Works Published in 2020
Displaying works 61 - 80 of 114 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair
Antioxidants.
author keywords: lycopene; beta-carotene; lung cancer; base excision repair; gap junction communication; all-trans retinoic acid; oxidative stress
TL;DR:
Lycopene treatment at a lower dosage could inhibit smoke-induced oxidative stress and promote genome stability and shed light on the molecular mechanism of lycopene action against lung cancer.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: July 26, 2020
2020 journal article
Identification of mixed linkage beta-glucan quantitative trait loci and evaluation of AsCslF6 homoeologs in hexaploid oat
CROP SCIENCE, 60(2), 914–933.
Sources: Web Of Science, NC State University Libraries
Added: July 13, 2020
2020 journal article
Nanoparticulate Gels for Cutaneous Administration of Caffeic Acid
NANOMATERIALS, 10(5).
author keywords: solid lipid nanoparticles; caffeic acid; poloxamer; small angle X-ray scattering; cigarette smoke
TL;DR:
The antioxidant effect of caffeic acid loaded in nanoparticulate gel has been demonstrated by ex-vivo evaluation on human skin explants exposed to cigarette smoke, suggesting a protective role exerted by the nanoparticles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 13, 2020
2020 journal article
Particulate Matter Induces Tissue OxInflammation: From Mechanism to Damage
ANTIOXIDANTS & REDOX SIGNALING, 33(4), 308–326.
author keywords: oxidative stress; inflammation; particulate matter; air pollution
MeSH headings : Air Pollution / adverse effects; Animals; Cytokines / metabolism; Disease Susceptibility; Humans; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Inflammation Mediators / metabolism; Oxidation-Reduction; Oxidative Stress; Particulate Matter / adverse effects; Reactive Oxygen Species / metabolism
TL;DR:
Research is required to elucidate the exact mechanisms by which PM exposure results in adverse health effects, in terms of the relationship between the redox responses triggered by the presence of the particles and the inflammation observed in the different organs, so the development/exacerbation of PM-associated health problems can be prevented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 13, 2020
2020 journal article
Redox regulation of cutaneous inflammasome by ozone exposure
FREE RADICAL BIOLOGY AND MEDICINE, 152, 561–570.
MeSH headings : Caspase 1 / metabolism; Humans; Hydrogen Peroxide; Inflammasomes / metabolism; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Oxidation-Reduction; Ozone / toxicity; Reactive Oxygen Species
TL;DR:
It is demonstrated that O3 can activate cutaneous inflammasome in a redox dependent manner suggesting a possible role of this new pathway in pollution induced inflammatory skin conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 13, 2020
2020 review
The Enigma of Bioactivity and Toxicity of Botanical Oils for Skin Care
[Review of ]. FRONTIERS IN PHARMACOLOGY, 11.
author keywords: natural oils; skin barrier function; skin aging; wound healing; atopic dermatitis; for skin care
TL;DR:
This review contrasted the functionality of skin oils versus the differential biological and toxicological effects of major plant oils, and to correlate them to their compositional changes to promote awareness of health practitioners and botanical product manufacturers for the safety and efficacy of oil-based interventions based on their fatty acid profiles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 13, 2020
2020 journal article
In Vitro Evaluation of a Novel Synthetic Bilirubin Analog as an Antioxidant and Cytoprotective Agent for Pancreatic Islet Transplantation
Cell Transplantation, 29.
Contributors: E. Luckring n, P. Parker n, H. Hani*, M. Grace n , M. Lila n, J. Pierce n, C. Adin *
MeSH headings : Animals; Antioxidants / chemical synthesis; Antioxidants / chemistry; Bilirubin / analogs & derivatives; Bilirubin / chemical synthesis; Bilirubin / chemistry; Cell Survival / physiology; Fluorescence Recovery After Photobleaching; Islets of Langerhans Transplantation / methods; Molecular Structure; Swine
TL;DR:
Two bilirubin analogs are synthesized that can be produced without the use of animal-derived products and have promising antioxidant and cytoprotective effects, limiting islet cell death in a model of islet transplantation hypoxic stress.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: July 9, 2020
2020 journal article
Proteomic pro fi ling reveals mitochondrial alterations in Rett syndrome
FREE RADICAL BIOLOGY AND MEDICINE, 155, 37–48.
MeSH headings : Gene Expression Profiling; Humans; Methyl-CpG-Binding Protein 2 / genetics; Mutation; Proteome / genetics; Proteomics; Rett Syndrome / genetics
TL;DR:
The proteomic analysis confirms the pathological relevance of mitochondrial dysfunction in RTT pathogenesis and progression and carries out the first comprehensive characterization of RTT cellular proteome, showing mainly changes in expression of proteins involved in the mitochondrial network.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 6, 2020
2020 journal article
Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes
INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(2), 112–119.
author keywords: inflammation exercise; oxidative stress; peripheral blood mononuclear cells
TL;DR:
Flavonoid supplementation prior to intensive exercise decreased plasma peroxidation and oxidative damage, as determined by 4-hydroxynonenal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 6, 2020
2020 journal article
Fatigue-Creep Interaction of P92 Steel and Modified Constitutive Modelling for Simulation of the Responses
METALS, 10(3).
author keywords: P92 steel; fatigue-creep interaction; unified constitutive model; static recovery; stress relaxation
Source: Web Of Science
Added: July 6, 2020
2020 review
Terms and nomenclature used for plant-derived components in nutrition and related research: efforts toward harmonization
[Review of ]. NUTRITION REVIEWS, 78(6), 451–458.
author keywords: bioactive; carotenoid; flavonoid; nomenclature; nutraceutical; phytochemical; phytonutrient; polyphenol
MeSH headings : Biomedical Research; Humans; Nutritional Sciences; Phytochemicals; Plant Preparations; Terminology as Topic
TL;DR:
The aim in this article is to establish scientific criteria for definitions that could be applied to clearly define and differentiate commonly used terms and thus ensure their consistent application in the scientific literature.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 29, 2020
2020 journal article
Enhanced stability of berry pomace polyphenols delivered in protein-polyphenol aggregate particles to an in vitro gastrointestinal digestion model
Food Chemistry, 331, 127279.
Contributors: J. Xiong n , Y. Chan n, T. Rathinasabapathy n , M. Grace n , S. Komarnytsky n & M. Lila n
author keywords: Food matrix; By-product; Stability; Antioxidant; Anti-inflammatory
MeSH headings : Animals; Anthocyanins / analysis; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Antioxidants / analysis; Blueberry Plants / chemistry; Digestion; Food-Processing Industry; Fruit / chemistry; Mice; Plant Extracts / chemistry; Plant Extracts / pharmacokinetics; Plant Proteins, Dietary / chemistry; Polyphenols / pharmacokinetics; Proanthocyanidins / analysis; RAW 264.7 Cells; Vitis / chemistry
TL;DR:
Protein-polyphenol particle digests retained 1.5 to 2-fold higher antioxidant capacity and suppressed the expression of pro-inflammatory cytokines, iNOS, IL6, and IL1β, compared to unmodified extract digests, which only suppressed IL6.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: June 19, 2020
2020 article
Protective effects of a comprehensive topical antioxidant against ozone-induced damage in a reconstructed human skin model
ARCHIVES OF DERMATOLOGICAL RESEARCH.
author keywords: Antioxidants; Ozone; Oxidative damage; Cosmeceuticals; Free radicals; Reactive Oxygen Species (ROS)
MeSH headings : Administration, Cutaneous; Antioxidants / administration & dosage; Cell Culture Techniques; Cells, Cultured; Drug Evaluation, Preclinical; Epidermis / drug effects; Epidermis / pathology; Humans; Lipid Peroxidation / drug effects; Oxidative Stress / drug effects; Ozone / adverse effects; Reactive Oxygen Species / metabolism; Skin Aging / drug effects
TL;DR:
A comprehensive topical antioxidant significantly diminished O 3 -induced oxidative damage in a human epidermal skin model and inhibited damage in tissues exposed to O 3 with no significant changes in epidermis structure.
(via Semantic Scholar)
Source: NC State University Libraries
Added: June 16, 2020
2020 journal article
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1866(7).
author keywords: Rett syndrome; Skin primary fibroblasts; Proteasome; alpha-Ring; PAC1; PAC2
MeSH headings : Codon, Nonsense / genetics; Dual Specificity Phosphatase 2 / genetics; Fibroblasts / metabolism; Gene Expression Regulation; Genetic Diseases, X-Linked / genetics; Genetic Diseases, X-Linked / pathology; Humans; Methyl-CpG-Binding Protein 2 / genetics; Neurodevelopmental Disorders / genetics; Neurodevelopmental Disorders / pathology; Primary Cell Culture; Proteasome Endopeptidase Complex / genetics; Proteolysis; Rett Syndrome / genetics; Rett Syndrome / pathology; Skin / metabolism; Skin / pathology; Ubiquitin / genetics
TL;DR:
Molecular, transcription and proteomic analyses indicate that MeCP2 mutations down-regulate the expression of one proteasome subunit, α7, and of two chaperones, PAC1 and PAC2, which bind each other in the earliest step of proteAsome biogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 15, 2020
2020 journal article
Increasing Doses of Blueberry Polyphenols Alters Colonic Metabolism and Calcium Absorption in Ovariectomized Rats
MOLECULAR NUTRITION & FOOD RESEARCH, 64(12).
author keywords: blueberries; calcium absorption; colonic metabolism; pharmacokinetics; polyphenols
MeSH headings : Animals; Blueberry Plants / chemistry; Calcium / pharmacokinetics; Colon / drug effects; Colon / metabolism; Dietary Supplements; Dose-Response Relationship, Drug; Female; Flavonoids / urine; Hippurates / urine; Intestinal Absorption / drug effects; Ovariectomy; Phenols / metabolism; Phenols / urine; Polyphenols / administration & dosage; Polyphenols / analysis; Polyphenols / pharmacology; Rats, Sprague-Dawley
TL;DR:
It is indicated that increased doses of blueberry polyphenols induce changes in intestinal phenolic metabolism and increase calcium absorption, and Calcium absorption was significantly increased in the highest dose group.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 8, 2020
2020 journal article
Phenolic content, anti-inflammatory properties, and dermal wound repair properties of industrially processed and non-processed acai from the Brazilian Amazon
Food & Function, 11(6), 4903–4914.
Contributors: J. Xiong n , F. Matta*, M. Grace n , M. Lila n , N. Ward *, M. Felipe-Sotelo *, D. Esposito n
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Arecaceae; Brazil; Food Industry; Fruit; Humans; Mice; Phytotherapy; Plant Extracts / chemistry; Plant Extracts / pharmacology; Polyphenols / chemistry; RAW 264.7 Cells / drug effects; Wound Healing / drug effects
TL;DR:
The anti-inflammatory effect was diminished but wound healing effect was retained after pulp processing, suggesting the processing technology needs to be improved to maintain biological properties of acai fruit.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: June 5, 2020
2020 journal article
Formulation of protein–polyphenol particles for applications in food systems
Food & Function.
MeSH headings : Blueberry Plants / chemistry; Chemical Phenomena; Fruit / chemistry; Fruit and Vegetable Juices; Functional Food; Oryza; Particle Size; Plant Proteins, Dietary / chemistry; Polyphenols / chemistry; Vaccinium macrocarpon / chemistry; Whey Proteins / chemistry
TL;DR:
Particles formed with whey protein and blueberry juice significantly improved foam stability and drainage half-life and protein-polyphenol particles can be designed as ingredients to stabilize food structures and to increase delivery of health protective polyphenols and proteins in the diet.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 30, 2020
2020 journal article
Daily watermelon consumption decreases plasma sVCAM-1 levels in overweight and obese postmenopausal women
NUTRITION RESEARCH, 76, 9–19.
author keywords: Cardiovascular risk; Insulin; HOMA-IR; L-Citrulline; L-Arginine; Randomized, parallel assignment design
MeSH headings : Arginine / blood; Arginine / therapeutic use; Atherosclerosis / blood; Atherosclerosis / diet therapy; Atherosclerosis / prevention & control; Biomarkers / blood; Blood Glucose / metabolism; Body Composition; Citrulline / therapeutic use; Citrullus / chemistry; Diet; Female; Fruit / chemistry; Humans; Insulin / blood; Insulin Resistance; Lycopene / blood; Lycopene / therapeutic use; Middle Aged; Obesity / blood; Overweight / blood; Plant Extracts / blood; Plant Extracts / therapeutic use; Postmenopause; Vascular Cell Adhesion Molecule-1 / blood
TL;DR:
It is concluded that 6 weeks of watermelon supplementation improved soluble vascular cell adhesion molecule-1 levels, a marker connected to atherogenesis, independent of changes in body composition or glycemic control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 26, 2020
2020 journal article
Circadian Clock and OxInflammation: Functional Crosstalk in Cutaneous Homeostasis
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2020.
MeSH headings : Cells, Cultured; Circadian Clocks / physiology; Homeostasis; Humans; Inflammation / metabolism; Inflammation / pathology; Keratinocytes / cytology; Keratinocytes / metabolism; Skin / metabolism; Skin / pathology
TL;DR:
The results suggest that a synchronized circadian clock not only facilitates the protective role of NRF2 in terms of a faster and more efficient defensive response against environmental insults but also moderates the cellular damage resulting from a condition of chronic inflammation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 26, 2020
2020 journal article
Postprandial skeletal muscle metabolism following a high-fat diet in sedentary and endurance-trained males
JOURNAL OF APPLIED PHYSIOLOGY, 128(4), 872–883.
author keywords: exercise; high-fat diet; metabolic flexibility; skeletal muscle; substrate oxidation
MeSH headings : Diet, High-Fat; Endurance Training; Fasting; Humans; Male; Muscle, Skeletal; Postprandial Period
TL;DR:
Insight is provided into differing substrate metabolism responses between SED and ET individuals and the role the prevailing diet may play in modulating fasting and postprandial metabolic responses in skeletal muscle is highlighted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 18, 2020
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