Center for Human Health and the Environment

Works Published in 2018

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Displaying works 221 - 240 of 302 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

Signal transducer and activator of transcription 1 regulates multiwalled carbon nanotube-induced pulmonary fibrosis in mice via suppression of transforming growth factor-beta 1 production and signaling

Annals of the American Thoracic Society, 15, S129–130.

By: K. Duke, A. Taylor, M. Ihrie, K. Shipkowski, E. Needham & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2018 review

Sex Differences in Medium Spiny neuron excitability and Glutamatergic Synaptic input: Heterogeneity Across Striatal Regions and evidence for Estradiol-Dependent Sexual Differentiation

[Review of ]. FRONTIERS IN ENDOCRINOLOGY, 9.

By: J. Cao n, J. Willett n, D. Dorris n & J. Meitzen n

author keywords: sex; estradiol; hormones; striatum; medium spiny neuron; nucleus accumbens; caudate-putamen; electrophysiology
TL;DR: Sex differences in rat MSN glutamatergic synaptic input and intrinsic excitability across striatal regions are reviewed, including evidence for estradiol-mediated sexual differentiation in the nucleus AcbC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Neither Knowledge Deficit nor NIMBY: Understanding Opposition to Hydraulic Fracturing as a Nuanced Coalition in Westmoreland County, Pennsylvania (USA)

ENVIRONMENTAL MANAGEMENT, 62(2), 305–322.

By: D. McLaughlin* & B. Cutts n

author keywords: Hydraulic fracturing; Q Methodology; Public perception
MeSH headings : Environmental Pollution / adverse effects; Environmental Pollution / analysis; Environmental Pollution / economics; Environmental Pollution / prevention & control; Humans; Hydraulic Fracking; Natural Gas; Pennsylvania; Politics; Public Opinion
TL;DR: This study uses Q methodology to examine emergent perspectives and sub-discourses within the fracking opposition debate in central Westmoreland County, PA, and suggests the inadequacy of relying on knowledge deficit and/or NIMBY explanations to fracking politics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 review

Mechanisms of carbon nanotube-induced pulmonary fibrosis: A physicochemical characteristic perspective

[Review of ]. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology, 10(3).

By: K. Duke & J. Bonner

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Listeria monocytogenes Source Distribution Analysis Indicates Regional Heterogeneity and Ecological Niche Preference among Serotype 4b Clones

MBIO, 9(2).

author keywords: Listeria monocytogenes; source distribution; emerging clones; serotype 4b
MeSH headings : Animals; Biodiversity; Ecosystem; Food Microbiology; Genotype; Humans; Listeria monocytogenes / classification; Listeria monocytogenes / genetics; Listeria monocytogenes / isolation & purification; Listeriosis / epidemiology; Listeriosis / microbiology; Listeriosis / veterinary; Molecular Epidemiology; Molecular Typing; North America / epidemiology; Serogroup; Water Microbiology
TL;DR: Findings suggest that in spite of the ubiquity of CC1, CC2, CC4, and CC6, regional heterogeneity in serotype 4b is substantially larger than previously surmised. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2018 article

Introduction to the special issue on endocrine disrupting chemicals and behavior

Barrett, E. S., & Patisaul, H. B. (2018, May). HORMONES AND BEHAVIOR, Vol. 101, pp. 1–2.

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Improving wood properties for wood utilization through multi-omics integration in lignin biosynthesis

Nature Communications, 9(1), 1579.

By: J. Wang n, M. Matthews n, C. Williams n, R. Shi n, C. Yang n, S. Tunlaya-Anukit n, H. Chen n, Q. Li* ...

MeSH headings : Gene Expression Regulation, Plant; Lignin / biosynthesis; Lignin / genetics; Plants, Genetically Modified / genetics; Populus / genetics; Populus / metabolism; Transcriptome / genetics; Trees / genetics; Trees / metabolism; Wood / chemistry; Wood / physiology; Xylem / metabolism
TL;DR: A multi-omics quantitative integrative analysis of lignin biosynthesis can advance the strategic engineering of wood for timber, pulp, and biofuels and may lead to greater understanding of other pathways for improved growth and adaptation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

How Segregation Makes Us Fat: Food Behaviors and Food Environment as Mediators of the Relationship Between Residential Segregation and Individual Body Mass Index

FRONTIERS IN PUBLIC HEALTH, 6(MAR).

By: M. Goodman*, S. Lyons*, L. Dean*, C. Arroyo* & J. Hipp n

Contributors: M. Goodman*, S. Lyons*, L. Dean*, C. Arroyo* & J. Hipp n

author keywords: Residential segregation; body mass index; food envrionment; Health Behavior; Mediation
TL;DR: Elements of the food environment, which form the context for dietary behaviors, are potential targets for interventions to reduce obesity in residentially segregated areas. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2018 journal article

Effects of maternal or paternal bisphenol A exposure on offspring behavior

HORMONES AND BEHAVIOR, 101, 68–76.

By: E. Harris n, H. Allardice n, A. Schenk* & E. Rissman n

MeSH headings : Animals; Anxiety / chemically induced; Anxiety / physiopathology; Behavior, Animal / drug effects; Benzhydryl Compounds / pharmacology; Endocrine Disruptors / pharmacology; Female; Male; Maternal Exposure / adverse effects; Mice; Mice, Inbred C57BL; Paternal Exposure / adverse effects; Phenols / pharmacology; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / physiopathology; Sexual Behavior, Animal / drug effects
TL;DR: These are among the first studies conducted to ask if BPA exposure via the sire affects offspring behavior and the first study to report effects of gestational BPA Exposure on pup USVs and adult operant responding. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2018 journal article

DNA Methylation Detection Using Resonance and Nanobowtie-Antenna-Enhanced Raman Spectroscopy

BIOPHYSICAL JOURNAL, 114(11), 2498–2506.

MeSH headings : 5-Methylcytosine / metabolism; DNA Methylation; Nanotechnology; Spectrum Analysis, Raman
TL;DR: It is shown that DNA carrying 5-methylcytosine modifications or methylated DNA (m-DNA) can be distinguished from DNA with unmodified cytosine by Raman spectroscopy enhanced by both a bowtie nanoantenna and excitation resonance, and the Raman resonance gain profile is consistent with A-term expectations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Carboxythiazole is a key microbial nutrient currency and critical component of thiamin biosynthesis

Scientific Reports, 8(1).

MeSH headings : Animals; Arabidopsis / metabolism; Arabidopsis Proteins / metabolism; Cell Line; Escherichia coli / metabolism; Mice; Nutrients / metabolism; Phytoplankton / metabolism; Thiamine / biosynthesis; Thiazoles / metabolism
TL;DR: It is demonstrated that 5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-carboxylic acid (cHET) is a useful in vivo B1 precursor for representatives of ubiquitous marine picoeukaryotic phytoplankton and Escherichia coli – drawing attention to cHET as a valuable exogenous micronutrient for microorganisms with ecological, industrial, and biomedical value. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

An object-oriented Bayesian network approach for establishing swine manure-borne natural estrogenic compounds budget

SCIENCE OF THE TOTAL ENVIRONMENT, 639, 815–825.

By: B. Lee*, S. Kullman n, E. Yost n, L. Worley-Davis n & K. Reckhow*

author keywords: Natural estrogens; Swine CAFO; Total facility estrogen budget; OOBN
MeSH headings : Animals; Bayes Theorem; Estradiol; Estrogens / analysis; Estrogens / metabolism; Estrone; Female; Lactation; Manure / analysis; North Carolina; Swine; Waste Disposal, Fluid / methods; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / metabolism
TL;DR: Results from the OOBN model indicate a rank order of lactating sows in terms of contribution of estrogen loads to the total natural estrogen budget, and E1 was found as the major estrogen metabolite with the summed concentrations of urine, feces, and flushing slurry wastes exceeding 3000 ng/l > 90% of the time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure

Cell Reports, 23(2), 327–336.

By: T. Frayling, R. Beaumont, S. Jones, H. Yaghootkar, M. Tuke, K. Ruth, F. Casanova, B. West ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold

CELL REPORTS, 23(3), 878–887.

By: K. Marsden n, R. Jain*, M. Wolman*, F. Echeverry, J. Nelson*, K. Hayer*, B. Miltenberg*, A. Pereda*, M. Granato*

MeSH headings : Acoustic Stimulation; Adaptor Proteins, Signal Transducing / genetics; Adaptor Proteins, Signal Transducing / metabolism; Animals; Axons / metabolism; Behavior, Animal; Calcium / metabolism; Cytoskeleton / metabolism; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein / metabolism; Hypersensitivity / metabolism; Hypersensitivity / pathology; Interneurons / metabolism; Larva / metabolism; Mutagenesis; Reflex, Startle / physiology; Zebrafish / growth & development; Zebrafish / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
TL;DR: It is shown that cyfip2 regulates the innate startle threshold by reducing neural activity in a small group of excitatory hindbrain interneurons, and this role is found to be critical to establishing an innate behavioral threshold. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Weaving Community-University Research and Action Partnerships for environmental justice

ACTION RESEARCH, 16(2), 173–189.

By: J. London*, K. Schwarz*, M. Cadenasso*, B. Cutts n, C. Mason*, J. Lim*, K. Valenzuela-Garcia, H. Smith*

author keywords: Environmental justice; urban agriculture; community-university partnerships; soil lead; action research
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Use of single-dose oral gabapentin to attenuate fear responses in cage-trap confined community cats: a double-blind, placebo-controlled field trial

JOURNAL OF FELINE MEDICINE AND SURGERY, 20(6), 535–543.

MeSH headings : Analgesics / administration & dosage; Animals; Behavior, Animal / drug effects; Cats; Cyclohexanecarboxylic Acids / administration & dosage; Double-Blind Method; Fear; Female; Gabapentin / administration & dosage; Male; Physical Examination / veterinary; Random Allocation
TL;DR: This study supports the hypothesis that 50 mg or 100 mg gabapentin reduces fear responses in confined community cats without measurable sedation over 3 h post-administration vs placebo, and Gabapentin treatment was well tolerated in this population of cats. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2018 journal article

The neurological toxicity of heavy metals: A fish perspective

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 208, 12–19.

By: A. Green n & A. Planchart n

Contributors: A. Green n & A. Planchart n

MeSH headings : Animals; Animals, Genetically Modified; Behavior, Animal / drug effects; Disease Models, Animal; Gene Expression Regulation, Developmental / drug effects; Heavy Metal Poisoning, Nervous System / etiology; Heavy Metal Poisoning, Nervous System / genetics; Heavy Metal Poisoning, Nervous System / metabolism; Heavy Metal Poisoning, Nervous System / pathology; Humans; Metals, Heavy / toxicity; Nerve Degeneration; Nervous System / drug effects; Nervous System / metabolism; Nervous System / pathology; Nervous System / physiopathology; Neurons / drug effects; Neurons / metabolism; Neurons / pathology; Risk Assessment; Water Pollutants, Chemical / toxicity; Zebrafish / genetics; Zebrafish / metabolism
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2018 journal article

The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum

DEVELOPMENTAL BIOLOGY, 439(2), 80–91.

By: M. Womble n, N. Amin n & N. Nascone-Yoder n

author keywords: Xenopus; Liver; Left-right asymmetry; Endoderm; Morphogenesis; Pitx2
MeSH headings : Animals; Body Patterning / genetics; Diverticulum / embryology; Diverticulum / metabolism; Embryo, Nonmammalian / metabolism; Gene Expression Regulation, Developmental / genetics; Homeodomain Proteins / metabolism; Homeodomain Proteins / physiology; Liver / embryology; Liver / physiology; Morphogenesis / physiology; Transcription Factors / metabolism; Xenopus / embryology; Xenopus / physiology; Xenopus Proteins / metabolism; Xenopus Proteins / physiology
TL;DR: Side-specific gain- and loss-of-function studies reveal that asymmetric expression of the left-right determinant Pitx2c elicits distinct epithelial morphogenesis events in the left side of the diverticulum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Spatial regression with an informatively missing covariate: Application to mapping fine particulate matter

Environmetrics, 29(4), e2499.

author keywords: aerosol optical depth; air pollution; informative missingness; kriging; MCMC; predictive process
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2018 journal article

Quantitative mass spectrometry imaging of glutathione in healthy and cancerous hen ovarian tissue sections by infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI)

ANALYST, 143(3), 654–661.

By: M. Nazari n, M. Bokhart n, P. Loziuk n & D. Muddiman n

MeSH headings : Animals; Chickens; Chromatography, Liquid; Female; Glutathione / analysis; Ovarian Neoplasms / diagnostic imaging; Ovary / diagnostic imaging; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry
TL;DR: A ∼2-fold increase in the concentration of GSH in cancer tissue compared to the healthy tissue was observed using both techniques, and possible reasons for the difference between absolute concentration values obtained using IR-MALDESI QMSI and LC-MS/MS are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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