Works Published in 2016
Displaying works 121 - 140 of 239 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Bone protein “extractomics”: comparing the efficiency of bone protein extractions of Gallus gallus in tandem mass spectrometry, with an eye towards paleoproteomics
PeerJ, 4, e2603.
author keywords: Bone matrix proteins; Bone protein extraction protocols; Methods comparison; Paleoproteomics; Mass spectrometry; Proteomics
TL;DR:
It is found that when a standardized amount of extracted proteins was analyzed, extraction steps that yielded the most protein were often not the ones that produced the greatest diversity of bone proteins, or the highest degree of protein coverage.
(via Semantic Scholar)
peerj.com (publisher PDF)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2016 journal article
Advancing toxicology research using in vivo high throughput toxicology with small fish models
ALTEX - Alternatives to Animal Experimentation, 33(4), 435–452.
Contributors: A. Planchart n , C. Mattingly n , D. Allen *, P. Ceger *, W. Casey *, D. Hinton *, J. Kanungo *, S. Kullman n
author keywords: aquatic models; 21st century toxicology; alternatives
TL;DR:
The recommendations formulated by workshop participants to enhance the utility of small fish species in toxicology studies are summarized, as well as many of the advances in the field of toxicology that resulted from usingSmall freshwater fish species, including advances in developmental toxicology, cardiovascular toxicologists, neurotoxicology, and immunotoxicology are reviewed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database
Environmental Health Perspectives, 124(10), 1592–1599.
Contributors: C. Grondin n, A. Davis n, T. Wiegers n, B. King *, J. Wiegers n, D. Reif n , J. Hoppin n , C. Mattingly n
TL;DR:
Curation and integration of exposure data within the CTD provides researchers with new opportunities to correlate exposures with human health outcomes, to identify underlying potential molecular mechanisms, and to improve understanding about the exposome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2016 journal article
Using toxcast™ data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure
Environmental Health Perspectives, 124(7), 910–919.
Contributors: I. Shah *, R. Woodrow Setzer*, J. Jack n, K. Houck *, R. Judson *, T. Knudsen *, J. Liu *, M. Martin*
MeSH headings : Environmental Pollutants / toxicity; High-Throughput Screening Assays; Membrane Potential, Mitochondrial; Risk Assessment; Toxicity Tests / methods
TL;DR:
These findings show the utility of HCI data for reconstructing cell state trajectories and provide insight into the adaptation and resilience of in vitro cellular systems based on tipping points.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2016 journal article
Transplacental and Lactational Transfer of Firemaster (R) 550 Components in Dosed Wistar Rats
TOXICOLOGICAL SCIENCES, 153(2), 246–257.
author keywords: Firemaster 550; lactational transfer; gestational transfer; metabolites; rodent
MeSH headings : Animals; Dose-Response Relationship, Drug; Female; Flame Retardants / pharmacokinetics; Lactation; Male; Maternal-Fetal Exchange; Placenta / metabolism; Pregnancy; Rats; Rats, Wistar
TL;DR:
This study is the first to confirm ip-PPP as a urinary metabolite of ITPs and establish a pharmacokinetic profile of FM 550 in a mammalian model.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Quantitative trait loci influencing forking defects in an outbred pedigree of loblolly pine
BMC GENETICS, 17.
author keywords: QTL; Stem forking; Outbred; Pinus taeda; MAS; Tree breeding; Wood quality
MeSH headings : Algorithms; Breeding; Chromosome Mapping; Genetic Association Studies; Genetic Linkage; Genetic Markers; Genotype; Models, Statistical; Pedigree; Phenotype; Pinus taeda / genetics; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Quantitative Trait, Heritable
TL;DR:
The hypothesis that marker-assisted selection can be used to decrease the rate of stem defects in breeding populations of loblolly pine is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Physiological, ecological, and behavioural correlates of the size of the geographic ranges of sea kraits (Laticauda; Elapidae, Serpentes): A critique
JOURNAL OF SEA RESEARCH, 115, 18–25.
author keywords: Sea kraits; Distribution; Temperature; Salinity
TL;DR:
Re-assessment of the relationships of temperature and salinity as determinants of the size of the geographic ranges of sea kraits resolved the paradox of lack of correspondence of size of range with degree of terrestrialism, but did not form a definitive test of the theory.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Mitochondrial Genome Sequences and Structures Aid in the Resolution of Piroplasmida phylogeny
PLOS ONE, 11(11).
MeSH headings : DNA, Protozoan / genetics; Genome, Mitochondrial; Humans; Phylogeny; Piroplasmida / classification; Piroplasmida / genetics; Protozoan Infections / parasitology
TL;DR:
Phylogenetic analysis of concatenated mitochondrial and 18S sequences as well as cox1 amino acid sequence identified five distinct Piroplasmida groups, each of which possesses a unique mitochondrial genome structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Interaction of bisphenol A (BPA) and soy phytoestrogens on sexually dimorphic sociosexual behaviors in male and female rats
HORMONES AND BEHAVIOR, 84, 121–126.
author keywords: Endocrine disruption; Neuroendocrine disruption; Neuropeptides; Social; Diet; Open field; Affiliation; Activity; Environment
MeSH headings : Animals; Benzhydryl Compounds / pharmacology; Endocrine Disruptors / pharmacology; Exploratory Behavior / drug effects; Female; Isoflavones / pharmacology; Male; Phenols / pharmacology; Phytoestrogens / pharmacology; Rats; Sexual Behavior, Animal / drug effects; Social Behavior
TL;DR:
Testing the individual and combined effects of low dose oral BPA and soy diet or the individual isoflavone genistein on rat sociosexual behaviors with the hypothesis that soy would obfuscate any BPA-related effects reinforces that environmental factors can shape complex behaviors and even reverse expected sex differences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
High-throughput Cryopreservation of Sperm from Sex-reversed Southern Flounder, Paralichthys lethostigma
JOURNAL OF THE WORLD AQUACULTURE SOCIETY, 47(4), 555–565.
TL;DR:
A protocol was developed for sperm cryopreservation in the Southern flounder with high-throughput processing, which provides a tool to preserve the valuable genetic resources from neomale flounders, and enables germplasm repository development for the SouthernFlounder.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation
PLOS GENETICS, 12(7).
MeSH headings : Amino Acid Motifs; Animals; Binding Sites; Biological Evolution; DNA / chemistry; DNA-Binding Proteins / genetics; Dinucleotide Repeats; Dosage Compensation, Genetic; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Female; Gene Dosage; Genes, X-Linked; Genetic Linkage; Genome, Insect; Male; Oligonucleotide Array Sequence Analysis; Sequence Analysis, DNA; X Chromosome / genetics
TL;DR:
It is revealed that expansion of GA-dinucleotide repeats likely accumulated on the X-chromosome over evolutionary time to increase the density of CLAMP binding sites, thereby driving the evolution of dosage compensation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Evaluating monitoring methods for cetaceans
BIOLOGICAL CONSERVATION, 201, 252–260.
author keywords: Power analysis; Sampling effort; Hawaii spinner dolphins; Stenella longirostris; Human pressures; Individual identification
TL;DR:
A systematic and rigorous sampling regime was developed to estimate abundance of a small, genetically isolated spinner dolphin population exposed to high levels of human activities, applicable across taxa for which individuals can be identified, including terrestrial and aquatic mammals, birds, and reptiles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes
METABOLOMICS, 12(11).
Contributors: C. Scott Chialvo *, R. Che n, D. Reif n , A. Motsinger-Reif n & L. Reed *
author keywords: Eigenvector metabolite analysis; Linkage analyses; Environment; Enrichment analyses
TL;DR:
Eigenvector Metabolite Analysis provides a simple method to identify correlations between metabolites, gene expression, and phenotypes, which can allow us to partition multivariate datasets into meaningful biological modules and identify under-studied metabolites and unannotated gene transcripts that may be central to important biological processes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Dengue virus NS1 enhances viral replication and pro-inflammatory cytokine production in human dendritic cells
VIROLOGY, 496, 227–236.
author keywords: Dengue; NS1; Nonstructural protein NS1; Dendritic cells; Proinflammatory cytokines; Immune modulation
MeSH headings : Cells, Cultured; Cytokines / biosynthesis; Dendritic Cells / immunology; Dendritic Cells / metabolism; Dendritic Cells / virology; Dengue / immunology; Dengue / metabolism; Dengue / virology; Dengue Virus / classification; Dengue Virus / physiology; Humans; Immunomodulation; Inflammation Mediators / metabolism; Serogroup; Viral Nonstructural Proteins / metabolism; Virus Replication
TL;DR:
The presence of exogenous NS1 is able to modulate dengue infection in mo-DCs and produced more pro-inflammatory cytokines in response to subsequent DV infection compared to DCs exposed to heat-inactivated NS1 (HNS1).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
13. Climate Action
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Can't take the heat: Temperature-enhanced toxicity in the mayfly Isonychia bicolor exposed to the neonicotinoid insecticide imidacloprid
AQUATIC TOXICOLOGY, 178, 49–57.
author keywords: Neonicotinoids; Imidacloprid; Aquatic invertebrates; Temperature; Toxicity; Physiology
MeSH headings : Animals; Aquatic Organisms / drug effects; Aquatic Organisms / metabolism; Behavior, Animal / drug effects; Dose-Response Relationship, Drug; Environmental Monitoring / methods; Ephemeroptera / drug effects; Ephemeroptera / metabolism; Hot Temperature; Imidazoles / toxicity; Insecticides / toxicity; Neonicotinoids; Nitro Compounds / toxicity; Toxicity Tests, Acute; Water Pollutants, Chemical / toxicity
TL;DR:
It is demonstrated that temperature is a powerful modulator of sublethal toxicity within a range of environmentally relevant temperatures, impacting both uptake rates and metabolic rates of I. bicolor and shows that temperature alters imidacloprid uptake across arange of species, highlighting the physiological variation present within aquatic invertebrate communities and the challenge associated with relying solely on surrogate species.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 personal communication
Build habitats, not fences, for caribou
Proulx, G., & Powell, R. A. (2016, September 30).
MeSH headings : Animals; Ecosystem; Reindeer
TL;DR:
A proposed 50-year-long project to create a predator-free, fenced, 100-square-kilometer landscape to farm caribou in the Little Smoky range intends to kill.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Bony cranial ornamentation linked to rapid evolution of gigantic theropod dinosaurs
Nature Communications, 7(1).
TL;DR:
It is found that body size evolved directionally toward phyletic giantism an order of magnitude faster in theropod species possessing ornaments compared with unadorned lineages, and there is novel, quantitative support for a shift in selective pressures on socio-sexual display mechanisms in the theropods coincident with the evolution of pennaceous feathers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2016 journal article
ToxEvaluator: an integrated computational platform to aid the interpretation of toxicology study-related findings
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.
MeSH headings : Animals; Computational Biology / methods; Computer Simulation; Database Management Systems; Databases, Factual; Humans; Mice; Toxicogenetics / methods; User-Computer Interface
TL;DR:
ToxEvaluator was developed jointly by Pfizer and the Comparative Toxicogenomics Database as an in silico platform to facilitate interpretation of toxicity findings in light of prior knowledge and rapidly identified direct and indirect linkages between cerivastatin and myopathy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 review
Salinized rivers: degraded systems or new habitats for salt-tolerant faunas?
[Review of ]. BIOLOGY LETTERS, 12(3).
author keywords: major ions; salinity; freshwater; novel ecosystems; osmoregulation; adaptation
MeSH headings : Animals; Biodiversity; Ecosystem; Insecta / physiology; Rivers / chemistry; Salinity
TL;DR:
A conceptual framework predicting how communities may change in salinizing rivers is outlined, envisioning that a relatively small number of taxa will be saline-tolerant and able to colonize salinized rivers, leading to depauperate communities in these environments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 review
Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast (TM) High-Throughput Data
[Review of ]. ENVIRONMENTAL HEALTH PERSPECTIVES, 124(8), 1141–1154.
Contributors: S. Auerbach *, D. Filer*, D. Reif n , V. Walker *, A. Holloway *, J. Schlezinger *, S. Srinivasan *, D. Svoboda*
MeSH headings : Databases, Factual; Diabetes Mellitus / chemically induced; Diabetes Mellitus / epidemiology; Environment; Environmental Exposure / statistics & numerical data; Environmental Pollutants / standards; Environmental Pollutants / toxicity; High-Throughput Screening Assays; Humans; Obesity / chemically induced; Obesity / epidemiology; Outcome Assessment, Health Care; Risk Assessment; United States; United States Environmental Protection Agency
TL;DR:
The results of this screening-level analysis suggest that the spectrum of environmental chemicals to consider in research related to diabetes and obesity is much broader than indicated by research papers and reviews published in the peer-reviewed literature.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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