Works Published in 2024
Displaying works 21 - 38 of 38 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2024 journal article
The NLRP3 Inflammasome Is Dispensable in Methicillin-Resistant <i>Staphylococcus aureus</i> Urinary Tract Infection
PATHOGENS, 13(2).
author keywords: MRSA; UTI; NLRP3; inflammasome
TL;DR:
It is suggested that MRSA-induced urinary NLRP3 activity does not play a role in the pathophysiology of the ascending UTI, and histopathological analysis of MRSA-infected bladder and kidney sections from Nlrp3−/− and WT mice showed similar inflammation.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 18, 2024
2024 journal article
Investigating mouse hepatic lipidome dysregulation following exposure to emerging per- and polyfluoroalkyl substances (PFAS)
Chemosphere.
TL;DR:
Results provide valuable insight into the liver bioaccumulation and molecular mechanisms of GenX- and NBP2-induced hepatotoxicity and various specific fatty acyls were greatly impacted, indicating alteration of inflammation, oxidative stress, and cellular signaling processes due to emerging PFAS exposure.
(via Semantic Scholar)
Source: ORCID
Added: March 15, 2024
2024 article
Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis
Monangi, N. K., Xu, H., Fan, Y.-M., Khanam, R., Khan, W., Deb, S., … Muglia, L. J. (2024, January). AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol. 119, pp. 221–231.
author keywords: nutrition; pregnancy; copper; preterm birth; gestational duration; in; acute-phase reactants
TL;DR:
A robust negative association between maternal mid-gestation Cu concentration and gestational duration and positive association with risk for preterm birth is supported and could be used as a potential marker of the integrated inflammatory pathways during pregnancy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: March 11, 2024
2024 article
The people behind the papers - Julia Grzymkowski and Nanette Nascone-Yoder
Grzymkowski, J., & Nascone-Yoder, N. (2024, January). DEVELOPMENT, Vol. 151.
TL;DR:
Exposure of Xenopus embryos to atrazine, a widely-used herbicide, can disrupt cellular metabolism in the developing gut tube and lead to intestinal malrotation, a prevalent birth anomaly.
(via Semantic Scholar)
Source: Web Of Science
Added: March 11, 2024
2024 journal article
Developmental regulation of cellular metabolism is required for intestinal elongation and rotation
DEVELOPMENT, 151(1).
author keywords: Intestine; Metabolism; Rotation; Electron transport chain; Elongation; Atrazine; Xenopus
TL;DR:
Roles for metabolism in gut morphogenesis are revealed and implicate defective gut tube elongation and/or metabolic perturbations in the etiology of intestinal malrotation.
(via Semantic Scholar)
Source: Web Of Science
Added: March 11, 2024
2024 journal article
Pesticide exposure, birth size, and gestational age in the ISA birth cohort, Costa Rica
ENVIRONMENTAL EPIDEMIOLOGY, 8(2).
TL;DR:
Prenatal exposure to chlorpyrifos and 2,4-D, and, possibly, mancozeb/ETU, and, possibly, mancozeb/ETU, may impair fetal growth.
(via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 14, 2024
2024 journal article
Maternal childhood adversity and infant epigenetic aging: Moderation by restless sleep during pregnancy
DEVELOPMENTAL PSYCHOBIOLOGY, 66(2).
author keywords: adverse childhood experience; epigenomics; pregnancy; sleep
TL;DR:
Preliminary evidence is provided that maternal childhood adversity and sleep may influence the infant epigenome and there was evidence of an interaction between maternal ACEs and restless sleep in predicting infant epigenetic age acceleration using the EPIC gestational age clock.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: February 12, 2024
2024 journal article
Flunixin meglumine tissue residues after intravenous administration in goats
FRONTIERS IN VETERINARY SCIENCE, 10.
author keywords: flunixin; goat; residues; tolerance limit method; withdrawal interval; withdrawal time
TL;DR:
Since any detection of flunixin residues at slaughter found in goat tissues is considered a violative residue, a conservative withdrawal interval of 17 days was calculated to ensure levels of flunixin fell below the regulatory limits of detection in liver, kidney, and muscle tissues.
(via Semantic Scholar)
Source: Web Of Science
Added: February 12, 2024
2024 journal article
Questionnaire-based exposome-wide association studies for common diseases in the Personalized Environment and Genes Study
Exposome.
TL;DR:
An exposome-wide association study to examine single exposure models and their associations with 11 common complex diseases, namely allergic rhinitis, asthma, bone loss, fibroids, high cholesterol, hypertension, iron-deficient anemia, ovarian cysts, lower GI polyps, migraines, and type 2 diabetes is performed.
(via Semantic Scholar)
Source: ORCID
Added: February 10, 2024
2024 journal article
Interactive data sharing for multiple questionnaire-based exposome-wide association studies and exposome correlations in the Personalized Environment and Genes Study
Exposome.
TL;DR:
The PEGS Explorer web application is developed to explore exposure correlations in data from the diverse North Carolina-based Personalized Environment and Genes Study (PEGS) that were rigorously calculated to account for differing data types and previously published results from ExWAS.
(via Semantic Scholar)
Source: ORCID
Added: February 10, 2024
2024 journal article
Thermal Threats to Freshwater Mussels: An Empirical Stream Assessment
DIVERSITY-BASEL, 16(1).
author keywords: Unionidae; climate change; global change; thermal buffer; fish; temperature; substrate; exceedance; species richness
TL;DR:
Fish species richness was related to the thermal regime, indicating that species interactions may be an important driver of freshwater mussel responses to global change, and models estimating the relation between the water column and substrate temperatures more realistically characterize ambient temperature exposures more realistically characterize ambient temperature exposures.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 2, 2024
2024 article
Effects of 4 Testing Arena Sizes and 11 Types of Embryo Media on Sensorimotor Behaviors in Wild-Type and <i>chd7</i> Mutant Zebrafish Larvae
Hodorovich, D. R., Harris, T. F., Burton, D. F., Neese, K. M., Bieler, R. A., Chudasama, V., & Marsden, K. C. (2024, February 1). ZEBRAFISH, Vol. 2.
author keywords: zebrafish; behavior; acoustic startle; embryo media; arena size; chd7
TL;DR:
The data show that testing arena size impacts acoustic startle sensitivity and kinematics, as well as spontaneous locomotion and thigmotaxis, with fish tested in larger arenas displaying reduced startle sensitivity and increased locomotion.
(via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 2, 2024
2024 journal article
Removal of Per- and Polyfluoroalkyl substances by anion exchange resins: Scale-up of rapid small-scale column test data
WATER RESEARCH, 249.
author keywords: Drinking water treatment; Remediation; Perfluoroalkyl acids; Per- and polyfluoroalkyl ether acids
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 29, 2024
2024 article
Developmental exposure to pesticides that disrupt retinoic acid signaling causes persistent retinoid and behavioral dysfunction in zebrafish
Hawkey, A. B., Shekey, N., Dean, C., Asrat, H., Koburov, R., Holloway, Z. R., … Levin, E. D. (2024, January 17). TOXICOLOGICAL SCIENCES, Vol. 1.
author keywords: zebrafish; development; neurobehavioral toxicology; retinoic acid receptors
TL;DR:
It is demonstrated that early developmental exposure to environmental toxicants that interfere with RA signaling cause short as well as long-term behavioral disruption in a well-established zebrafish behavioral model and the meaning of the RA adverse outcome pathway is expanded, indicating that observed effects likely correspond with the nature of underlying homeostatic effects.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 29, 2024
2024 journal article
Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs)
Exposome.
TL;DR:
This paper introduces the exposome-wide association study (ExWAS), an approach designed for systematic discovery of relationships between phenotypes and various exposures, identifying significant associations while controlling for multiple comparisons.
(via Semantic Scholar)
Source: ORCID
Added: January 26, 2024
2024 article
Pharmacokinetics of intranasal and intramuscular flunixin in healthy grower pigs
Wiloch, E. E., Enomoto, H., Smith, L., Baynes, R. E., & Messenger, K. M. (2024, January 11). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.
author keywords: analgesia; flunixin; intranasal; pharmacokinetics; swine
TL;DR:
Intranasal flunixin has similar, although variable, pharmacokinetic parameters to the intramuscular route, making it a viable route of administration for use in grower swine, according to this study.
(via Semantic Scholar)
Source: Web Of Science
Added: January 16, 2024
2024 journal article
Guided optimization of ToxPi model weights using a Semi-Automated approach
COMPUTATIONAL TOXICOLOGY, 29.
author keywords: Machine learning; Feature weighting; Exposure assessment; Chemical toxicity; Ordinal regression; Genetic algorithm
Sources: Web Of Science, NC State University Libraries
Added: January 16, 2024
2024 journal article
Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth
EPIGENETICS, 19(1).
author keywords: ACEs; pregnancy; methylation; imprinted genes; race
TL;DR:
Findings from this study suggest that maternal ACEs, discrimination, and financial stress are associated with newborn aberrant methylation in imprinted gene regions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(OpenAlex)
Source: Web Of Science
Added: January 2, 2024
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