Works Published in 2020
Displaying works 81 - 100 of 114 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
The PDE4 inhibitor CHF6001 affects keratinocyte proliferation via cellular redox pathways
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 685.
author keywords: NOX; NF-kappa B; Cyclin D1; Skin; p21
MeSH headings : Aldehydes / metabolism; Cell Line; Cell Proliferation / drug effects; Cell Survival / drug effects; Cyclin D1 / metabolism; Humans; Keratinocytes / drug effects; Lipid Peroxidation / drug effects; NADPH Oxidases / metabolism; Oxidative Stress / drug effects; Phosphodiesterase 4 Inhibitors / pharmacology; Phosphodiesterase 4 Inhibitors / toxicity; Psoriasis / drug therapy; Sulfonamides / pharmacology; Sulfonamides / toxicity; Transcription Factor RelA / metabolism; para-Aminobenzoates / pharmacology; para-Aminobenzoates / toxicity
TL;DR:
CHF6001 has the potential to treat skin disorders associated with hyperproliferative keratinocytes, such as psoriasis by targeting oxidative stress, abnormal re-epithelization, and inflammation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020
2020 journal article
In Vitro Bioaccessibility of Carotenoids and Chlorophylls in a Diverse Collection of Spinach Accessions and Commercial Cultivars
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(11), 3495–3505.
author keywords: spinach; carotenoids; lutein; beta-carotene; chlorophyll; genotypes; bioaccessibility; in vitro digestion
MeSH headings : Carotenoids; Chlorophyll; Chlorophyll A; Spinacia oleracea / genetics; beta Carotene
TL;DR:
The results suggest that carotenoid and chlorophyll bioaccessible contents may vary based on spinach genotypes and may be stable across seasons.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020
2020 journal article
Isolation of Exopolysaccharide-Producing Yeast and Lactic Acid Bacteria from Quinoa (Chenopodium Quinoa) Sourdough Fermentation
FOODS, 9(3).
author keywords: lactic acid bacteria; pseudocereals; fermentation; quinoa; exopolysaccharides
TL;DR:
This study characterizes quinoa flour spontaneous fermentation with emphasis in the isolation of exopolysaccharide producer bacteria, which might be a potential candidate for quinoa sourdough production.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020
2020 journal article
Effect of edible plant materials on provitamin A stability and bioaccessibility from extruded whole pearl millet (P. typhoides) composite blends
LWT-FOOD SCIENCE AND TECHNOLOGY, 123.
author keywords: Pearl millet; African plants; Extrusion; Provitamin A; Bioaccessibility; Starch digestion
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 27, 2020
2020 article
The Colors of Health: Chemistry, Bioactivity, and Market Demand for Colorful Foods and Natural Food Sources of Colorants
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 145–182.
author keywords: anthocyanins; betalains; bioactivity; carotenoids; natural colors; phycocyanins
MeSH headings : Color; Food; Pigments, Biological / chemistry
TL;DR:
The color industry needs new sources of stable, functional, and safe natural food colorants, and new opportunities include sourcing new colors from microbial sources and via the use of genetic biotechnology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020
2020 article
Skin Health from the Inside Out
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 235–254.
author keywords: pollution; skin; diet; GI tract; inflammation; antioxidant; vitamins
MeSH headings : Antioxidants / metabolism; Humans; Reactive Oxygen Species / metabolism; Skin Physiological Phenomena
TL;DR:
This review discusses how topical application of antioxidants, including vitamins C and E, carotenoids, resveratrol, and pycnogenol, can be combined with dietary supplementation of these antioxidant compounds in addition to probiotics and essential minerals to protect against outdoor stressor-induced skin damage, including the damage associated with aging.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020
2020 journal article
Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery
ANTIOXIDANTS & REDOX SIGNALING, 33(3), 191–210.
author keywords: Alzheimer's disease; inflammation; multiple sclerosis; vascular dementia
MeSH headings : Animals; Biomarkers; Blood-Brain Barrier / metabolism; Brain / metabolism; Brain / pathology; Disease Susceptibility; Dysbiosis; Humans; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Nervous System Diseases / etiology; Nervous System Diseases / metabolism; Nervous System Diseases / pathology; Oxidative Stress; Peripheral Nerves / metabolism; Peripheral Nerves / pathology
TL;DR:
Reaching a definitive clinical/epidemiological appreciation of the etiopathogenic significance of the connection between peripheral and brain inflammation in neurologic disorders is pivotal since it could open novel therapeutic avenues for these diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020
2020 review
Celtic Provenance in Traditional Herbal Medicine of Medieval Wales and Classical Antiquity
[Review of ]. FRONTIERS IN PHARMACOLOGY, 11.
author keywords: medicinal plants; ethnopharmacology; ethnobotany; herbal texts; bioactive compounds
TL;DR:
This review provides initial evidence for traces of Celtic framework in the Welsh herbal tradition and warrants further investigations of bioactivity and clinical applications of the described plant leads.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020
2020 journal article
Venomics of the ectoparasitoid wasp Bracon nigricans
BMC GENOMICS, 21(1).
author keywords: Idiobiont parasitoids; Host-parasitoid interactions; Venom proteome; Venom transcriptome; Host regulation
MeSH headings : Animals; Host-Parasite Interactions; Insect Proteins / genetics; Insect Proteins / metabolism; Proteomics; Transcriptome / genetics; Wasp Venoms / genetics; Wasp Venoms / metabolism; Wasps / genetics; Wasps / metabolism
TL;DR:
A combined transcriptomic and proteomic study of the venom of the generalist idiobiont wasp Bracon nigricans, an ectophagous larval parasitoid of different lepidopteran species, provides the foundation on which to develop a functional model of host regulation, based both on physiological and molecular data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
'Liz' and 'Rocco' Strawberries
HORTSCIENCE, 55(4), 597–600.
author keywords: Fragaria Xananassa; fresh market; June-bearing; short-day
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Consumer Acceptance and Willingness to Pay for Instant Cereal Products With Food-to-Food Fortification in Eldoret, Kenya
FOOD AND NUTRITION BULLETIN, 41(2), 224–243.
author keywords: consumers; maize; sorghum; instant; Africa; fortified flour; cereals
MeSH headings : Adult; Consumer Behavior; Female; Food Handling; Food, Fortified / economics; Humans; Kenya; Male; Socioeconomic Factors; Zea mays
TL;DR:
There is a potential market for improved cereal products in Kenya, but more for uji than for ugali, especially with instant, mixed, and whole flour.
(via Semantic Scholar)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder
FASEB JOURNAL, 34(5), 6521–6538.
author keywords: 4-hydroxynonenal; fission; fusion; mitophagy; nuclear factor erythroid 2-related factor 2
MeSH headings : Adolescent; Adult; Autism Spectrum Disorder / metabolism; Autism Spectrum Disorder / pathology; Case-Control Studies; Child; Energy Metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; Humans; Male; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Dynamics; Mitochondrial Proteins / metabolism; Oxidative Stress; Young Adult
TL;DR:
It is suggested that many of the changes observed in mitochondria could represent compensatory mechanisms by which ASD cells try to adapt to altered energy demand, possibly resulting from a chronic oxinflammatory status.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020
2020 journal article
LC-MS characterization of bioactive metabolites from two Yemeni Aloe spp. with antioxidant and antidiabetic properties
ARABIAN JOURNAL OF CHEMISTRY, 13(4), 5040–5049.
Contributors: T. Aldayel *, M. Grace n , M. Lila n , M. Yahya *, U. Omar * & G. Alshammary*
author keywords: LC-ESI-IT-TOF; Aloe; Phenolics; alpha-Glucosidase inhibition; Antioxidant activity
TL;DR:
Findings highlight the phytochemical profile, antioxidant and potential antidiabetic activity of the Yemeni Aloe species and draw attention to their potential application in food, medicine and cosmetic products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 20, 2020
2020 journal article
A Novel Botanical Combination Attenuates Light-Induced Retinal Damage through Antioxidant and Prosurvival Mechanisms
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2020.
MeSH headings : Animals; Antioxidants / pharmacology; Antioxidants / therapeutic use; Disease Models, Animal; Humans; Male; Rats; Rats, Sprague-Dawley; Retina / pathology; Retinal Diseases / drug therapy
TL;DR:
Investigation of the effects of a novel combination of lutein ester, zeaxanthin, chrysanthemum, goji berry, and black currant extracts against retinal damage found the botanical combination can alleviate light-induced retina damage, potentially through antioxidant and prosurvival mechanisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 14, 2020
2020 journal article
Diversity in Metabolites and Fruit Quality Traits in Blueberry Enables Ploidy and Species Differentiation and Establishes a Strategy for Future Genetic Studies
Frontiers in Plant Science, 11.
Contributors: M. Mengist n, M. Grace n , J. Xiong n , C. Kay n, N. Bassil *, K. Hummer *, M. Ferruzzi n, M. Lila n, M. Iorizzo n
author keywords: blueberry; health promoting phytochemicals; fruit size; ploidy; fruit quality; flavonoid pathway
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: April 11, 2020
2020 journal article
Lily steroidal glycoalkaloid promotes early inflammatory resolution in wounded human fibroblasts
Journal of Ethnopharmacology.
author keywords: Steroidal glycoalkaloid; Lilium longiflorum Thunb.; Scratch migration assay; Gene expression; Easter lily; Human dermal fibroblast cells
MeSH headings : Alkaloids / isolation & purification; Alkaloids / pharmacology; Cell Movement / drug effects; Cells, Cultured; Chromatography, Liquid; Fibroblasts / drug effects; Fibroblasts / pathology; Flowers; Gene Expression Regulation / drug effects; Glycosides / isolation & purification; Glycosides / pharmacology; Humans; Inflammation / drug therapy; Inflammation / pathology; Lilium / chemistry; Plant Roots; Wound Healing / drug effects
TL;DR:
It is demonstrated that a glycoalkaloid present in lilies promoted fibroblast migration in vitro and affected inflammatory, remodeling and growth factor gene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: April 11, 2020
2020 journal article
Impact of sun-simulated white light and varied blue:red spectrums on the growth, morphology, development, and phytochemical content of green-and red-leaf lettuce at different growth stages
SCIENTIA HORTICULTURAE, 264.
author keywords: Light-emitting diode; Plant factory; Indoor farming; Bolting; Solar spectrum; Transplant; Baby-leaf lettuce; Head lettuce
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer's disease
GEROSCIENCE, 42(1), 159–167.
author keywords: Late-onset Alzheimer's disease; Mild cognitive impairment; Mixed dementia; Blood-based biomarkers; BACE1
MeSH headings : Alzheimer Disease / diagnosis; Amyloid Precursor Protein Secretases; Amyloid beta-Peptides; Aspartic Acid Endopeptidases; Biomarkers; Humans
TL;DR:
The data suggest that increased BACE1 activity in serum may represent a potential biomarker for LOAD, and additional studies are needed to confirm the usefulness of Bace1, alone or in combination with other markers, in discriminating patients and predicting LOAD onset and progression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 16, 2020
2020 journal article
Identification of an SCPL Gene Controlling Anthocyanin Acylation in Carrot (Daucus carota L.) Root
FRONTIERS IN PLANT SCIENCE, 10.
author keywords: Daucus carota L; anthocyanins; acyltransferase; fine mapping; transcriptome; candidate genes
TL;DR:
Strong linkage-mapping and functional evidences are provided for the candidacy of DcSCPL1 as a primary regulator of anthocyanin acylation in carrot storage root.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 10, 2020
2020 journal article
Exploring the Anti-Acne Potential of Impepho [Helichrysum odoratissimum (L.) Sweet] to Combat Cutibacterium acnes Virulence
FRONTIERS IN PHARMACOLOGY, 10.
author keywords: Helichrysum odoratissimum (L; ) Sweet; Cutibacterium acnes; anti-acne; antibiofilm; pathogenesis
TL;DR:
This study provides scientific validation for the traditional use of H. odoratissimum as an ointment for pimples, not only due to its ability to control C. acnes proliferation but also because of its inhibitory activity on various targets associated with bacterial virulence leading to acne progression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 10, 2020
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