Works Published in 2007

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Displaying works 41 - 60 of 79 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2007 journal article

Aptameric enzyme subunit for homogeneous protein sensing.

Nucleic Acids Symposium Series (2004), (51), 99–100. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:18029605&KeyUID=MEDLINE:18029605

By: W. Yoshida, K. Sode & K. Ikebukuro

Contributors: W. Yoshida, K. Sode & K. Ikebukuro

Source: ORCID
Added: October 9, 2020

2007 journal article

A novel wireless glucose sensor employing direct electron transfer principle based enzyme fuel cell

Biosensors & Bioelectronics, 22(9-10), 2250–2255.

By: N. Kakehi*, T. Yamazaki*, W. Tsugawa* & K. Sode*

Contributors: N. Kakehi*, T. Yamazaki*, W. Tsugawa* & K. Sode*

author keywords: glucose dehydrogenase; continuous glucose monitoring; bio-fuel cell; glucose sensor; direct electron transfer
MeSH headings : Animals; Biosensing Techniques / instrumentation; Burkholderia cepacia / enzymology; Cattle; Glucose / analysis; Glucose 1-Dehydrogenase
TL;DR: This is the first demonstration of an enzyme-based direct electron transfer-type enzyme fuel cell and fuel cell-type glucose sensor which can be utilized as a subcutaneously implantable system for continuous glucose monitoring. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: October 9, 2020

2007 journal article

A low cost instrumented glove for extended monitoring and functional hand assessment

Journal of Neuroscience Methods, 160(2), 335–348.

By: L. Simone*, N. Sundarrajan*, X. Luo*, Y. Jia* & D. Kamper*

author keywords: electro goniometry; finger flexion; hand function; functional outcome measures; wireless monitoring
MeSH headings : Adult; Aged; Cost-Benefit Analysis; Disability Evaluation; Electrodes / trends; Electrodiagnosis / economics; Electrodiagnosis / instrumentation; Electrodiagnosis / methods; Electrophysiology / economics; Electrophysiology / instrumentation; Electrophysiology / methods; Equipment and Supplies / economics; Equipment and Supplies / standards; Feasibility Studies; Feedback / physiology; Female; Fingers / physiopathology; Gloves, Protective / economics; Hand / physiopathology; Humans; Male; Middle Aged; Monitoring, Physiologic / economics; Monitoring, Physiologic / instrumentation; Monitoring, Physiologic / methods; Movement / physiology; Movement Disorders / diagnosis; Movement Disorders / physiopathology; Predictive Value of Tests; Telemetry / economics; Telemetry / instrumentation; Telemetry / methods
TL;DR: A wearable finger flexion monitor developed to measure hand function in individuals with hand dysfunction was evaluated for feasibility, measurement repeatability and reliability, fidelity of wireless transmission, and user acceptance to demonstrate that the monitor has a strong potential to be used as a tool for objective hand function evaluation in the home and community. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2007 journal article

Chitosan solution enhances the immunoadjuvant properties of GM-CSF

Vaccine, 25(52), 8673–8686.

By: D. Zaharoff*, C. Rogers*, K. Hance*, J. Schlom* & J. Greiner*

author keywords: chitosan; immunoadjuvant; GM-CSF; controlled release; cytokine
MeSH headings : Adjuvants, Immunologic / administration & dosage; Animals; Antigen Presentation / immunology; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Cell Proliferation; Chitosan / immunology; Cytotoxicity Tests, Immunologic; Delayed-Action Preparations / administration & dosage; Dendritic Cells / immunology; Female; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor / administration & dosage; Granulocyte-Macrophage Colony-Stimulating Factor / immunology; Histocompatibility Antigens Class II / genetics; Injections, Subcutaneous; Lymph Nodes / immunology; Lymphocyte Subsets / immunology; Mice; T-Lymphocytes, Cytotoxic / immunology
TL;DR: Chitosan/rGM- CSF outperformed standard rGM-CSF administrations in dendritic cell recruitment, antigen presentation and vaccine enhancement and was superior to either chitOSan or rGM -CSF alone in enhancing the induction of antigen-specific CD4(+) proliferation, peptide- specific CD8(+) pentamer staining and cytotoxic T cell lysis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2007 journal article

Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination

Vaccine, 25(11), 2085–2094.

By: D. Zaharoff*, C. Rogers*, K. Hance*, J. Schlom* & J. Greiner*

author keywords: adjuvant; depot; vaccination
MeSH headings : Adjuvants, Immunologic; Aluminum Hydroxide / immunology; Animals; Antibodies / blood; CD4-Positive T-Lymphocytes / immunology; Chitosan / immunology; Chitosan / pharmacokinetics; Enzyme-Linked Immunosorbent Assay; Female; Freund's Adjuvant; Histocytochemistry; Hypersensitivity, Delayed; Injections, Subcutaneous; Lipids; Lymph Nodes / cytology; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Models, Animal; Skin / pathology; Vaccination; Vaccines / administration & dosage; Vaccines / immunology; beta-Galactosidase / immunology
TL;DR: Mechanistic studies demonstrate that chitosan is a promising and safe platform for parenteral vaccine delivery and at least two characteristics that may allow it to function as an immune adjuvant. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2007 journal article

Electric field-mediated transport of plasmid DNA in tumor interstitium in vivo

Bioelectrochemistry, 71(2), 233–242.

By: J. Henshaw*, D. Zaharoff*, B. Mossop* & F. Yuan*

author keywords: in vivo DNA electrophoresis; interstitial transport; non-viral gene therapy; DNA electrotransfer; electric field-mediated gene delivery
MeSH headings : Animals; Azo Compounds; Biological Transport, Active; Cell Line, Tumor; Collagen; DNA, Neoplasm / genetics; DNA, Neoplasm / metabolism; Electrodes; Electrophoresis; Eosine Yellowish-(YS); Fluorescent Dyes; Mammary Neoplasms, Experimental / genetics; Mammary Neoplasms, Experimental / metabolism; Melanoma, Experimental / genetics; Melanoma, Experimental / metabolism; Methyl Green; Mice; Microscopy, Confocal; Plasmids / genetics; Plasmids / metabolism; Rhodamines
Source: Crossref
Added: August 28, 2020

2007 journal article

Blind Laboratory Trials for Multiple Pathogens in Spiked Food Matrices

Analytical Letters, 40(17), 3219–3231.

By: L. Shriver‐Lake*, J. Erickson*, K. Sapsford*, M. Ngundi*, K. Shaffer*, N. Kulagina, J. Hu*, S. Gray* ...

author keywords: immunosensor; biosensor; salmonella; SEB; pathogen detection
Source: Crossref
Added: August 28, 2020

2007 journal article

Binding and Neutralization of Lipopolysaccharides by Plant Proanthocyanidins

Journal of Natural Products, 70(11), 1718–1724.

MeSH headings : Camellia sinensis / chemistry; Humans; Lipopolysaccharides / metabolism; Molecular Structure; NF-kappa B / metabolism; Proanthocyanidins / chemistry; Proanthocyanidins / isolation & purification; Proanthocyanidins / pharmacology; Vaccinium macrocarpon / chemistry; Vitis / chemistry
TL;DR: The binding of PACs from cranberries, tea, and grapes to lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria and the cause of several human illnesses, is analyzed to suggest that they have potential utility in applications that necessitate either the purification and removal of LPS or the in vivo neutralization of L PS. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2007 journal article

Combination of Immunosensor Detection with Viability Testing and Confirmation Using the Polymerase Chain Reaction and Culture

Analytical Chemistry, 79(1), 140–146.

By: B. Johnson-White, B. Lin* & F. Ligler*

MeSH headings : Bacillus subtilis / growth & development; Bacillus subtilis / isolation & purification; Bacillus subtilis / pathogenicity; Bacteria / classification; Bacteria / growth & development; Bacteria / isolation & purification; Bacteria / pathogenicity; Biosensing Techniques; Cell Culture Techniques / methods; Colony Count, Microbial; Electrophoresis / methods; Escherichia coli / growth & development; Escherichia coli / isolation & purification; Escherichia coli / pathogenicity; Food Microbiology; Immunoassay; Polymerase Chain Reaction / methods; Sensitivity and Specificity
TL;DR: This study combines the rapid screening capability of the array biosensor using an immunoassay format with methods for determination of viability, and demonstrates analysis of captured bacteria using the polymerase chain reaction (PCR). (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2007 journal article

Antimicrobial peptides as new recognition molecules for screening challenging species

Sensors and Actuators B: Chemical, 121(1), 150–157.

By: N. Kulagina, K. Shaffer*, F. Ligler* & C. Taitt*

author keywords: antimicrobial peptides; Coxiella burnetti; Brucella melitensis; vaccinia virus; Venezuelan equine encephalitis virus; screening
TL;DR: Direct binding experiments demonstrate the capability of AMPs as recognition molecules for four biothreat agents in biosensor assays and contrast to all bacterial targets tested to date. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Crossref
Added: August 28, 2020

2007 journal article

Target delivery in a microfluidic immunosensor

Biosensors and Bioelectronics, 22(11), 2763–2767.

By: J. Golden*, T. Floyd-Smith*, D. Mott* & F. Ligler*

author keywords: mixer; grooves; microchannels; fluorescence; immunoassay; depletion
MeSH headings : Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Botulinum Toxins / analysis; Botulinum Toxins / immunology; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Equipment Design; Equipment Failure Analysis; Fluoroimmunoassay / instrumentation; Fluoroimmunoassay / methods; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Reproducibility of Results; Sensitivity and Specificity
TL;DR: Patterned grooves were embossed in the top of microchannels made in PDMS using soft lithography, enhancing delivery of the target from the bulk fluid to the surface and preventing the formation of a depletion layer at the surface. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Crossref
Added: August 28, 2020

2007 journal article

Laser ablation of micropores for formation of artificial planar lipid bilayers

Biomedical Microdevices, 9(6), 863–868.

By: T. O’Shaughnessy*, J. Hu*, J. Kulp*, S. Daly* & F. Ligler*

author keywords: lipid bilayer; aperture; laser ablation; ion channel recording
MeSH headings : Biomimetic Materials / chemistry; Biomimetic Materials / radiation effects; Lasers; Lipid Bilayers / chemistry; Lipid Bilayers / radiation effects; Materials Testing; Membranes, Artificial; Molecular Conformation; Polycarboxylate Cement / chemistry; Polycarboxylate Cement / radiation effects; Porosity
TL;DR: The data demonstrate that the apertures produced by laser ablation are highly reproducible and can support both the formation of stable, long-lasting lipid bilayers as well as the recording of ion channels incorporated into the bilayers. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2007 journal article

Automated module for hybridization and staining of commercially produced nucleic acid microarrays

Microfluidics and Nanofluidics, 3(5), 623–628.

By: J. Erickson*, J. Hu*, G. Anderson*, A. Salls*, S. Gray*, J. Golden*, B. Lin*, F. Ligler*

author keywords: microarray; hybridization; automated; diagnostics; portable
TL;DR: A portable module is demonstrated that can perform the hybridization, wash, and stain steps required for processing a nucleic acid microarray; and it performs these steps in a timeline significantly shorter than the standard commercial protocol. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2007 journal article

Effects of Molecular Structure and Interfacial Ligation on the Precision of Cu-Bound α,ω-Mercaptoalkanoic Acid “Molecular Ruler” Stacks

Langmuir, 23(2), 638–648.

By: T. Daniel*, S. Uppili*, G. McCarty* & D. Allara*

Sources: Crossref, NC State University Libraries
Added: February 5, 2020

2007 journal article

Design and Control of RUPERT: A Device for Robotic Upper Extremity Repetitive Therapy

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 15(3), 336–346.

By: T. Sugar*, J. He*, E. Koeneman, J. Koeneman, R. Herman*, H. Huang*, R. Schultz, D. Herring* ...

Contributors: T. Sugar*, J. He*, E. Koeneman, J. Koeneman, R. Herman*, H. Huang*, R. Schultz, D. Herring* ...

author keywords: control; neuromotor function; pneumatic muscle; rehabilitation robot; repetitive therapy; stroke
MeSH headings : Computer Simulation; Equipment Design; Equipment Failure Analysis; Exercise Therapy / instrumentation; Exercise Therapy / methods; Feedback; Humans; Models, Biological; Movement Disorders / physiopathology; Movement Disorders / rehabilitation; Robotics / instrumentation; Robotics / methods; Stroke / physiopathology; Stroke Rehabilitation; Therapy, Computer-Assisted / instrumentation; Therapy, Computer-Assisted / methods; Upper Extremity / physiopathology
TL;DR: The structural design, control system, and integrated biofeedback for a wearable exoskeletal robot for upper extremity stroke rehabilitation are presented and the device has four actuated degrees-of-freedom driven by compliant and safe pneumatic muscles on the shoulder, elbow, and wrist. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020

2007 journal article

Decoding a New Neural–Machine Interface for Control of Artificial Limbs

Journal of Neurophysiology, 98(5), 2974–2982.

By: P. Zhou, M. Lowery*, K. Englehart*, H. Huang*, G. Li, L. Hargrove*, J. Dewald, T. Kuiken

Contributors: P. Zhou, M. Lowery*, K. Englehart*, H. Huang*, G. Li, L. Hargrove*, J. Dewald, T. Kuiken

MeSH headings : Adult; Amputation, Surgical / rehabilitation; Amputation Stumps / innervation; Artificial Limbs; Electromyography / methods; Female; Humans; Male; Middle Aged; Muscle, Skeletal / innervation; User-Computer Interface
TL;DR: This study indicates that TMR combined with pattern-recognition techniques has the potential to further improve the function of prosthetic limbs and demonstrates that the central motor control system is capable of eliciting complex efferent commands for a missing limb, in the absence of peripheral feedback and without retraining of the pathways involved. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020

2007 journal article

Morphological, electrical, and mechanical characterization of electrospun nanofiber mats containing multiwalled carbon nanotubes

MACROMOLECULES, 40(4), 997–1003.

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Effects of oxygen plasma treatment on adipose-derived human mesenchymal stem cell adherence to poly(L-lactic acid) scaffolds

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 18(11), 1387–1400.

author keywords: hydrophilicity; non-woven PLLA scaffold; cell morphology; cell viability; melt-blown PLLA scaffold
MeSH headings : Adipocytes / cytology; Cell Adhesion / drug effects; Cell Survival; Cells, Cultured; Humans; Lactic Acid / chemistry; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Microscopy, Electron, Scanning; Oxygen / chemistry; Oxygen / pharmacology; Polyesters; Polymers / chemistry; Tissue Scaffolds / chemistry
TL;DR: Enhanced cell adhesion to non-woven poly(L-lactic acid) (PLLA) scaffolds using oxygen plasma treatment to increase surface hydroxyl groups and thereby enhance substrate hydrophilicity was enhanced. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Characterization of electrospun nanocomposite scaffolds and biocompatibility with adipose-derived human mesenchymal stem cells

International Journal of Nanomedicine, 2(2), 253–263.

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Rapid prototyping of ossicular replacement prostheses

Applied Surface Science, 253(15), 6603–6607.

author keywords: two-photon polymerization; rapid prototyping; ossicular replacement prosthesis
TL;DR: The results demonstrate that two-photon polymerization is able to create ossicular replacement prostheses and other medical devices with a larger range of sizes, shapes and materials than other microfabrication techniques. (via Semantic Scholar)
Sources: Crossref, Web Of Science
Added: August 6, 2018

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