Works Published in 2005

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Displaying works 61 - 80 of 91 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2005 journal article

Effect of in vivo jet fuel exposure on subsequent in vitro dermal absorption of individual aromatic and aliphatic hydrocarbon fuel constituents

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 68(9), 719–737.

MeSH headings : Animals; Female; Hydrocarbons / pharmacokinetics; Hydrocarbons / pharmacology; Permeability / drug effects; Skin Absorption / drug effects; Swine
TL;DR: It is suggested that the preexposure of skin to jet fuel enhances the subsequent in vitro percutaneous absorption of HC, so single-dose absorption data for jet fuel HC from naive skin may not be optimal to predict the toxic potential for repeated exposures. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Assessing organic contaminants in fish: Comparison of a nonlethal tissue sampling technique to mobile and stationary passive sampling devices

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 39(19), 7601–7608.

MeSH headings : Adipose Tissue / chemistry; Animals; Body Burden; Catfishes / metabolism; Environmental Monitoring / instrumentation; Environmental Monitoring / methods; Environmental Monitoring / statistics & numerical data; Muscle, Skeletal / chemistry; North Carolina; Pesticides / analysis; Polychlorinated Biphenyls / analysis; Water Pollutants, Chemical / analysis
TL;DR: Investigation of two novel methods for estimating organic contaminants in fish demonstrated for the first time that organic contaminant concentrations in adipose fin were highly correlated with muscle fillet concentrations, indicating that the adipose fins of certain fishes may be used to accurately estimate tissue concentrations without the need for lethal sampling. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna

AQUATIC TOXICOLOGY, 74(3), 193–204.

By: H. Wang n, A. Olmstead n, H. Li n & G. LeBlanc n

author keywords: endocrine disruptors; screening; juvenoids; sex determination
MeSH headings : Animals; Benzhydryl Compounds; Daphnia / drug effects; Daphnia / metabolism; Ecdysteroids / metabolism; Ecdysteroids / pharmacology; Endocrine System / drug effects; Endpoint Determination / methods; Fatty Acids, Unsaturated / pharmacology; Female; Juvenile Hormones / agonists; Juvenile Hormones / antagonists & inhibitors; Juvenile Hormones / metabolism; Male; Methoprene / pharmacology; Pesticides / toxicity; Phenols / toxicity; Phytol / pharmacology; Pyridines / pharmacology; Reproducibility of Results; Sex Differentiation / drug effects; Toxicity Tests / methods; Tretinoin / pharmacology; United States; United States Environmental Protection Agency
TL;DR: Results demonstrate that an in vivo assay with a crustacean species customarily employed in toxicity testing can be used to effectively screen chemicals for juvenoid-modulating activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Membrane uptake kinetics of jet fuel aromatic hydrocarbons from aqueous solutions studied by a membrane-coated fiber technique

TOXICOLOGY MECHANISMS AND METHODS, 15(4), 307–316.

author keywords: uptake kinetics; membrane-coated fiber; partition coefficient; jet fuel; aromatic hydrocarbons
TL;DR: The results suggest that the MCF technique can detect subtle differences in molecular interactions of the two group derivatives between the two membrane/water systems and may be used to study the absorption and permeation properties of closely related compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Essential function for the kinase TAK1 in innate and adaptive immune responses

NATURE IMMUNOLOGY, 6(11), 1087–1095.

MeSH headings : Animals; B-Lymphocytes / drug effects; B-Lymphocytes / enzymology; B-Lymphocytes / immunology; CD40 Antigens / pharmacology; Embryo, Mammalian / cytology; Fibroblasts / drug effects; Fibroblasts / enzymology; Gene Deletion; Immunity, Innate; Interleukin-17 / pharmacology; Lymphopoiesis; MAP Kinase Kinase Kinases / deficiency; MAP Kinase Kinase Kinases / genetics; MAP Kinase Kinase Kinases / physiology; Membrane Glycoproteins / immunology; Mice; Mice, Mutant Strains; NF-kappa B / pharmacology; Receptors, Antigen, B-Cell / agonists; Receptors, Antigen, B-Cell / immunology; Receptors, Cell Surface / immunology; Toll-Like Receptors; Tumor Necrosis Factor-alpha / pharmacology
TL;DR: It is shown that TAK1 is key in the cellular response to a variety of stimuli and was indispensable for cellular responses to Toll-like receptor ligands, CD40 and B cell receptor crosslinking. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart

CIRCULATION RESEARCH, 97(9), 872–879.

author keywords: ischemia; AMP-activated protein kinase; p38 MAPK mitogen-activated protein kinase; transforming growth factor-beta-activated protein kinase 1-binding protein 1; glucose transport
MeSH headings : AMP-Activated Protein Kinases; Aminoimidazole Carboxamide / analogs & derivatives; Aminoimidazole Carboxamide / pharmacology; Animals; Anisomycin / pharmacology; Cell Hypoxia; Enzyme Activation; Glucose / metabolism; Glucose Transporter Type 4 / metabolism; Intracellular Signaling Peptides and Proteins / metabolism; MAP Kinase Kinase 3 / physiology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multienzyme Complexes / physiology; Myocardial Ischemia / enzymology; Protein Serine-Threonine Kinases / physiology; Protein Transport; Rats; Rats, Sprague-Dawley; Ribonucleotides / pharmacology; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: AMP-activated protein kinase has an important role in promoting p38 MAPK activation in the ischemic heart by inducing p38MAPK autophosphorylation through interaction with the scaffold protein TAB1. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Movement of proteins across the digestive system of the tobacco budworm, Heliothis virescens

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, 117(2), 135–146.

author keywords: meal pad; protein delivery; peptide; BSA; anti-BSA; midgut; hemolymph; Lepidoptera; Noctuidae
TL;DR: Bovine serum albumin (BSA) and anti‐BSA polyclonal antibody were used as model polypeptides to examine the movement of foreign proteins across the insect digestive system and their accumulation in hemolymph of fourth stadium tobacco budworms, Heliothis virescens (Fabricius) (Lepidoptera: Noctuidae). (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

A comparative study on androgen metabolism in three invertebrate species

General and Comparative Endocrinology, 143(3), 211–221.

By: G. Janer, G. LeBlanc & C. Porte

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2005 journal article

The mystery of Dos Bocas Reservoir, Puerto Rico: Explaining extreme spatial heterogeneity in largemouth bass distribution

Caribbean Journal of Science, 41(4), 804–814.

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress

ONCOGENE, 24(51), 7567–7578.

By: Y. Tsuji n

author keywords: ferritin; oxidative stress; JunD; AP1; ARE; iron
MeSH headings : Antioxidants / physiology; Carcinoma, Hepatocellular / pathology; Ferritins / biosynthesis; Ferritins / physiology; Humans; Iron / metabolism; Leukemia, Erythroblastic, Acute / pathology; Liver Neoplasms / pathology; Oxidative Stress; Protein Isoforms; Proto-Oncogene Proteins c-jun / physiology; Response Elements; Transcription Factor AP-1 / physiology; Transcription, Genetic; Tumor Cells, Cultured
TL;DR: Results suggest that JunD is another ARE regulatory protein for transcriptional activation of the human ferritin H gene and probably other antioxidant genes containing the conserved ARE sequences by which JunD may confer cytoprotection during oxidative stress. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Joint action of polycyclic aromatic hydrocarbons: Predictive modeling of sublethal toxicity

AQUATIC TOXICOLOGY, 75(3), 253–262.

By: A. Olmstead n & G. LeBlanc n

author keywords: hazard assessment; risk assessment; response addition; synergy; mixture toxicology
MeSH headings : Algorithms; Animals; Daphnia / drug effects; Daphnia / growth & development; Dose-Response Relationship, Drug; Models, Biological; Polycyclic Aromatic Hydrocarbons / toxicity; Toxicology / methods
TL;DR: Results indicate that PAHs elicit toxicity to daphnids by multiple mechanisms and demonstrate an appropriate modeling approach to assess the toxicity of these PAH mixtures. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

In vivo role of 20-hydroxyecdysone in the regulation of the vitellogenin mRNA and egg development in the American dog tick, Dermacentor variabilis (Say)

JOURNAL OF INSECT PHYSIOLOGY, 51(10), 1105–1116.

By: D. Thompson n, S. Khalil n, L. Jeffers n, U. Ananthapadmanaban n, D. Sonenshine*, R. Mitchell*, C. Osgood*, C. Apperson n, R. Roe n

author keywords: 20-hydroxyecdysone; juvenile hormone; vitellogenin; vitellin; tick
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Dermacentor / genetics; Dermacentor / growth & development; Dermacentor / metabolism; Dermacentor / physiology; Ecdysterone / physiology; Female; Gene Expression Regulation, Developmental / physiology; Hemolymph / physiology; Molecular Sequence Data; Ovary / physiology; Peptide Mapping; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sesquiterpenes / metabolism; Vitellogenins / biosynthesis; Vitellogenins / genetics
TL;DR: It is indicated that ecdysteroids and not JH can initiate expression of the Vg gene, Vg protein synthesis and release into hemolymph, and Vg uptake into developing oocytes under bioassay conditions mimicking normal feeding on the host. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Determination of the partition coefficients and absorption kinetic parameters of chemicals in a lipophilic membrane/water system by using a membrane-coated fiber technique

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 24(1), 15–23.

author keywords: absorption kinetics; membrane-coated fiber; diffusion coefficient; partition coefficient; boundary layer
MeSH headings : Absorption / drug effects; Absorption / physiology; Kinetics; Lipid Metabolism; Membranes, Artificial; Organic Chemicals / pharmacokinetics; Water / metabolism
TL;DR: The kinetic model adequately described the absorption kinetics of the MCF technique and suggested that the absorption rate of a very lipophilic compound could be controlled by the boundary layer even though the diffusivity of the compound in the membrane is lower than that in the solution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 article

Testosterone-fatty acid esterification: A unique target for the endocrine toxicity of tributyltin to gastropods

LeBlanc, G. A., Gooding, M. P., & Sternberg, R. M. (2005, February). INTEGRATIVE AND COMPARATIVE BIOLOGY, Vol. 45, pp. 81–87.

By: G. LeBlanc n, M. Gooding n & R. Sternberg n

TL;DR: Observations of imposex and free testosterone levels were elevated in field collected snails containing high tin levels, while testosterone-fatty acid ester pools were reduced in these organisms, indicating that tributyltin elevates free testosterone by reducing the retention of testosterone as fatty acid-esters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway

GENES TO CELLS, 10(5), 447–454.

MeSH headings : Adaptor Proteins, Signal Transducing / genetics; Adaptor Proteins, Signal Transducing / metabolism; Animals; I-kappa B Kinase; Interleukin-1 / metabolism; Mice; Mutation; NF-kappa B / metabolism; Protein Serine-Threonine Kinases / metabolism; Protein Structure, Tertiary; Signal Transduction / physiology; TNF Receptor-Associated Factor 6 / metabolism; Ubiquitin / metabolism
TL;DR: TAK1‐binding protein 2 (TAB2) functions to facilitate TRAF6 ubiquitination and thereby mediates IL‐1‐induced cellular events, and a conserved ubiquitin binding domain in TAB2, the CUE domain, is important for this function. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Predicting adsorption isotherms for aqueous organic micropollutants from activated carbon and pollutant properties

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 39(9), 3393–3400.

Contributors: L. Li n, P. Quinlivan n & D. Knappe n

MeSH headings : Adsorption; Carbon / chemistry; Carcinogens / chemistry; Forecasting; Methyl Ethers / chemistry; Models, Theoretical; Solvents / chemistry; Temperature; Trichloroethylene / chemistry; Water Pollutants, Chemical
TL;DR: A method based on the Polanyi-Dubinin-Manes (PDM) model is presented to predict adsorption isotherms of aqueous organic contaminants on activated carbons, with predictions that agreed well with experimental data for three adsorbents and two adsorbates that were not used to calibrate the model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 journal article

Diminished expression of C/EBP alpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBP alpha in carcinoma cells inhibits proliferation

Cancer Research, 65(3), 861–867.

By: M. Shim, K. Powers, S. Ewing, S. Zhu & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Detection and identification of histamine-producing bacteria associated with harvesting and processing mahimahi and yellowfin tuna

JOURNAL OF FOOD PROTECTION, 68(8), 1676–1682.

By: D. Allen n, D. Green n, G. Bolton n, L. Jaykus n & W. Cope n

MeSH headings : Animals; Consumer Product Safety; Food Contamination / analysis; Food Handling / methods; Food Microbiology; Food-Processing Industry / methods; Food-Processing Industry / standards; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacteria / metabolism; Histamine / analysis; Histamine / biosynthesis; Humans; North Carolina; Perciformes / microbiology; Seafood / microbiology; Tuna / microbiology
TL;DR: It is revealed that gram-negative bacteria might not be solely responsible for histamine production in at-risk fish, and no seafood safety risks were found under the standard industry practices observed in this study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 article

Androgen metabolism in invertebrates and its modulation by xenoandrogens - A comparative study

TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY, Vol. 1040, pp. 354–356.

By: G. Janer*, G. LeBlanc n & C. Porte*

author keywords: androgen; steroid metabolism; organotin; fenarimol; invertebrates
MeSH headings : Androgens / metabolism; Animals; Crustacea / metabolism; Echinodermata / metabolism; Mollusca / metabolism; Species Specificity; Xenobiotics / metabolism
TL;DR: The work evidenced different sensitivity of those pathways to androgenic compounds, together with interphyla differences in androgen metabolism, as well as different sensitivity and tissue‐specific distribution of those enzymatic activities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean

JOURNAL OF EXPERIMENTAL BIOLOGY, 208(1), 15–23.

author keywords: Cladocera; juvenoid; endocrine disruption; evolution; nuclear receptor; Daphnia magna
MeSH headings : Analysis of Variance; Animals; Base Sequence; DNA Primers; Daphnia / physiology; Electrophoresis; Fatty Acids, Unsaturated / pharmacology; Hemoglobins / genetics; Hemoglobins / metabolism; Male; Molecular Sequence Data; Reproduction / physiology; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sex Differentiation / drug effects; Signal Transduction / physiology; Spectrophotometry; Stress, Physiological / metabolism; Terpenes / metabolism
TL;DR: It is demonstrated that two responses to environmental stress signaling in the crustacean Daphnia magna - hemoglobin accumulation and male offspring production - are co-elevated by the crustACEan terpenoid hormone methyl farnesoate and several synthetic analogs, suggesting that both processes are regulated by the same ter penoid signaling pathway. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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