Works Published in 2019
Displaying works 201 - 220 of 227 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
The miRNA-targeted transcriptome of porcine alveolar macrophages upon infection with Porcine Reproductive and Respiratory Syndrome Virus
Scientific Reports, 9(1).
MeSH headings : Animals; Gene Expression Regulation / genetics; Macrophages, Alveolar / metabolism; Macrophages, Alveolar / pathology; MicroRNAs / genetics; MicroRNAs / isolation & purification; Oligonucleotide Array Sequence Analysis; Porcine Reproductive and Respiratory Syndrome / genetics; Porcine Reproductive and Respiratory Syndrome / pathology; Porcine Reproductive and Respiratory Syndrome / virology; Porcine respiratory and reproductive syndrome virus / genetics; Porcine respiratory and reproductive syndrome virus / pathogenicity; Signal Transduction / genetics; Swine; Transcriptome / genetics
TL;DR:
It is indicated that the miRNome expressed by steady-state PAMs reacts promptly to counterbalance PRRSV infection by a pervasive modulation of host functions.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: March 11, 2019
2019 journal article
Virus discovery reveals frequent infection by diverse novel members of the Flaviviridae in wild lemurs
ARCHIVES OF VIROLOGY, 164(2), 509–522.
MeSH headings : Animals; Flaviviridae / classification; Flaviviridae / genetics; Flaviviridae / isolation & purification; Flaviviridae / physiology; Flaviviridae Infections / veterinary; Flaviviridae Infections / virology; Genetic Variation; Lemur / virology; Madagascar; Phylogeny; Primate Diseases / virology
TL;DR:
The results support the current proposed model of virus-host co-divergence with frequent occurrence of cross-species transmission for these genera and highlight how the discovery of more members of the Flaviviridae can help clarify the ecology and evolutionary history of these viruses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: March 4, 2019
2019 journal article
Serum Metabolomics Identifies Altered Bioenergetics, Signaling Cascades in Parallel with Exposome Markers in Crohn's Disease
MOLECULES, 24(3).
author keywords: Inflammatory Bowel Disease; Crohn's Disease; Serum Metabolomics; docosahexaenoic acid; Tryptophan Metabolism; ergothioneine; gut microbiota; Exposome
MeSH headings : Amino Acids / metabolism; Biomarkers; Crohn Disease / blood; Crohn Disease / metabolism; Energy Metabolism; Fatty Acids / metabolism; Humans; Lipid Metabolism; Metabolome; Metabolomics; Oxidation-Reduction; Signal Transduction
TL;DR:
This study endorses the analytical capacity of untargeted metabolomics for biomarker development, cohort stratification, and mechanistic interpretation in IBD, and the findings might be valuable for advancing biomarker research and etiologic inquiry in Crohn’s disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 4, 2019
2019 journal article
Prevalence and distribution of feet lesions in dairy cows raised in the freestall
SEMINA-CIENCIAS AGRARIAS, 40(1), 239–247.
Contributors: R. Ebling *, A. Krummenauer*, G. Machado* , L. Carazzo* & M. Do Rêgo Leal*
author keywords: Bovine; Foot; Preventive hoof trimming; Lameness
TL;DR:
The results show that dairy cows raised in a free stall system have a high prevalence of claudication and foot diseases and these data should be taken into account when altering the livestock management of these animals in order to reduce significant economic losses in the herd.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 4, 2019
2019 journal article
Computed Tomography of Lobular Dissecting Hepatitis in a Young Golden Retriever
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 55(2).
MeSH headings : Aging; Amoxicillin / therapeutic use; Animal Feed / analysis; Animals; Anti-Bacterial Agents / therapeutic use; Dietary Proteins / administration & dosage; Dog Diseases / diagnostic imaging; Dog Diseases / etiology; Dog Diseases / pathology; Dog Diseases / therapy; Dogs; Female; Gastrointestinal Agents / therapeutic use; Hepatic Encephalopathy / drug therapy; Hepatic Encephalopathy / etiology; Hepatic Encephalopathy / veterinary; Hepatitis, Animal / complications; Hepatitis, Animal / diagnostic imaging; Hepatitis, Animal / pathology; Hepatitis, Animal / therapy; Lactulose / therapeutic use; Liver / diagnostic imaging; Liver / pathology; Omeprazole / therapeutic use; Tomography, X-Ray Computed / veterinary
TL;DR:
Histologic evaluation of percutaneous needle biopsy samples of a liver nodule showed a rare form of hepatitis called lobular dissecting hepatitis, which should be considered as a differential in young dogs with precontrast hyperattenuating hepatic nodules on noncontrast-enhanced computed tomography.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 4, 2019
2019 journal article
A One Health Approach to Investigating <i>Leptospira</i> Serogroups and Their Spatial Distributions among Humans and Animals in Rio Grande do Sul, Brazil, 2013–2015
Tropical Medicine and Infectious Disease, 4(1).
Contributors: N. Polo *, G. Machado n , R. Rodrigues *, P. Hamrick*, C. Munoz-Zanzi *, M. Pereira *, M. Bercini*, L. Timm *, M. Schneider *
author keywords: leptospirosis; serogroups; One Health; zoonoses; global health; infectious disease; Brazil
TL;DR:
Identifying and mapping the serogroups circulating using the One Health approach is the first step for further understanding the distribution of the disease in the state of Rio Grande do Sul, and has the potential to aid in guiding public health and agricultural practices.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: March 4, 2019
2019 article
Spatial distribution and spread potential of sixteen Leptospira serovars in a subtropical region of Brazil
Jara, M., Escobar, L. E., Rodriges, R. O., Frias, A., Sanhueza, J., & Machado, G. (2019, February 28). BioRxiv, Vol. 2.
Contributors: M. Jara n, L. Escobar *, R. Rodriges, A. Frias n, J. Sanhueza * & G. Machado n
TL;DR:
An ecological niche modeling framework was used to characterize and compare Leptospira serovars in both geographical and environmental space and found ecological divergence among their occupied ecological niches, being Sejroe the most asymmetric.
(via Semantic Scholar)
Source: ORCID
Added: March 1, 2019
2019 journal article
Consistent and correctable bias in metagenomic sequencing measurements
BioRxiv, 2, 559831.
Source: ORCID
Added: February 26, 2019
2019 journal article
Metapopulation Model from Pathogen's Perspective: A Versatile Framework to Quantify Pathogen Transfer and Circulation between Environment and Hosts
SCIENTIFIC REPORTS, 9.
MeSH headings : Algorithms; Cross Infection / prevention & control; Cross Infection / transmission; Disinfection; Host-Pathogen Interactions; Humans; Models, Biological; Population Dynamics
TL;DR:
It is demonstrated that metapopulation models serve as an ideal modeling framework to characterize and quantify pathogen transfer between environment and hosts and unifies host, pathogen, and environment, collectively known as the epidemiological triad, a fundamental concept in epidemiology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 25, 2019
2019 journal article
Staphylococci in dairy goats and human milkers, and the relationship with herd management practices
SMALL RUMINANT RESEARCH, 171, 13–22.
author keywords: Staphylococcus aureus; Coagulase negative staphylococci; Unpasteurized milk; Mastitis; Dairy goats; Herd management
TL;DR:
A wide range of milking routines was found, and gloves were not commonly worn by milkers (only 10% of farms milkers always wore gloves), the most common use of milk was home consumption and 28 of the 30 goat dairies reported the consumption of unpasteurized milk.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 25, 2019
2019 book
Food safety in Poultry meat production
(1st ed.). Springer US.
Source: NC State University Libraries
Added: February 21, 2019
2019 journal article
The Mandate for a Global “One Health” Approach to Antimicrobial Resistance Surveillance
The American Journal of Tropical Medicine and Hygiene, 1.
MeSH headings : Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial / drug effects; Ecuador; Escherichia coli / drug effects; Global Health; Poultry; Prevalence; Weights and Measures; beta-Lactamases
TL;DR:
The researchers investigated the prevalence of CTX-M extended-spectrum beta-lactamases in chickens from small-scale poultry farms and in children living on the farms in rural Ecuador, and reported a shared evolutionary history between chicken and human samples.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 18, 2019
2019 journal article
Phenotypic and Genotypic Characterization of Escherichia coli and Salmonella enterica from Dairy Cattle Farms in the Wakiso District, Uganda: A Cross-Sectional Study
Foodborne Pathogens and Disease, 16(1), 54–59.
author keywords: antimicrobial resistance; ESBL; E; coli; Salmonella enterica; Uganda
MeSH headings : Animals; Anti-Infective Agents / pharmacology; Cattle; Cross-Sectional Studies; Dairying; Drug Resistance, Multiple, Bacterial; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / isolation & purification; Escherichia coli Infections / epidemiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / veterinary; Farms; Feces / microbiology; Female; Pilot Projects; Plasmids / genetics; Quinolones / pharmacology; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Salmonella enterica / enzymology; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Uganda / epidemiology; beta-Lactamases / genetics
TL;DR:
It is concluded that the presence of globally disseminated E. coli carrying blaCTX-M-15 and bla CTX- M-27 warrants further study to prevent further spread, and can be used as a baseline for implementation of a more robust national integrated surveillance system throughout Uganda.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 18, 2019
2019 journal article
Pasteurella canis infective endocarditis in a dog
VETERINARY MICROBIOLOGY, 229, 14–19.
author keywords: Pasteurella cards; Infective vegetative endocarditis; Sepsis; Vasculitis; 16S rDNA PCR; MAIDLTOF
MeSH headings : Animals; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / microbiology; Fatal Outcome; Male; Pasteurella / classification; Pasteurella Infections / microbiology; Pasteurella Infections / veterinary
TL;DR:
The goal of this study is to detail the clinical presentation and microbiological findings associated with a novel causative agent of infective endocarditis in the dog.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: February 18, 2019
2019 journal article
Association of plasma haptoglobin concentration and other biomarkers with bovine respiratory disease status in pre-weaned dairy calves
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 31(1), 40–46.
author keywords: Bovine respiratory disease; calves; haptoglobin; plasma bactericide
MeSH headings : Animals; Biomarkers / blood; Bovine Respiratory Disease Complex / diagnosis; Bovine Respiratory Disease Complex / immunology; California; Case-Control Studies; Cattle; Dairying; Female; Haptoglobins / metabolism; Immunity, Humoral; Male
TL;DR:
The area under the curve (AUC) for Hp was 0.68, a value greater than those for PB or the remaining CBC parameters, indicating that Hp may be the most useful biomarker of BRD in pre-weaned dairy calves.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: February 11, 2019
2019 journal article
Reevaluation of Hepatocellular Neoplasms in CD-1 Mice from a 2-year Oral Carcinogenicity Study with Permethrin
TOXICOLOGIC PATHOLOGY, 47(1), 11–17.
author keywords: permethrin; liver neoplasms; hepatocellular adenoma; hepatocellular carcinoma; Pathology Working Group
MeSH headings : Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens / toxicity; Dose-Response Relationship, Drug; Female; Liver Neoplasms / chemically induced; Liver Neoplasms / pathology; Liver Neoplasms, Experimental / chemically induced; Liver Neoplasms, Experimental / pathology; Male; Mice, Inbred Strains; Permethrin / toxicity; Sex Factors
TL;DR:
An expert panel of pathologists was convened as a Pathology Working Group (PWG) to review coded liver histology sections from male and female mice and to classify all liver neoplasms according to current nomenclature and diagnostic criteria guidelines, which indicate that permethrin induced a significant dose-dependent increase in the incidence of hepatocellular neoplasm in treated female mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: February 11, 2019
2019 journal article
Gut microbiome disruption altered the biotransformation and liver toxicity of arsenic in mice
ARCHIVES OF TOXICOLOGY, 93(1), 25–35.
author keywords: Gut bacteria; Microbiome; Arsenic biotransformation; Methylation; One-carbon metabolism
MeSH headings : Animals; Arsenic / metabolism; Arsenic / toxicity; Arsenites; Dysbiosis / physiopathology; Female; Gastrointestinal Microbiome; Inactivation, Metabolic; Liver / metabolism; Mice, Inbred C57BL; Signal Transduction; Sodium Compounds; Tumor Suppressor Protein p53
TL;DR:
Investigation of the role of the gut microbiota in As biotransformation and its toxicity in mice found that the urinary total As levels of GM-disrupted mice were much higher, but the fecaltotal As levels were lower, than the levels in the conventionally raised mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: February 11, 2019
2019 journal article
Allantoic Metabolites, Progesterone, and Estradiol-17 beta Remain Unchanged After Infection in an Experimental Model of Equine Ascending Placentitis
JOURNAL OF EQUINE VETERINARY SCIENCE, 73, 95–105.
author keywords: Equine; Ascending placentitis; Metabolomics; Allantoic fluid
TL;DR:
The results of this study established a database of equine allantoic fluid metabolites and confirmed the utility of uteroplacental ultrasound for detection of placentitis before the onset of hematologic changes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 11, 2019
2019 journal article
Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury
ADVANCED FUNCTIONAL MATERIALS, 29(4).
author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
TL;DR:
A platelet‐inspired nanocell (PINC) that incorporates both prostaglandin E2 (PGE2)‐modified platelet membrane and cardiac stromal cell‐secreted factors to target the heart after I/R injury is introduced, which represents a promising therapeutic delivery platform for treating myocardial ischemia/reperfusion injury.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: February 4, 2019
2019 article
Mapping changes in the spatiotemporal distribution of lumpy skin disease virus
Machado, G., Korennoy, F., Alvarez, J., Picasso-Risso, C., Perez, A., & VanderWaal, K. (2019, February 1). BioRxiv, Vol. 2.
Contributors: G. Machado n , F. Korennoy *, J. Alvarez *, C. Picasso-Risso *, A. Perez * & K. VanderWaal *
TL;DR:
Understanding of the ecological requirements of LSDV in temperate regions is advanced and may help in the design and implementation of prevention and surveillance strategies in the region.
(via Semantic Scholar)
Source: ORCID
Added: February 2, 2019
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