Works Published in 2002
Displaying works 21 - 40 of 47 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2002 journal article
Genistein Affects ERβ- But Not ERα-Dependent Gene Expression in the Hypothalamus
Endocrinology, 143(6), 2189–2197.
MeSH headings : Animals; Autoradiography; Brain Chemistry / drug effects; Diet; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens / blood; Estrogens, Non-Steroidal / blood; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression Regulation / drug effects; Genistein / blood; Genistein / pharmacology; Hypothalamus / drug effects; Hypothalamus / metabolism; In Situ Hybridization; Male; RNA, Messenger / biosynthesis; Radioimmunoassay; Rats; Rats, Long-Evans; Receptors, Estrogen / biosynthesis; Receptors, Estrogen / genetics; Receptors, Oxytocin / drug effects; Receptors, Oxytocin / metabolism; Sexual Behavior, Animal / drug effects; Sexual Maturation / physiology; Uterus / drug effects; Uterus / growth & development
TL;DR:
The impact of the soy isoflavone genistein, a major component of the supplement, on estrogen-dependent female sexual behavior and ERα- and ERβ-dependent gene expression in the rat brain is examined.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2002 review
Zebrafish as an immunological model system
[Review of ]. MICROBES AND INFECTION, 4(14), 1469–1478.
author keywords: mutation screens; zebrafish genome project; transgenesis; developmental immunology; novel immune-type genes
MeSH headings : Animals; Fish Diseases / immunology; Immunity, Active / genetics; Immunity, Innate / physiology; Killer Cells, Natural / immunology; Models, Animal; Models, Immunological; Mutagenesis; Transgenes; Zebrafish / genetics; Zebrafish / immunology
TL;DR:
Two decades of research have established the zebrafish as a significant model system for studying vertebrate development and gene structure-function relationships and recent advances in mutation screening, the creation of genomic resources, and the development of efficient transgenesis procedures make this model increasingly attractive for immunological study.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Cloning novel immune-type inhibitory receptors from the rainbow trout, Oncorhynchus mykiss
Immunogenetics, 54(9), 662–670.
TL;DR:
A comprehensive, phylogenetic analysis of NITRs from rainbow trout and three other major lineages of bony fish defines conserved families of N ITRs and suggests an ancient lineage of distinct groups of genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2002 journal article
BIVM, a Novel Gene Widely Distributed among Deuterostomes, Shares a Core Sequence with an Unusual Gene in Giardia lamblia
Genomics, 79(6), 750–755.
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 13; Conserved Sequence; Gene Transfer, Horizontal; Genome, Human; Giardia lamblia / genetics; Humans; Immunoglobulins / genetics; Mice; Molecular Sequence Data; Organ Specificity; Protozoan Proteins; Vertebrates / genetics
TL;DR:
Characterization of BIVM in representative species demonstrates significant conservation throughout deuterostomes; however, an unusual gene has been identified in the protozoan pathogen Giardia lamblia that is similar to the core sequence of B IVM, suggesting the possibility of a horizontal gene transfer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2002 patent
Electrochemical detection of nucleic acid sequences
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Physicochemical determinants of linear alkylbenzene sulfonate (LAS) disposition in skin exposed to aqueous cutting fluid mixtures
TOXICOLOGY AND INDUSTRIAL HEALTH, 18(5), 237–248.
author keywords: cutting fluids; LAS; mixtures; physicochemical interactions; skin
MeSH headings : Alkanesulfonic Acids / chemistry; Alkanesulfonic Acids / pharmacokinetics; Alkanesulfonic Acids / toxicity; Animals; Dermatitis, Contact / etiology; Metallurgy; Mineral Oil / pharmacology; Occupational Exposure; Permeability; Polyethylene Glycols / pharmacology; Skin Absorption / drug effects; Solubility; Solvents / pharmacology; Surface-Active Agents / chemistry; Surface-Active Agents / pharmacokinetics; Surface-Active Agents / toxicity; Swine
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Developmental toxicity of testosterone in the crustacean Daphnia magna involves anti-ecdysteroidal activity
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 129(2), 127–133.
MeSH headings : Animals; Crustacea / drug effects; Crustacea / embryology; Crustacea / growth & development; Ecdysteroids / antagonists & inhibitors; Ecdysterone / pharmacology; Embryo, Nonmammalian / drug effects; Gonadal Steroid Hormones / poisoning; Molting / drug effects; Testosterone / poisoning
TL;DR:
It is demonstrated that ecdysteroids regulate critical processes in daphnid embryo development and testosterone elicits embryo toxicity todaphnids by interfering with Ecdysteroid activity, and that ecdysone receptor antagonism could be one mechanism by which testosterone elicited these effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Gulf War related exposure factors influencing topical absorption of C-14-permethrin
TOXICOLOGY LETTERS, 135(1-2), 61–71.
author keywords: permethrin; Gulf War; JP-8; jet fuel; sulfur mustard; skin; absorption
MeSH headings : Animals; Cholinesterase Inhibitors; DEET / toxicity; Dermatologic Agents / pharmacology; Dermatologic Agents / toxicity; Environmental Exposure / adverse effects; Humans; Hydrocarbons / toxicity; In Vitro Techniques; Insect Repellents / toxicity; Insecticides / pharmacokinetics; Insecticides / toxicity; Isoflurophate / toxicity; Mustard Gas / toxicity; Permethrin / pharmacokinetics; Permethrin / toxicity; Persian Gulf Syndrome / chemically induced; Skin / drug effects; Skin / metabolism; Skin Absorption / physiology; Swine
TL;DR:
It is suggested that co-exposure to JP-8 or sulfur mustard may modulate transdermal flux of 14C-permethrin and this moderate increase in permethrin absorption remains unclear.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Extrapolated withdrawal-interval estimator (EWE) algorithm: A quantitative approach to establishing extralabel withdrawal times
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 36(1), 131–137.
author keywords: extralabel; withdrawal interval; Extrapolated Withdrawal-Interval Estimator Algorithm; residues; population pharmacokinetics
MeSH headings : Algorithms; Animals; Animals, Domestic / metabolism; Drug Residues / pharmacokinetics; Half-Life; Legislation, Drug; Legislation, Veterinary; Models, Biological; Time Factors; United States; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
TL;DR:
The present study introduces and validates with simulated and experimental data the Extrapolated Withdrawal-Period Estimator (EWE) Algorithm, a procedure aimed at predicting extralabel withdrawal intervals (WDIs) based on the label and pharmacokinetic literature data contained in the Food Animal Residue Avoidance Databank (FARAD).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
17 beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice
TOXICOLOGICAL SCIENCES, 69(1), 42–48.
author keywords: mirex; skin; 17 beta-estradiol; tumor promotion; endocrine
MeSH headings : Animals; Carcinogens / toxicity; Cell Line; Chlordecone / toxicity; Drug Implants; Estradiol / administration & dosage; Estradiol / pharmacology; Female; Genes, Reporter / drug effects; Insecticides / toxicity; Luciferases / biosynthesis; Male; Mice; Mirex / toxicity; Orchiectomy; Ovariectomy; Radioimmunoassay; Sex Characteristics
TL;DR:
Collectively, these studies indicate that E2 is a major ovarian hormone responsible for mirex tumor promotion sensitivity in female mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(1), 207–212.
MeSH headings : 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Bromodeoxyuridine / pharmacology; CCAAT-Enhancer-Binding Protein-beta / genetics; CCAAT-Enhancer-Binding Protein-beta / metabolism; CCAAT-Enhancer-Binding Protein-beta / physiology; Carcinogens; Cell Division; Cell Survival; Genes, Reporter; Keratinocytes / cytology; Keratinocytes / metabolism; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases / metabolism; Mutagens; Mutation; Oncogene Protein p21(ras) / genetics; Oncogene Protein p21(ras) / physiology; Phosphorylation; Signal Transduction; Skin Neoplasms / metabolism; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation
TL;DR:
It is reported here that C/EBPβ-nullizygous mice are completely refractory to skin tumor development induced by a variety of carcinogens and carcinogenesis protocols, including 7,12-dimethylbenz[a]anthracene-initiation/12-O-tetradecanoylphorbol 13-acetate promotion, that produce tumors containing oncogenic Ras mutations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis
MECHANISMS OF DEVELOPMENT, 119(2), 239–249.
author keywords: bone morphogenetic protein; mitogen-activated protein kinase; mouse; signal transduction; TGF-beta activated kinase-1 binding protein-1; TGF-beta activated kinase-1; transforming growth factor-beta
MeSH headings : Adaptor Proteins, Signal Transducing; Alleles; Amino Acid Sequence; Animals; Blotting, Western; Cell Differentiation; Cell Division; Cloning, Molecular; Genotype; HIV Envelope Protein gp120 / genetics; HIV Envelope Protein gp120 / physiology; Heart / embryology; Homozygote; Humans; Immunoblotting; In Situ Hybridization; Luciferases / metabolism; Lung / embryology; MAP Kinase Kinase Kinases / metabolism; Mice; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides, Antisense / pharmacology; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / physiology; Recombination, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Tissue Distribution; Transfection; Transforming Growth Factor beta / metabolism
TL;DR:
A possibility that TAB1 plays an important role in mammalian embryogenesis and is required for TAK1 activation in TGF-beta signaling is indicated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Juvenoid hormone methyl farnesoate is a sex determinant in the crustacean Daphnia magna
JOURNAL OF EXPERIMENTAL ZOOLOGY, 293(7), 736–739.
MeSH headings : Animals; Daphnia / drug effects; Daphnia / embryology; Daphnia / growth & development; Daphnia / physiology; Environment; Fatty Acids, Unsaturated / administration & dosage; Fatty Acids, Unsaturated / pharmacology; Female; Juvenile Hormones / administration & dosage; Juvenile Hormones / pharmacology; Male; Reproduction; Sex Differentiation / drug effects; Time Factors
TL;DR:
Results demonstrate that methyl farnesoate is capable of programming daphnid embryos to develop into males and is likely the endocrine factor responsible for initiating the sexual reproductive phase in these organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
13. Climate Action
(Web of Science)
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Effects of prenatal testosterone propionate on the sexual development of male and female rats: A dose-response study
TOXICOLOGICAL SCIENCES, 65(1), 71–86.
author keywords: testosterone propionate; androgens; masculinization; prenatal exposure; sexual differentiation; anogenital distance; agenesis of the lower vagina; Sprague-Dawley rats
MeSH headings : Abnormalities, Drug-Induced / etiology; Anal Canal / abnormalities; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Genitalia, Female / abnormalities; Genitalia, Male / abnormalities; Gonadal Steroid Hormones / administration & dosage; Gonadal Steroid Hormones / physiology; Gonadal Steroid Hormones / toxicity; Male; Maternal Exposure / adverse effects; Nipples / abnormalities; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Testosterone / administration & dosage; Testosterone / physiology; Testosterone / toxicity; Toxicity Tests; Vagina / abnormalities
TL;DR:
Gestation administration of 0.5 and 1 mg TP masculinizes female offspring without greatly affecting pup viability or pregnancy of the dam, and this study provides a useful model for in utero testing of environmental androgens for their potential to induce developmental abnormalities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport
TOXICOLOGICAL SCIENCES, 69(2), 295–305.
author keywords: pentachorophenol; mixtures; interactions; skin; absorption; surfactants; vehicle
MeSH headings : Animals; Chemical Phenomena; Chemistry, Physical; Diffusion; Ethanol / pharmacology; In Vitro Techniques; Insecticides / chemistry; Insecticides / pharmacokinetics; Insecticides / toxicity; Membranes / metabolism; Nicotinic Acids / pharmacology; Pentachlorophenol / chemistry; Pentachlorophenol / pharmacokinetics; Pentachlorophenol / toxicity; Permeability / drug effects; Pharmaceutical Vehicles; Skin Absorption / drug effects; Sodium Dodecyl Sulfate / pharmacology; Solvents / pharmacology; Viscosity
TL;DR:
It is demonstrated that modification in mixture composition with either a solvent and/or a surfactant can influence PCP diffusion in skin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Analysis of N,N-diethyl-m-toluamide in porcine skin perfusates using solid-phase extraction disks and reversed-phase high-performance liquid chromatography
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 780(1), 45–52.
author keywords: N,N-Diethyl-m-toluamide
MeSH headings : Animals; Chromatography, High Pressure Liquid / methods; DEET / analysis; Insect Repellents / analysis; Permeability; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Skin / chemistry; Swine
TL;DR:
An improved method was developed for determining transdermal diffusion of low levels of DEET following application to an in vitro porcine skin flow-through diffusion cell system and it was determined that DEET permeability in porcines skin was 2.55 x 10(-5)+/-0.54 x 10-5 cm/h.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Simultaneous adsorption of MIB and NOM onto activated carbon - II. Competitive effects
CARBON, 40(12), 2147–2156.
Contributors: G. Newcombe*, J. Morrison *, C. Hepplewhite* & D. Knappe n
author keywords: activated carbon; adsorption properties; surface properties
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Pesticide adsorption by granular activated carbon adsorbers. 2. Effects of pesticide and natural organic matter characteristics on pesticide breakthrough curves
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 36(15), 3432–3438.
Contributors: Y. Matsui *, D. Knappe n, K. Iwaki* & H. Ohira*
MeSH headings : Adsorption; Carbamates / chemistry; Carbon / chemistry; Herbicides / chemistry; Models, Chemical; Molecular Weight; Simazine / chemistry; Water Pollutants, Chemical; Water Purification / methods
TL;DR:
Mechanisms by which NOM affects the adsorption of a nonpolar (simazine) and a polar (asulam) herbicide on activated carbon are elucidated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Pesticide adsorption by granular activated carbon adsorbers. 1. Effect of natural organic matter preloading on removal rates and model simplification
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 36(15), 3426–3431.
Contributors: Y. Matsui *, D. Knappe n & R. Takagi*
MeSH headings : Adsorption; Carbamates / chemistry; Carbon / chemistry; Herbicides / chemistry; Models, Theoretical; Simazine / chemistry; Water Pollutants, Chemical; Water Purification / methods
TL;DR:
The adsorptive removal of periodic spikes of the trace synthetic organic chemicals simazine and asulam from water containing natural organic matter was studied in pilot-scale granular activated carbon (GAC) adsorbers over a period of nearly 3 years.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Effects of activated carbon surface chemistry and pore structure on the adsorption of organic contaminants from aqueous solution
CARBON, 40(12), 2085–2100.
Contributors: L. Li n, P. Quinlivan n & D. Knappe n
author keywords: activated carbon, carbon fibers; chemical treatment, surface treatment; adsorption; adsorption properties, microporosity
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.