Works Published in 2012

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Displaying works 121 - 140 of 202 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 journal article

Dietary Long-Chain PUFA Enhance Acute Repair of Ischemia-Injured Intestine of Suckling Pigs

JOURNAL OF NUTRITION, 142(7), 1266–1271.

MeSH headings : Animals; Constriction; Diet; Dietary Fats / pharmacology; Dietary Supplements; Eicosapentaenoic Acid / pharmacology; Electric Impedance; Ileal Diseases / drug therapy; Ileal Diseases / pathology; Ileal Diseases / physiopathology; Ileum / drug effects; Ileum / pathology; Ileum / physiopathology; Intestinal Mucosa / drug effects; Intestinal Mucosa / pathology; Intestinal Mucosa / physiopathology; Inulin / blood; Ischemia / drug therapy; Ischemia / pathology; Ischemia / physiopathology; Mannitol / blood; Mesentery / blood supply; Swine; Wound Healing / drug effects
TL;DR: It is demonstrated that feeding elevated levels of long-chain PUFA enhances acute recovery of ischemia-injured porcine ileum, and a histological evaluation of ischemic ilea from piglets fed the 5% ARA showed reduced histological lesions after ischemIA compared with the other dietary groups. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Defects in small intestinal epithelial barrier function and morphology associated with peri-weaning failure to thrive syndrome (PFTS) in swine

RESEARCH IN VETERINARY SCIENCE, 93(2), 975–982.

By: A. Moeser n, L. Borst n, B. Overman n & J. Pittman*

author keywords: Pigs; Weaning; Intestine; Barrier function; Failure-to-thrive
MeSH headings : Animals; Dextrans; Failure to Thrive / pathology; Failure to Thrive / veterinary; Female; Fluorescein-5-isothiocyanate / analogs & derivatives; Intestinal Mucosa / pathology; Intestine, Small / pathology; Swine; Swine Diseases / pathology; Weaning
TL;DR: It is demonstrated that PFTS is associated with profound disturbances in intestinal epithelial barrier function and alterations in mucosal and epithelial morphology in which anorexia is not the sole factor. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Conjunctivitis, rhinitis, and sinusitis in cliff swallows (Petrochelidon pyrrhonota) found in association with Mycoplasma sturni infection and cryptosporidiosis

AVIAN PATHOLOGY, 41(4), 395–401.

By: D. Ley n, A. Moresco* & S. Frasca*

MeSH headings : Animals; Bird Diseases / drug therapy; Bird Diseases / microbiology; Bird Diseases / parasitology; Bird Diseases / pathology; Coinfection; Conjunctiva / pathology; Conjunctivitis / complications; Conjunctivitis / microbiology; Conjunctivitis / parasitology; Conjunctivitis / veterinary; Cryptosporidiosis / complications; Cryptosporidiosis / pathology; Cryptosporidiosis / veterinary; Cryptosporidium / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Fatal Outcome; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma Infections / complications; Mycoplasma Infections / microbiology; Mycoplasma Infections / pathology; Mycoplasma Infections / veterinary; Nasal Septum / pathology; RNA, Ribosomal, 16S / genetics; Rhinitis / complications; Rhinitis / microbiology; Rhinitis / parasitology; Rhinitis / veterinary; Sequence Analysis, DNA; Sinusitis / complications; Sinusitis / microbiology; Sinusitis / parasitology; Sinusitis / veterinary; Swallows; Turbinates / pathology
TL;DR: Identification of concurrent M. sturni and Cryptosporidium spp. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Characterization of Immune Cell Infiltration Into Canine Intracranial Meningiomas

VETERINARY PATHOLOGY, 49(5), 784–795.

By: L. Boozer n, T. Davis n, L. Borst n, K. Zseltvay n, N. Olby n & C. Mariani n

author keywords: brain; dog; immunohistochemistry; lymphocyte; meningioma; microglia; Toll-like receptor; tumor
MeSH headings : Animals; Antigens, CD / analysis; Antigens, CD / immunology; Biomarkers, Tumor / metabolism; Cytokines / metabolism; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Forkhead Transcription Factors / metabolism; Immunohistochemistry / veterinary; Lymphocyte Subsets / immunology; Lymphocytes, Tumor-Infiltrating / immunology; Macrophages / immunology; Male; Meningeal Neoplasms / immunology; Meningeal Neoplasms / pathology; Meningeal Neoplasms / veterinary; Meningioma / immunology; Meningioma / pathology; Meningioma / veterinary; Paraffin Embedding / veterinary; Toll-Like Receptor 4 / metabolism; Toll-Like Receptor 9 / metabolism
TL;DR: Investigation of the presence of a variety of immune cell subsets within canine intracranial meningiomas suggests that evaluation of this immune cell infiltrate may provide important prognostic information and may be useful in the design of novel therapies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

BODY TEMPERATURES OF SELECTED AMPHIBIAN AND REPTILE SPECIES

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 43(3), 517–521.

By: M. Raske n, G. Lewbart*, D. Dombrowski*, P. Hale, M. Correa & L. Christian*

author keywords: Amphibians; reptiles; ectotherm; body temperature
MeSH headings : Amphibians / classification; Amphibians / physiology; Animals; Body Temperature Regulation / physiology; Reptiles / classification; Reptiles / physiology; Species Specificity
TL;DR: This study indicates some ectotherms are able to regulate their body temperatures independent of their environment and Investigation of basic physiologic parameters (heart rate, respiratory rate, and body temperature) from a diverse population of healthy ectothermic vertebrates may provide baseline data for a systematic health care approach. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

What is your diagnosis? Cerebrospinal fluid from a dog

VETERINARY CLINICAL PATHOLOGY, 41(3), 429–430.

By: D. Stowe n, C. Escobar n & J. Neel n

Contributors: D. Stowe n, C. Escobar n & J. Neel n

author keywords: Canine; dendritic cell; histiocytic sarcoma; immunocytochemistry
MeSH headings : Animals; CD11c Antigen / cerebrospinal fluid; Dendritic Cells / pathology; Diagnosis, Differential; Dog Diseases / cerebrospinal fluid; Dog Diseases / pathology; Dogs; Histiocytic Sarcoma / cerebrospinal fluid; Histiocytic Sarcoma / pathology; Histiocytic Sarcoma / veterinary; Immunophenotyping / veterinary; Magnetic Resonance Imaging / veterinary; Male; Prognosis
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

WNT7B in fibroblastic foci of idiopathic pulmonary fibrosis

Respiratory Research, 13(1), 62.

By: T. Meuten n, A. Hickey n, K. Franklin n, B. Grossi n, J. Tobias n, D. Newman n, S. Jennings n, M. Correa n, P. Sannes n

author keywords: Myofibroblasts; Alveolar epithelium; Interstitial lung disease
MeSH headings : Aged; Aged, 80 and over; Basement Membrane / pathology; Female; Fibroblasts / pathology; Humans; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Macrophages / pathology; Male; Middle Aged; Muscle, Smooth / pathology; Respiratory Mucosa / pathology; Respiratory System / blood supply; Respiratory System / pathology; Severity of Illness Index; Wnt Proteins / analysis; Wnt Proteins / metabolism
TL;DR: Tissue samples from the Lung Tissue Research Consortium of 39 patients diagnosed with mild to severe IPF/usual interstitial pneumonia and 19 normal patients were examined for the immunolocalization of Wnt7B, demonstrating Wnt 7B to be expressed at high concentrations in regions of active hyperplasia, metaplasia and fibrotic change in IPF patients. (via Semantic Scholar)
Sources: Crossref, Web Of Science
Added: August 6, 2018

2012 journal article

Reversion to Subgroup J Avian Leukosis Virus Viremia in Seroconverted Adult Meat-Type Chickens Exposed to Chronic Stress by Adrenocorticotrophin Treatment

AVIAN DISEASES, 56(3), 578–582.

By: A. Pandiri*, I. Gimeno n, J. Mays*, W. Reed* & A. Fadly*

author keywords: stress; avian leukosis virus subgroup j; viremia; shedding; adrenocorticotrophin treatment; meat-type chickens; reversion to viremia
MeSH headings : Adrenocorticotropic Hormone / administration & dosage; Adrenocorticotropic Hormone / toxicity; Animals; Antibodies, Viral; Avian Leukosis / immunology; Avian Leukosis / virology; Avian Leukosis Virus / classification; Avian Leukosis Virus / genetics; Chickens; Male; Poultry Diseases / virology; Stress, Physiological / drug effects; Stress, Physiological / immunology; Viremia
TL;DR: It is suggested that treatment of chickens with ACTH can cause reversion of viremia and cloacal shedding in ALV J–seroconverted adult male chickens that had been exposed to the virus at hatch, but not in chickens that were contact-exposed at 32 wk of age. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 article

Quantitative Risk Assessment Methods for Cancer and Noncancer Effects

TOXICOLOGY AND HUMAN ENVIRONMENTS, Vol. 112, pp. 259–283.

By: R. Baynes n

MeSH headings : Hazardous Substances / toxicity; Humans; Models, Chemical; Neoplasms / pathology; No-Observed-Adverse-Effect Level; Risk Assessment / methods; Risk Factors
TL;DR: This chapter briefly describes some of the approaches as described in the guidance documents from several of the regulatory agencies as it pertains to hazard identification and dose-response assessment of a chemical. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Nucleic acid scavengers inhibit thrombosis without increasing bleeding

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(32), 12938–12943.

author keywords: polyphosphates/DNA/RNA; platelet; hemorrhage
MeSH headings : Animals; Blood Coagulation / drug effects; Calorimetry; Carotid Artery Injuries / drug therapy; Fibrinolytic Agents / pharmacology; Mice; Nucleic Acids / metabolism; Polyphosphates / pharmacology; Pulmonary Embolism / drug therapy; Thrombelastography; Thrombosis / drug therapy
TL;DR: It is indicated that nucleic acid-binding polymers are able to scavenge effectively prothrombotic nucleic acids and other polyphosphates in vivo and represent a new and potentially safer class of antithromBotic agents. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Evaluation of diode endoscopic cyclophotocoagulation in bovine cadaver eyes

AMERICAN JOURNAL OF VETERINARY RESEARCH, 73(9), 1445–1452.

By: J. Harrington n, R. McMullen, J. Cullen* & B. Gilger*

MeSH headings : Animals; Cadaver; Cattle; Cattle Diseases / pathology; Cattle Diseases / surgery; Endoscopy / methods; Endoscopy / veterinary; Glaucoma / pathology; Glaucoma / surgery; Glaucoma / veterinary; Histocytochemistry; Laser Coagulation / instrumentation; Laser Coagulation / methods; Laser Coagulation / veterinary
TL;DR: Evaluating the anterior chamber approach and energy levels for endoscopic cyclophotocoagulation (ECPC) and assessing ECPC-induced tissue damage in phakic eyes of bovine cadavers found the 0.75- and 0.90-J energy levels had the potential to effectively treat the ciliary epithelium. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Epidemic protection zones: Centred on cases or based on connectivity?

Transboundary and Emerging Diseases, 59(5), 464–469.

By: A. Rivas, F. Fasina, J. Hammond, S. Smith, A. Hoogesteijn, J. Febles, J. Hittner, D. Perkins

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Connecting Network Properties of Rapidly Disseminating Epizoonotics

PLoS One, 7(6).

By: A. Rivas, F. Fasina, A. Hoogesteyn, S. Konah, J. Febles, D. Perkins, J. Hyman, J. Fair, J. Hittner, S. Smith

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Congenital Adrenal Hyperplasia Associated with Mutation in an 11 ss-Hydroxylase-Like Gene in a Cat

JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(5), 1221–1226.

By: S. Owens*, M. Downey n, B. Pressler*, A. Birkenheuer n, D. Chandler & J. Scott-Moncrieff*

author keywords: Androgen; Feline; Hermaphrodite; Hypertension
MeSH headings : Adrenal Hyperplasia, Congenital / enzymology; Adrenal Hyperplasia, Congenital / genetics; Adrenal Hyperplasia, Congenital / veterinary; Animals; Cat Diseases / enzymology; Cat Diseases / genetics; Cats; DNA / chemistry; DNA / genetics; Male; Point Mutation; Polymerase Chain Reaction / veterinary; Sequence Analysis, DNA; Steroid 11-beta-Hydroxylase / genetics
Source: Web Of Science
Added: August 6, 2018

2012 journal article

CRF Induces Intestinal Epithelial Barrier Injury via the Release of Mast Cell Proteases and TNF-alpha

PLOS ONE, 7(6).

By: E. Overman n, J. Rivier* & A. Moeser n

MeSH headings : Animals; Cell Degranulation / drug effects; Corticotropin-Releasing Hormone / pharmacology; Dextrans; Enteric Nervous System / drug effects; Enteric Nervous System / pathology; Fluorescein-5-isothiocyanate / analogs & derivatives; Ileum / drug effects; Ileum / pathology; Ileum / physiopathology; In Vitro Techniques; Intestinal Mucosa / drug effects; Intestinal Mucosa / injuries; Intestinal Mucosa / pathology; Intestinal Mucosa / physiopathology; Mast Cells / drug effects; Mast Cells / enzymology; Mast Cells / physiology; Molecular Weight; Neutralization Tests; Occludin / metabolism; Peptide Fragments / pharmacology; Peptide Hydrolases / metabolism; Permeability / drug effects; Protease Inhibitors / pharmacology; Protein Transport / drug effects; Rats; Sus scrofa; Tumor Necrosis Factor-alpha / antagonists & inhibitors; Tumor Necrosis Factor-alpha / metabolism
TL;DR: Investigating the mechanisms by which CRF mediates intestinal epithelial barrier disturbances demonstrated that CRF triggers increases in intestinal paracellular permeability via mast cell dependent release of TNF-α and proteases, hallmarks of IBS and IBD. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Antimicrobial resistance, toxinotype, and genotypic profiling of clostridium difficile isolates of swine origin

Journal of Clinical Microbiology, 50(7), 2366–2372.

By: P. Fry*, S. Thakur n, M. Abley* & W. Gebreyes*

MeSH headings : Animals; Bacterial Toxins / genetics; Clostridioides difficile / drug effects; Clostridioides difficile / genetics; Clostridioides difficile / isolation & purification; Clostridioides difficile / pathogenicity; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Feces / microbiology; Genes, Bacterial; Genotype; Humans; Molecular Typing; North Carolina; Ohio; Phylogeography; Polymerase Chain Reaction; Sequence Analysis, DNA; Swine
TL;DR: The study findings indicate that significant proportions of C. difficile in swine are toxigenic and often are associated with antimicrobial resistance genes, although they are not resistant to drugs that are used to treat C.difficile infections. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2012 journal article

Acute myeloblastic leukemia with associated BCR-ABL translocation in a dog

VETERINARY CLINICAL PATHOLOGY, 41(3), 362–368.

By: J. Figueiredo*, S. Culver n, E. Behling-Kelly*, M. Breen n & K. Friedrichs*

author keywords: Cytogenetics; FISH; immunophenotyping; Raleigh chromosome
MeSH headings : Animals; Bone Marrow / pathology; Cytogenetic Analysis / veterinary; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Fusion Proteins, bcr-abl / genetics; Hematologic Tests / veterinary; Immunophenotyping / veterinary; In Situ Hybridization, Fluorescence / veterinary; Leukemia, Myeloid, Acute / genetics; Leukemia, Myeloid, Acute / immunology; Leukemia, Myeloid, Acute / pathology; Leukemia, Myeloid, Acute / veterinary; Male; Translocation, Genetic / genetics
TL;DR: This is the first report of AML with a BCR-ABL translocation in a domestic animal and large multinucleated cells were observed frequently, supporting megakaryocytic lineage. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Validation of a novel epicutaneous delivery system for patch testing of house dust mite-hypersensitive dogs

Veterinary Dermatology, 23(6).

By: T. Olivry, K. Linder, J. Paps, P. Bizikova, S. Dunston, N. Donne, L. Mondoulet

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Morphologic and Molecular Analysis of 39 Spontaneous Feline Pulmonary Carcinomas

VETERINARY PATHOLOGY, 49(6), 971–978.

By: . S. D'Costa, B. Yoon n, D. Kim*, A. Motsinger-Reif n, M. Williams n & Y. Kim n

author keywords: cat; lung cancer; immunohistochemistry; thyroid transcription factor-1; surfactant protein a; epidermal growth factor receptor; p53
MeSH headings : Adenocarcinoma / metabolism; Adenocarcinoma / pathology; Adenocarcinoma / veterinary; Adenocarcinoma, Bronchiolo-Alveolar / metabolism; Adenocarcinoma, Bronchiolo-Alveolar / pathology; Adenocarcinoma, Bronchiolo-Alveolar / veterinary; Animals; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Carcinoma, Adenosquamous / metabolism; Carcinoma, Adenosquamous / pathology; Carcinoma, Adenosquamous / veterinary; Cat Diseases / genetics; Cat Diseases / metabolism; Cat Diseases / pathology; Cats; DNA, Neoplasm / chemistry; DNA, Neoplasm / genetics; ErbB Receptors / genetics; ErbB Receptors / metabolism; Female; Immunohistochemistry / veterinary; Incidence; Lung Neoplasms / metabolism; Lung Neoplasms / pathology; Lung Neoplasms / veterinary; Male; Neoplasm Metastasis; North Carolina; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Pulmonary Surfactant-Associated Protein A / genetics; Pulmonary Surfactant-Associated Protein A / metabolism; Sequence Analysis, DNA / veterinary; Thyroid Nuclear Factor 1; Transcription Factors / genetics; Transcription Factors / metabolism; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / metabolism
TL;DR: Results indicate that primary lung carcinomas are rare but aggressive tumors in cats, thereby warranting further studies on molecular carcinogenesis. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 article

Functional Recognition of the Modified Human tRNA (Lys3) (UUU) Anticodon Domain by HIV's Nucleocapsid Protein and a Peptide Mimic (vol 410, pg 698, year 2011)

Journal of Molecular Biology, Vol. 420, pp. 259–259.

By: W. Graham, L. Barley-Maloney, C. Stark, A. Kaur, C. Stolarchuk, B. Sproat, G. Leszczynska, A. Malkiewicz ...

Source: NC State University Libraries
Added: August 6, 2018

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