Works Published in 2023
Displaying works 41 - 60 of 74 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2023 journal article
Domestic Dogs and Horses as Sentinels of Per- and Polyfluoroalkyl Substance Exposure and Associated Health Biomarkers in Gray's Creek North Carolina
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57(26), 9567–9579.
author keywords: canine; drinking water; equine; fluoroether; One Health; nafion by-product 2; GenX chemicals; PFOA; PFOS
TL;DR:
The utility of companion animal and livestock species as sentinels of PFAS exposure differences inside and outside of the home is supported, as in humans, renal and hepatic health in domestic animals may be sensitive to long-term PFAS exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 21, 2023
2023 journal article
Developmental cadmium exposure disrupts zebrafish vestibular calcium channels interfering with otolith formation and inner ear function
NEUROTOXICOLOGY, 96, 129–139.
author keywords: Cadmium; Developmental toxicology; Behavior; Vestibular system; P2X receptor; Zebrafish
MeSH headings : Animals; Zebrafish; Cadmium / toxicity; Otolithic Membrane; Vestibule, Labyrinth; Vestibular Diseases
TL;DR:
Cadmium-induced ototoxicity is linked to vestibular-based behavioral abnormalities and auditory sensitivity following developmental exposure, and calcium ion channel function is associated with these defects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 12, 2023
2023 article
A chromosome-level genome assembly of longnose gar, Lepisosteus osseus
Mallik, R., Carlson, K. B., Wcisel, D. J., Fisk, M., Yoder, J. A., & Dornburg, A. (2023, April 29). (N. Whiteman, Ed.). G3-GENES GENOMES GENETICS, Vol. 4.
Ed(s): N. Whiteman
author keywords: teleost genome duplication; holostei; longnose gar; chromosome level assembly; living fossil; transposable elements
MeSH headings : Humans; Animals; Evolution, Molecular; Fishes / genetics; Genome; Chromosomes / genetics; Phylogeny
TL;DR:
The first high quality reference genome assembly and annotation of the longnose gar (Lepisosteus osseus) is reported, highlighting the potential utility of holostean genomes for understanding the evolution of vertebrate repetitive elements and providing a critical reference for comparative genomic studies utilizing ray-finned fish models.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 12, 2023
2023 journal article
Pharmacogenomic Analyses Implicate B Cell Developmental Status and MKL1 as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy
CELLS, 12(12).
author keywords: rituximab (Rituxan (R)); ofatumumab (Arzerra (R),& nbsp;Kesimpta (R)); obinutuzumab (Gazyva (R)); CD20 (MS4A1); MKL1 (MRTFA); TGFB1
TL;DR:
Results suggest that the efficacy of anti-CD20 mAb therapy may be influenced by B cell developmental status as well as polymorphism in the MKL1 gene.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 8, 2023
2023 article
Utilizing Aggregated Molecular Phenotype (AMP) Scores to Visualize Simultaneous Molecular Changes in Mass Spectrometry Imaging Data
Chappel, J. R., King, M. E., Fleming, J., Eberlin, L. S., Reif, D. M., & Baker, E. S. (2023, June 5).
TL;DR:
Initial comparisons of cancerous human tissues to normal or benign counterparts illustrated that AMP scores distinguished phenotypes with high accuracy, sensitivity, and specificity, leading to high diagnostic accuracy and interpretability of predictive models.
(via Semantic Scholar)
Source: ORCID
Added: June 6, 2023
2023 journal article
C/EBP beta deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors
INNATE IMMUNITY, 29(1-2), 14–24.
author keywords: C/EBP beta; cell death; keratinocytes; type I IFN response
MeSH headings : Animals; Mice; Caspase 3 / metabolism; Caspase 8 / metabolism; CCAAT-Enhancer-Binding Protein-beta / genetics; Immunity, Innate; Interferon Type I / metabolism; Keratinocytes; Receptors, Pattern Recognition / genetics; Receptors, Pattern Recognition / metabolism
TL;DR:
The conditional deletion of C/EBPβ transcription factor in mouse epidermis resulted in the upregulation of IFNβ and numerous keratinocyte interferon-stimulated genes (ISGs) and the expression of cytosolic pattern recognition receptors (cPRRs), that recognize viral RNA and DNA, were significantly increased, and enriched in the RNAseq data set.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023
2023 article
Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern
Arnold, W. A. ., Blum, A., Branyan, J., Bruton, T. A. ., Carignan, C. C., Cortopassi, G., … Zheng, G. (2023, May 8). ENVIRONMENTAL SCIENCE & TECHNOLOGY.
author keywords: antimicrobial resistance; policy; essential use; regrettable substitution; surfactants; disinfectants; surface coatings; COVID-19; personal care products; softeners; antistatic agents
MeSH headings : Humans; Quaternary Ammonium Compounds / chemistry; Pandemics; COVID-19; Anti-Bacterial Agents; Disinfectants
TL;DR:
A critical review of the literature and scientific perspective developed by a multidisciplinary, multi-institutional team of authors provides research and policy recommendations for preserving the utility of QAC chemistries while also seeking to limit adverse environmental and human health effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 22, 2023
2023 journal article
MKX-AS1 Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients
PHARMACEUTICALS, 16(5).
author keywords: precision medicine; colorectal cancer; pharmacogenomics; oxaliplatin; lncRNA's; antisense
TL;DR:
An association between MKX-AS1 and MKX expression status that could be useful as a prognostic marker of response to OXAL and potential patient outcomes in CRC is suggested.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 19, 2023
2023 article
Time of acquisition and high spatial resolution mass spectrometry imaging (vol 58, e4911, 2023)
Muddiman, D. C. (2023, May). JOURNAL OF MASS SPECTROMETRY, Vol. 58.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 15, 2023
2023 article
On the importance of color in mass spectrometry imaging (vol 57, e4898, 2022)
Muddiman, D. C. (2023, May). JOURNAL OF MASS SPECTROMETRY, Vol. 58.
Sources: Web Of Science, NC State University Libraries
Added: May 15, 2023
2023 article
Achieving Sub-Parts-per-Million Mass Measurement Accuracy on an Orbitrap Mass Spectrometry Imaging Platform without Automatic Gain Control
Kibbe, R. R., & Muddiman, D. C. (2023, April 25). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 4.
author keywords: centroid; mass measurement accuracy; IR-MALDESI; mass spectrometry imaging; Orbitrap; automatic gain control
MeSH headings : Animals; Mice; Mass Spectrometry / methods; Data Accuracy; Lipids
TL;DR:
There is support that natively collecting centroid MS data significantly improves MMA to sub-ppm levels without AGC and reduces false positive annotations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 15, 2023
2023 journal article
RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients
PHARMACEUTICALS, 16(5).
author keywords: GWAS; chemotherapy; sensitivity; resistance; glioma; drug response; temozolomide; knockdown; overexpression; pharmacogenomics; gene expression; RYK
TL;DR:
The findings suggest that RYK expression may serve as an important prognostic or predictor of TMZ response and survival for glioma patients and a combination of RyK expression and MGMT status could serve as a additional biomarker for improved survival.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 12, 2023
2023 journal article
Physiological and life history responses in a mayfly (Callibaetis floridanus) inhabiting ponds with saltwater intrusion
FRONTIERS IN ECOLOGY AND EVOLUTION, 11.
author keywords: mayfly; saline adaptation; ion fluxes; saltwater intrusion; plasticity
TL;DR:
Analysis of life-history outcomes and physiological plasticity in a population of Callibaetis floridanus from a coastal pond that routinely experiences saltwater intrusion suggests that saline adapted C. floridas may be more energetically challenged in dilute conditions, which differs from previous observations in other mayfly species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: May 1, 2023
2023 article
Lipidomic Analysis of Mouse Brain to Evaluate the Efficacy and Preservation of Different Tissue Preparatory Techniques by IR-MALDESI-MSI
Wang, M. F., Sohn, A. L., Samal, J., Erning, K., Segura, T., & Muddiman, D. C. (2023, March 29). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 3.
author keywords: IR-MALDESI; mass spectrometry imaging; sucrose; PFA
MeSH headings : Mice; Animals; Spectrometry, Mass, Electrospray Ionization / methods; Lipidomics; Ice; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Ions / chemistry; Lipids / analysis; Brain
TL;DR:
Evidence from these investigations supports sucrose-embedding without ice matrix as an alternative preparatory technique for IR-MALDESI-MSI, and demonstrates improved spatial distribution of ions resulting from the cryo-protective property of sucrose and paraformaldehyde fixation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 24, 2023
2023 article
Predicting Concentration- and Ionic-Strength-Dependent Air-Water Interfacial Partitioning Parameters of PFASs Using Quantitative Structure-Property Relationships (QSPRs)
Stults, J. F., Choi, Y. J., Rockwell, C., Schaefer, C. E., Nguyen, D. D., Knappe, D. R. U., … Higgins, C. P. (2023, March 24). ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol. 3.
author keywords: PFAS air-water interfacial adsorption; QSPR; nonequilibrium; unsaturated columns; pan film
MeSH headings : Water; Fluorocarbons / analysis; Ethers; Alkanesulfonic Acids; Water Pollutants, Chemical / analysis; Osmolar Concentration
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 17, 2023
2023 article
Ancient Fish Lineages Illuminate Toll-Like Receptor Diversification in Early Vertebrate Evolution
Carlson, K. B., Nguyen, C., Wcisel, D. J., Yoder, J. A., & Dornburg, A. (2023, April 6).
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: April 7, 2023
2023 article
Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut
Foley, M. H., Walker, M. E., Stewart, A. K., O'Flaherty, S., Gentry, E. C., Patel, S., … Theriot, C. M. (2023, March 13). NATURE MICROBIOLOGY, Vol. 3.
MeSH headings : Animals; Mice; Humans; Clostridioides difficile; Clostridioides; Bile Acids and Salts; Amidohydrolases; Clostridium Infections
TL;DR:
Insight is provided into the structural basis of BSH mechanisms that shape the BA landscape and promote colonization resistance against C. difficile in vitro and in pre-clinical in vivo models of CDI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023
2023 article
Impact of wavelength and spot size on laser depth of focus: Considerations for mass spectrometry imaging of non-flat samples
Joignant, A. N. N., Xi, Y., & Muddiman, D. C. C. (2023, March 14). JOURNAL OF MASS SPECTROMETRY, Vol. 3.
author keywords: depth of focus; laser wavelength; mass spectrometry imaging; spatial resolution; surface roughness
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023
2023 article
Landfill Codisposal of On-Site Vegetation and Coal Combustion Residuals: Implications for Gas Management
Cruz, F., Setz, M., Barlaz, M., & Varsho, J. (2023, March 17). ACS ES&T ENGINEERING, Vol. 3.
author keywords: CCR; ash; landfill; methane; remediation
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 18, 2023
2023 journal article
Pilot-scale biofiltration of 1,4-dioxane at drinking water-relevant concentrations
WATER RESEARCH, 231.
author keywords: Biofiltration; Cometabolism; Adsorption; Emerging contaminants
MeSH headings : Drinking Water; Pilot Projects; Water Pollutants, Chemical / analysis; Water Purification / methods; Charcoal / chemistry; Filtration / methods
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 13, 2023
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