Works Published in 2016
Displaying works 81 - 100 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Widespread somatosensory sensitivity in naturally occurring canine model of osteoarthritis
PAIN, 157(6), 1325–1332.
author keywords: Animal model; Osteoarthritis; Spontaneous osteoarthritis model; Quantitative sensory testing
MeSH headings : Animals; Arthralgia / physiopathology; Arthralgia / veterinary; Central Nervous System Sensitization / physiology; Dogs; Osteoarthritis / physiopathology; Osteoarthritis / veterinary; Pain Measurement; Pain Threshold / physiology; Physical Stimulation; Sensory Thresholds / physiology
TL;DR:
The canine spontaneous OA model is associated with somatosensory sensitivity, likely indicative of central sensitization in human patients' chronic pain, and is validated as an appropriate model of the human OA pain condition.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Use of oral trazodone for sedation in cats: a pilot study
JOURNAL OF FELINE MEDICINE AND SURGERY, 18(6), 476–482.
MeSH headings : Accelerometry / veterinary; Administration, Oral; Animals; Anti-Anxiety Agents / administration & dosage; Behavior, Animal / drug effects; Cats / physiology; Male; Pilot Projects; Trazodone / administration & dosage; Treatment Outcome
TL;DR:
Trazodone was well tolerated in this population of cats and caused appreciable sedation at all doses and further studies are recommended to investigate the use of oral trazodone in cats for the purpose of decreasing anxiety assocaited with transportation and examination.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Uncovering diversity in the development of central noradrenergic neurons and their efferents
BRAIN RESEARCH, 1641, 234–244.
author keywords: Norepinephrine; Hoxb1; Fate map; Recombinase-based intersectional; genetic fate mapping; Efferents; Rhombomere
MeSH headings : Adrenergic Neurons / cytology; Adrenergic Neurons / physiology; Animals; Brain / cytology; Brain / growth & development; Brain / physiology; Neural Pathways / cytology; Neural Pathways / growth & development; Neural Pathways / physiology
TL;DR:
It is demonstrated that Hoxb1 expression is required by a subset of neurons in the pons with more restricted axonal targets than the full Hox b1-derived subpopulation, and the unique projection profile of this newly defined subpopulation suggests that it may be functionally distinct.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
The effect of high dose oral manganese exposure on copper, iron and zinc levels in rats
BIOMETALS, 29(3), 417–422.
author keywords: Manganese; Copper; Iron; Zinc; Exposure
MeSH headings : Administration, Oral; Animals; Copper / metabolism; Diet; Homeostasis / drug effects; Iron / metabolism; Male; Manganese / administration & dosage; Manganese / analysis; Manganese / toxicity; Rats; Rats, Inbred F344; Zinc / metabolism
TL;DR:
While manganese exposure affected levels of all metals, particularly in the frontal cortex and liver, copper levels were most prominently affected and suggests an under-appreciated effect of manganae exposure on copper homeostasis which may contribute to the understanding of the pathophysiology of mangansese toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus
Journal of Cell Science, 129(9), 1855–1865.
author keywords: TAK1; Endoplasmic reticulum stress; Leptin; Hypothalamus; Obesity
MeSH headings : Animals; Dietary Fats / adverse effects; Dietary Fats / pharmacology; Endoplasmic Reticulum Stress; Hyperphagia / chemically induced; Hyperphagia / genetics; Hyperphagia / metabolism; Hyperphagia / pathology; Hypothalamus / metabolism; Hypothalamus / pathology; Leptin / genetics; Leptin / metabolism; MAP Kinase Kinase Kinases / genetics; MAP Kinase Kinase Kinases / metabolism; Mice; Mice, Knockout; Obesity / chemically induced; Obesity / genetics; Obesity / metabolism; Obesity / pathology; Sterol Regulatory Element Binding Proteins / genetics; Sterol Regulatory Element Binding Proteins / metabolism
TL;DR:
It is found that deletion of Tak1 increased ER volume and facilitated ER-stress tolerance in cultured cells, which was mediated by upregulation of sterol-regulatory-element-binding protein (SREBP)-dependent lipogenesis and central nervous system (CNS) deletion upregulated SREBP-target lipogenic genes and blocked ER stress in the hypothalamus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 journal article
Survey of practices and perceptions regarding feline onychectomy among private practitioners
Journal of the American Veterinary Medical Association, 249(3), 291–298.
MeSH headings : Animals; Behavior, Animal; Cat Diseases / surgery; Cats; Colorado / epidemiology; Hoof and Claw / surgery; Practice Patterns, Physicians'; Private Practice; Surgical Procedures, Operative / statistics & numerical data; Surgical Procedures, Operative / veterinary; Surveys and Questionnaires; Veterinary Medicine
TL;DR:
In this sample, most veterinarians performing the procedure reported that they did so infrequently, and most offered nonsurgical alternatives to the procedure, which is a controversial topic.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
FEASIBILITY AND SAFETY OF CONTRAST-ENHANCED ULTRASOUND IN THE DISTAL LIMB OF SIX HORSES
VETERINARY RADIOLOGY & ULTRASOUND, 57(3), 282–289.
author keywords: contrast-enhanced; equine intra-arterial; ultrasound
MeSH headings : Animals; Contrast Media / administration & dosage; Contrast Media / adverse effects; Female; Hindlimb / diagnostic imaging; Horses; Injections, Intra-Arterial / veterinary; Injections, Intravenous / veterinary; Male; Muscle, Skeletal / diagnostic imaging; Pilot Projects; Prospective Studies; Ultrasonography / adverse effects; Ultrasonography / veterinary
TL;DR:
Findings from this study indicated that CEUS is a feasible and safe diagnostic test for evaluation of the equine distal limb and future studies are needed to assess the clinical utility of this test for horses with musculoskeletal diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Effects of Matrix Metalloproteinases on the Performance of Platelet Fibrin Gel Spiked With Cardiac Stem Cells in Heart Repair
STEM CELLS TRANSLATIONAL MEDICINE, 5(6), 793–803.
author keywords: Cardiac stem cells; Platelet fibrin gel; Matrix metalloproteinases; Heart repair
MeSH headings : Animals; Blood Platelets / metabolism; Dipeptides / administration & dosage; Disease Models, Animal; Echocardiography; Fibrin / administration & dosage; Humans; Matrix Metalloproteinase Inhibitors / administration & dosage; Matrix Metalloproteinases / metabolism; Myocardial Infarction / enzymology; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / metabolism; Rats; Regeneration / drug effects; Stem Cell Transplantation
TL;DR:
It is suggested that MMPs play a critical role in the therapeutic benefits of platelet fibrin gel spiked with cardiac stem cells for treating MI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Effect of disrupted mitochondria as a source of damage-associated molecular patterns on the production of tumor necrosis factor alpha by splenocytes from dogs
American Journal of Veterinary Research, 77(6), 604–612.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Diphenhydramine exposure in dogs: 621 cases (2008-2013)
Journal of the American Veterinary Medical Association, 249(1), 77–82.
MeSH headings : Animals; Anti-Allergic Agents / poisoning; Diphenhydramine / poisoning; Dog Diseases / epidemiology; Dog Diseases / pathology; Dog Diseases / prevention & control; Dogs; Female; Illinois / epidemiology; Male; Poison Control Centers / statistics & numerical data; Poisoning / epidemiology; Poisoning / veterinary; Retrospective Studies; Severity of Illness Index
TL;DR:
Results indicated that dogs exposed to diphenhydramine developed clinical signs of toxicosis fairly infrequently, and those clinical signs were generally mild and primarily affected the neurologic and cardiovascular systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Cyniclomyces guttulatus Infection in Dogs: 19 Cases (2006-2013)
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 52(1), 42–51.
TL;DR:
It is suggested that additional studies to determine if C. guttulatus is a potential cause or consequence of gastrointestinal illness in dogs may be warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
What is your diagnosis? Computed tomography in the diagnosis of left abomasal displacement and ulceration with abomasal-subcutaneous fistula in a calf
Journal of the American Veterinary Medical Association, 248(10), 1117–1119.
Contributors: L. Hsuan, W. Tulley & E. Cohen*
MeSH headings : Abdominal Cavity / pathology; Abomasum / pathology; Animals; Bezoars / diagnosis; Bezoars / pathology; Bezoars / surgery; Bezoars / veterinary; Cattle; Cattle Diseases / diagnosis; Cattle Diseases / pathology; Cattle Diseases / surgery; Fatal Outcome; Female; Gastric Fistula / diagnosis; Gastric Fistula / pathology; Gastric Fistula / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Ventricular arrhythmias in Rhodesian Ridgebacks with a family history of sudden death and results of a pedigree analysis for potential inheritance patterns
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 248(10), 1135–1138.
MeSH headings : Animals; Arrhythmias, Cardiac / pathology; Arrhythmias, Cardiac / veterinary; Death, Sudden / veterinary; Dog Diseases; Dogs; Female; Genetic Predisposition to Disease; Male; Pedigree
TL;DR:
Holter monitoring of Rhodesian Ridgebacks with a family history of an arrhythmia or sudden death is recommended for early diagnosis of disease and an autosomal recessive pattern of inheritance in the studied dogs was likely, and inbreeding should be strongly discouraged.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 article
The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures
COUNTERMEASURES AGAINST CHEMICAL THREATS, Vol. 1374, pp. 111–122.
Contributors: D. Feinstein *, B. Akpa n , M. Ayee*, A. Boullerne*, D. Braun *, S. Brodsky *, D. Gidalevitz *, Z. Hauck*
author keywords: superwarfarins; brodifacoum; HPLC; lipid membrane; neuropathology; nephrotoxicity; intralipid
MeSH headings : Animals; Anticoagulants / adverse effects; Anticoagulants / analysis; Anticoagulants / chemistry; Biomarkers / analysis; Environmental Exposure / analysis; Humans; Kidney / drug effects; Kidney / pathology; Nervous System / drug effects; Nervous System / pathology; Warfarin / adverse effects; Warfarin / analysis; Warfarin / chemistry; Warfarin / poisoning
TL;DR:
This review summarizes superwarfarin development, biology and pathophysiology, their threat as weapons, and possible therapeutic approaches, including both vitamin K–dependent and –independent effects, which are not mitigated by vitamin K therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2016 journal article
Pharmacokinetics of minocycline in domestic cats
JOURNAL OF FELINE MEDICINE AND SURGERY, 18(4), 257–263.
MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Biological Availability; Cat Diseases / drug therapy; Cats; Chromatography, High Pressure Liquid / veterinary; Half-Life; Infusions, Intravenous; Microbial Sensitivity Tests; Minocycline / administration & dosage; Minocycline / pharmacokinetics
TL;DR:
The pharmacokinetics of minocycline in domestic cats was determined in order to facilitate dosage decisions and it was found that one 50 mg capsule orally q24h would provide appropriate dosing for most cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 personal communication
How to (properly) determine the beyond-use date and stability of a compounded formulation for pets
Papich, M. G., Brown, S., & Kirk, L. (2016, April).
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Evaluation of associations among Coxiella burnetii and reproductive abnormalities in cats
JOURNAL OF FELINE MEDICINE AND SURGERY, 18(4), 344–347.
MeSH headings : Animals; Cat Diseases / microbiology; Cats; Coxiella burnetii / isolation & purification; Female; Infertility, Female / microbiology; Infertility, Female / veterinary; Polymerase Chain Reaction / veterinary; Prevalence; Q Fever / microbiology; Q Fever / veterinary
TL;DR:
While C burnetii could not be confirmed by sequence analysis or immunohistochemistry, the PCR positive prevalence rate was similar to that published previously and biosafety precautions should be taken when working with cats that are aborting or parturient.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes
PLOS ONE, 11(8).
MeSH headings : Amino Acid Sequence / genetics; Animals; Anti-Bacterial Agents / immunology; Antimicrobial Cationic Peptides / genetics; Antimicrobial Cationic Peptides / immunology; Disease Resistance / genetics; Disease Resistance / immunology; Fish Proteins / genetics; Fish Proteins / immunology; Fishes / immunology; Fishes / microbiology; Fishes / parasitology; Gene Expression; Immunity, Innate; Sequence Alignment
TL;DR:
Four new piscidin isoforms in the hybrid striped bass are identified and their tissue distributions are described, which may help in the future development of disease-resistant lines of striped bass and white bass that could be used to produce superior hybrids for aquaculture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes
Immunogenetics, 68(4), 295–312.
author keywords: Innate immunity; Immunoglobulin domain; Haplotype; Polymorphism; Immune receptor
MeSH headings : Animals; Gene Expression Regulation, Developmental; Genes, MHC Class I / genetics; Genes, MHC Class I / immunology; Genetic Linkage; Haplotypes; Immunity, Innate; Immunoglobulins / genetics; Lipids / genetics; Receptors, Immunologic / genetics; Receptors, Immunologic / immunology; Zebrafish / genetics; Zebrafish / growth & development; Zebrafish / immunology; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Pharmacokinetics of detomidine following intravenous or oral-transmucosal administration and sedative effects of the oral-transmucosal treatment in dogs
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(4), 413–420.
MeSH headings : Administration, Mucosal; Administration, Oral; Animals; Biological Availability; Chromatography, Liquid; Dexmedetomidine / administration & dosage; Dexmedetomidine / blood; Dexmedetomidine / pharmacokinetics; Dogs / metabolism; Female; Gels; Half-Life; Hypnotics and Sedatives / administration & dosage; Hypnotics and Sedatives / blood; Hypnotics and Sedatives / pharmacokinetics; Imidazoles / administration & dosage; Imidazoles / blood; Imidazoles / pharmacokinetics; Infusions, Intravenous / veterinary; Male; Mass Spectrometry
TL;DR:
Detomidine gel administered by the OTM route provided sedation suitable for a short, minimally invasive procedure in healthy dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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