Works Published in 2011
Displaying works 121 - 127 of 127 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
Unexpected Reduction of Skin Tumorigenesis on Expression of Cyclin-Dependent Kinase 6 in Mouse Epidermis
AMERICAN JOURNAL OF PATHOLOGY, 178(1), 345–354.
MeSH headings : Animals; Cell Proliferation; Cell Transformation, Neoplastic / genetics; Cell Transformation, Neoplastic / metabolism; Cell Transformation, Neoplastic / pathology; Cyclin-Dependent Kinase 4 / biosynthesis; Cyclin-Dependent Kinase 4 / genetics; Cyclin-Dependent Kinase 6 / biosynthesis; Cyclin-Dependent Kinase 6 / genetics; Epidermis / enzymology; Epidermis / pathology; Hyperplasia / enzymology; Keratin-5 / genetics; Keratinocytes / enzymology; Keratinocytes / pathology; Mice; Mice, Transgenic; Promoter Regions, Genetic; Skin Neoplasms / enzymology; Skin Neoplasms / genetics; Skin Neoplasms / metabolism
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Heterotaxin: A TGF-beta Signaling Inhibitor Identified in a Multi-Phenotype Profiling Screen in Xenopus Embryos
CHEMISTRY & BIOLOGY, 18(2), 252–263.
MeSH headings : Animals; Cell Line; Drug Evaluation, Preclinical; Embryo, Nonmammalian / abnormalities; Embryo, Nonmammalian / cytology; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / metabolism; Humans; Intracellular Space / drug effects; Intracellular Space / metabolism; Neovascularization, Physiologic / drug effects; Phenotype; Pyridines / chemistry; Pyridines / pharmacology; Signal Transduction / drug effects; Stereoisomerism; Structure-Activity Relationship; Transforming Growth Factor beta / metabolism; Xenopus laevis
TL;DR:
A small molecule screen for left-right asymmetry phenotypes in Xenopus embryos is performed and a pyridine analog, heterotaxin, is discovered, which disrupts both cardiovascular and digestive organ laterality and inhibits TGF-β-dependent left- right asymmetric gene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Efficacy of Oral Famotidine and 2 Omeprazole Formulations for the Control of Intragastric pH in Dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(1), 47–54.
author keywords: Acid disorders; Gastroenterology; Gastrointestinal
MeSH headings : Administration, Oral; Animals; Anti-Ulcer Agents / administration & dosage; Anti-Ulcer Agents / pharmacology; Cross-Over Studies; Dogs / metabolism; Famotidine / administration & dosage; Famotidine / pharmacology; Female; Gastric Acidity Determination / veterinary; Gastric Mucosa / metabolism; Hydrogen-Ion Concentration / drug effects; Male; Omeprazole / administration & dosage; Omeprazole / pharmacology; Stomach / drug effects; Telemetry / veterinary
TL;DR:
Oral omeprazole tablet and RP provide superior gastric acid suppression to famotidine, and should therefore be considered more effective for the treatment of acid related disorders in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Effects of Clopidogrel and Aspirin on Platelet Aggregation, Thromboxane Production, and Serotonin Secretion in Horses
JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(1), 116–122.
author keywords: Antiplatelet agents; Laminitis; SR 26334; Thrombosis
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Area Under Curve; Aspirin / pharmacokinetics; Aspirin / pharmacology; Blood Platelets / drug effects; Blood Platelets / physiology; Clopidogrel; Cross-Over Studies; Female; Horses / blood; Horses / physiology; Male; Platelet Activation / drug effects; Platelet Aggregation Inhibitors / pharmacology; Platelet Count / veterinary; Prospective Studies; Random Allocation; Serotonin / blood; Thrombosis / prevention & control; Thrombosis / veterinary; Thromboxane B2 / biosynthesis; Thromboxane B2 / blood; Ticlopidine / analogs & derivatives; Ticlopidine / pharmacokinetics; Ticlopidine / pharmacology
TL;DR:
Clopidogrel effectively decreases ADP-induced platelet aggregation in horses, and could have therapeutic applications for equine diseases associated with platelet activation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Autocrine Effects of Interleukin-6 Mediate Acute-Phase Proinflammatory and Tissue-Reparative Transcriptional Responses of Canine Bladder Mucosa
INFECTION AND IMMUNITY, 79(2), 708–715.
MeSH headings : Acute-Phase Reaction / metabolism; Animals; Dogs; Humans; Interleukin-6 / metabolism; Mucous Membrane / metabolism; Mucous Membrane / microbiology; Signal Transduction; Tissue Culture Techniques; Urinary Bladder / metabolism; Urinary Bladder / microbiology; Uropathogenic Escherichia coli; Urothelium / metabolism
TL;DR:
It is demonstrated that uropathogenic Escherichia coli infection stimulates the synthesis of IL-6 by all urothelial cell layers, with the u rothelial cells alone representing the only site of unequivocal IL- 6 receptor expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Aqueous humor and plasma concentrations of a compounded 0.2% solution of terbinafine following topical ocular administration to normal equine eyes
VETERINARY OPHTHALMOLOGY, 14(1), 41–47.
author keywords: aqueous humor; equine; keratomycosis; terbinafine
MeSH headings : Absorption; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / analysis; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Aqueous Humor / chemistry; Chromatography, High Pressure Liquid / veterinary; Cornea / metabolism; Female; Horses / metabolism; Male; Naphthalenes / administration & dosage; Naphthalenes / analysis; Naphthalenes / blood; Naphthalenes / pharmacokinetics; Ophthalmic Solutions; Terbinafine
TL;DR:
Topical ocular administration of compounded 0.2% terbinafine solution does not result in detectable AH or plasma levels following administration to normal equine eyes, suggesting its use for deep corneal or intraocular fungal infections in equine ophthalmology may be limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Partial Regulatory T Cell Depletion Prior to Acute Feline Immunodeficiency Virus Infection Does Not Alter Disease Pathogenesis
PLOS ONE, 6(2).
MeSH headings : Acute Disease; Acute-Phase Reaction / immunology; Animals; Antibodies, Monoclonal / administration & dosage; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / pathology; Cat Diseases / immunology; Cat Diseases / virology; Cats; Disease Progression; Down-Regulation / immunology; Feline Acquired Immunodeficiency Syndrome / etiology; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / pathology; Feline Acquired Immunodeficiency Syndrome / virology; Female; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / physiology; Interleukin-2 Receptor alpha Subunit / immunology; Lymphocyte Count; Lymphocyte Depletion / methods; Lymphocyte Depletion / veterinary; Specific Pathogen-Free Organisms; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / pathology; Viremia / veterinary
TL;DR:
It is reported here that partial Treg cell depletion prior to FIV infection does not significantly change provirus, viremia, or CD4+ T cell levels in blood and lymphoid tissues during the acute phase of disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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