Works Published in 2020

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Displaying works 181 - 200 of 249 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish

Journal of Immunotoxicology, 17(1), 94–104.

author keywords: Chemical screen; high throughput; phagocyte; reactive oxygen species (ROS); polycyclic aromatic hydrocarbons (PAH); endocrine disrupting compounds (EDC); lead
MeSH headings : Animals; Animals, Genetically Modified; Benzo(a)pyrene / adverse effects; Blood Cell Count; Cytotoxicity Tests, Immunologic / methods; Embryo, Nonmammalian; Estradiol / adverse effects; Feasibility Studies; High-Throughput Screening Assays / methods; Immunity, Innate / drug effects; Macrophages / drug effects; Macrophages / immunology; Methoxychlor / adverse effects; Neutrophils / drug effects; Neutrophils / immunology; Organometallic Compounds / adverse effects; Phenanthrenes / adverse effects; Reactive Oxygen Species / analysis; Reactive Oxygen Species / metabolism; Respiratory Burst / drug effects; Respiratory Burst / immunology; Zebrafish
TL;DR: The utility of zebrafish larvae as a vertebrate model for identifying compounds that impact innate immune function at non-teratogenic levels is demonstrated and validates measuring ROS production and phagocyte numbers as metrics for monitoring how xenobiotic exposure alters the innate immune system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: May 15, 2020

2020 journal article

STEM gender stereotypes from early childhood through adolescence at informal science centers

JOURNAL OF APPLIED DEVELOPMENTAL PSYCHOLOGY, 67.

By: L. McGuire*, K. Mulvey n, E. Goff n, M. Irvin*, M. Winterbottom*, G. Fields*, A. Hartstone-Rose n, A. Rutland*

author keywords: STEM stereotypes; Gender stereotypes; Informal settings
TL;DR: Early childhood is highlighted as a key developmental window in which to challenge ideas about who can and should be proficient in STEM. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
10. Reduced Inequalities (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020

2020 journal article

A refined temporal framework for newly discovered fossil assemblages of the upper Cedar Mountain Formation (Mussentuchit Member), Mussentuchit Wash, Central Utah

CRETACEOUS RESEARCH, 110.

author keywords: Cedar Mountain Formation; Mussentuchit Wash; Mussentuchit Member; UePb geochronology; Chronostratigraphy
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020

2020 journal article

Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster

G3-GENES GENOMES GENETICS, 10(3), 1087–1098.

By: G. Parker n, N. Kohn, A. Spirina, A. McMillen, W. Huang* & T. Mackay n

author keywords: Laboratory evolution; candidate genes; RNAi
MeSH headings : Aging / genetics; Animals; Drosophila melanogaster / genetics; Female; Gene Expression; Genes, Insect; Longevity / genetics; Male; Ovary / metabolism; RNA Interference; Reproduction / genetics
TL;DR: Identifying evolutionarily conserved genes affecting increased lifespan and delayed reproductive senescence is the first step toward understanding the evolutionary forces that maintain segregating variation at these loci in nature and may provide potential targets for therapeutic intervention to delay senescences while increasing lifespan. (via Semantic Scholar)
Source: Web Of Science
Added: May 8, 2020

2020 journal article

An effective method for evaluation of microplastic contaminant in gastropod from Taihu Lake, China

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 27(18), 22878–22887.

author keywords: Polymer; Microplastics; mu-FT-IR; Gastropod; Digestion
MeSH headings : Animals; China; Environmental Monitoring; Lakes; Microplastics; Plastics; Water Pollutants, Chemical / analysis
TL;DR: A quick method was developed for the isolation and identification of microplastics from gastropod tissues, and the application of the method revealed the presence ofmicroplastics in snails inhabiting Taihu Lake, China. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020

2020 journal article

Frequent template switching in postreplication gaps: suppression of deleterious consequences by the Escherichia coli Uup and RadD proteins

NUCLEIC ACIDS RESEARCH, 48(1), 212–230.

By: Z. Romero*, T. Armstrong*, S. Henrikus*, S. Chen n, D. Glass*, A. Ferrazzoli*, E. Wood*, S. Chitteni-Pattu* ...

MeSH headings : ATP-Binding Cassette Transporters / deficiency; ATP-Binding Cassette Transporters / genetics; Adenosine Triphosphatases / deficiency; Adenosine Triphosphatases / genetics; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Ciprofloxacin / pharmacology; DNA Replication; DNA, Bacterial / genetics; DNA, Bacterial / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Drug Resistance, Bacterial / genetics; Escherichia coli / drug effects; Escherichia coli / genetics; Escherichia coli / metabolism; Escherichia coli Proteins / genetics; Gene Expression Regulation, Bacterial; Genome, Bacterial; Plasmids / chemistry; Plasmids / metabolism; Replication Origin; Sequence Deletion
TL;DR: Uup and RadD are presented as genomic guardians that govern two pathways for resolution of branched DNA intermediates such that potentially deleterious genome rearrangements arising from frequent template switching are averted. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020

2020 journal article

Measurement of 1 alpha hydroxycorticosterone in the Japanese banded houndshark, Triakis scyllium, following exposure to a series of stressors

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 292.

By: A. Iki*, W. Anderson*, C. Deck n, M. Ogihara*, K. Ikeba*, H. Kataoka*, S. Hyodo*

author keywords: 1 alpha-Hydroxycorticosterone; Stress; Elasmobranch; Glucocorticoid
MeSH headings : Animals; Corticosterone / analogs & derivatives; Corticosterone / blood; Elasmobranchii / blood; Environmental Exposure; Fasting / blood; Feeding Behavior; Japan; Male; Time Factors
TL;DR: This is the first report of direct measurement of changes in circulating levels of the primary corticosteroid in elasmobranch fish, 1α-OH-B, following exposure to a stressor such as handling/air-exposure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 27, 2020

2020 journal article

Evolution of an 8‐week upper‐division metagenomics course: Diagramming a learning path from observational to quantitative microbiome analysis

Biochemistry and Molecular Biology Education, 48(4), 391–403.

By: C. Goller n & L. Ott*

MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Computational Biology / methods; Genome, Bacterial; Humans; Metagenomics / education; Metagenomics / methods; Microbiota; Problem-Based Learning / methods; RNA, Bacterial / analysis; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / analysis; RNA, Ribosomal, 16S / genetics; Soil Microbiology; Students
TL;DR: This 8‐week metagenomics laboratory course has the objective of introducing upper‐level undergraduate and graduate students to strategies for designing, executing, and analyzing microbiome investigations and demonstrates that this approach provides an adaptable way to expose students to the cutting‐edge field of meetagenomics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 27, 2020

2020 journal article

Incorporating Nearest-Neighbor Site Dependence into Protein Evolution Models

JOURNAL OF COMPUTATIONAL BIOLOGY, 27(3), 361–375.

By: G. Larson*, J. Thorne n & S. Schmidler*

author keywords: diffusion process; dynamic programming; evolution; phylogeny; protein structure
MeSH headings : Computational Biology / methods; Evolution, Molecular; Models, Statistical; Proteins / chemistry; Proteins / metabolism; Sequence Alignment; Sequence Analysis, Protein; Structural Homology, Protein
TL;DR: This work develops a simple model of site-dependent sequence evolution, which is used to demonstrate the bias resulting from the application of standard site-independent sequence evolution models and yields a significant reduction of bias in estimated evolutionary distances. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: April 20, 2020

2020 journal article

Phthalate Esters and Their Potential Risk in PET Bottled Water Stored under Common Conditions

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 17(1).

author keywords: PET bottles; contained water; PAEs; migration; health risk
MeSH headings : Beijing; Drinking Water / analysis; Endocrine Disruptors / toxicity; Esters / analysis; Esters / toxicity; Phthalic Acids / toxicity; Polyethylene Terephthalates / analysis; Polyethylene Terephthalates / toxicity
TL;DR: The results suggest that a part of the PAEs in PET bottled water originated from plastic bottles, which was related to the storage time and temperature, and Interestingly, DBP mainly contributed to the increased PAEs levels in simulation water. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020

2020 journal article

An empirical evaluation of camera trap study design: How many, how long and when?

METHODS IN ECOLOGY AND EVOLUTION, 11(6), 700–713.

author keywords: camera traps; community ecology; detectability; mammals; relative abundance; species richness; study design; wildlife surveys
TL;DR: It was found that 25–35 camera sites were needed for precise estimates of species richness, depending on scale of the study, and the precision of species‐level estimates of occupancy was highly sensitive to occupancy level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020

2020 journal article

Associations between urine phthalate metabolites and thyroid function in pregnant women and the influence of iodine status

ENVIRONMENT INTERNATIONAL, 137.

By: G. Villanger*, S. Drover*, R. Nethery*, C. Thomsen*, A. Sakhi*, K. Overgaard*, P. Zeiner*, J. Hoppin n ...

author keywords: Phthalates; Thyroid hormones; Pregnancy; Iodine; The Norwegian Mother; Father and Child Cohort study; MoBa
MeSH headings : Child; Cohort Studies; Cross-Sectional Studies; Environmental Exposure; Environmental Pollutants; Female; Humans; Iodine; Norway; Phthalic Acids / toxicity; Phthalic Acids / urine; Pregnancy; Prospective Studies; Thyroid Gland / drug effects; Thyroid Gland / physiopathology
TL;DR: It is found that phthalate exposure is associated with thyroid function in mid-pregnancy among Norwegian women, and that iodine intake, which is essential for thyroid health, could influence some of these relationships. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020

2020 journal article

Context-dependent genetic architecture of Drosophila life span

PLOS BIOLOGY, 18(3).

By: W. Huang n, T. Campbell n, M. Carbone n, W. Jones n, D. Unselt n, R. Anholt n, T. Mackay n

MeSH headings : Animals; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Gene-Environment Interaction; Genetic Variation; Genome-Wide Association Study; Longevity / genetics; Male; RNA Interference; Temperature
TL;DR: The results implicate novel candidate genes affecting life span and suggest that variation for life span may be maintained by variable allelic effects in heterogeneous environments. (via Semantic Scholar)
Source: Web Of Science
Added: April 20, 2020

2020 journal article

Evidence for temperature-dependent shifts in spawning times of anadromous alewife (Alosa pseudoharengus) and blueback herring (Alosa aestivalis)

CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES, 77(4), 741–751.

By: S. Lombardo n, J. Buckel n, E. Hain n, E. Griffith n & H. White

TL;DR: This work analyzed four decades of presence–absence data from a fishery-independent survey to characterize the long-term phenology of river herring (alewife, Alosa pseudoharengus; and blueback herring, Al... (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: April 20, 2020

2020 journal article

Temporal and bidirectional influences of estradiol on voluntary wheel running in adult female and male rats

HORMONES AND BEHAVIOR, 120.

author keywords: Estradiol; Sex differences; Voluntary wheel running; Locomotion; Motivation
MeSH headings : Animals; Behavior, Animal / drug effects; Estradiol / analogs & derivatives; Estradiol / pharmacology; Female; Male; Motivation / drug effects; Motor Activity / drug effects; Rats; Rats, Sprague-Dawley; Running / physiology; Sex Characteristics; Time Factors
TL;DR: Findings indicate that estradiol rapidly, non-rapidly, and bidirectionally modulates wheel running in a sex-responsive manner, and that rapid est radiol action is modulated by non-Rapid Estradiol action. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020

2020 journal article

The howl of Rancho La Brea : Comparative anatomy of modern and fossil canid hyoid bones

Journal of Morphology, 4.

By: D. Flores n, E. Eldridge n, E. Elminowski n, E. Dickinson n & A. Hartstone‐Rose n

author keywords: Canidae; Canis dirus; Canis latrans; functional morphology; vocal apparatus
MeSH headings : Anatomy, Comparative; Animals; California; Fossils; Hyoid Bone / anatomy & histology; Organ Size; Principal Component Analysis; Vocalization, Animal / physiology; Wolves / anatomy & histology
TL;DR: This study compares fossilized hyoid elements from Canis dirus and Canis latrans to samples from modern large congeners, namely: Canis lupus (the gray wolf), Canis rufus ( the red wolf), and modern C. latrans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: ORCID
Added: April 19, 2020

2020 journal article

Gene expression networks in the Drosophila Genetic Reference Panel

GENOME RESEARCH, 30(3), 485–496.

By: L. Everett n, W. Huang n, S. Zhou n, M. Carbone n, R. Lyman n, G. Arya n, M. Geisz n, J. Ma* ...

MeSH headings : Animals; DNA Transposable Elements; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Drosophila melanogaster / microbiology; Female; Gene Expression Regulation; Gene Regulatory Networks; Genetic Variation; High-Throughput Nucleotide Sequencing; Male; Microbiota / genetics; Quantitative Trait Loci; Sequence Analysis, RNA
TL;DR: This study performed deep RNA sequencing of 200 Drosophila Genetic Reference Panel inbred lines with complete genome sequences and mapped expression quantitative trait loci for annotated genes, novel transcribed regions, transposable elements and microbial species, providing new insights regarding the role of natural genetic variation in regulating gene expression. (via Semantic Scholar)
Source: Web Of Science
Added: April 14, 2020

2020 journal article

Systems genetics of the Drosophila metabolome

GENOME RESEARCH, 30(3), 392–405.

By: S. Zhou n, F. Morgante n, M. Geisz n, J. Ma*, R. Anholt n & T. Mackay n

MeSH headings : Animals; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Female; Genetic Association Studies; Genetic Variation; Male; Metabolome / genetics; Phenotype; Quantitative Trait Loci
TL;DR: This work identified sex-specific modules of genetically correlated metabolites and constructed networks that integrate DNA sequence variation and variation in gene expression with variation in metabolites and organismal traits, including starvation stress resistance and male aggression. (via Semantic Scholar)
Source: Web Of Science
Added: April 14, 2020

2020 journal article

Prenatal pesticide exposure and respiratory health outcomes in the first year of life: Results from the infants' Environmental Health (ISA) study

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 225.

By: A. Mora*, J. Hoppin n, L. Cordoba*, J. Cano*, M. Soto-Martinez*, B. Eskenazi*, C. Lindh*, B. Joode*

author keywords: Pesticides; Mancozeb; Respiratory outcomes; Infants; Costa Rica
MeSH headings : Adult; Environmental Pollutants / urine; Ethylenethiourea / metabolism; Female; Humans; Infant; Infant Health; Male; Maneb / urine; Maternal Exposure; Maternal-Fetal Exchange; Pesticides / urine; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Sounds; Respiratory Tract Infections / epidemiology; Young Adult; Zineb / urine
TL;DR: Exposure to mancozeb/ETU during the first half of pregnancy may be associated with respiratory outcomes in the first year of life, and null associations between other pesticide metabolites measured during pregnancy and respiratory outcomes are observed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 14, 2020

2020 journal article

Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells

SMALL, 16(21).

By: J. House n, E. Bouzos*, K. Fahy*, V. Francisco*, D. Lloyd n, F. Wright n, A. Motsinger-Reif*, P. Asuri*, K. Wheeler*

author keywords: nanotoxicity; silver nanoparticles; transcriptomics
MeSH headings : Gene Expression / drug effects; Hepatocytes / drug effects; Humans; Metal Nanoparticles / chemistry; Silver; Surface Properties; Time Factors
TL;DR: Universal to all surface coatings, AgNP-treated cells responded by inactivating proliferation and enabling cell cycle checkpoints, which provide a foundation for understanding hepatic response to low-dose AgNPs for future risk assessment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 14, 2020

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