Works Published in 2016
Displaying works 161 - 180 of 239 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Improving the analytical performance and versatility of paper spray mass spectrometry via paper microfluidics
ANALYST, 141(13), 4065–4073.
TL;DR:
Two paper-based microfluidic techniques, photolithography and wax patterning, were investigated for their potential to improve upon the sensitivity, reproducibility, and versatility of paper spray mass spectrometry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Fluorescent Receptor Binding Assay for Detecting Ciguatoxins in Fish
PLOS ONE, 11(4).
Contributors: D. Hardison*, W. Holland*, J. McCall*, A. Bourdelais*, D. Baden*, H. Darius *, M. Chinain *, P. Tester *
MeSH headings : Animals; Chromatography, Liquid; Ciguatera Poisoning / diagnosis; Ciguatoxins / isolation & purification; Fishes / metabolism; Protein Binding; Rats; Rats, Sprague-Dawley; Synaptosomes / metabolism; Tandem Mass Spectrometry
TL;DR:
A fluorescence based receptor binding assay (RBA(F) was developed to provide an alternative method of screening fish samples for CTXs in facilities not certified to use radioisotopes and is well-suited for routine CTX monitoring programs.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Extremophile Poeciliidae: multivariate insights into the complexity of speciation along replicated ecological gradients
BMC EVOLUTIONARY BIOLOGY, 16.
author keywords: Hydrogen sulfide; Gambusia; Ecological speciation; Life-history evolution; Morphometrics; Poecilia; Reproductive isolation
MeSH headings : Adaptation, Biological; Animals; Biological Evolution; Cyprinodontiformes / metabolism; Cyprinodontiformes / physiology; Ecosystem; Extremophiles / metabolism; Extremophiles / physiology; Female; Gene Flow; Genetic Speciation; Hydrogen Sulfide / metabolism; Male; Multivariate Analysis; Phenotype; Poecilia / metabolism; Poecilia / physiology; Reproductive Isolation; Selection, Genetic
TL;DR:
Progress toward ecological speciation was variable, partially reflecting variation in the strength of divergent selection, highlighting the complexity of selective regimes even in natural systems that are seemingly governed by a single, strong selective agent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials
ARCHIVES OF TOXICOLOGY, 90(7), 1769–1783.
author keywords: Inhalation toxicity; Multi-walled carbon nanotubes; MWCNTs; In vitro testing strategies; Regulatory risk assessment; Pulmonary fibrosis
MeSH headings : Aerosols; Animal Use Alternatives; Animals; Cell Culture Techniques; Cells, Cultured; Equipment Design; Humans; Inhalation Exposure / adverse effects; Lung / cytology; Lung / drug effects; Models, Biological; Nanostructures / administration & dosage; Nanostructures / toxicity; Pulmonary Fibrosis / chemically induced; Toxicity Tests / instrumentation; Toxicity Tests / methods
TL;DR:
The workshop discussions provided the fundamental design components of an air–liquid interface in vitro test system that will be subsequently expanded to the development of an alternative testing strategy to predict pulmonary toxicity and to generate data that will enable effective risk assessment of NMs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 article
Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype
TRANSLATIONAL TOXICOLOGY: DEFINING A NEW THERAPEUTIC DISCIPLINE, pp. 139–169.
author keywords: Cadmium; Lead; Arsenic; Mercury; Epigenetics; DNA methylation; Cancer; Neurodevelopment
TL;DR:
The extent to which heavy-metal-associated epigenetic alterations alter susceptibility to common chronic diseases and how they might be mitigated by some nutrients is discussed, albeit within narrow margins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Can optimal trap mesh size be predicted from body depth in a laterally-compressed fish species?
FISHERIES RESEARCH, 179, 259–270.
author keywords: Black sea bass; Contact selectivity; Bycatch; Trap fishing
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Bioaccumulation Dynamics of Arsenate at the Base of Aquatic Food Webs
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 50(12), 6556–6564.
MeSH headings : Animals; Arsenates; Ecosystem; Food Chain; Fresh Water; Insecta
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Ankylosaurian dinosaur palaeoenvironmental associations were influenced by extirpation, sea-level fluctuation, and geodispersal
Palaeogeography, Palaeoclimatology, Palaeoecology, 449, 289–299.
author keywords: Cretaceous; Western Interior Basin; Ankylosauria; Ankylosauridae; Nodosauridae; Dinosauria
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Analysis of maternal polymorphisms in arsenic (+3 oxidation state)-methyltransferase AS3MT and fetal sex in relation to arsenic metabolism and infant birth outcomes: Implications for risk analysis
REPRODUCTIVE TOXICOLOGY, 61, 28–38.
author keywords: AS3MT; Arsenic; Genotype; Prenatal exposure; Birth outcomes
MeSH headings : Adolescent; Adult; Arsenic / metabolism; Arsenic / urine; Female; Genotype; Humans; Infant, Newborn; Male; Methyltransferases / genetics; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Outcome; Risk Assessment; Sex Factors; Young Adult
TL;DR:
Assessment of relationships between single nucleotide polymorphisms in AS3MT and urinary concentrations of iAs and its methylated metabolites in pregnant women and infants highlighted a potential sex-dependence of the relationships among maternal genotype, iAs metabolism and infant health outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies
Pharmacogenetics and Genomics, 26(7), 324–333.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Validation of a mathematical model for green algae (Raphidocelis Subcapitata) growth and implications for a coupled dynamical system with Daphnia magna
Applied Sciences-Basel, 6(5).
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus
JOURNAL OF CELL SCIENCE, 129(9), 1855–1865.
author keywords: TAK1; Endoplasmic reticulum stress; Leptin; Hypothalamus; Obesity
MeSH headings : Animals; Dietary Fats / adverse effects; Dietary Fats / pharmacology; Endoplasmic Reticulum Stress; Hyperphagia / chemically induced; Hyperphagia / genetics; Hyperphagia / metabolism; Hyperphagia / pathology; Hypothalamus / metabolism; Hypothalamus / pathology; Leptin / genetics; Leptin / metabolism; MAP Kinase Kinase Kinases / genetics; MAP Kinase Kinase Kinases / metabolism; Mice; Mice, Knockout; Obesity / chemically induced; Obesity / genetics; Obesity / metabolism; Obesity / pathology; Sterol Regulatory Element Binding Proteins / genetics; Sterol Regulatory Element Binding Proteins / metabolism
TL;DR:
It is found that deletion of Tak1 increased ER volume and facilitated ER-stress tolerance in cultured cells, which was mediated by upregulation of sterol-regulatory-element-binding protein (SREBP)-dependent lipogenesis and central nervous system (CNS) deletion upregulated SREBP-target lipogenic genes and blocked ER stress in the hypothalamus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Peptide sequences from the first Castoroides ohioensis skull and the utility of old museum collections for palaeoproteomics
author keywords: collagen I; palaeoproteomics; museum specimens; nasal turbinates; palaeoproteomics
MeSH headings : Animals; Fossils; Museums; Peptides / chemistry; Phylogeny; Proteomics; Rodentia / classification; Skull
TL;DR:
This study illustrates the utility of archived museum specimens for both the recovery of preserved proteins and phylogenetic analyses with characterize proteins from the nasal turbinates of the first Castoroides ohioensis skull ever discovered.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
PCR amplification of a multi-copy mitochondrial gene (cox3) improves detection of Cytauxzoon felis infection as compared to a ribosomal gene (18S)
VETERINARY PARASITOLOGY, 225, 123–130.
author keywords: Cytauxzoonosis; Cytochrome c oxidase; Piroplasmosis; Mitochondria; Feline; Molecular diagnostic assays
MeSH headings : Animals; Cat Diseases / diagnosis; Cats; DNA, Protozoan / blood; DNA, Protozoan / genetics; Electron Transport Complex IV / genetics; Gene Dosage; Haemosporida / genetics; Polymerase Chain Reaction / standards; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / diagnosis; RNA, Ribosomal, 18S / genetics; Sensitivity and Specificity
TL;DR:
A PCR assay targeting the C. felis mitochondrial gene cytochrome c oxidase subunit III (cox3) is designed and demonstrated that the cox3 PCR can detect as low as 1 copy of DNA target and can detect C.Felis during early infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study
Clinical Epigenetics, 8.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Neutron protein crystallography: A complementary tool for locating hydrogens in proteins
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 602, 48–60.
author keywords: Neutron; Crystallography; Hydrogen; Enzyme; Protonation; Water
TL;DR:
Methods to produce isotopically-substituted proteins and to grow large crystals are provided in the context of neutron structures reported in the literature along with technique-specific strategies including joint X-ray/neutron structure refinement.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Natural variability in Drosophila larval and pupal NaCl tolerance
JOURNAL OF INSECT PHYSIOLOGY, 88, 15–23.
author keywords: QTL; NaCl; Natural variation; Drosophila melanogaster; Pupation position
MeSH headings : Animals; Culture Media; Drosophila melanogaster / genetics; Drosophila melanogaster / growth & development; Larva / genetics; Larva / growth & development; Pupa / genetics; Pupa / growth & development; Quantitative Trait Loci / genetics; Salt Tolerance / genetics; Salt Tolerance / physiology
TL;DR:
This work describes four D. melanogaster lines that were selected for different degrees of NaCl tolerance, and present data on their survival, development, and pupation position when raised on varying NaCl concentrations, and presents the results of Quantitative Trait Loci mapping of natural variation in larval and pupal NaClolerance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Keratin Durability Has Implications for the Fossil Record: Results from a 10 Year Feather Degradation Experiment
PLOS ONE, 11(7), e0157699.
Ed(s): B. Beatty
MeSH headings : Animals; Antibodies / chemistry; Biological Evolution; Chickens; Epidermis / anatomy & histology; Feathers / chemistry; Fossils; Humans; Keratins / chemistry; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nails; Phylogeny; Temperature
TL;DR:
It is shown that feather keratin is durable, demonstrates structural and microstructural integrity, and retains epitopes suitable for specific antibody recognition in even the harshest conditions, which support the hypothesis that keratin antibody reactivity can be used to identify the nature and composition of epidermal structures in the rock record.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2016 journal article
Infertility and recurrent miscarriage with complex II deficiency-dependent mitochondrial oxidative stress in animal models
Mechanisms of Ageing and Development, 155, 22–35.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Grouping substitution types into different relaxed molecular clocks
Source: NC State University Libraries
Added: August 6, 2018
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