Works Published in 2010

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Displaying works 81 - 100 of 128 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Evaluation of peptide- and recombinant protein-based assays for detection of anti-Ehrlichia ewingii antibodies in experimentally and naturally infected dogs

American Journal of Veterinary Research, 71(10), 1195–1200.

By: T. O'Connor*, J. Saucier, D. Daniluk, B. Stillman, R. Krah, Y. Rikihisa, Q. Xiong, M. Yabsley ...

MeSH headings : Animals; Antibodies, Bacterial / blood; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Ehrlichia / immunology; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; False Positive Reactions; Immunoassay / methods; Immunoassay / veterinary; Missouri / epidemiology; Peptides; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Recombinant Proteins
TL;DR: The EESP and EETp28 ELISAs were suitable for specifically detecting anti-E ewingii antibodies in experimentally and naturally infected dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Correcting the bias of empirical frequency parameter estimators in codon models

PLoS One, 5(7).

By: S. Pond, W. Delport, S. Muse & K. Scheffler

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Clonal evaluation for fusiform rust disease resistance: effects of pathogen virulence and disease escape

CANADIAN JOURNAL OF FOREST RESEARCH-REVUE CANADIENNE DE RECHERCHE FORESTIERE, 40(6), 1042–1050.

By: G. Kayihan n, C. Nelson n, D. Huber n, H. Amerson n, T. White n & J. Davis n

TL;DR: The precision of phenotypic classification for fusiform rust resistance of Pinus taeda L. taeda in a clonally propagated population segregating for the pathotype-specific resistance gene Fr1 was evaluated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Adaptation in a Mouse Colony Monoassociated with Escherichia coli K-12 for More than 1,000 Days

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(14), 4655–4663.

By: S. Lee*, A. Wyse*, A. Lesher*, M. Everett*, L. Lou*, Z. Holzknecht*, J. Whitesides n, P. Spears n ...

MeSH headings : Animals; Escherichia coli K12 / genetics; Escherichia coli K12 / growth & development; Gastrointestinal Tract / microbiology; Longitudinal Studies; Mice; Restriction Mapping
TL;DR: The results suggest that monoassociated mice might be used as a tool for characterizing niches occupied by the intestinal flora and potentially as a method of targeting the evolution of bacteria for applications in biotechnology. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 review

The potential for caspases in drug discovery

[Review of ]. Current Opinion in Drug Discovery & Development, 13(5), 568–576.

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Structural studies of sparsely substituted synthetic chlorins and phorbines establish benchmarks for changes in the ligand core and framework of chlorophyll macrocycles

JOURNAL OF MOLECULAR STRUCTURE, 979(1-3), 27–45.

author keywords: Chlorophyll; Chlorin; Phorbine; Isocyclic ring; Chiral volume; Aromaticity
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy

FASEB JOURNAL, 24(9), 3160–3170.

By: P. Mroz*, Y. Huang*, A. Szokalska*, T. Zhiyentayev*, S. Janjua*, A. Nifli*, M. Sherwood*, C. Ruzie n ...

author keywords: multidrug resistance; melanosomes; electron microscopy
MeSH headings : Animals; Cell Line, Tumor; Male; Melanoma / drug therapy; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Molecular Structure; Photochemotherapy / methods; Porphyrins / chemical synthesis; Porphyrins / chemistry; Porphyrins / therapeutic use
TL;DR: The extent of melanin contribution to melanoma resistance to PDT was investigated in a set of melanoma cell lines that markedly differ in the levels of pigmentation;3 new bacteriochlorins successfully overcame the resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Severe Hepatitis Associated with Acute Ehrlichia canis Infection in a Dog

Journal of Veterinary Internal Medicine, 24(3), 633–638.

By: M. Mylonakis*, M. Kritsepi-Konstantinou*, J. Dumler*, P. Diniz*, M. Day*, V. Siarkou*, E. Breitschwerdt n, V. Psychas* ...

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dogs; Doxycycline / therapeutic use; Ehrlichia canis; Ehrlichiosis / complications; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Hepatitis, Animal / etiology; Hepatitis, Animal / microbiology; Male
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Probing the Rate of Hole Transfer in Oxidized Porphyrin Dyads Using Thallium Hyperfine Clocks

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(34), 12121–12132.

MeSH headings : Molecular Conformation; Organometallic Compounds / chemical synthesis; Organometallic Compounds / chemistry; Oxidation-Reduction; Photochemistry; Porphyrins / chemistry; Stereoisomerism; Thallium / chemistry
TL;DR: Variable-temperature EPR studies further demonstrate that the hole/electron-transfer process is at best weakly activated at room temperature and somewhat below, and provide the physical basis for the rational design of multicomponent architectures for efficient hole/Electron transfer. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Interferon Regulatory Factor 3 Attenuates Reovirus Myocarditis and Contributes to Viral Clearance

JOURNAL OF VIROLOGY, 84(14), 6900–6908.

MeSH headings : Animals; Animals, Newborn; Cells, Cultured; Humans; Immunity; Interferon Regulatory Factor-3 / genetics; Interferon Regulatory Factor-3 / metabolism; Interferon-beta / genetics; Interferon-beta / metabolism; Liver / pathology; Liver / virology; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocarditis / immunology; Myocarditis / pathology; Myocarditis / virology; Myocytes, Cardiac / pathology; Myocytes, Cardiac / virology; Reoviridae / metabolism; Reoviridae / pathogenicity; Reoviridae Infections / immunology; Reoviridae Infections / pathology; Reoviridae Infections / virology; Spleen / pathology; Spleen / virology; Survival Rate; Tissue Distribution
TL;DR: Cellular and humoral immune responses were equivalent in wild-type and IRF-3−/− animals, suggesting that IRf-3 functions independently of the adaptive immune response to enhance reovirus clearance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Insect response to alphavirus infection-Establishment of alphavirus persistence in insect cells involves inhibition of viral polyprotein cleavage

VIRUS RESEARCH, 150(1-2), 73–84.

author keywords: Arbovirus; Sindbis; Insect cells; Microarray; Persistent infection
MeSH headings : Alphavirus / pathogenicity; Alphavirus / physiology; Animals; Cell Line; Drosophila; Polyproteins / metabolism; Viral Proteins / metabolism; Virus Replication
TL;DR: It is proposed that inefficient cleavage of the polyprotein may lead to reduced levels of virus seen as persistence is established, and the up-regulation of a wide-spectrum protease inhibitor, Thiol-ester containing Protein (TEP) II is confirmed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

In vivo depletion of CD4(+)CD25(hi) regulatory T cells is associated with improved antiviral responses in cats chronically infected with feline immunodeficiency virus

VIROLOGY, 403(2), 163–172.

author keywords: Feline immunodeficiency virus; HIV-1; Lentivirus; Regulatory T cell; Immunosuppression; Monoclonal antibody
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Viral / blood; CD4 Antigens / analysis; Cat Diseases / immunology; Cat Diseases / virology; Cats; Female; Immunodeficiency Virus, Feline / immunology; Interleukin-2 Receptor alpha Subunit / analysis; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Lymphocyte Depletion; T-Lymphocytes, Regulatory / chemistry; T-Lymphocytes, Regulatory / immunology
TL;DR: It is proposed that short-term in vivo Treg cell depletion during chronic HIV-1 infection could provide a window of opportunity for therapeutic vaccination in individuals with controlled viral replication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

In Vitro Photodynamic Therapy and Quantitative Structure-Activity Relationship Studies with Stable Synthetic Near-Infrared-Absorbing Bacteriochlorin Photosensitizers

JOURNAL OF MEDICINAL CHEMISTRY, 53(10), 4018–4027.

By: Y. Huang, P. Mroz*, T. Zhiyentayev, S. Sharma*, T. Balasubramanian, C. Ruzie*, M. Krayer*, D. Fan* ...

MeSH headings : Cell Death / drug effects; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Infrared Rays; Photochemotherapy; Photosensitizing Agents / chemistry; Photosensitizing Agents / metabolism; Photosensitizing Agents / pharmacology; Porphyrins / chemistry; Porphyrins / metabolism; Porphyrins / pharmacology; Quantitative Structure-Activity Relationship; Quantum Theory
TL;DR: Testing of 12 new stable synthetic bacteriochlorins for PDT activity described, which possess a variety of peripheral substituents and are very potent in killing cancer cells in vitro after illumination, gives them great potential as photosensitizers for treatment of cancer. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Evolutionary history of two endemic Appalachian conifers revealed using microsatellite markers

CONSERVATION GENETICS, 11(4), 1499–1513.

By: K. Potter n, J. Frampton n, S. Josserand* & C. Nelson*

author keywords: Biogeography; Pleistocene; Migration; Population genetics; Microsatellite markers; Abies
TL;DR: Little genetic differentiation is found among Fraser fir and intermediate fir, suggesting that Fraser fir might best be classified as a variety of balsam fir, and the results appear to reject the hypothesis that intermediate fir was of hybrid origin between two comparatively distantly related species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Codontest: modeling amino acid substitution preferences in coding sequences

PLoS Computational Biology, 6(8).

By: W. Delport, K. Scheffler, G. Botha, M. Gravenor, S. Muse & S. Pond

Source: NC State University Libraries
Added: August 6, 2018

2010 review

Towards a Systems Approach for Lignin Biosynthesis in Populus trichocarpa: Transcript Abundance and Specificity of the Monolignol Biosynthetic Genes

[Review of ]. PLANT AND CELL PHYSIOLOGY, 51(1), 144–163.

author keywords: Lignin systems biology; Monolignol biosynthesis; Populus trichocarpa; Promoter motifs; Transcript abundance; Xylem-specific expression
MeSH headings : Amino Acid Motifs / genetics; Biosynthetic Pathways / genetics; Enzymes / biosynthesis; Enzymes / genetics; Gene Expression Regulation, Enzymologic / physiology; Gene Expression Regulation, Plant / physiology; Genome, Plant / genetics; Lignin / biosynthesis; Lignin / genetics; Phloem / enzymology; Phloem / genetics; Plant Shoots / enzymology; Plant Shoots / genetics; Populus / genetics; Populus / metabolism; Promoter Regions, Genetic / genetics; RNA, Messenger / analysis; RNA, Messenger / genetics; RNA, Messenger / metabolism; RNA, Plant / analysis; RNA, Plant / genetics; RNA, Plant / metabolism; Transcription, Genetic / physiology; Xylem / enzymology; Xylem / genetics
TL;DR: The identified 23 genes that most probably encode monolignol biosynthesis enzymes during wood formation are identified and evidence suggesting functional redundancy at the transcript level for phenylalanine ammonia-lyase and cinnamate 4-hydroxylase is found. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

The use of pooled vs serial urine samples to measure urine protein:creatinine ratios

VETERINARY CLINICAL PATHOLOGY, 39(1), 53–56.

author keywords: Dog; proteinuria; protein:creatinine ratio; UPC
MeSH headings : Animals; Creatinine / urine; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Kidney Failure, Chronic / urine; Kidney Failure, Chronic / veterinary; Proteinuria / veterinary; Specimen Handling
TL;DR: Measuring the UPC ratio in a pooled sample containing equal volumes of several different urine specimens from the same dog provides a reliable and cost-effective alternative to assessing multiple UPC ratios on several specimens fromThe same dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Identification and Characterization of Two Bordetella avium Gene Products Required for Hemagglutination

INFECTION AND IMMUNITY, 78(6), 2370–2376.

By: L. Temple*, D. Miyamoto*, M. Mehta*, C. Capitini*, S. Von Stetina*, H. Barnes n, V. Christensen n, J. Horton n, P. Spears n, P. Orndorff n

MeSH headings : Animals; Antibodies, Bacterial / immunology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bordetella avium / pathogenicity; Cell Adhesion; Cells, Cultured; DNA Transposable Elements; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Epithelial Cells / microbiology; Erythrocytes / microbiology; Gene Order; Guinea Pigs; Hemagglutination; Hemagglutinins / genetics; Hemagglutinins / metabolism; Molecular Sequence Data; Mutagenesis, Insertional; Poultry Diseases / microbiology; Sequence Analysis, DNA; Sequence Deletion; Trachea / microbiology; Turkeys
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Evaluation of Brain Tissue or Cerebrospinal Fluid with Broadly Reactive Polymerase Chain Reaction for Ehrlichia, Anaplasma, Spotted Fever Group Rickettsia, Bartonella, and Borrelia Species in Canine Neurological Diseases (109 Cases)

Journal of Veterinary Internal Medicine, 24(2), 372–378.

By: R. Barber*, Q. Li*, P. Diniz*, B. Porter*, E. Breitschwerdt n, M. Claiborne*, A. Birkenheuer n, J. Levine* ...

author keywords: Central nervous system (CNS); Inflammation; Meningoencephalomyelitis; Vector-borne microorganisms
MeSH headings : Animals; Brain / microbiology; DNA, Bacterial / classification; DNA, Bacterial / isolation & purification; Dog Diseases / cerebrospinal fluid; Dog Diseases / microbiology; Dogs; Female; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacterial Infections / cerebrospinal fluid; Gram-Negative Bacterial Infections / microbiology; Gram-Negative Bacterial Infections / veterinary; Male; Meningoencephalitis / microbiology; Meningoencephalitis / veterinary; Polymerase Chain Reaction / veterinary
TL;DR: The results of this investigation suggest that microorganisms in the genera Ehrlichia, Anaplasma, Rickettsia, Bartonella, and Borrelia are unlikely to be directly associated with canine MEM in the geographic regions evaluated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Detection of alternative splice variants at the proteome level in Aspergillus flavus

Journal of Proteome Research, 9(3), 1209–1217.

By: K. Chang, D. Georgianna, S. Heber, G. Payne & D. Muddiman

Source: NC State University Libraries
Added: August 6, 2018

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