glucose and fructosamine concentrations were similar between time periods but were uncorrelated within each season, however, when serum glucose was separated into high and low categories based on the median blood glucose score within each time period, it was detected statistically significant differences between July and March for serum glucose.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Effects of high doses of enalapril and benazepril on the pharmacologically activated renin-angiotensin-aldosterone system in clinically normal dogs
AMERICAN JOURNAL OF VETERINARY RESEARCH, 76(12), 1041–1050.
MeSH headings : Aldosterone / blood; Aldosterone / urine; Angiotensin-Converting Enzyme Inhibitors / administration & dosage; Animals; Benzazepines / administration & dosage; Blood Pressure / drug effects; Body Weight / drug effects; Dogs / physiology; Enalapril / administration & dosage; Female; Furosemide / administration & dosage; Heart Rate / drug effects; Male; Peptidyl-Dipeptidase A / blood; Renin-Angiotensin System / drug effects; Time Factors
TL;DR:
Administration of high doses of enalapril and benazepril significantly inhibited ACE activity, yet did not prevent increases in mean urine and serum aldosterone concentrations resulting from furosemide activation of RAAS, suggesting that ald testosterone breakthrough from ACE inhibition was a dose-independent effect of ACE inhibitors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Comparison of two bupivacaine delivery methods to control postoperative pain after enucleation in dogs
VETERINARY OPHTHALMOLOGY, 18(5), 422–428.
author keywords: analgesia; bupivacaine; dogs; enucleation; retrobulbar injection; splash block
MeSH headings : Anesthesia, Local / methods; Anesthesia, Local / veterinary; Anesthetics, Local / administration & dosage; Animals; Bupivacaine / administration & dosage; Dog Diseases / surgery; Dogs; Double-Blind Method; Eye Enucleation / veterinary; Female; Injections, Intraocular / veterinary; Male; Pain Management / methods; Pain Management / veterinary; Pain, Postoperative / drug therapy; Pain, Postoperative / veterinary
TL;DR:
Pain control using an intraoperative orbital splash administration of bupivacaine is not significantly different to a preoperative retrobulbar injection of bu pvacaine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Canine epidermolysis bullosa acquisita: A retrospective study of 20 cases
Veterinary Dermatology, 26(6), 441-.
Contributors: P. Bizikova n, K. Linder n, J. Wofford n, L. Mamo n, S. Dunston n & T. Olivry n
MeSH headings : Aging; Animals; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Epidermolysis Bullosa Acquisita / pathology; Epidermolysis Bullosa Acquisita / veterinary; Female; Immunologic Factors / administration & dosage; Immunologic Factors / therapeutic use; Male; Prednisone / administration & dosage; Prednisone / therapeutic use; Retrospective Studies
TL;DR:
Canine EBA is a rare subepidermal blistering disease with an inflammatory phenotype and a predilection for young great danes and male dogs and the outcome of treatment appears more favourable than assumed previously.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2015 journal article
Canine Stifle Biomechanics Associated With Tibial Tuberosity Advancement Predicted Using a Computer Model
VETERINARY SURGERY, 44(7), 866–873.
MeSH headings : Animals; Anterior Cruciate Ligament / pathology; Biomechanical Phenomena; Computer Simulation; Dogs / surgery; Male; Patellar Ligament; Rotation; Stifle / physiology; Tibia / physiology; Tibia / surgery
TL;DR:
Model-predicted stifle ligament loads improved following tibial tuberosity advancement compared to the CrCL-deficient stifle, but TTA did not restoreCrCL-intact stifle biomechanics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Association of Gallbladder Mucocele Histologic Diagnosis with Selected Drug Use in Dogs: A Matched Case-Control Study
JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(6), 1464–1472.
author keywords: Bile; Canine; Mucus; Xenobiotic
MeSH headings : Animals; Case-Control Studies; Cholinergic Agents / adverse effects; Dog Diseases / chemically induced; Dogs; Female; Gallbladder Diseases / chemically induced; Gallbladder Diseases / veterinary; Hypothyroidism / drug therapy; Imidazoles / adverse effects; Male; Mucocele / chemically induced; Mucocele / pathology; Mucocele / veterinary; Neonicotinoids; Nitro Compounds / adverse effects; Pituitary ACTH Hypersecretion / drug therapy; Pituitary ACTH Hypersecretion / veterinary; Risk Factors; Thyroxine / adverse effects
TL;DR:
This study provides evidence for an association between selected drug use and GBM formation in dogs and exposure to imidacloprid in Shetland sheepdogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Assessment of an implant-skin interface scoring system for external skeletal fixation of dogs
American Journal of Veterinary Research, 76(11), 931–938.
MeSH headings : Animals; Dogs; External Fixators / veterinary; Fracture Fixation; Inflammation; Observer Variation; Orthopedics / methods; Orthopedics / standards; Photography; Reproducibility of Results; Skin / pathology; Veterinary Medicine / methods; Veterinary Medicine / standards
TL;DR:
An ISI scoring system used in this study had high repeatability and agreement and may therefore be considered for use in clinical situations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: August 6, 2018
2015 journal article
Vector-borne pathogens in arctic foxes, Vulpes lagopus, from Canada
Research in Veterinary Science, 99, 58–59.
author keywords: Foxes; Canada; Vector-borne; Bartonella; Mycoplasma; Ehrlichia; Zoonosis
MeSH headings : Anaplasma / genetics; Animals; Babesia / genetics; Babesiosis / epidemiology; Bartonella / genetics; Canada / epidemiology; DNA, Bacterial / genetics; Ehrlichia / genetics; Foxes / blood; Foxes / microbiology; Gram-Negative Bacterial Infections / epidemiology; Mycoplasma / genetics; Polymerase Chain Reaction / veterinary; Prevalence
TL;DR:
Preliminary evidence is provided that vector borne pathogens, not typically associated with the arctic ecosystem, exist at low levels in this arctic fox population, and that vector exposure, pathogen transmission dynamics, and changes in the geographic distribution of pathogens over time should be investigated in future studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
The predictive validity of the ABFM’s in-training examination
Family Medicine, 47(5), 349–356. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929091868&partnerID=MN8TOARS
Contributors: T. O’Neill, Z. Li, M. Peabody, M. Lybarger, K. Royal & J. Puffer
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2015 journal article
Rapid High-Resolution Melt Analysis of Cytauxzoon felis Cytochrome b To Aid in the Prognosis of Cytauxzoonosis
JOURNAL OF CLINICAL MICROBIOLOGY, 53(8), 2517–2524.
MeSH headings : Alleles; Animals; Antiprotozoal Agents / therapeutic use; Atovaquone / therapeutic use; Azithromycin / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Cytochromes b / genetics; Genotype; Genotyping Techniques / methods; Piroplasmida / drug effects; Piroplasmida / genetics; Piroplasmida / isolation & purification; Polymerase Chain Reaction / methods; Prognosis; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / drug therapy; Protozoan Infections, Animal / parasitology; Protozoan Proteins / genetics; Sensitivity and Specificity; Transition Temperature; Veterinary Medicine / methods
TL;DR:
The purpose of this study was to design a PCR panel that could distinguish C. felis cytb1 from other cytochrome b genotypes, and this panel was predicted to distinguish cytb 1 from other cytb genotypes through the use of high-resolution melt analysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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