Works Published in 2015

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Displaying works 81 - 100 of 154 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts

NATURE COMMUNICATIONS, 6.

By: D. Parikh*, E. Fouquerel*, C. Murphy*, H. Wang n & P. Opresko n

MeSH headings : Cell Line; Cell Proliferation; Cell Survival; DNA Damage / radiation effects; DNA Repair / physiology; Fibroblasts / cytology; Fibroblasts / radiation effects; Humans; Telomere / radiation effects; Ultraviolet Rays
TL;DR: Examination of the efficiency of photoproduct formation and removal at telomeres purified from UVC irradiated cells at various recovery times provides new evidence that telomes are partially protected from ultraviolet irradiation and that NER preserves telomere integrity. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Part 2: Sensitivity comparisons of the mayfly Centroptilum triangulifer to Ceriodaphnia dubia and Daphnia magna using standard reference toxicants; NaCl, KCl and CuSO4

CHEMOSPHERE, 139, 597–603.

By: K. Struewing, J. Lazorchak*, P. Weaver, B. Johnson*, D. Funk* & D. Buchwalter n

author keywords: Mayfly; Comparative toxicity; NaCl; KCl; CuSO4
MeSH headings : Animals; Copper Sulfate / toxicity; Daphnia / drug effects; Ephemeroptera / drug effects; Potassium Chloride / toxicity; Reference Standards; Sodium Chloride / toxicity; Toxicity Tests / standards; Water Pollutants, Chemical / toxicity
TL;DR: C. triangulifer was the most sensitive species in NaCl acute and chronic growth tests and has great potential and benefits for use in ecotoxicological studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Part 1: Laboratory culture of Centroptilum triangulifer (Ephemeroptera: Baetidae) using a defined diet of three diatoms

CHEMOSPHERE, 139, 589–596.

By: P. Weaver, J. Lazorchak*, K. Struewing, S. DeCelles, D. Funk*, D. Buchwalter n, B. Johnson*

author keywords: Benthic macroinvertebrates; Water quality criteria; Ecotoxicology; Parthenogenetic mayfly; Culture method; Diatoms
MeSH headings : Animals; Body Weight; Culture Techniques / methods; Diatoms; Diet; Ecosystem; Ephemeroptera / growth & development; Ephemeroptera / physiology; Female; Fertility; Laboratories; Oviposition; Rivers; Survival Analysis; Toxicity Tests
TL;DR: Establishment of this culturing protocol provides a more ecologically relevant species for toxicity testing and aids in further stressor identification for stream bioassessments. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections

Journal of the American Veterinary Medical Association, 247(8), 938–944.

By: M. Jacob*, J. Hoppin*, N. Steers*, J. Davis*, G. Davidson*, B. Hansen, K. Lunn*, K. Murphy, M. Papich*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cross-Sectional Studies; Data Collection; Drug Resistance, Bacterial; Education, Veterinary; Female; Hospitals, Animal; Humans; Male; Professional Practice; Schools, Veterinary; United States; Veterinarians
TL;DR: Findings indicated that veterinarians at this teaching hospital were concerned about antimicrobial resistance, thought antimicrobials were overprescribed, and supported restricting use of certain antimicrobial classes in companion animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 review

Males on demand: the environmental-neuro-endocrine control of male sex determination in daphnids

[Review of ]. FEBS JOURNAL, 282(21), 4080–4093.

By: G. LeBlanc n & E. Medlock n

author keywords: doublesex; epigenetic; farnesoic acid O-methyltransferase; NMDA receptor; nutrition; parthenogenesis; photoperiod; sex lethal; temperature; transformer
MeSH headings : Animals; Daphnia / genetics; Daphnia / growth & development; Daphnia / physiology; Environment; Fatty Acids, Unsaturated / physiology; Female; Food; Male; Models, Biological; Neurosecretory Systems / physiology; Parthenogenesis / genetics; Parthenogenesis / physiology; Phenotype; Population Density; Seasons; Sex Determination Processes / genetics; Sex Determination Processes / physiology; Signal Transduction
TL;DR: This review describes the cascade of events beginning with environmental cues and ending with changes in gene expression that dictate male sex determination in daphnids, the initial event in the switch to sexual reproduction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Genotype-epigenotype interaction at the IGF2 DMR

Genes, 6(3), 777–789.

By: S. Murphy, E. Erginer, Z. Huang, Z. Visco & C. Hoyo

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

Nature Communications, 6.

By: H. Corvol, S. Blackman, P. Boelle, P. Gallins, R. Pace, J. Stonebraker, F. Accurso, A. Clement ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Differential Gene Expression across Breed and Sex in Commercial Pigs Administered Fenbendazole and Flunixin Meglumine

PLOS ONE, 10(9), e0137830.

By: J. Howard n, A. O’Nan n, C. Maltecca n, R. Baynes n & M. Ashwell n

Ed(s): F. Kobeissy

MeSH headings : Animals; Breeding; Clonixin / analogs & derivatives; Clonixin / pharmacology; Cytochrome P-450 Enzyme System / genetics; Female; Fenbendazole / pharmacology; Gene Expression Regulation / drug effects; Male; Orchiectomy; Real-Time Polymerase Chain Reaction; Sus scrofa / genetics
Sources: Web Of Science, Crossref
Added: August 6, 2018

2015 journal article

Meeting multiple water quality objectives through treatment using locally generated char: improving organoleptic properties and removing synthetic organic contaminants and disinfection by-products

JOURNAL OF WATER SANITATION AND HYGIENE FOR DEVELOPMENT, 5(3), 359–372.

author keywords: adsorption; biochar; charcoal; chemical water contaminants; point-of-use water treatment
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Feasibility of Using Traditional Kiln Charcoals in Low-Cost Water Treatment: Role of Pyrolysis Conditions on 2,4-D Herbicide Adsorption

ENVIRONMENTAL ENGINEERING SCIENCE, 32(11), 912–921.

By: J. Kearns n, D. Knappe n & R. Summers*

Contributors: J. Kearns n, D. Knappe n & R. Summers*

author keywords: 2,4-D; adsorption; biochar; charcoal; decentralized water treatment; engineering for developing communities; low cost adsorbents
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
6. Clean Water and Sanitation (OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Correlation between maternal and infant cortisol varies by breastfeeding status

INFANT BEHAVIOR & DEVELOPMENT, 40, 252–258.

author keywords: Breastfeeding; Cortisol; Human milk; Stress
MeSH headings : Adult; Aging / physiology; Body Weight / physiology; Breast Feeding / psychology; Cross-Sectional Studies; Educational Status; Ethnicity; Female; Humans; Hydrocortisone / metabolism; Income; Infant; Infant Food; Linear Models; Male; Mothers; Saliva / chemistry; Saliva / metabolism; Sex Characteristics; Socioeconomic Factors; Stress, Psychological / metabolism
TL;DR: The data suggest that several factors may contribute to cortisol synchrony observed in mother/infant dyads, including the transfer of cortisol in human milk, physical interaction such as skin-to-skin contact, and shared environment, and household income as a possible contributor. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Cancer incidence and metolachlor use in the Agricultural Health Study: An update

International Journal of Cancer, 137(11), 2630–2643.

By: S. Silver*, S. Bertke*, C. Hines*, M. Alavanja*, J. Hoppin n, J. Lubin*, J. Rusiecki*, D. Sandler*, L. Beane Freeman*

author keywords: cancer; epidemiology; pesticide; occupation
MeSH headings : Acetamides / toxicity; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Carcinogens / toxicity; Cohort Studies; Female; Herbicides / toxicity; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Prospective Studies
TL;DR: A suggestion of an association between metolachlor and liver cancer among pesticide applicators is a novel finding and echoes observation of increased liver neoplasms in some animal studies, however, the findings for both liver cancer and follicular cell lymphoma warrant follow‐up to better differentiate effects of metolchlor use from other factors. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Predicting characteristics of rainfall driven estrogen runoff and transport from swine AFO spray fields

SCIENCE OF THE TOTAL ENVIRONMENT, 532, 571–580.

By: B. Lee*, S. Kullman n, E. Yost n, M. Meyer*, L. Worley-Davis n, C. Williams n, K. Reckhow*

author keywords: Estrogen runoff and transport; Bayesian network model; Swine animal feeding operation; Spray fields
MeSH headings : Agriculture / methods; Animal Feed; Animals; Bayes Theorem; Environmental Monitoring / methods; Estrogens / analysis; Geologic Sediments; Manure; Models, Chemical; Rain; Soil / chemistry; Swine; Water Movements; Water Pollutants, Chemical / analysis; Water Pollution, Chemical / statistics & numerical data
TL;DR: What-if scenario analyses suggest that planting Bermuda grass in the spray fields is likely to reduce runoff losses of natural estrogens near the water bodies and ecosystems, as compared to planting of soybeans. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Pesticide exposure and end-stage renal disease risk among wives of pesticide applicators in the Agricultural Health Study

Environmental Research, 143, 198–210.

By: J. Lebov*, L. Engel*, D. Richardson*, S. Hogan*, D. Sandler* & J. Hoppin n

author keywords: Pesticide exposure; End-stage renal disease; Farm women; Agricultural exposures
MeSH headings : Adolescent; Adult; Aged; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Farmers / statistics & numerical data; Female; Humans; Incidence; Iowa / epidemiology; Kidney Failure, Chronic / chemically induced; Kidney Failure, Chronic / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Pesticides / analysis; Pesticides / toxicity; Proportional Hazards Models; Prospective Studies; Risk Factors; Spouses / statistics & numerical data; Surveys and Questionnaires; Time Factors; Young Adult
TL;DR: ESRD may be associated with direct and/or indirect exposure to pesticides among farm women and future studies should evaluate indirect exposure risk among other rural populations. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Organophosphate insecticide use and cancer incidence among spouses of pesticide applicators in the Agricultural Health Study

Occupational and Environmental Medicine, 72(10), 736–744.

By: C. Lerro*, S. Koutros*, G. Andreotti*, M. Friesen*, M. Alavanja*, A. Blair*, J. Hoppin n, D. Sandler* ...

MeSH headings : Adult; Age Distribution; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Cohort Studies; Diazinon / adverse effects; Female; Humans; Incidence; Insecticides / adverse effects; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Organophosphates / adverse effects; Retrospective Studies; Risk Assessment; Spouses / statistics & numerical data; Survival Rate; Young Adult
TL;DR: This study represents the first comprehensive analysis of OP use and cancer risk among women, suggesting potential for hormonally-mediated effects. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

In vitro screening for population variability in toxicity of pesticide-containing mixtures

ENVIRONMENT INTERNATIONAL, 85, 147–155.

author keywords: Pesticide; Mixture; Population
MeSH headings : Black People / genetics; Cell Culture Techniques; Cell Line; Cell Survival / drug effects; Cell Survival / genetics; Complex Mixtures / analysis; Complex Mixtures / toxicity; Dose-Response Relationship, Drug; Genome-Wide Association Study; Genotype; Hazardous Substances / analysis; Hazardous Substances / toxicity; Humans; Hydrocarbons, Chlorinated / analysis; Hydrocarbons, Chlorinated / toxicity; Multivariate Analysis; Pesticides / analysis; Pesticides / toxicity; Polymorphism, Genetic; Reproducibility of Results; White People / genetics
TL;DR: A combination of in vitro human population-based cytotoxicity screening followed by dosimetric adjustment and comparative population genomics analyses enables quantitative evaluation of human health hazard from complex environmental mixtures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation

CHROMOSOME RESEARCH, 23(4), 681–708.

author keywords: Leukemia; Canine; Chromosome; Comparative genomic hybridization; Comparative genomics
MeSH headings : Algorithms; Animals; Cell Transformation, Neoplastic / genetics; Chromosome Aberrations; Chromosome Mapping; Cluster Analysis; Comparative Genomic Hybridization; Conserved Sequence; DNA Copy Number Variations; Disease Models, Animal; Dogs; Evolution, Molecular; Female; Gene Dosage; Genome-Wide Association Study; Genomic Library; Genomics; Humans; In Situ Hybridization, Fluorescence; Leukemia / diagnosis; Leukemia / genetics; Leukemia / metabolism; Male
TL;DR: The use of canine leukemia as a relevant in vivo model for human leukemia is supported and the need to further explore the conserved genomic regions of interest for their clinical impact is justified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

Human Molecular Genetics, 24(15), 4464–4479.

By: E. Demerath, W. Guan, M. Grove, S. Aslibekyan, M. Mendelson, Y. Zhou, A. Hedman, J. Sandling ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Budgett's frog (Lepidobatrachus laevis): A new amphibian embryo for developmental biology

DEVELOPMENTAL BIOLOGY, 405(2), 291–303.

author keywords: Lepidobatrachus; Xenopus; Amphibian; Embryo; Stages; Scaling
MeSH headings : Amphibians; Animals; Anura / embryology; Cell Lineage; Developmental Biology; Embryonic Development; Immunohistochemistry; Models, Animal; Morphogenesis; Organogenesis; Regeneration; Species Specificity; Xenopus laevis / physiology
TL;DR: The Budgett's frog is described, an unusual species with eggs that are over twice the diameter of laboratory Xenopus, and embryos that can tolerate higher temperatures to develop into a tadpole four times more rapidly, which substantially accelerates the pace of experimentation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity

CHROMOSOME RESEARCH, 23(4), 663–680.

By: R. Omeir*, R. Thomas n, B. Teferedegne*, C. Williams n, G. Foseh*, J. Macauley*, L. Brinster*, J. Beren* ...

author keywords: Neoplastic transformation; Tumorigenicity; Canine chromosomes; Comparative genomic hybridization (CGH); Fluorescence in situ hybridization (FISH); Madin-Darby canine kidney (MDCK) cell line; CKB1-3T7 cell line
MeSH headings : Animals; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic / genetics; Cells, Cultured; Chromosome Aberrations; DNA Copy Number Variations; Dogs; In Situ Hybridization, Fluorescence; Karyotype; Madin Darby Canine Kidney Cells; Male; Neoplasms / genetics; Neoplasms / pathology
TL;DR: Through integrated cytogenomic and phenotypic characterization of serial passages of CKB1-3T7 from initiation to development of a tumorigenic phenotype, this work presents a robust and readily accessible model of spontaneous neoplastic transformation that overcomes many of the limitations of earlier studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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