Works Published in 2018

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Displaying works 81 - 100 of 141 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays

Scientific Reports, 8(1).

Contributors: D. Mahapatra n, J. Franzosa*, K. Roell n, M. Kuenemann n, K. Houck*, D. Reif n, D. Fourches n, S. Kullman n

MeSH headings : Drug Evaluation, Preclinical; Genes, Reporter; High-Throughput Screening Assays; Humans; Luciferases / analysis; Luciferases / genetics; Protein Binding; Receptors, Calcitriol / agonists; Receptors, Calcitriol / antagonists & inhibitors; Two-Hybrid System Techniques; Xenobiotics / metabolism
TL;DR: Data emphasizes the molecular complexity of ligand-mediated interactions with VDR and suggest that VDR transactivation may be a target site of action for diverse xenobiotics. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2018 personal communication

Raw milk consumption and other early-life farm exposures and adult pulmonary function in the Agricultural Lung Health Study

Wyss, A. B., House, J. S., Hoppin, J. A., Richards, M., Hankinson, J. L., Long, S., … London, S. J. (2018, March).

By: A. Wyss*, J. House n, J. Hoppin n, M. Richards*, J. Hankinson, S. Long*, P. Henneberger*, L. Freeman* ...

Contributors: A. Wyss*, J. House n, J. Hoppin n, M. Richards*, J. Hankinson, S. Long*, P. Henneberger*, L. Beane Freeman* ...

author keywords: COPD epidemiology; Asthma Epidemiology; Allergic lung disease; Occupational Lung Disease; Respiratory Measurement
MeSH headings : Adult; Aged; Agriculture; Animals; Case-Control Studies; Child; Child, Preschool; Environmental Exposure; Farms / statistics & numerical data; Female; Humans; Lung / physiopathology; Male; Middle Aged; Milk / physiology; Prospective Studies; Respiratory Physiological Phenomena; Spirometry / methods; United States
TL;DR: A novel association between raw milk consumption and higher pulmonary function that lasts into older adulthood is reported and did not find appreciable associations with other early-life farming exposures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Prenatal Phthalates, Maternal Thyroid Function, and Risk of Attention-Deficit Hyperactivity Disorder in the Norwegian Mother and Child Cohort

ENVIRONMENTAL HEALTH PERSPECTIVES, 126(5).

By: S. Engel*, G. Villanger*, R. Nethery*, C. Thomsen*, A. Sakhi*, S. Drover*, J. Hoppin n, P. Zeiner* ...

MeSH headings : Adult; Attention Deficit Disorder with Hyperactivity / epidemiology; Attention Deficit Disorder with Hyperactivity / urine; Case-Control Studies; Cohort Studies; Female; Humans; Male; Mothers; Phthalic Acids / urine; Pregnancy; Prenatal Exposure Delayed Effects; Surveys and Questionnaires; Thyroid Gland / physiology
TL;DR: In this population-based case–control study of clinical ADHD, maternal urinary concentrations of DEHP were monotonically associated with increased risk of ADHD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Hydrologic characteristics of freshwater mussel habitat: novel insights from modeled flows

FRESHWATER SCIENCE, 37(2), 343–356.

By: C. Drew n, M. Eddy*, T. Kwak n, W. Cope n & T. Augspurger*

author keywords: Unionidae; freshwater mussel; hydrology; Parvaspina steinstansana; endemic species; surrogate species; ordination; altered flow
TL;DR: These findings provide the first demonstrated application of complete, continuous, regional modeled hydrologic data to freshwater mussel distribution and management and highlight the utility of modeling and data-mining methods to facilitate further exploration and application of such modeled environmental conditions to inform aquatic species management. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Effects of Turbidity, Sediment, and Polyacrylamide on Native Freshwater Mussels

JOURNAL OF THE AMERICAN WATER RESOURCES ASSOCIATION, 54(3), 631–643.

By: S. Buczek n, W. Cope n, R. McLaughlin n & T. Kwak n

author keywords: turbidity; invertebrates; toxicology; erosion; best management practices (BMPs); environmental impacts
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Do postlarval amphidromous fishes transport marine-derived nutrients and pollutants to Caribbean streams?

Ecology of Freshwater Fish, 27(3), 847–856.

By: A. Engman n, T. Kwak n & W. Cope n

author keywords: amphidromous; biotransport; contaminants; ecosystem function; stable isotopes; tropical river
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

DNA methylation of imprinted genes at birth is associated with child weight status at birth, 1 year, and 3 years

Clinical Epigenetics, 10.

By: S. Gonzalez-Nahm, M. Mendez, S. Benjamin-Neelon, S. Murphy, V. Hogan, D. Rowley, C. Hoyo

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Consequences of fipronil exposure in egg-laying hens

Journal of the American Veterinary Medical Association, 253(1), 57–60.

By: E. Stafford n, L. Tell, Z. Lin*, J. Davis*, T. Vickroy*, J. Riviere*, R. Baynes n

MeSH headings : Animal Feed / analysis; Animals; Chickens / metabolism; Europe; Female; Food Contamination / prevention & control; Food Safety; Ovum / metabolism; Pesticides / adverse effects; Pyrazoles / adverse effects
TL;DR: Concerns with fipronil use or exposure in poultry and the difficulties associated with developing data-driven meat or egg withdrawal intervals are explained. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Comparison of emerging contaminants in receiving waters downstream of a conventional wastewater treatment plant and a forest-water reuse system

Environmental Science and Pollution Research, 25(13), 12451–12463.

author keywords: Wastewater; Contaminants of emerging concern (CECs); Forest-water reuse; Nontargeted analysis; Surface water; Water reuse
MeSH headings : Agricultural Irrigation; Environmental Monitoring; Forestry / methods; North Carolina; Waste Disposal, Fluid / methods; Wastewater / analysis; Water Pollutants, Chemical / analysis
TL;DR: Data indicate that FWR systems represent a sustainable wastewater treatment alternative and that emerging contaminant release to waterways was lower at a FWR system than a conventional WWTP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi

BIODATA MINING, 11(1).

Contributors: K. To n, R. Fry* & D. Reif n

author keywords: Chemical prioritization; ToxPi; ToxCast; Missing data; Imputation; Multiple imputation; Simulation
TL;DR: Simulation studies around high-throughput screening data generated by the ToxCast and Tox21 programs on chemicals highlighted by the Agency for Toxic Substances and Disease Registry’s Substance Priority List (SPL) can augment confidence in the robustness of decisions regarding the health and ecological effects of environmental chemicals. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Assessment of atrazine toxicity to the estuarine phytoplankter, Dunaliella tertiolecta (Chlorophyta), under varying nutrient conditions

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 25(12), 11409–11423.

author keywords: Atrazine; Ecotoxicity; Dunaliella; Estuarine; Modified algal bioassay; Nitrogen; Phosphorus; Phytoplankton
MeSH headings : Atrazine / toxicity; Chlorophyceae / drug effects; Chlorophyta / drug effects; Herbicides / toxicity; Phytoplankton / drug effects; Phytoplankton / growth & development; Water Pollutants, Chemical / toxicity
TL;DR: Atrazine sensitivity in nutrient-replete media was higher than expected, but sensitivity was influenced by exposure duration, and inhibitory effects of herbicide on algal growth decreased under imbalanced nutrient regimes and low nitrogen and phosphorus supplies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Animal models of endocrine disruption

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 32(3), 283–297.

author keywords: vole; peromyscus; toxicology; neurosciences; collaborative cross; PFOA
MeSH headings : Animals; Disease Models, Animal; Endocrine Disruptors / toxicity; Endocrine System / drug effects; Endocrine System Diseases / chemically induced; Endocrine System Diseases / pathology; Environmental Exposure / adverse effects; Environmental Illness / chemically induced; Environmental Illness / pathology; Humans; Reproducibility of Results; Reproduction / drug effects; Reproduction / physiology
TL;DR: Advances in genomics, neuroimaging and other tools are making a wider range of animal models more widely available to EDC researchers, and a greater diversity of species are used to effectively model more subtle but significant outcomes such as changes in pubertal timing, mammary gland development, and social behaviors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

An empirical Bayes approach for multiple tissue eQTL analysis

Biostatistics (Oxford, England), 19(3), 391–406.

By: G. Li*, A. Shabalin*, I. Rusyn, F. Wright n & A. Nobel*

MeSH headings : Bayes Theorem; Biostatistics / methods; Gene Expression; Genomics / methods; Genotyping Techniques / methods; Humans; Models, Statistical; Quantitative Trait Loci
TL;DR: A hierarchical Bayesian model (MT‐eQTL) for multi‐tissue eQTL analysis that explicitly captures patterns of variation in the presence or absence of eQ TL, as well as the heterogeneity of effect sizes across tissues is developed. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

A zero-inflated beta-binomial model for microbiome data analysis

STAT, 7(1).

By: T. Hu n, P. Gallins n & Y. Zhou n

author keywords: count data; penalized generalized linear model; zero-inflated beta-binomial modelling
TL;DR: A zero‐inflated beta‐binomial is introduced to model the distribution of microbiome count data and to determine association with a continuous or categorical phenotype of interest and has higher power than competing methods to detect taxa associated with phenotype. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2018 journal article

A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making

CURRENT BIOLOGY, 28(9), 1357-+.

By: R. Jain*, M. Wolman*, K. Marsden*, J. Nelson*, H. Shoenhard*, F. Echeverry, C. Szi*, H. Bell* ...

MeSH headings : Acoustic Stimulation; Animals; Behavior, Animal; Calcium / metabolism; Choice Behavior / physiology; Genetic Testing; Mutation; Psychomotor Performance; Receptors, Calcium-Sensing / genetics; Receptors, Calcium-Sensing / physiology; Zebrafish / embryology; Zebrafish / physiology; Zebrafish Proteins / genetics; Zebrafish Proteins / physiology
TL;DR: Zebrafish larvae select a behavioral response to acoustic stimuli from a pre-existing choice repertoire in a context-dependent manner and this sensorimotor choice is modulated by stimulus quality and history, as well as by neuromodulatory systems-all hallmarks of more complex decision making. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Use of a specific polyclonal anti-canine TSLP antibody reveals TSLP expression in normal tissue and cell culture

Journal of Veterinary Pharmacology and Therapeutics, 41, 153–153.

By: J. Ganchingco, J. Yoder & W. Baumer

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Signal transducer and activator of transcription 1 regulates multiwalled carbon nanotube-induced pulmonary fibrosis in mice via suppression of transforming growth factor-beta 1 production and signaling

Annals of the American Thoracic Society, 15, S129–130.

By: K. Duke, A. Taylor, M. Ihrie, K. Shipkowski, E. Needham & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2018 review

Mechanisms of carbon nanotube-induced pulmonary fibrosis: A physicochemical characteristic perspective

[Review of ]. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, 10(3).

By: K. Duke & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2018 article

Introduction to the special issue on endocrine disrupting chemicals and behavior

Barrett, E. S., & Patisaul, H. B. (2018, May). HORMONES AND BEHAVIOR, Vol. 101, pp. 1–2.

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Effects of maternal or paternal bisphenol A exposure on offspring behavior

HORMONES AND BEHAVIOR, 101, 68–76.

By: E. Harris n, H. Allardice n, A. Schenk* & E. Rissman n

MeSH headings : Animals; Anxiety / chemically induced; Anxiety / physiopathology; Behavior, Animal / drug effects; Benzhydryl Compounds / pharmacology; Endocrine Disruptors / pharmacology; Female; Male; Maternal Exposure / adverse effects; Mice; Mice, Inbred C57BL; Paternal Exposure / adverse effects; Phenols / pharmacology; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / physiopathology; Sexual Behavior, Animal / drug effects
TL;DR: These are among the first studies conducted to ask if BPA exposure via the sire affects offspring behavior and the first study to report effects of gestational BPA Exposure on pup USVs and adult operant responding. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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