Works Published in 2018
Displaying works 161 - 174 of 174 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
HT-eQTL: integrative expression quantitative trait loci analysis in a large number of human tissues
BMC Bioinformatics, 19.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
Genetic analysis of Southern Brazil subjects using the PowerSeq (TM) AUTO/Y system for short tandem repeat sequencing
FORENSIC SCIENCE INTERNATIONAL-GENETICS, 33, 129–135.
author keywords: Short tandem repeat; PowerSeq (TM) AUTO/Y system; South Brazil; Sequence variation
MeSH headings : Brazil; Chromosomes, Human, Y; DNA Fingerprinting; Female; Gene Frequency; Genetic Variation; Genetics, Population; High-Throughput Nucleotide Sequencing; Humans; Male; Microsatellite Repeats; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR:
The results obtained in this study demonstrate the importance of genetic analysis based on sequencing and highlight the diversity of the South Brazilian population when characterized by STR sequencing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Development and assessment of fully automated and globally transitive geometric morphometric methods, with application to a biological comparative dataset with high interspecific variation
Anatomical Record (Hoboken, N.J. : 2007), 301(4), 636–658.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
Concise Review: Is Cardiac Cell Therapy Dead? Embarrassing Trial Outcomes and New Directions for the Future
Stem Cells Translational Medicine, 7(4), 354–359.
author keywords: Myocardial injury; Stem cell therapy; Synthetic stem cells; Biomaterials
MeSH headings : Animals; Cell- and Tissue-Based Therapy / methods; Heart / physiology; Heart Diseases / therapy; Humans; Regeneration / physiology; Stem Cell Transplantation / methods; Stem Cells / cytology
TL;DR:
This concise review provides a brief introduction into stem cell therapies for ischemic heart disease, and summarizes cell‐based and cell‐free paradigms, their limitations, and the benefits of using them to target disease.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2018 article
Resolving single-actin filaments within the contractile ring of fission yeast
Laplante, C. (2018, February 13). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 115, pp. 1403–1405.
MeSH headings : Actin Cytoskeleton; Actins; Cytokinesis; Schizosaccharomyces; Schizosaccharomyces pombe Proteins
TL;DR:
There are still many aspects of the general mechanisms of contractile ring assembly, constriction, and disassembly that the authors do not understand and one remaining enigma about cytokinesis is the how the network of actin filaments is structured during constriction.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2018 article
Olfactory toxicity in rats following manganese chloride nasal instillation: A pilot study
Foster, M. L., Rao, D. B., Francher, T., Traver, S., & Dorman, D. C. (2018, January). NEUROTOXICOLOGY, Vol. 64, pp. 284–290.
author keywords: Manganese; Olfactory toxicity; Olfactory discrimination; Pharmacokinetics
MeSH headings : Administration, Inhalation; Animals; Chlorides / administration & dosage; Chlorides / metabolism; Chlorides / toxicity; Discrimination, Psychological / drug effects; Male; Manganese Compounds / administration & dosage; Manganese Compounds / metabolism; Odorants; Olfactory Bulb / drug effects; Olfactory Bulb / metabolism; Olfactory Bulb / pathology; Olfactory Mucosa / drug effects; Olfactory Mucosa / metabolism; Olfactory Mucosa / pathology; Pilot Projects; Rats, Inbred F344
TL;DR:
The nasal instillation and OD procedures developed in this study are useful methods to assess manganese – induced olfactory deficits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 article
Neonatal C57BL/6J and parkin mice respond differently following developmental manganese exposure: Result of a high dose pilot study
Foster, M. L., Bartnikas, T. B., Maresca-Fichter, H. C., Mercadante, C., Dash, M., Miller, C., & Dorman, D. C. (2018, January). NEUROTOXICOLOGY, Vol. 64, pp. 291–299.
author keywords: Manganese; Neurotoxicity; Pharmacokinetics; Metabolism
MeSH headings : Animals; Animals, Newborn; Brain / drug effects; Brain / metabolism; Female; Liver / drug effects; Liver / metabolism; Male; Manganese / toxicity; Mice, Inbred C57BL; Mice, Knockout; Motor Activity / drug effects; Pilot Projects; Tissue Distribution; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism
TL;DR:
The results suggest that the Parkin gene defect did not increase the susceptibility of neonatal mice to adverse health effects associated with high‐dose Mn exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Lymphocyte Subsets in the Adrenal Glands of Dogs With Primary Hypoadrenocorticism
VETERINARY PATHOLOGY, 55(1), 177–181.
author keywords: Addison's disease; hypoadrenocorticism; endocrine diseases; adrenal gland; immunophenotype; lymphocyte subsets; dogs
MeSH headings : Addison Disease / pathology; Addison Disease / veterinary; Adrenal Glands / pathology; Animals; CD4 Lymphocyte Count / veterinary; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; In Situ Hybridization / veterinary; Lymphocyte Subsets / pathology; Male
TL;DR:
It is shown that the lymphocytes are primarily CD4+ rather than CD8+.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Impact of synthetic canine cerumen on in vitro penetration of auricular skin of dogs by florfenicol, terbinafine, and betamethasone acetate
AMERICAN JOURNAL OF VETERINARY RESEARCH, 79(3), 333–341.
MeSH headings : Administration, Cutaneous; Animals; Betamethasone / pharmacokinetics; Cerumen / chemistry; Chromatography, High Pressure Liquid / veterinary; Dogs / metabolism; Female; Gels; Male; Naphthalenes / pharmacokinetics; Skin / drug effects; Skin / metabolism; Skin Absorption / drug effects; Terbinafine; Thiamphenicol / analogs & derivatives; Thiamphenicol / pharmacokinetics
TL;DR:
3H-betamethasone acetate, 14C-terbinafine hydrochloride, and florfenicol were all absorbed in vitro through healthy auricular skin specimens within the first 24 hours after topical application, and synthetic canine cerumen had no impact on dermal absorption in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Advanced three-dimensional culture of equine intestinal epithelial stem cells
EQUINE VETERINARY JOURNAL, 50(2), 241–248.
author keywords: horse; stem cell; 3D culture; intestine; enteroid; organoid
MeSH headings : Animals; Cell Culture Techniques / veterinary; Cell Differentiation; Female; Horses; Intestinal Mucosa / cytology; Male; Models, Biological; Stem Cells / physiology
TL;DR:
The successful culture of equine intestinal crypts into 3D "mini-guts" allows for in vitro studies of the equine intestine and has relevance to future development of novel therapies that harness the regenerative potential ofequine intestine in horses with gastrointestinal disease (colic).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
What is your diagnosis?
Journal of the American Veterinary Medical Association, 252(2), 173–175.
MeSH headings : Animals; Chickens; Diagnosis, Differential; Female; Hindlimb; Kidney Neoplasms / complications; Kidney Neoplasms / diagnostic imaging; Kidney Neoplasms / pathology; Kidney Neoplasms / veterinary; Lameness, Animal / diagnosis; Lameness, Animal / diagnostic imaging; Lameness, Animal / etiology; Marek Disease / complications; Marek Disease / diagnosis; Marek Disease / pathology; Muscular Atrophy / complications; Muscular Atrophy / diagnostic imaging; Muscular Atrophy / veterinary; Poultry Diseases / diagnosis; Poultry Diseases / diagnostic imaging; Poultry Diseases / etiology; Poultry Diseases / pathology; Radiography / veterinary; Sciatic Nerve / pathology; Ultrasonography / veterinary
TL;DR:
On clinical examination, the dog was bright, alert and responsive with a body weight of 17.2kg and a body condition score of 5/9 and the mucous membranes were pink and moist, with a capillary refill time of one second.
(via Semantic Scholar)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2018 journal article
Comparison of absorption characteristics of oral reference and compounded itraconazole formulations in healthy cats
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 252(2), 195–200.
MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / chemistry; Antifungal Agents / pharmacokinetics; Area Under Curve; Cats / blood; Cross-Over Studies; Dosage Forms; Half-Life; Itraconazole / administration & dosage; Itraconazole / chemistry; Itraconazole / pharmacokinetics; Random Allocation; Therapeutic Equivalency
TL;DR:
Compounded oral formulations of itraconazole should not be used for cats because of poor absorption and the differences in absorption between the 2 reference formulations suggested that doses required to meet human target serum concentrations in cats are markedly different.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2018 journal article
The computed tomographic "tree-in-bud" pattern: Characterization and comparison with radiographic and clinical findings in 36 cats
VETERINARY RADIOLOGY & ULTRASOUND, 59(1), 32–42.
author keywords: bronchi; feline; mucus; nodule; plug
MeSH headings : Animals; Bronchial Diseases / diagnosis; Bronchial Diseases / diagnostic imaging; Bronchial Diseases / pathology; Bronchial Diseases / veterinary; Cat Diseases / diagnosis; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Diagnosis, Differential; Female; Male; Missouri; North Carolina; Quebec; Retrospective Studies; Tomography, X-Ray Computed / veterinary
TL;DR:
The "tree-in-bud" pattern should be considered as a differential diagnosis for radiographic soft tissue opaque nodules in feline lungs, based on lesion localization and presence or suspicion of a concomitant bronchial disease for cats in this sample.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Comparisons between elastographic stiffness scores for benign versus malignant lymph nodes in dogs and cats
VETERINARY RADIOLOGY & ULTRASOUND, 59(1), 79–88.
author keywords: elastography; lymph node; ultrasound
MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cats; Cross-Sectional Studies; Dog Diseases / diagnostic imaging; Dogs; Elasticity Imaging Techniques / methods; Elasticity Imaging Techniques / veterinary; Female; Lymph Nodes / diagnostic imaging; Lymphoma / diagnostic imaging; Lymphoma / veterinary; Male; Prospective Studies
TL;DR:
Findings indicated that elastographic stiffness scores differed between benign and malignant lymph node groups; however overlapping scores for the two groups limited the use of this technique for routine clinical diagnosis of malignancy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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