Works Published in 2018

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Displaying works 181 - 200 of 301 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

Multiloculated solitary (unicameral) bone cyst in a young dog

VETERINARY CLINICAL PATHOLOGY, 47(3), 484–488.

By: S. Roode n, H. Shive n, W. Hoorntje n, J. Bernard*, D. Stowe n, R. Pool*, C. Grindem n

author keywords: Canine; cytology; lytic; osseous; osteoclast; skeletal
MeSH headings : Animals; Bone Cysts / complications; Bone Cysts / diagnostic imaging; Bone Cysts / pathology; Bone Cysts / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Female; Femur / diagnostic imaging; Femur / pathology; Lameness, Animal / etiology; Lameness, Animal / pathology; Radiography / veterinary
TL;DR: A 20-month-old female spayed Staffordshire Terrier presented to the Orthopedic Surgery Service at North Carolina State University Veterinary Teaching Hospital for evaluation of a 6-week history of toe-touching to nonweight-bearing lameness, and amputation of the right hind limb was performed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Serotype survey of AAV gene delivery via subconjunctival injection in mice

Gene Therapy, 25(6), 402–414.

By: L. Song*, T. Llanga*, L. Conatser*, V. Zaric*, B. Gilger n & M. Hirsch*

MeSH headings : Animals; Conjunctiva / pathology; Cornea / metabolism; Cornea / pathology; Cornea / virology; Dependovirus / genetics; Eye Diseases / genetics; Eye Diseases / pathology; Eye Diseases / therapy; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors / genetics; Genetic Vectors / immunology; Green Fluorescent Proteins / genetics; Humans; Mice; Serogroup; Surveys and Questionnaires; Transduction, Genetic
TL;DR: Subconjunctival administration of particular AAV serotypes may be a simple and safe targeted gene delivery route for ocular surface, muscular, corneal, and optic nerve diseases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: October 16, 2018

2018 journal article

Evaluation of digital cryotherapy using a commercially available sleeve style ice boot in healthy horses and horses receiving i.v. endotoxin

EQUINE VETERINARY JOURNAL, 50(6), 848–853.

By: M. Burke n, J. Tomlinson*, A. Blikslager n, A. Johnson* & B. Dallap-Schaer*

author keywords: horse; digital cryotherapy; sepsis-associated laminitis; sleeve-style ice boot; lamellar temperatures
MeSH headings : Animals; Cross-Over Studies; Cryotherapy / instrumentation; Cryotherapy / standards; Cryotherapy / veterinary; Endotoxins / administration & dosage; Endotoxins / blood; Female; Foot Diseases / therapy; Foot Diseases / veterinary; Forelimb; Hoof and Claw / pathology; Horse Diseases / therapy; Horses; Male; Prospective Studies; Random Allocation; Skin Temperature
TL;DR: This study is the first to show that a sleeve style boot, where ice does not cover the hoof, can cause significant decreases in lamellar temperatures through cooling of blood as it travels to the foot. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 16, 2018

2018 journal article

The Salmonella type-3 secretion system-1 and flagellar motility influence the neutrophil respiratory burst

PLOS ONE, 13(9).

MeSH headings : Fimbriae, Bacterial / physiology; Genotype; Granulocyte-Macrophage Colony-Stimulating Factor / pharmacology; Humans; Interleukin-8 / pharmacology; Neutrophils / cytology; Neutrophils / metabolism; Neutrophils / microbiology; Reactive Oxygen Species / metabolism; Respiratory Burst / drug effects; Salmonella / genetics; Salmonella / metabolism; Type III Secretion Systems / drug effects; Type III Secretion Systems / metabolism
TL;DR: It is demonstrated that both the type-3 secretion system-1 and flagellar motility, which are established virulence factors in enteric salmonellosis, also appear to directly influence the magnitude of the neutrophil respiratory burst in response to STm in vitro. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

2018 journal article

Toxicity associated with ingestion of a polyacrylic acid hydrogel dog pad

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 30(5), 708–714.

author keywords: Dogs; hydrogel; neurotoxicity; poisoning; sodium polyacrylate
MeSH headings : Acrylic Resins / poisoning; Acrylic Resins / toxicity; Animals; Dog Diseases / chemically induced; Dogs; Eating; Female; Hydrogels / poisoning; Hydrogels / toxicity; Male; North Carolina; Rats; Rats, Sprague-Dawley
TL;DR: Results from an experimental study in rats support the conclusion that some pet pad hydrogel products can induce acute neurotoxicity in animals under high-dose exposure conditions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018

2018 journal article

Enrichment Preferences of FIV-Infected and Uninfected Laboratory-Housed Cats

Viruses, 10(7), 353.

By: C. Kennedy n, A. Thomson*, E. Griffith n, J. Fogle n, B. Lascelles, R. Meeker*, B. Sherman*, M. Gruen*

author keywords: FIV; enrichment; welfare; feline; laboratory animal
MeSH headings : Animals; Animals, Laboratory; Cats; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / physiology
TL;DR: Cats used in a longitudinal study of the effects of chronic feline immunodeficiency virus (FIV) infection were used and it was found that cats elected to be brushed, preferred social interaction and play with the laser to the ball, and preferred to scratch on an inclined-box toenail conditioning object compared to a horizontal, circular toenails conditioning object. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: October 16, 2018

2018 journal article

Dogs with acute myeloid leukemia or lymphoid neoplasms (large cell lymphoma or acute lymphoblastic leukemia) may have indistinguishable mediastinal masses on radiographs

VETERINARY RADIOLOGY & ULTRASOUND, 59(5), 507–515.

author keywords: hematopoietic neoplasia; immunophenotyping; myeloid sarcoma; thorax
MeSH headings : Animals; Cross-Sectional Studies; Dog Diseases / diagnostic imaging; Dog Diseases / etiology; Dogs; Female; Leukemia, Myeloid, Acute / diagnostic imaging; Leukemia, Myeloid, Acute / etiology; Leukemia, Myeloid, Acute / veterinary; Lymphoma, Non-Hodgkin / diagnostic imaging; Lymphoma, Non-Hodgkin / etiology; Lymphoma, Non-Hodgkin / veterinary; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnostic imaging; Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology; Precursor Cell Lymphoblastic Leukemia-Lymphoma / veterinary; Radiography; Retrospective Studies
TL;DR: In conclusion, acute myeloid leukemia should be considered when a mediastinal mass is detected during radiography in dogs with suspected hematopoietic neoplasia-but the presence or size of a mediastsinal mass does not differentiate between myeloids and lymphoid neoplasms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

2018 journal article

Cardiorespiratory interactions in the Pacific spiny dogfish, Squalus suckleyi

JOURNAL OF EXPERIMENTAL BIOLOGY, 221(17).

By: N. Acharya-Patel*, C. Deck n & W. Milsom*

author keywords: Cardiorespiratory synchrony; Dogfish; Hypoxia; Hyperoxia; Heart rate variability; Vagus nerve
MeSH headings : Anaerobiosis; Animals; Heart Rate / physiology; Oxygen / metabolism; Respiratory Rate / physiology; Seawater / chemistry; Squalus / physiology; Vagus Nerve / physiology
TL;DR: In Pacific spiny dogfish, cardiorespiratory synchrony only occurs during progressive hyperoxia post-atropine, when heart rate is uninhibited and ventilation is slowed owing to the increase in available oxygen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Pharmacokinetics and pharmacodynamic effects in koi carp (Cyprinus carpio) following immersion in propofol

VETERINARY ANAESTHESIA AND ANALGESIA, 45(4), 529–538.

By: A. Oda n, K. Messenger n, L. Carbajal n, L. Posner n, B. Gardner n, S. Hammer n, A. Cerreta n, G. Lewbart n, K. Bailey n

author keywords: fish; immersion; koi carp; pharmacodynamics; pharmacokinetics; propofol
MeSH headings : Anesthesia Recovery Period; Animals; Carps / metabolism; Chromatography, High Pressure Liquid / veterinary; Deep Sedation / methods; Deep Sedation / veterinary; Heart Rate / drug effects; Hypnotics and Sedatives / administration & dosage; Hypnotics and Sedatives / blood; Hypnotics and Sedatives / pharmacokinetics; Hypnotics and Sedatives / pharmacology; Immersion; Propofol / administration & dosage; Propofol / blood; Propofol / pharmacokinetics; Propofol / pharmacology
TL;DR: Measurable PPCs were achieved in koi carp anesthetized with propofol by immersion, but recovery time was not. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

2018 journal article

Readability Evaluations of Veterinary Client Handouts and Implications for Patient Care

TOPICS IN COMPANION ANIMAL MEDICINE, 33(2), 58–61.

author keywords: assessment; clinical science; communications; diversity; practice/business management; public health
MeSH headings : Animals; Health Literacy / standards; Humans; Patient Care / methods; Patient Care / veterinary; Patient Education as Topic / methods; Patient Education as Topic / standards; Reading; Veterinary Medicine / methods
TL;DR: Evaluating the readability levels of a sample of popular client handout materials prepared expressly for veterinarians to download and distribute to their pet-owning clients indicates that 9 of 10 client brochures were written above the recommended sixth grade reading level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 16, 2018

2018 journal article

Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair

PLOS ONE, 13(8), e0200674.

Ed(s): J. Karhausen

MeSH headings : Animals; Animals, Newborn; Cells, Cultured; Epithelium / injuries; Epithelium / pathology; Intestinal Diseases / physiopathology; Intestinal Mucosa / cytology; Intestinal Mucosa / physiology; Ischemia / physiopathology; Jejunum / injuries; Jejunum / physiology; Recovery of Function; Swine; Vascular Diseases / pathology; Vascular Diseases / prevention & control
TL;DR: Findings support the hypothesis that a defect in mucosal repair in neonates is due to immature repair mechanisms within the mucosal compartment, and ex vivo exogenous application of injured juvenile mucosal homogenate produced a significant increase in TEER and enhanced histological restitution. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: October 16, 2018

2018 journal article

Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia

Journal of Visualized Experiments, 5(135).

By: A. Stieler Stewart, J. Freund*, A. Blikslager* & L. Gonzalez*

author keywords: Medicine; Issue 135; Porcine; intestine; ischemia-reperfusion; stem cell; enteroid; organoid
MeSH headings : Animals; Cell Culture Techniques / methods; Disease Models, Animal; Humans; Intestine, Small / cytology; Intestine, Small / metabolism; Intestine, Small / pathology; Ischemia / etiology; Mice; Stem Cells / metabolism; Swine
TL;DR: By utilizing a porcine model, a protocol is established in which segmental loops of intestinal ischemia can be created within a single animal, enabling the study of differing time points of ischemic injury and repair in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: October 16, 2018

2018 journal article

Single fraction stereotactic radiation therapy (stereotactic radiosurgery) is a feasible method for treating intracranial meningiomas in dogs

VETERINARY RADIOLOGY & ULTRASOUND, 59(5), 632–638.

By: K. Kelsey n, T. Gieger n & M. Nolan n

author keywords: brain tumor; intracalvarial; radiosurgery; radiotherapy; stereotactic radiosurgery
MeSH headings : Animals; Brain Neoplasms / radiotherapy; Dog Diseases / radiotherapy; Dogs; Female; Infratentorial Neoplasms / radiotherapy; Infratentorial Neoplasms / veterinary; Male; Meningeal Neoplasms / radiotherapy; Meningeal Neoplasms / veterinary; Meningioma / radiotherapy; Meningioma / veterinary; Pilot Projects; Radiosurgery / methods; Radiosurgery / veterinary; Retrospective Studies; Treatment Outcome
TL;DR: Findings supported the use of stereotactic radiosurgery as an alternative method for treating dogs with presumed intracranial meningiomas, and there were no factors identified which were predictive of acute adverse event. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

2018 journal article

Dosing Regimen of Enrofloxacin Impacts Intestinal Pharmacokinetics and the Fecal Microbiota in Steers

FRONTIERS IN MICROBIOLOGY, 9.

author keywords: antimicrobial resistance; fluoroquinolone; cattle; microbiome; pharmacokinetics
TL;DR: Both dosing regimens of enrofloxacin achieve high concentrations in the intestinal lumen, and the rapid elimination mitigates long-term impacts on fecal E. coli resistance and the microbiota. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 16, 2018

2018 personal communication

Caudal intercostal block for abdominal surgery in horses

Gingold, B. M. C., Hassen, K. M., Milloway, M. C., Gerard, M., & Fowler, A. W. (2018, August).

MeSH headings : Anesthesia, Caudal / methods; Anesthesia, Caudal / veterinary; Animals; Horses / surgery; Intercostal Nerves; Laparotomy / veterinary; Nerve Block / veterinary; Pain, Postoperative / prevention & control; Pain, Postoperative / veterinary; Treatment Outcome
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Pharmacokinetics, pharmacodynamics and clinical use of trazodone and its active metabolite m-chlorophenylpiperazine in the horse

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 41(3), 393–401.

By: J. Davis*, J. Schirmer n & E. Medlin n

author keywords: adverse drug reaction; equine; sedative; serotonin antagonist and reuptake inhibitor
MeSH headings : Administration, Oral; Animals; Anti-Anxiety Agents / administration & dosage; Anti-Anxiety Agents / pharmacokinetics; Anti-Anxiety Agents / pharmacology; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Half-Life; Horses / blood; Male; Piperazines / administration & dosage; Piperazines / pharmacokinetics; Piperazines / pharmacology; Serotonin Receptor Agonists / administration & dosage; Serotonin Receptor Agonists / pharmacokinetics; Serotonin Receptor Agonists / pharmacology; Trazodone / administration & dosage; Trazodone / pharmacokinetics; Trazodone / pharmacology
TL;DR: Trazodone was successful in modifying behavioural problems to some degree in 17 of 18 clinical cases and Tolerance and subsequent lack of drug effect occurred in two of 18clinical cases following 14 or 21 days of use. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Treatment of carprofen overdose with therapeutic plasma exchange in a dog

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 28(4), 356–360.

By: A. Kjaergaard*, J. Davis n & M. Acierno*

author keywords: canine; kidney injury; NSAID toxicity; plasmapheresis
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / poisoning; Carbazoles / poisoning; Diagnosis, Differential; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Drug Overdose / diagnosis; Drug Overdose / therapy; Drug Overdose / veterinary; Female; Plasma Exchange / veterinary
TL;DR: Although recent studies suggest that this particular dog may not have received a toxic dose, a 51% reduction of plasma carprofen concentration was achieved over 180 minutes, and TPE may be beneficial for treatment of dogs that have ingested higher doses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2018 journal article

The pharmacokinetics and analgesic effects of extended-release buprenorphine administered subcutaneously in healthy dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 41(4), 502–512.

By: M. Barletta*, S. Ostenkamp n, A. Taylor n, J. Quandt*, B. Lascelles n & K. Messenger n

author keywords: buprenorphine; dog; extended-release; pharmacodynamics; pharmacokinetics
MeSH headings : Analgesia / methods; Analgesia / veterinary; Analgesics, Opioid / administration & dosage; Analgesics, Opioid / blood; Analgesics, Opioid / pharmacokinetics; Analgesics, Opioid / pharmacology; Animals; Buprenorphine / administration & dosage; Buprenorphine / blood; Buprenorphine / pharmacokinetics; Buprenorphine / pharmacology; Delayed-Action Preparations; Dogs; Female; Injections, Subcutaneous / veterinary; Male
TL;DR: Results showed that ER-buprenorphine administered at a dose of 0.2 mg/kg resulted in prolonged and sustained plasma concentrations and antinociceptive effects up to 72 hr after drug administration. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Supplementation of Maternal Diets with Docosahexaenoic Acid and Methylating Vitamins Impacts Growth and Development of Fetuses from Malnourished Gilts

CURRENT DEVELOPMENTS IN NUTRITION, 2(3).

author keywords: choline; B-vitamins; epigenetics; intrauterine growth restriction; nutrient restriction; low birth weight
TL;DR: Despite the mobilization of maternal stores, malnourished litters displayed reduced brain development that was fully mitigated by micronutrient supplementation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Stereotactic body radiation therapy for heart-base tumors in six dogs

JOURNAL OF VETERINARY CARDIOLOGY, 20(3), 186–197.

By: L. Magestro n, T. Gieger n & M. Nolan n

author keywords: Aortic body tumor; Chemodectoma; Radiosurgery
MeSH headings : Animals; Aorta; Dog Diseases / radiotherapy; Dogs; Female; Heart Neoplasms / radiotherapy; Heart Neoplasms / veterinary; Male; Paraganglioma, Extra-Adrenal / radiotherapy; Paraganglioma, Extra-Adrenal / veterinary; Radiosurgery / veterinary; Retrospective Studies; Treatment Outcome
TL;DR: SBRT is a potentially useful treatment but may not be appropriate for dogs with incidentally diagnosed, slowly growing tumors, which are not causing cardiovascular disturbances, and jet ventilation effectively reduced treatment delivery times. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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