Works Published in 2021
Displaying works 81 - 100 of 100 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2021 article
Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation
Ferrara, F., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
doi.org (publisher)
Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021
2021 journal article
Cell Wall Polysaccharide Composition of Grafted 'Liberty' Watermelon With Reduced Incidence of Hollow Heart Defect
FRONTIERS IN PLANT SCIENCE, 12.
author keywords: Citrullus lanatus; watermelon; neutral sugar; graft; linkage assembly; pectin
TL;DR:
Grafting onto the interspecific hybrid rootstock decreased the incidence of HH and can be a useful method for growers using HH susceptible cultivars, including the identification of several new linkages.
(via Semantic Scholar)
Source: Web Of Science
Added: April 5, 2021
2021 journal article
Cutaneous antimicrobial peptides: New “actors” in pollution related inflammatory conditions
Redox Biology, 41, 101952.
author keywords: Skin; LL37; ROS; Antimicrobial peptides; Pollution
MeSH headings : Humans; Hydrogen Peroxide; Keratinocytes; Pore Forming Cytotoxic Proteins; Skin; Skin Diseases
TL;DR:
Exposure to O3 is hypothesized to contribute to various cutaneous inflammatory conditions, such as eczema, psoriasis, rush etc via a redox-inflammatory pathway and altered levels of AMPs are observed, suggesting that targeting AMPs could be a possible defensive strategy to combat pollution-associated skin conditions.
(via Semantic Scholar)
Source: ORCID
Added: April 1, 2021
2021 journal article
Impaired mitochondrial quality control in Rett Syndrome
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 700.
author keywords: RTT Syndrome; Oxidative stress; Mitochondrial quality control; Mitophagy; Apoptosis
MeSH headings : Adolescent; Adult; Apoptosis; Caspase 3 / genetics; Caspase 3 / metabolism; Caspase 7 / genetics; Caspase 7 / metabolism; Child; Dynamins / genetics; Dynamins / metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; GTP Phosphohydrolases / genetics; GTP Phosphohydrolases / metabolism; Humans; Membrane Proteins / genetics; Membrane Proteins / metabolism; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mitochondria / genetics; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Membrane Transport Proteins / genetics; Mitochondrial Membrane Transport Proteins / metabolism; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Mitophagy; Oxidation-Reduction; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology
TL;DR:
It is shown that RTT fibroblasts have networks of hyperfused mitochondria with morphological abnormalities and increased mitochondrial volume, shedding light on new aspects of mitochondrial dysfunction in RTT that are represented by defective mitochondrial QC pathways, providing new potential targets for a therapeutic intervention aimed at slowing down clinical course and manifestations in the affected patients.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 15, 2021
2021 review
Connection between the Altered HDL Antioxidant and Anti-Inflammatory Properties and the Risk to Develop Alzheimer's Disease: A Narrative Review
[Review of ]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021.
MeSH headings : Alzheimer Disease / etiology; Alzheimer Disease / metabolism; Alzheimer Disease / pathology; Animals; Anti-Inflammatory Agents / metabolism; Antioxidants / metabolism; Humans; Inflammation / complications; Lipoproteins, HDL / metabolism; Oxidative Stress
TL;DR:
This review summarized and critically analyzed the most significant findings linking HDL accessory proteins and AD and discusses the most convincing hypothesis explaining the mechanism by which an observed systemic occurrence may have repercussions in the brain.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 22, 2021
2021 journal article
Circadian Deregulation as Possible New Player in Pollution-Induced Tissue Damage
ATMOSPHERE, 12(1).
author keywords: circadian clock; pollution; antioxidant system
TL;DR:
It is hypothesized that chronodistruption can exacerbate cell vulnerability to exogenous damaging agents, and a possible common mechanism of action in deregulation of the homeostasis of the pulmonary, cardiovascular and cutaneous tissues and in its involvement in the development of pathological conditions is suggested.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021
2021 journal article
Whey protein-polyphenol aggregate particles mitigate bar hardening reactions in high protein bars
LWT-FOOD SCIENCE AND TECHNOLOGY, 138.
author keywords: Protein bar; Texture; Polyphenol; Particle; Microstructure
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021
2021 journal article
An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder
SCIENTIFIC REPORTS, 11(1).
MeSH headings : Animals; Disease Models, Animal; Female; Fetal Alcohol Spectrum Disorders / blood; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / microbiology; Gastrointestinal Microbiome; Male; Mice; Mothers; Pregnancy
TL;DR:
The maternal microbiome and its MDPs are a previously unrecognized influence upon the pathologies that typify PAE, and are concluded to constitute a characteristic biosignature that distinguishes PAE.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 10, 2021
2021 journal article
Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro.
Nutrition and Cancer.
MeSH headings : Animals; Chromatography, Liquid; Gastrointestinal Microbiome; Polyphenols / analysis; Rats; Tandem Mass Spectrometry; Urinary Bladder Neoplasms / drug therapy
TL;DR:
It is suggested that microbial metabolites may be the primary compounds responsible for chemoprevention in uroepithelial cell following flavanol consumption, highlighting the potential for exploiting knowledge about individual genetics, microbiome profiles, flavonoid metabolism profiles, tumor characteristics, etc. to design personalized dietary interventions for cancer prevention and/or adjuvant therapy to reduce bladder cancer incidence and improve outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: February 10, 2021
2021 journal article
Rheum rhaponticum Root Extract Improves Vasomotor Menopausal Symptoms and Estrogen-Regulated Targets in Ovariectomized Rat Model
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(3).
Contributors: M. Wilson n, V. Konda*, K. Heidt n, T. Rathinasabapathy n , A. Desai* & S. Komarnytsky n
author keywords: postmenopausal; estrogens; hot flashes; HRT; ERr 731
MeSH headings : Animals; Biomarkers; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / metabolism; Hot Flashes; Menopause / drug effects; Molecular Structure; Ovariectomy; Phytoestrogens / chemistry; Phytoestrogens / pharmacology; Plant Extracts / chemistry; Plant Extracts / pharmacology; Plant Roots / chemistry; Postmenopause; Rats; Rheum / chemistry; Vasomotor System / drug effects
TL;DR:
Data validate the OVX/Tskin rat model as a suitable screening platform to evaluate botanical and pharmaceutical treatments of menopause, while providing further evidence for the efficacy of ERr 731 towards alleviating vasomotor menopausal symptoms and improving wellbeing during the menopausal transition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 21, 2021
2021 journal article
Skeletal Protection and Promotion of Microbiome Diversity by Dietary Boosting of the Endogenous Antioxidant Response
JOURNAL OF BONE AND MINERAL RESEARCH, 36(4), 768–778.
author keywords: NUTRITION; GENETIC ANIMAL MODELS; SEX STEROIDS; OSTEOPOROSIS; THERAPEUTICS— OTHER
MeSH headings : Animals; Antioxidants; Bone and Bones; Diet; Female; Humans; Male; Mice; Microbiota; Phylogeny
TL;DR:
A blueberry cultivar that added to the diet protects female mice from musculoskeletal loss and body weight changes induced by ovariectomy and elicits antioxidant defense responses independently of classical antioxidant/estrogenic signaling, and increases gut microbiome diversity toward a healthier signature.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 19, 2021
2021 journal article
Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ, PWK/EiJ, CAST/PhJ, and WSB/EiJ mice
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 87.
author keywords: Natural products; Genetic diversity; Diabetes; Flavonoids; Personalized nutrition; Interindividual variation
MeSH headings : Animals; Anti-Obesity Agents / therapeutic use; Collaborative Cross Mice / genetics; Collaborative Cross Mice / physiology; Diet, High-Fat / adverse effects; Disease Models, Animal; Female; Genetic Variation; Male; Obesity / drug therapy; Obesity / etiology; Obesity / genetics; Quercetin / therapeutic use; Sex Factors
TL;DR:
How diverse mouse strains respond to diet-induced obesity when fed a representative flavonoid is explored to justify use of genetically diverse Collaborative Cross and Diversity Outbred models which are emerging as invaluable tools in the field of personalized nutrition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 11, 2021
2021 journal article
Storage of biofortified maize in Purdue Improved Crop Storage (PICS) bags reduces disulfide linkage-driven decrease in porridge viscosity
LWT-FOOD SCIENCE AND TECHNOLOGY, 136.
author keywords: Biofortified maize; Porridge; Viscosity; Purdue improved crops storage (PICS)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 11, 2021
2021 journal article
Phytoecdysteroids Do Not Have Anabolic Effects in Skeletal Muscle in Sedentary Aging Mice
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(2).
author keywords: skeletal muscle; hypertrophy; Akt; atrogenes; 20-hydroxyecdysone
MeSH headings : Aging; Anabolic Agents; Animals; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Rats
TL;DR:
Data indicate that phytoecdysteroid treatment does not alter muscle mass or fiber type, nor does it activate protein synthesis signaling in the skeletal muscle of sedentary aging mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 7, 2021
2021 journal article
Genome sequence of Monilinia vaccinii-corymbosi sheds light on mummy berry disease infection of blueberry and mating type
G3-GENES GENOMES GENETICS, 11(2).
Ed(s): D. Baltrus
author keywords: blueberry; mummy berry; Monilinia vaccinii-corymbosi; Mvc; disease; blight; pathology; mating-type; effectors
MeSH headings : Ascomycota / genetics; Blueberry Plants; Fruit; North America; Plant Diseases / microbiology
TL;DR:
In this study, PacBio sequencing and Hi-C interaction data were utilized to create a chromosome-scale reference genome for Mvc and the mating-type (MAT) locus was characterized, indicating the potential for homothallism in the reference genome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 5, 2021
2021 journal article
The same anthocyanins served four different ways: Insights into anthocyanin structure-function relationships from the wintergreen orchid, Tipularia discolor
PLANT SCIENCE, 303.
author keywords: Abaxial/adaxial anthocyanins; Acylated cyanidin; 3,7,3 '-Triglucoside; Camouflage; Chemotaxonomy; Leaf color evolution; Herbivory defense
MeSH headings : Anthocyanins / chemistry; Anthocyanins / isolation & purification; Anthocyanins / physiology; Chromatography, High Pressure Liquid; Color; Gas Chromatography-Mass Spectrometry; Microscopy; Orchidaceae / metabolism; Orchidaceae / ultrastructure; Plant Leaves / metabolism; Plant Leaves / ultrastructure; Structure-Activity Relationship
TL;DR:
The results showed that the same three cyanidin 3,7,3'-triglucosides, in similar concentrations and proportions, accounted for coloration in each of these cases, and served as a reminder that plants may employ the same anthocyanins in different anatomical locations to achieve a broad range of colors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 11, 2020
2021 review
Bench approaches to study the detrimental cutaneous impact of tropospheric ozone
[Review of ]. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 31(1), 137–148.
author keywords: Environmental pollution; Skin; 3D skin tissue model; Oxidative stress; Skin protection
MeSH headings : Air Pollutants / adverse effects; Air Pollutants / analysis; Cities; Humans; Lipid Peroxidation; Oxidative Stress; Ozone / adverse effects; Ozone / analysis; Skin / metabolism
TL;DR:
Having a better understanding of O 3 effects on skin barrier properties and stress responses could help the whole dermato-cosmetic industry to design innovative protective solutions and develop specific cosmetic regime to protect the skin of every citizen.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: November 24, 2020
2021 review
SARS-CoV-2 infection, COVID-19 pathogenesis, and exposure to air pollution: What is the connection?
[Review of ]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1486(1), 15–38.
author keywords: air pollution; coronavirus; particulate matter; ozone; nitrogen dioxide; viral infection
MeSH headings : Adaptive Immunity; Air Pollutants / adverse effects; Air Pollution / adverse effects; COVID-19 / etiology; COVID-19 / immunology; COVID-19 / virology; Host Microbial Interactions; Humans; Immunity, Innate; Models, Biological; Pandemics; Particulate Matter / adverse effects; Receptors, Virus / physiology; Respiratory System / physiopathology; SARS-CoV-2 / immunology; SARS-CoV-2 / pathogenicity; SARS-CoV-2 / physiology; Toll-Like Receptors / physiology; Virus Internalization; Virus Replication
TL;DR:
Air pollution exposure may affect different stages of the viral life cycle, including inhibition of mucociliary clearance, alteration of viral receptors and proteases required for entry, changes to antiviral interferon production and viral replication, changes in viral assembly mediated by autophagy, prevention of uptake by macrophages, and promotion of viral spread by increasing epithelial permeability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: October 19, 2020
2021 journal article
The gut microbiome-derived metabolite trimethylamineN-oxide modulates neuroinflammation and cognitive function with aging
GEROSCIENCE, 43(1), 377–394.
author keywords: Cognitive impairment; Inflammation; Astrocyte activation; Brain; Memory
MeSH headings : Aging; Animals; Cognition; Gastrointestinal Microbiome; Methylamines; Mice
TL;DR:
The results provide translational insight into a novel pathway that modulates neuro inflammation and cognitive function with aging, and suggest that TMAO might be a promising target for prevention of neuroinflammation and cognitive decline with aging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 14, 2020
2021 journal article
Protective effects of a comprehensive topical antioxidant against ozone-induced damage in a reconstructed human skin model
ARCHIVES OF DERMATOLOGICAL RESEARCH, 313(3), 139–146.
author keywords: Antioxidants; Ozone; Oxidative damage; Cosmeceuticals; Free radicals; Reactive Oxygen Species (ROS)
MeSH headings : Administration, Cutaneous; Antioxidants / administration & dosage; Cell Culture Techniques; Cells, Cultured; Drug Evaluation, Preclinical; Epidermis / drug effects; Epidermis / pathology; Humans; Lipid Peroxidation / drug effects; Oxidative Stress / drug effects; Ozone / adverse effects; Reactive Oxygen Species / metabolism; Skin Aging / drug effects
TL;DR:
A comprehensive topical antioxidant significantly diminished O 3 -induced oxidative damage in a human epidermal skin model and inhibited damage in tissues exposed to O 3 with no significant changes in epidermis structure.
(via Semantic Scholar)
Source: Web Of Science
Added: May 26, 2020
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
