Works Published in 2017
Displaying works 61 - 78 of 78 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Wild blueberry polyphenol-protein food ingredients produced by three drying methods: Comparative physico-chemical properties, phytochemical content, and stability during storage
FOOD CHEMISTRY, 235, 76–85.
Contributors: R. Correia n, M. Grace n , D. Esposito n & M. Lila n
author keywords: Soy protein isolate; By-products; Spray drying; Phenolics; Shelf life
MeSH headings : Anthocyanins / analysis; Antioxidants; Blueberry Plants / chemistry; Desiccation / methods; Food Handling / methods; Freeze Drying; Phytochemicals; Polyphenols
TL;DR:
Overall, spray drying the blueberry extracts complexed with protein proved to be an environment-friendly strategy to produce stable functional ingredients with multiple applications for the food industry.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
Thiazolopyridines Improve Adipocyte Function by Inhibiting 11 Beta-HSD1 Oxoreductase Activity
JOURNAL OF CHEMISTRY, 2017.
Contributors: T. Rathinasabapathy* , K. Palatini Jackson, Y. Thor n, A. Buru *, D. Esposito n , X. Li n , M. Pichika *, A. Hamzah*, S. Komarnytsky n
TL;DR:
The tetrahydrothiazolopyridine moiety served as an active pharmacophore for inhibiting 11β-HSD1 and offered a novel therapeutic strategy to ameliorate metabolic alterations found in obesity and diabetes.
(via Semantic Scholar)
downloads.hindawi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
One-step isolation of carnosic acid and carnosol from rosemary by centrifugal partition chromatography
JOURNAL OF SEPARATION SCIENCE, 40(5), 1057–1062.
author keywords: carnosic acid; carnosol; centrifugal partition chromatography; Rosmarinus officinalis
MeSH headings : Abietanes / isolation & purification; Chromatography; Plant Extracts / chemistry; Rosmarinus / chemistry
TL;DR:
Carnosic acid and carnosol are the main bioactive components responsible for the significant antioxidant activity of Rosmarinus officinalis and were identified by mass spectrometry, tandem mass spectromaetry, and comparison with authentic standards.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Metabolic Effects of Berries with Structurally Diverse Anthocyanins
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18(2).
Contributors: J. Overall n , S. Bonney n, M. Wilson n, A. Beermann n, M. Grace n , D. Esposito n , M. Lila n , S. Komarnytsky n
author keywords: berry; gut microbiome; obesity; inflammation; functional food
MeSH headings : Animal Feed; Animals; Anthocyanins / chemistry; Anthocyanins / metabolism; Body Composition; Body Weight; Chromatography, High Pressure Liquid; Dietary Supplements; Feces / chemistry; Fruit / metabolism; Gastrointestinal Microbiome; Glucose / metabolism; Humans; Insulin Resistance; Mice; Molecular Structure; Oxygen Consumption
TL;DR:
Examination of effects of six berries with structurally diverse anthocyanin profiles on development of metabolic risk factors in the C57BL/6 mouse model of polygenic obesity showed a prominent discrepancy between biological activities of delphinidin/malvidin-versus cyanidin-type anthocianins that could be explained by differences in their structure and metabolism in the gut.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Inter- and intra-seasonal changes in anthocyanin accumulation and global metabolite profiling of six blueberry genotypes
JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 59, 105–110.
Contributors: M. Timmers n, M. Grace n , G. Yousef n & M. Lila n
author keywords: Anthocyanin; HPLC; PCA; Blueberry; Metabolite profile; Genotype and seasonal variations; Food analysis; Food composition
TL;DR:
Genotypes were easily distinguished from one another across each harvest season, indicating that each genotype had distinctly different metabolite profile, whereas each of the rabbiteye genotypes overlapped on the scores plot, indicating commonalities in metabolite profiles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Antibacterial activity of medicinal plants from The Physicians of Myddvai, a 14th century Welsh medical manuscript
JOURNAL OF ETHNOPHARMACOLOGY, 203, 171–181.
author keywords: Traditional use; ethnobotany; medicinal plants; microbial infections; antibiotics
MeSH headings : Anti-Bacterial Agents / history; Anti-Bacterial Agents / isolation & purification; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Bacterial Infections / drug therapy; Bacterial Infections / history; Ethnobotany / history; Ethnopharmacology / history; History, Medieval; Humans; Medicine, Traditional / history; Phytotherapy / history; Phytotherapy / methods; Plant Preparations / history; Plant Preparations / pharmacology; Plants, Medicinal / chemistry; Scotland
TL;DR:
Using historical medical sources such as those associated with traditional Celtic medicine to guide rigorous, evidence-based scientific investigation, provides additional leads for new and alternative bioactive molecules for combating bacterial diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
Genetic dissection of sorghum grain quality traits using diverse and segregating populations
THEORETICAL AND APPLIED GENETICS, 130(4), 697–716.
MeSH headings : Amylose / chemistry; Chromosome Mapping; Edible Grain / chemistry; Edible Grain / genetics; Fats / chemistry; Genetic Association Studies; Genetic Linkage; Genetic Markers; Genetics, Population; Genotype; Nutritive Value; Phenotype; Plant Proteins / chemistry; Quantitative Trait Loci; Sorghum / chemistry; Sorghum / genetics; Starch / chemistry; Texas
TL;DR:
Coordinated association and linkage mapping identified 25 grain quality QTLs in multiple environments, and fine mapping of the Wxlocus supports the use of high-density genetic markers in linkage mapping, suggesting higher resolution mapping in recombinant inbred line (RIL) populations can be obtained when genotyped at a high marker density.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Adaptation in Caco-2 Human Intestinal Cell Differentiation and Phenolic Transport with Chronic Exposure to Blackberry (Rubus sp.) Extract
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 65(13), 2694–2701.
author keywords: anthocyanins; bioavailability; blackberry; Caco-2; phenolics
MeSH headings : ATP-Binding Cassette Transporters / metabolism; Biological Transport; Caco-2 Cells; Cell Differentiation; Fruit / metabolism; Glucuronosyltransferase / metabolism; Humans; Intestinal Mucosa / metabolism; Intestines / cytology; Intestines / enzymology; Phenols / metabolism; Plant Extracts / metabolism; Rubus / metabolism
TL;DR:
Adaptation to blackberry extract exposure may impact intestinal transport and metabolism of phenolics, and alterations in mRNA expression of key phase II metabolizing enzymes and transport proteins were observed with treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
A naturally occurring conditional albino mutant in rice caused by defects in the plastid-localized OsABCI8 transporter
Plant Molecular Biology, 94(1-2), 137–148.
author keywords: Rice; ABC transporter; Iron transport; Chloroplast development
MeSH headings : Amino Acid Sequence; Arabidopsis / metabolism; Biological Transport; Carrier Proteins / genetics; Carrier Proteins / metabolism; Chloroplasts; Cloning, Molecular; Gene Expression Regulation, Plant / physiology; Iron / metabolism; Mutation; Oryza / genetics; Phylogeny; Plant Proteins / genetics; Plant Proteins / metabolism; Plastids / metabolism
TL;DR:
It is demonstrated that OsABCI8 represents a conserved ABCI protein involved in transition metals transportation and/or homeostasis and suggest an important role of the plastid-localized Os ABCI8 for chloroplast development.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Protein-bound Vaccinium fruit polyphenols decrease IgE binding to peanut allergens and RBL-2H3 mast cell degranulation in vitro
FOOD & FUNCTION, 8(4), 1611–1621.
MeSH headings : Allergens / immunology; Arachis / immunology; Cell Degranulation / drug effects; Fruit / chemistry; Humans; Immunoglobulin E / immunology; Mast Cells / drug effects; Mast Cells / immunology; Mast Cells / physiology; Peanut Hypersensitivity / drug therapy; Peanut Hypersensitivity / immunology; Plant Extracts / pharmacology; Plant Proteins / immunology; Polyphenols / pharmacology; Vaccinium / chemistry
TL;DR:
The modification of peanut proteins with cranberry or blueberry polyphenols led to the formation of peanut protein-polyphenol complexes with significantly reduced allergenic potential.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 journal article
Modulation of Chloride Currents in Human Lung Epithelial Cells Exposed to Exogenous Oxidative Stress
JOURNAL OF CELLULAR PHYSIOLOGY, 232(7), 1817–1825.
MeSH headings : A549 Cells; Chloride Channels / metabolism; Electrophysiological Phenomena / drug effects; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Lung / pathology; Oxidative Stress / drug effects; Ozone / pharmacology; Patch-Clamp Techniques; Protective Agents / pharmacology; Vitamin E / pharmacology
TL;DR:
The data suggest that ozone exposure is able to modify chloride current density and the use of vitamin E can prevent the above‐mentioned damage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 article
In vitro Hypoallergenicity of Peanut Protein-Blueberry Polyphenol Aggregate Particles
Plundrich, N., Bansode, R., Williams, L., & Lila, M. A. (2017, February). JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol. 139, pp. AB139–AB139.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 article
Anthocyanins and Flavanones Are More Bioavailable than Previously Perceived: A Review of Recent Evidence
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 8, Vol. 8, pp. 155–180.
author keywords: anthocyanins; flavanones; bioavailability; bioactivity
MeSH headings : Anthocyanins / pharmacokinetics; Anthocyanins / urine; Biological Availability; Colon / metabolism; Colon / microbiology; Diet; Flavanones / pharmacokinetics; Flavanones / urine; Fruit / metabolism; Gastrointestinal Microbiome; Humans; Kidney / metabolism; Phenols / pharmacokinetics; Vegetables / metabolism
TL;DR:
It is evident that lower molecular weight phenolic and aromatic ring-fission catabolites, produced primarily by the action of the colonic microbiota, are much more bioavailable than previously envisaged.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2017 journal article
Identification of a residue responsible for UDP-sugar donor selectivity of a dihydroxybenzoic acid glycosyltransferase from Arabidopsis natural accessions
PLANT JOURNAL, 89(2), 195–203.
author keywords: plant secondary metabolism; UGT; substrate specificity; natural variation; Arabidopsis thaliana; dihydroxybenzoic acid
MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Gentisates / metabolism; Glucuronosyltransferase / chemistry; Glucuronosyltransferase / genetics; Glucuronosyltransferase / metabolism; Hydroxybenzoates / metabolism; Mutagenesis, Site-Directed; Polymorphism, Genetic; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity
TL;DR:
Natural variation in Arabidopsis UGT89A2 guided the discovery that a single amino acid residue change determines UDP‐sugar donor selectivity of the dihydroxybenzoic acid glycosyltransferase, providing new insights into UDP‐xylose specificity of a class of enzymes important to specialized metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
alpha-Amylase and alpha-Glucosidase inhibitory activities of phenolic extracts from Eucalyptus grandis x E-urophylla Bark
Journal of Chemistry.
Source: NC State University Libraries
Added: August 6, 2018
2017 review
On the demand for agritourism: a cursory review of methodologies and practice
[Review of ]. TOURISM PLANNING & DEVELOPMENT, 14(1), 139–148.
author keywords: Agritourism; demand; stated preference; revealed preference; tourism flow
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts
FOOD & FUNCTION, 8(1), 111–121.
MeSH headings : Biological Transport; Caco-2 Cells; Catechin / analogs & derivatives; Catechin / metabolism; Catechol O-Methyltransferase / genetics; Catechol O-Methyltransferase / metabolism; Cell Differentiation; Flavonoids / metabolism; Humans; Intestinal Mucosa / metabolism; Intestines / cytology; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins / genetics; Multidrug Resistance-Associated Proteins / metabolism
TL;DR:
The results suggest that intestinal adaptation to both isolated flavan-3-ols and extracts rich in these compounds alters their intestinal transport and metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Changes in phenolic content of commercial potato varieties through industrial processing and fresh preparation
FOOD CHEMISTRY, 218, 47–55.
author keywords: Potato; Potato products; Phenolics; Chlorogenic acid; Anthocyanin; Processing stability
MeSH headings : Anthocyanins / analysis; Chlorogenic Acid / analysis; Food Analysis; Food Handling; Phenols / analysis; Phytochemicals / analysis; Solanum tuberosum / chemistry; Solanum tuberosum / classification
TL;DR:
Overall, industrially processed potato products compare favorably to fresh preparation in levels and recovery of phenolics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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