Works Published in 2021

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Displaying works 61 - 80 of 210 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 article

Assessing the infiltration of immune cells in the upper trachea mucosa after infectious laryngotracheitis virus (ILTV) vaccination and challenge

Maekawa, D., Whang, P., Riblet, S. M., Hurley, D. J., Guy, J. S., & Garcia, M. (2021, November 2). AVIAN PATHOLOGY, Vol. 11.

By: D. Maekawa*, P. Whang*, S. Riblet*, D. Hurley*, J. Guy n & M. Garcia*

author keywords: Infectious laryngotracheitis virus (ILTV); chicken embryo origin (CEO); tissue culture origin (TCO); herpesvirus of turkey-laryngotracheitis (HVT-LT); protection; infiltration
MeSH headings : Animals; Chick Embryo; Chickens / immunology; Herpesvirus 1, Gallid / immunology; Herpesvirus 1, Meleagrid; Mucous Membrane; Trachea; Vaccination / veterinary; Vaccines
TL;DR: The very robust protection provided by CEO vaccination was characterized by minimal immune cell infiltration to the trachea mucosa, in contrast to partial protection induced by the TCO and rHVT-LT vaccines, which requires a prolonged period of T cell expansion to overcome the established infection in the trachoma mucosa. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 23, 2021

2021 article

Interpretable machine learning applied to on-farm biosecurity and porcine reproductive and respiratory syndrome virus

Sykes, A. L., Silva, G. S., Holtkamp, D. J., Mauch, B. W., Osemeke, O., Linhares, D. C. L., & Machado, G. (2021, November 16). TRANSBOUNDARY AND EMERGING DISEASES, Vol. 10.

By: A. Sykes n, G. Silva*, D. Holtkamp*, B. Mauch*, O. Osemeke*, D. Linhares*, G. Machado n

Contributors: A. Sykes n, G. Silva*, D. Holtkamp*, B. Mauch*, O. Osemeke*, D. Linhares*, G. Machado n

author keywords: disease of swine; interpretable machine learning; on-farm biosecurity; PRRSV
MeSH headings : Animal Husbandry / methods; Animals; Biosecurity; Disease Susceptibility / veterinary; Farms; Humans; Machine Learning; Porcine Reproductive and Respiratory Syndrome / epidemiology; Porcine Reproductive and Respiratory Syndrome / prevention & control; Porcine respiratory and reproductive syndrome virus; Swine
TL;DR: A novel interpretable machine learning toolkit was developed to benchmark farms and production systems by predicted risk, and quantify the impact of biosecurity practices on disease risk at individual farms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 23, 2021

2021 journal article

Identification of CTX-M type ESBL E. coli from sheep and their abattoir environment using whole-genome sequencing

Pathogens, 10(11), 1480.

By: N. Atlaw n, S. Keelara n, M. Correa n, D. Foster n, W. Gebreyes*, A. Aidara-Kane*, L. Harden n, S. Thakur n, P. Fedorka-Cray n

author keywords: abattoir environment; antimicrobial resistance; E. coli; ESBL; North Carolina; sheep; whole-genome sequencing
TL;DR: This is the first comprehensive AMR and WGS report on ESBL E. coli from sheep and abattoir environments in the United States and associated AMR genes, point mutations, and plasmids. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 16, 2021

2021 journal article

What is your diagnosis? Dermal mass in a dog

Veterinary Clinical Pathology, 51(1), 161–163.

author keywords: ALP cytochemical stain; Canine; Cutaneous; Metastasis; Osteosarcoma
MeSH headings : Animals; Bone Neoplasms / veterinary; Dog Diseases / diagnosis; Dogs; Osteosarcoma / diagnosis; Osteosarcoma / veterinary
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: November 15, 2021

2021 article

Identifying patient-level risk factors associated with non-β-lactam resistance outcomes in invasive methicillin-resistant Staphylococcus aureus infections in the United States using chain graphs

Love, W. J., Wang, C. A., & Lanzas, C. (2021, November 14). (Vol. 11). Vol. 11.

By: W. Love n, C. Wang n & C. Lanzas n

TL;DR: This study analyzed MRSA surveillance data collected by the Centers for Disease Control and Prevention using chain graphs to identify risk factors for individual phenotypic resistance outcomes (reported as minimum inhibitory concentration, MIC) while considering the correlations among themselves. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: November 15, 2021

2021 article

Modelling the role of mortality-based response triggers on the effectiveness of African swine fever control strategies

Machado, G., Farthing, T. S., Andraud, M., Nunes Lopes, F. P., & Lanzas, C. (2021, October 15). TRANSBOUNDARY AND EMERGING DISEASES, Vol. 10.

By: G. Machado n, T. Farthing n, M. Andraud*, F. Nunes Lopes* & C. Lanzas n

Contributors: G. Machado n, T. Farthing n, M. Andraud*, F. Lopes* & C. Lanzas n

author keywords: network modelling; secure business continuity; surveillance; swine disease dynamics
MeSH headings : African Swine Fever / epidemiology; African Swine Fever / prevention & control; African Swine Fever Virus / physiology; Animals; Disease Outbreaks / veterinary; Epidemics / prevention & control; Epidemics / veterinary; Farms; Swine; Swine Diseases / epidemiology
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 8, 2021

2021 journal article

Using rheology to quantify the effects of localized collagenase treatments on uterine fibroid digestion

ACTA BIOMATERIALIA, 134, 443–452.

By: R. Corder n, S. Gadi n, R. Vachieri*, F. Jayes*, J. Cullen n, S. Khan n, D. Taylor*

author keywords: Uterine fibroids; Collagenase; Drug delivery; Rheology; Histology
MeSH headings : Animals; Collagenases; Digestion; Female; Humans; Leiomyoma / drug therapy; Mice; Rheology; Treatment Outcome; Uterine Neoplasms
TL;DR: Rheological results from an in vivo digestion study in mice show a significant reduction in tissue modulus and increase in tissue viscoelasticity 7 days after a single injection of LQG+CCH, and show promise for development of injectable and localized enzymatic therapies for uterine fibroids and other dense tumors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 8, 2021

2021 journal article

Key Characteristics of Cardiovascular Toxicants

ENVIRONMENTAL HEALTH PERSPECTIVES, 129(9).

By: L. Lind, J. Araujo*, A. Barchowsky*, S. Belcher n, B. Berridge*, N. Chiamvimonvat*, W. Chiu*, V. Cogliano* ...

MeSH headings : Air Pollutants / analysis; Air Pollution / analysis; Carcinogens; Environmental Pollutants / toxicity; Hazardous Substances / toxicity; Particulate Matter / analysis
TL;DR: The KCs could be used to identify potential CV toxicants and to define a set of test methods to evaluate CV toxicity in a more comprehensive and standardized manner than current approaches. (via Semantic Scholar)
Source: Web Of Science
Added: November 8, 2021

2021 review

Secretory Sorcery: Paneth Cell Control of Intestinal Repair and Homeostasis

[Review of ]. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 12(4), 1239–1250.

author keywords: Paneth cells; damage; intestine; ER stress; reversion
MeSH headings : Animals; Cell Differentiation; Cellular Microenvironment; Crohn Disease / etiology; Crohn Disease / metabolism; Crohn Disease / pathology; Disease Susceptibility; Homeostasis; Host Microbial Interactions; Humans; Intestinal Mucosa / microbiology; Intestinal Mucosa / physiology; Microbiota; Paneth Cells / physiology; Regeneration; Signal Transduction; Stem Cells / cytology; Stem Cells / metabolism; Wound Healing
TL;DR: The numerous ways Paneth cells can influence intestinal stem cells and their niche are discussed and the ways in which these cells can alter cells and other organ systems are highlighted. (via Semantic Scholar)
Source: Web Of Science
Added: November 8, 2021

2021 journal article

A cross-sectional study of the nasal and fecal microbiota of sows from different health status within six commercial swine farms

PEERJ, 9.

author keywords: Swine; Swine microbiota; Nasal and fecal microbiota; Cull sows; Swine health
TL;DR: Results suggest that farm of origin can affect microbial diversity and composition of sows under field conditions, and sow’s health status may have an impact on the nasal microbiota composition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 8, 2021

2021 article

Correlation of cytology to histology in a case of canine granulomatous colitis in a Boxer dog

Sims, C. S., Nagle, J., Tolbert, M. K., Anderson, K., Linder, K., & Neel, J. (2021, October 18). VETERINARY CLINICAL PATHOLOGY, Vol. 10.

By: C. Sims n, J. Nagle n, M. Tolbert*, K. Anderson n, K. Linder n & J. Neel n

author keywords: Boxer dog; canine; colitis; Escherichia coli; histiocytic colitis; rectal cytology; ulcerative colitis
MeSH headings : Animals; Crohn Disease / veterinary; Dog Diseases / diagnosis; Dogs; Hospitals, Animal; Hospitals, Teaching; In Situ Hybridization, Fluorescence / veterinary; Male
TL;DR: The cytology was helpful in identifying features consistent with granulomatous colitis and prioritizing the differential diagnoses and diagnostic plan and is the first published description of the cytologic features of this uncommon disease, offering a valuable cytologic-histologic correlation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: November 1, 2021

2021 journal article

Altrenogest during early pregnancy modulates uterine glandular epithelium and endometrial growth factor expression at the time implantation in pigs

ANIMAL REPRODUCTION, 18(1).

By: B. Muro*, D. Leal*, R. Carnevale*, M. Torres, M. Mendonca*, D. Nakasone*, C. Garcia Martinez*, G. Ravagnani* ...

author keywords: corpus luteum; endometrium; gilts; IGF-I; progesterone
TL;DR: In conclusion, altrenogest improves the uterine environment during the peri-implantation period in pigs without compromising corpora lutea development. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 1, 2021

2021 journal article

A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation

FRONTIERS IN ONCOLOGY, 11.

By: T. Allen*, M. Cullen*, N. Hawkey*, H. Mochizuki n, L. Nguyen, E. Schechter*, L. Borst n, J. Yoder n ...

author keywords: angiopellosis; circulating tumor cell cluster; tumor cell extravasation; cancer exodus hypothesis; metastasis; osteosarcoma
TL;DR: Together, the results provide a novel experimental framework to study discrete steps in the metastatic process and identify the versican/ECM network dysregulation as a potential contributor to osteosarcoma circulating tumor cell metastasis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2021

2021 article

Characterization of Md5-BAC-REV-LTR virus as Marek's disease vaccine in commercial meat-type chickens: protection and immunosuppression

Ellington, C., Cortes, A. L., Faiz, N. M., Mays, J. K., Fadly, A., Silva, R. F., & Gimeno, I. M. (2021, October 9). AVIAN PATHOLOGY, Vol. 10.

By: C. Ellington n, A. Cortes n, N. Faiz n, J. Mays, A. Fadly, R. Silva, I. Gimeno n

author keywords: Marek's disease; vaccination; immunosuppression; LTR; recombinant vaccines; control
MeSH headings : Animals; Chickens; Herpesvirus 2, Gallid; Immunosuppression Therapy / veterinary; Marek Disease Vaccines / genetics; Meat; Reticuloendotheliosis virus; Terminal Repeat Sequences / genetics
TL;DR: It is shown that Md5-BAC-REV-LTR has the potential to be used as a MD vaccine and is highly protective against early challenge with vv+ MDV in commercial meat-type chickens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2021

2021 journal article

Effect of methionine chelated Zn and Mn and corn particle size on Large White male turkey live performance and carcass yields

POULTRY SCIENCE, 100(11).

By: K. Flores n, A. Fahrenholz n, P. Ferket n, T. Biggs & J. Grimes n

author keywords: turkey; zinc; manganese; chelate; carcass yield
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet / veterinary; Dietary Supplements; Manganese; Methionine; Particle Size; Turkeys; Zea mays; Zinc
TL;DR: Increasing the corn mean particle size and adding it post pellet could save money during feed milling; however, birds might have a slightly lower BW and a combination of inorganic and chelated Zn and Mn may improve performance and increase total breast meat yields. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: October 18, 2021

2021 article

Simultaneous primary hyperparathyroidism and multiple myeloma in a dog with hypercalcaemia

Sztukowski, K., Gin, T., Neel, J., & Lunn, K. (2021, October 5). VETERINARY RECORD CASE REPORTS, Vol. 10.

Contributors: K. Sztukowski n, T. Gin n, J. Neel n & K. Lunn n

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 18, 2021

2021 journal article

Mechanisms of Colonization Resistance Against Clostridioides difficile

JOURNAL OF INFECTIOUS DISEASES, 223, S194–S200.

By: C. Pike n & C. Theriot n

author keywords: bacteria; bile acids; Clostridioides difficile; microbiota; short-chain fatty acids
MeSH headings : Animals; Anti-Bacterial Agents / immunology; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / therapeutic use; Antibiosis; Bile Acids and Salts / immunology; Bile Acids and Salts / metabolism; Clostridioides difficile / drug effects; Clostridioides difficile / growth & development; Clostridioides difficile / metabolism; Clostridium Infections / drug therapy; Clostridium Infections / immunology; Clostridium Infections / microbiology; Fatty Acids, Volatile / immunology; Fatty Acids, Volatile / metabolism; Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / physiology; Humans; Nutrients / immunology; Nutrients / metabolism
TL;DR: Commensal gut microbes are critical for providing colonization resistance against C. difficile, and can be leveraged as non-antibiotic alternative therapeutics for the prevention and treatment of CDI. (via Semantic Scholar)
Source: Web Of Science
Added: October 18, 2021

2021 journal article

Comparison of the Intestinal Pharmacokinetics of Two Different Florfenicol Dosing Regimens and Its Impact on the Prevalence and Phenotypic Resistance of E. coli and Enterococcus over Time

MICROORGANISMS, 9(9).

By: J. Halleran n, R. Minch n, H. Slyvester n, M. Jacob n, T. Prange n, R. Baynes n, D. Foster n

author keywords: antimicrobials resistance; cattle; gastrointestinal pharmacokinetics
TL;DR: There was no significant difference noted between dosing groups in proportion or persistence of phenotypically resistant bacterial isolates; however, the percent of resistant isolates was high throughout the study period. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 12, 2021

2021 article

Non-cardiogenic pulmonary oedema and multisystemic haemorrhage secondary to an accidental intravenous injection of melarsomine in a dog

Wolf, J., Law, J. M., & Lynch, A. (2021, September 29). VETERINARY RECORD CASE REPORTS.

By: J. Wolf n, J. Law n & A. Lynch n

author keywords: canine; dirofilariasis treatment; drug error
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 12, 2021

2021 journal article

Host–Pathogen Interactions of <i>Chlamydia trachomatis</i> in Porcine Oviduct Epithelial Cells

Pathogens, 10(10), 1270.

By: A. Amaral n, B. McQueen*, K. Bellingham-Johnstun n, T. Poston*, T. Darville*, U. Nagarajan*, C. Laplante n, T. Kaeser

author keywords: Chlamydia trachomatis; porcine oviduct epithelial cell; developmental cycle; innate immune response; claudin-4; tight junctions
TL;DR: It is shown that primary pOECs represent an excellent in vitro model for research into Ct pathogenesis, cell biology and immunity and induces an immune response to Ct similar to human cells. (via Semantic Scholar)
Source: ORCID
Added: October 6, 2021

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