Comparative Medicine Institute

Works Published in 2009

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Displaying works 341 - 360 of 632 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2009 journal article

Intestinal Epithelial-Derived TAK1 Signaling Is Essential for Cytoprotection against Chemical-Induced Colitis

PLOS ONE, 4(2).

By: J. Kim n, R. Kajino-Sakamoto n, E. Omori n, C. Jobin * & J. Ninomiya-Tsuji n

MeSH headings : Animals; Apoptosis; Cell Proliferation; Colitis / chemically induced; Colitis / etiology; Cyclooxygenase 2; Dextran Sulfate; Interleukin-6; Intestinal Mucosa / metabolism; MAP Kinase Kinase Kinases / deficiency; MAP Kinase Kinase Kinases / physiology; Mice; Mice, Knockout; Receptors, Tumor Necrosis Factor, Type I / deficiency; Signal Transduction
TL;DR: It is shown that TAK1 is essential for interleukin 1- and bacterial components-induced expression of cytoprotective factors and cell proliferation, which is pivotal for protecting the intestinal epithelium against injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Influence of genetic background on tumor karyotypes: Evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma

CHROMOSOME RESEARCH, 17(3), 365–377.

By: R. Thomas n, H. Wang n, P. Tsai n, C. Langford*, S. Fosmire*, C. Jubala*, D. Getzy*, G. Cutter *, J. Modiano *, M. Breen n

author keywords: microarray; comparative genomic hybridization (CGH); canine; osteosarcoma; chromosome
MeSH headings : Animals; Chromosome Aberrations / veterinary; Comparative Genomic Hybridization; Dog Diseases / genetics; Dogs; Genetic Predisposition to Disease / genetics; Karyotyping / veterinary; Osteosarcoma / genetics; Osteosarcoma / veterinary; Species Specificity
TL;DR: Assessment of a cohort of Golden Retrievers and Rottweilers diagnosed with spontaneous appendicular osteosarcoma reveals significant correlations between breed and tumor karyotypes that are independent of gender, age at diagnosis, and histological classification. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

IDENTIFICATION OF POULTRY MEAT FROM PORK AND BEEF ON THE BASIS OF THE TITIN PEVK REGION USING PCR

JOURNAL OF MUSCLE FOODS, 20(3), 341–351.

By: A. Spychaj*, P. Mozdziak n  & E. Pospiech*

Contributors: A. Spychaj*, P. Mozdziak n  & E. Pospiech*

TL;DR: The data presented in this study suggest that it is possible to detect chicken meat, pork and beef in meat mixtures on the basis of PEVK region by using PCR. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Highly efficient in vitro photodynamic inactivation of Mycobacterium smegmatis

Journal of Antimicrobial Chemotherapy, 64(4), 782–785.

By: E. Feese n & R. Ghiladi n 

Contributors: E. Feese n & R. Ghiladi n 

author keywords: multidrug resistant; TB; photosensitizers
MeSH headings : Colony Count, Microbial; Light; Microbial Viability / radiation effects; Mycobacterium smegmatis / radiation effects; Photosensitizing Agents / pharmacology
TL;DR: The best results demonstrate that PDI of M. smegmatis can achieve a noteworthy 5-6 log unit reduction in cfu (99.999% + viable cell eradication) when cationic PSs are employed in the nanomolar concentration range. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Highlights of the July Issue

American Journal of Respiratory Cell and Molecular Biology, 41(1), 1–2.

By: K. Adler* & S. Matalon

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Highlights of the August issue

American Journal of Respiratory Cell and Molecular Biology, 41(2), 125–126.

By: K. Adler* & S. Matalon

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Gene-drive in age-structured insect populations

Evolutionary Applications, 2(2), 143–159.

By: Y. Huang n, A. Lloyd n , M. Legros n & F. Gould n 

author keywords: assortative mating; fitness cost; genetic control; mosquito; release threshold
TL;DR: It is found that models without age‐structure and mating details can substantially overestimate or underestimate the numbers of engineered insects that must be introduced into a wild population to achieve successful gene‐drive based on the Medea and engineered underdominance mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2009 review

GEOGRAPHIC AND TEMPORAL VARIATION IN MOTH CHEMICAL COMMUNICATION

[Review of ]. EVOLUTION, 63(8), 1987–2003.

By: A. Groot n, O. Inglis n, S. Bowdridge  n, R. Santangelo n, C. Blanco*, J. Lopez *, A. Teran Vargas*, F. Gould n , C. Schal n 

author keywords: Experience; female sex pheromone; Heliothis subflexa; Heliothis virescens; male response; phenotypic plasticity; selection
MeSH headings : Animal Communication; Animals; Female; Male; Mexico; Moths / chemistry; Moths / metabolism; Sex Attractants / chemistry; Sex Attractants / metabolism; United States
TL;DR: The pattern of temporal variation within populations suggests that optimization of the pheromonal signal also may be driven by within-generation physiological adjustments by the moths in response to their experience of the local chemical environment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Frequency of Bt Resistance Alleles in H-armigera During 2006-2008 in Northern China

ENVIRONMENTAL ENTOMOLOGY, 38(4), 1336–1342.

By: Y. Gao, K. Wu & F. Gould* 

author keywords: Cry1Ac; Helicoverpa armigera; Bt cotton; resistance frequency
MeSH headings : Alleles; Animals; Bacillus thuringiensis Toxins; Bacterial Proteins / genetics; China; Endotoxins / genetics; Female; Hemolysin Proteins / genetics; Insecticide Resistance / genetics; Larva / physiology; Moths / genetics; Toxicity Tests
TL;DR: The low frequency of resistance alleles found in this study and in the previous results from 2002 to 2005 suggest the frequency of Resistance alleles has remained low and that natural refugia resistance management strategy maybe effective for delaying resistance evolution in H. armigera to Bt cotton in northern China. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumours

VETERINARY AND COMPARATIVE ONCOLOGY, 7(2), 106–114.

By: K. Shiomitsu n, C. Johnson n, D. Malarkey*, A. Pruitt n & D. Thrall n

author keywords: canine; EGFR; nasal tumour; radiosensitivity; VEGF
MeSH headings : Animals; Dog Diseases / metabolism; Dog Diseases / pathology; Dog Diseases / radiotherapy; Dogs; ErbB Receptors / metabolism; Gene Expression Regulation, Neoplastic; Immunohistochemistry / veterinary; Neoplasms, Glandular and Epithelial / metabolism; Neoplasms, Glandular and Epithelial / pathology; Neoplasms, Glandular and Epithelial / radiotherapy; Neoplasms, Glandular and Epithelial / veterinary; Nose Neoplasms / radiotherapy; Nose Neoplasms / veterinary; Treatment Outcome; Vascular Endothelial Growth Factor A / metabolism
TL;DR: Findings indicate that EGFR and VEGF proteins were present in some malignant epithelial nasal tumours in the dogs, and therefore, it may be beneficial to treat canine patients with tumours that overexpress EG FR and V EGF with specific inhibitors in conjunction with radiation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Excited-State Energy Flow in Phenylene-Linked Multiporphyrin Arrays

JOURNAL OF PHYSICAL CHEMISTRY B, 113(23), 8011–8019.

By: H. Song  n, M. Taniguchi n , M. Speckbacher n, L. Yu n, D. Bocian  n, J. Lindsey n , D. Holten  n

TL;DR: Simulations of the energy-transfer properties of fictive dodecameric arrays based on the data reported herein show that nonadjacent transfer steps make a significant contribution to the observed performance of such larger molecular architectures and indicate that energy transfer betweenNonadjacent sites has important implications for the design of multichromophore arrays for molecular-photonic and solar-energy applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Estimates of natural selection due to protein tertiary structure inform the ancestry of biallelic loci

Gene, 441(1-2), 45–52.

By: S. Choi n, E. Stone n, H. Kishino * & J. Thorne n

MeSH headings : Evolution, Molecular; Gene Frequency; Humans; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Proteins / genetics; Selection, Genetic
TL;DR: This work focuses on 140 nonsynonymous single nucleotide polymorphisms of humans that are in proteins with known tertiary structures and finds that the technique for employing protein tertiary structure information yields some biologically plausible results but that it does not substantially improve the inference of ancestral human allele types. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Effect of nonsteroidal anti-inflammatory drugs with varied cyclooxygenase-2 selectivity on cyclooxygenase protein and prostanoid concentrations in pyloric and duodenal mucosa of dogs

American Journal of Veterinary Research, 70(10), 1243–1249.

By: J. Wooten n, A. Blikslager n , S. Marks n, J. Law n, E. Graeber n & B. Lascelles  n

Contributors: J. Wooten n, A. Blikslager n , S. Marks n, J. Law n, E. Graeber n & B. Lascelles  n

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Dogs; Drug Administration Schedule; Female; Gastric Mucosa / drug effects; Gastric Mucosa / metabolism; Gene Expression Regulation / drug effects; Male; Prostaglandin-Endoperoxide Synthases / metabolism; Prostaglandins / metabolism
TL;DR: It is suggested that, for these experimental conditions, there were no differences among the preferential and selective COX-2 inhibitors with regard to adverse effects on the gastric and duodenal portions of the gastrointestinal tract of dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum

American Journal of Veterinary Research, 70(8), 992–1000.

By: V. Cook n, C. Meyer n, N. Campbell n & A. Blikslager n 

Contributors: V. Cook n, C. Meyer n, N. Campbell n & A. Blikslager n 

MeSH headings : 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / therapeutic use; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Blotting, Western / veterinary; Clonixin / analogs & derivatives; Clonixin / therapeutic use; Cyclooxygenase 1 / metabolism; Cyclooxygenase 2 / metabolism; Eicosanoids / blood; Electrophoresis, Polyacrylamide Gel / veterinary; Horse Diseases / drug therapy; Horses; Ischemia / drug therapy; Ischemia / veterinary; Jejunal Diseases / drug therapy; Jejunal Diseases / veterinary; Sulfones / therapeutic use; Thromboxane B2 / blood
TL;DR: Firocoxib may be advantageous in horses recovering from ischemic intestinal injury, while providing effective analgesia in horses treated with flunixin meglumine and firo Coxib. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Dermal Permeation of Biocides and Aromatic Chemicals in Three Generic Formulations of Metalworking Fluids

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 72(13), 832–841.

By: V. Vijay n, E. White*, M. Kaminski *, J. Riviere n & R. Baynes n

MeSH headings : Animals; Complex Mixtures / chemistry; Disinfectants / chemistry; Disinfectants / pharmacokinetics; Hydrocarbons, Aromatic / chemistry; Hydrocarbons, Aromatic / pharmacokinetics; Metallurgy; Occupational Exposure; Permeability; Skin Absorption / drug effects; Swine
TL;DR: Data from this study show that permeation of chemicals is higher in a generic synthetic MWF when compared to a soluble oil MWF, which indicates that a solubleOil MWF may be safer than a syntheticMWF in regard to dermal permeations of chemicals to allow for an increased potential of systemic toxicity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia

JOURNAL OF NEURODEVELOPMENTAL DISORDERS, 1(4), 302–312.

By: S. Moy*, H. Ghashghaei *, R. Nonneman*, J. Weimer *, Y. Yokota*, D. Lee*, C. Lai *, D. Threadgill *, E. Anton*

author keywords: Grin1; Growth factor; NMDA receptor; Schizophrenia; Sociability; Social novelty
TL;DR: Findings provide evidence that social behavior is mediated by NRG1-ERBB signaling, which is implicated in genetic susceptibility for schizophrenia and has been implicated in asociality and altered social interaction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Conductive oxide thin films: Model systems for understanding and controlling surface plasmon resonance

Journal of Applied Physics, 106(2), 024903.

By: M. Losego n, A. Efremenko n, C. Rhodes n, M. Cerruti n, S. Franzen n  & J. Maria n

UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2009 journal article

Comparison of diffraction-enhanced computed tomography and monochromatic synchrotron radiation computed tomography of human trabecular bone

PHYSICS IN MEDICINE AND BIOLOGY, 54(20), 6123–6133.

By: D. Connor n, H. Hallen  n, D. Lalush n, D. Sumner * & Z. Zhong *

MeSH headings : Absorption; Bone and Bones / diagnostic imaging; Bone and Bones / pathology; Equipment Design; Humans; Normal Distribution; Radiographic Image Interpretation, Computer-Assisted / methods; Scattering, Radiation; Silicon; Synchrotrons; Tibia / diagnostic imaging; Tibia / pathology; Tomography, X-Ray Computed / methods; X-Rays
TL;DR: The apparent absorption DECT images have significantly higher spatial resolution and CNR than the corresponding SRCT images, and will prove to be a useful tool for imaging applications in which high contrast and high spatial resolution are required for both soft tissue features and bone. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Chlorin-Bacteriochlorin Energy-transfer Dyads as Prototypes for Near-infrared Molecular Imaging Probes: Controlling Charge-transfer and Fluorescence Properties in Polar Media

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 85(4), 909–920.

By: H. Kee*, J. Diers *, M. Ptaszek n, C. Muthiah n, D. Fan n, J. Lindsey n , D. Bocian *, D. Holten *

MeSH headings : Energy Transfer; Fluorescence; Molecular Probes; Oxidation-Reduction; Porphyrins / chemistry; Quantum Theory; Spectroscopy, Near-Infrared
TL;DR: Controlling the extent of excited‐state quenching in polar media will allow the favorable photophysical properties of the chlorin–bacteriochlorin dyads to be exploited in vivo and facilitate selective excitation/detection and multiprobe applications using both intensity‐ and lifetime‐imaging techniques. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Characterization of vitellin protein in the twospotted spider mite, Tetranychus urticae (Acari: Tetranychidae)

JOURNAL OF INSECT PHYSIOLOGY, 55(7), 655–661.

By: A. Cabrera n, K. Donohue n, S. Khalil  n, D. Sonenshine* & R. Roe n 

author keywords: Mite; Spider mite; Tick; American dog tick; Vitellogenin; Vitellin; Yolk protein; Reproduction; Egg
MeSH headings : Animals; Heme / metabolism; Isoelectric Point; Molecular Weight; Protein Stability; Tetranychidae / chemistry; Tetranychidae / metabolism; Ticks / chemistry; Ticks / metabolism; Vitellins / chemistry; Vitellins / metabolism
TL;DR: Spider mite vitellin weakly bound lipids and carbohydrates compared to the tick, and unlike D. variabilis, the spider mite egg yolk protein does not bind heme. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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