Works Published in 2020
Displaying works 381 - 400 of 779 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 review
Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies
[Review of ]. JOURNAL OF MATERIALS CHEMISTRY B, 8(32), 7062–7075.
MeSH headings : Animals; Cell Culture Techniques; Cell Line; Cell Movement; Cellular Microenvironment; Hemostasis / drug effects; Humans; Hydrogels / chemistry; Hydrogels / metabolism; Macrophages / metabolism; Microfluidics; Models, Animal; Skin; Stereolithography; Wound Healing / drug effects
TL;DR:
This review provides a brief overview of the wound healing process and in vivo assays, and critically review the current state of microphysiological systems and supporting technologies for modelling and studying wound healing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 7, 2020
2020 journal article
Enantioselective Synthesis of Cyclopropanone Equivalents and Application to the Formation of Chiral β-Lactams
Angewandte Chemie International Edition, 59(42), 18655–18661.
author keywords: cycloaddition; lactams; ring expansion; small-ring compounds; synthetic methods
TL;DR:
Both the electronic and steric nature of the sulfonyl moiety were found to have a crucial impact on the rate of equilibration to the corresponding cyclopropanone, highlighting their modular nature and the potential for their widespread adoption as synthetic intermediates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 7, 2020
2020 journal article
Sex differences in the acute and subchronic lung inflammatory responses of mice to nickel nanoparticles
NANOTOXICOLOGY, 14(8), 1058–1081.
author keywords: Nickel nanoparticles; inflammation; lung; sex; susceptibility
MeSH headings : Animals; Bronchoalveolar Lavage Fluid / cytology; Chemokine CXCL1 / metabolism; Female; Humans; Inhalation Exposure; Interleukin-6 / metabolism; Lung / drug effects; Lung / immunology; Lung / pathology; Male; Metal Nanoparticles / toxicity; Mice; Mice, Inbred C57BL; Neutrophils / cytology; Neutrophils / drug effects; Nickel / toxicity; Pneumonia / chemically induced; Pneumonia / pathology; STAT Transcription Factors / metabolism; Sex Characteristics; Signal Transduction; Toxicity Tests, Acute; Toxicity Tests, Subchronic
TL;DR:
Sex differences in the lung inflammatory response of mice to NiNPs that has implications for human disease are demonstrated and indicate that susceptibility of males to acute lung inflammation involves enhanced neutrophilia with increased CXCL1 and IL-6/STAT3 signaling, whereas susceptibility to subchronic lunginflammation involves enhanced monocytic infiltration withIncreased CXcl1 and CCL2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 7, 2020
2020 journal article
Development of a coarse-grained lipid model, LIME 2.0, for DSPE using multistate iterative Boltzmann inversion and discontinuous molecular dynamics simulations
FLUID PHASE EQUILIBRIA, 521.
author keywords: Coarse-graining; Multi-state iterative Boltzmann inversion; Multiple square well; Discontinuous molecular dynamics; simulation; Lipid bilayer
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 7, 2020
2020 article
Simultaneous Soluble Secretion and Surface Display of Proteins in Saccharomyces cerevisiae Using Inefficient Ribosomal Skipping
GENOTYPE PHENOTYPE COUPLING: METHODS AND PROTOCOLS, Vol. 2070, pp. 321–334.
author keywords: Yeast surface display; Self-cleaving peptides; 2A peptides; Secretion; Ribosomal skipping; Sso7d
MeSH headings : Peptide Library; Peptides / metabolism; Protein Biosynthesis; Recombinant Proteins / biosynthesis; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Ribosomes / metabolism; Saccharomyces cerevisiae / chemistry; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism
TL;DR:
This work has developed a platform that exploits inefficient ribosomal skipping by the F2A peptide for simultaneous soluble secretion and cell surface display of protein in the yeast Saccharomyces cerevisiae and provides specific recommendations for the purification of the secreted protein.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 7, 2020
2020 journal article
One health in regenerative medicine: report on the second Havemeyer symposium on regenerative medicine in horses
REGENERATIVE MEDICINE, 15(6), 1775–1787.
author keywords: animal model; bone marrow concentrate; horse; interleukin-1 receptor antagonist protein; mesenchymal stem cell; platelet rich plasma; stem cell
MeSH headings : Animals; Cell Differentiation; Congresses as Topic; Horse Diseases / therapy; Horses; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / cytology; One Health; Regenerative Medicine
TL;DR:
Findings from a workshop on the development of translational regenerative medicine in the equine field were disseminated and five themes emerged: stem cell characterization and tenogenic differentiation, interactions between mesenchymal stem cells, other cells and the environment, and clinical use of regenerative therapies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 31, 2020
2020 review
Advances of exosome isolation techniques in lung cancer
[Review of ]. MOLECULAR BIOLOGY REPORTS, 47(9), 7229–7251.
author keywords: Lung cancer; Exosome; Multi-vesicular bodies; Extracellular vesicles; MicroRNAs
MeSH headings : Biomarkers, Tumor / blood; Biomarkers, Tumor / isolation & purification; Cell-Free Nucleic Acids / blood; Cell-Free Nucleic Acids / isolation & purification; Circulating Tumor DNA / blood; Circulating Tumor DNA / isolation & purification; Exosomes / metabolism; Exosomes / pathology; Humans; Lung Neoplasms / blood; Lung Neoplasms / diagnosis; Lung Neoplasms / pathology
TL;DR:
This review summarizes the recent investigations regarding isolation and also the characterization of exosomes of LC cells, and discusses the noncoding RNAs as biomarkers and their applications in the diagnosis and prognosis of LC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 31, 2020
2020 journal article
Parahydrogen‐Induced Hyperpolarization of Gases
Angewandte Chemie International Edition, 59(41), 17788–17797.
Contributors: K. Kovtunov *, I. Koptyug*, M. Fekete *, S. Duckett *, T. Theis n , B. Joalland *, E. Chekmenev *
author keywords: hyperpolarization; MRI; NMR; parahydrogen; spectroscopy
MeSH headings : Catalysis; Gases / chemistry; Hydrogen / chemistry; Magnetic Resonance Imaging / methods; Magnetic Resonance Spectroscopy / methods
TL;DR:
The focus of this Minireview is to highlight selected advances in the field of parahydrogen-induced polarization for the production of hyperpolarized compounds, which can be potentially employed as inhalable contrast agents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 31, 2020
2020 journal article
Rational ligand choice extends the SABRE substrate scope
Chemical Communications, 56(65), 9336–9339.
Contributors: J. Colell *, A. Logan *, Z. Zhou *, J. Lindale *, R. Laasner *, R. Shchepin *, E. Chekmenev *, V. Blum *
TL;DR:
Chelating ligands for Signal Amplification By Reversible Exchange (SABRE) catalysts that permit hyperpolarisation on otherwise sterically hindered substrates are reported on.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 31, 2020
2020 review
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part I: Cattle and swine
[Review of ]. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 43(5), 385–420.
author keywords: blood flow; food safety; organ weight; physiologically based pharmacokinetic model; withdrawal interval
MeSH headings : Animals; Cattle / physiology; Drug Residues; Models, Biological; Pharmaceutical Preparations / metabolism; Pharmacokinetics; Swine / physiology
TL;DR:
These compiled data provide a comprehensive physiological parameter database for developing PBPK models of chemicals in cattle and swine to support animal‐derived food safety assessment and provide a basis to compile data in other food animal species, including goats, sheep, chickens, and turkeys.
(via Semantic Scholar)
onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 31, 2020
2020 review
Agricultural nanodiagnostics for plant diseases: recent advances and challenges
[Review of ]. NANOSCALE ADVANCES, 2(8), 3083–3094.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 31, 2020
2020 journal article
Metabolite collision cross section prediction without energy-minimized structures
The Analyst, 145(16), 5414–5418.
MeSH headings : Ion Mobility Spectrometry; Mass Spectrometry
TL;DR:
It is shown for the first time that accurately predicting CCS values with simple models for the largest library of metabolite cross sections is indeed possible, achieving a root mean square error of 7.0 Å2 (median error of ∼2%) using linear methods accesible to most researchers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 31, 2020
2020 journal article
Temporal and spatial analysis of per and polyfluoroalkyl substances in surface waters of Houston ship channel following a large-scale industrial fire incident
Environmental Pollution, 265(B), 115009.
MeSH headings : Drinking Water / analysis; Fires; Fluorocarbons / analysis; Texas; Water Pollutants, Chemical / analysis
TL;DR:
A major peak in the level of many PFAS is found in the days and weeks after the ITC incident and a gradual decline over several months with patterns consistent with the tide- and wave-associated water movements.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 31, 2020
2020 article
Purification of animal immunoglobulin G (IgG) using peptoid affinity ligands
BIOTECHNOLOGY PROGRESS.
MeSH headings : Animals; Chickens; Chromatography, Affinity; Goats; Immunoglobulin G / chemistry; Immunoglobulin G / immunology; Immunoglobulin G / isolation & purification; Immunoglobulins / chemistry; Immunoglobulins / isolation & purification; Ligands; Mice; Peptoids / chemistry; Protein Binding / drug effects; Rabbits; Sheep
TL;DR:
The peptoid PL16, previously isolated from an ensemble of peptoid variants of the IgG-binding peptide HWRGWV, was utilized in this work as affinity ligand on WorkBeads resin for the purification of immunoglobulin G from a variety of mammalian sources and chicken immunoglobeulin Y (IgY).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 31, 2020
2020 journal article
Engineering the cellulolytic extreme thermophile Caldicellulosiruptor bescii to reduce carboxylic acids to alcohols using plant biomass as the energy source
Journal of Industrial Microbiology and Biotechnology, 47(8), 585–597.
author keywords: Thermophile; Biofuels; Lignocellulose; Metabolic engineering; Caldicellulosiruptor
MeSH headings : Alcohol Dehydrogenase / genetics; Alcohol Dehydrogenase / metabolism; Aldehyde Oxidoreductases / genetics; Aldehyde Oxidoreductases / metabolism; Biofuels / analysis; Biomass; Caldicellulosiruptor / genetics; Carboxylic Acids / metabolism; Ethanol / metabolism; Fermentation; Lignin / metabolism; Microorganisms, Genetically-Modified; Oxidation-Reduction; Panicum / metabolism; Panicum / microbiology; Pyrococcus furiosus / enzymology; Thermoanaerobacter / enzymology
TL;DR:
This work investigates the ability of engineered C.bescii to generate alcohols from carboxylic acids and converts them to alcohol using both crystalline cellulose and switchgrass as sources of reductant for alcohol production, the first instance of an acid to alcohol conversion pathway in a cellulolytic microbe.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science; OpenAlex)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 31, 2020
2020 journal article
Influence of Duration of Injury on Diffusion Tensor Imaging in Acute Canine Spinal Cord Injury
JOURNAL OF NEUROTRAUMA, 37(21), 2261–2267.
author keywords: dog; fractional anisotropy; imaging biomarker; intervertebral disc herniation; mean diffusivity
MeSH headings : Animals; Diffusion Tensor Imaging / methods; Dogs; Intervertebral Disc Displacement / diagnostic imaging; Intervertebral Disc Displacement / pathology; Intervertebral Disc Displacement / veterinary; Spinal Cord Injuries / diagnostic imaging; Spinal Cord Injuries / pathology; Spinal Cord Injuries / veterinary; Time Factors
TL;DR:
Investigating the impact of duration of injury on DTI indices in dogs with acute, spontaneous SCI due to thoracolumbar intervertebral disc herniation and explore associations with clinical severity found MD might differentiate injury severity in the acute setting and be worthy of development as an imaging biomarker.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 31, 2020
2020 journal article
Infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) mass spectrometry imaging analysis of endogenous metabolites in cherry tomatoes
ANALYST, 145(16), 5516–5523.
MeSH headings : Lasers; Lipids; Solanum lycopersicum; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
TL;DR:
The spatially resolved metabolic profiling of cherry tomatoes using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI), a mass spectrometry imaging technique that operates at ambient conditions and requires no sample derivatization, finds endogenous carotenoid hydrocarbons ionized as radical cations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 31, 2020
2020 journal article
Direct Analysis of Native N-Linked Glycans by IR-MALDESI
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 31(8), 1759–1762.
author keywords: IR-MALDESI; N-linked glycans; glycomics; direct analysis
TL;DR:
This study sought to demonstrate infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) as a novel approach for the direct analysis of N-linked glycans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 31, 2020
2020 journal article
Nairobi Sheep Disease Virus: A Historical and Epidemiological Perspective
FRONTIERS IN VETERINARY SCIENCE, 7.
Contributors: S. Krasteva n, M. Jara n, A. Frias-De-Diego n & G. Machado n
author keywords: ecological niche model; systematic review; spatial distribution; small ruminants; tick-borne; disease surveillance
TL;DR:
It is critical to investigate the epidemiology of NSDv in order to promote better allocation of resources to control its spread in regions that are more at risk, as climate change will favor emergence of such vector-borne diseases in areas with dense small ruminant populations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 31, 2020
2020 article
Ultrasound findings in tendons and ligaments of lame sport horses competing or training in South Florida venues during the winter seasons of 2007 through 2016
EQUINE VETERINARY EDUCATION.
author keywords: horse; sport horse; lameness; ultrasonography; suspensory ligament; inferior check ligament; superficial and deep digital flexor tendons
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 25, 2020
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