Works Published in 2021

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Displaying works 1 - 20 of 80 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

A polyketide synthase gene cluster required for pathogenicity of Pseudocercospora fijiensis on banana

PLOS ONE, 16(10).

By: E. Thomas n, R. Noar n & M. Daub n

MeSH headings : Ascomycota / genetics; Ascomycota / pathogenicity; Fungal Proteins / genetics; Mycoses / microbiology; Plant Diseases / microbiology; Polyketide Synthases / genetics
TL;DR: An important role for the PKS10-2 polyketide pathway in pathogenicity of Pseudocercospora fijiensis is supported, and a possible role for this pathway in disease development by other PseudOCercOSpora species is suggested. (via Semantic Scholar)
Source: Web Of Science
Added: February 28, 2022

2021 journal article

Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species

PLOS COMPUTATIONAL BIOLOGY, 17(9).

MeSH headings : Animals; Biomarkers, Tumor / genetics; Bone Neoplasms / genetics; Bone Neoplasms / veterinary; Computational Biology; Dog Diseases / classification; Dog Diseases / genetics; Dogs; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Lung Neoplasms / genetics; Lung Neoplasms / veterinary; Lymphoma, B-Cell / genetics; Lymphoma, B-Cell / veterinary; Lymphoma, T-Cell / genetics; Lymphoma, T-Cell / veterinary; Melanoma / genetics; Melanoma / veterinary; Molecular Sequence Annotation; Molecular Targeted Therapy; Neoplasms / classification; Neoplasms / genetics; Neoplasms / veterinary; Oncogenes; Osteosarcoma / genetics; Osteosarcoma / veterinary; Species Specificity; Translational Research, Biomedical
TL;DR: An experimental-bioinformatic protocol is developed that analyzes canine transcriptomics data in the context of existing human data to evaluate comparative relevance of canine to human cancer, and demonstrates transferability of classification models from canines to humans. (via Semantic Scholar)
Source: Web Of Science
Added: February 21, 2022

2021 journal article

Research Design, Protocol, and Participant Characteristics of COLEAFS: A Cluster Randomized Controlled Trial of a Childcare Garden Intervention

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(24).

By: N. Cosco n, N. Wells*, M. Monsur*, L. Goodell n, D. Zhang n, T. Xu*, D. Hales*, R. Moore n

author keywords: children; childcare; gardening; randomized controlled trial; healthy eating; physical activity
MeSH headings : Child; Child Care; Child, Preschool; Fruit; Gardening; Gardens; Health Promotion; Humans; Research Design; Vegetables
TL;DR: By employing an RCT to examine the effect of a garden intervention on diet and physical activity among young children attending childcare centers within low-income communities, this study offers compelling research design and methods, addresses a critical gap in the empirical literature, and is a step toward evidence-based regulations to promote early childhood healthy habits. (via Semantic Scholar)
Source: Web Of Science
Added: January 18, 2022

2021 article

Comparative Assessment of Pesticide Exposures in Domestic Dogs and Their Owners Using Silicone Passive Samplers and Biomonitoring

Wise, C. F., Hammel, S. C., Herkert, N. J., Ospina, M., Calafat, A. M., Breen, M., & Stapleton, H. M. (2021, December 29). ENVIRONMENTAL SCIENCE & TECHNOLOGY.

author keywords: exposure; wristband; silicone; biomonitoring; pesticide; dog
MeSH headings : Animals; Biological Monitoring; Chlorpyrifos; Dogs; Environmental Exposure / analysis; Environmental Monitoring; Humans; Pesticides / analysis; Silicones
TL;DR: It is suggested that people and their dogs have similar pesticide exposures in a home environment as well as targeted gas chromatography-mass spectrometry analyses suggest. (via Semantic Scholar)
Source: Web Of Science
Added: January 18, 2022

2021 journal article

Quantitative Trait Locus Mapping for Common Scab Resistance in a Tetraploid Potato Full-Sib Population

PLANT DISEASE, 105(10), 3048–3054.

By: G. Pereira*, M. Mollinari n, X. Qu*, C. Thill*, Z. Zeng n, K. Haynes*, G. Yencho n

author keywords: disease resistance; polyploid QTL model; single-nucleotide polymorphism; Solanum tuberosum; Streptomyces spp
MeSH headings : Chromosome Mapping; Plant Tubers / genetics; Quantitative Trait Loci / genetics; Solanum tuberosum / genetics; Tetraploidy
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: January 18, 2022

2021 journal article

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

NUCLEIC ACIDS RESEARCH, 49(22), 13000–13018.

By: P. Kaur n, R. Barnes*, H. Pan n, A. Detwiler*, M. Liu n, C. Mahn n, J. Hall n, Z. Messenger n ...

MeSH headings : Animals; DNA / chemistry; DNA / genetics; DNA / metabolism; HeLa Cells; Humans; Mice, Inbred C57BL; Microscopy, Atomic Force; Nucleic Acid Conformation; Protein Binding; Shelterin Complex / genetics; Shelterin Complex / metabolism; Telomere / genetics; Telomere / metabolism; Telomere-Binding Proteins / genetics; Telomere-Binding Proteins / metabolism; Telomeric Repeat Binding Protein 2 / genetics; Telomeric Repeat Binding Protein 2 / metabolism
TL;DR: A molecular model in which TIN2 functions as an architectural protein to promote TRF2-mediated trans and cis higher-order nucleic acid structures at telomeres is proposed. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: January 18, 2022

2021 journal article

Epistasis for head morphology in Drosophila melanogaster

G3-GENES GENOMES GENETICS, 11(10).

By: E. Ozsoy*, M. Yilmaz*, B. Patlar*, G. Emecen*, E. Durmaz*, M. Magwire*, S. Zhou*, W. Huang*, R. Anholt n, T. Mackay n

author keywords: Drosophila Genetic Reference Panel; genome-wide association analyses; modifier loci; genetic interaction network
MeSH headings : Alleles; Animals; Chromosome Mapping; Drosophila melanogaster / genetics; Epistasis, Genetic; Genome-Wide Association Study
TL;DR: The Drosophila melanogaster Genetic Reference Panel of sequenced inbred lines is used to evaluate the magnitude of naturally occurring epistasis modifying the effects of mutations in jing and inv, two transcription factors that have subtle quantitative effects on head morphology as homozygotes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: January 10, 2022

2021 article

Epigenetic modification associated with climate regulates betulin biosynthesis in birch

Wang, J., Chen, B., Ali, S., Zhang, T., Wang, Y., Zhang, H., … Zhang, Q. (2021, December 4). JOURNAL OF FORESTRY RESEARCH.

By: J. Wang*, B. Chen*, S. Ali*, T. Zhang*, Y. Wang*, H. Zhang*, L. Wang*, Y. Zhang* ...

author keywords: Epigenetics; DNA methylation; Betulin; bHLH9 transcription factor; Hormesis; Climate change; Secondary metabolite
TL;DR: The role of environmental signals to induce epigenetic changes that result in betulin production is highlighted, possibly helping to develop resilient plants to combat ongoing climate change and enhance secondary metabolite production. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
Source: Web Of Science
Added: December 13, 2021

2021 article

Toward Sustainable Crop Protection: Aqueous Dispersions of Biodegradable Particles with Tunable Release and Rainfastness

Pirzada, T., Sohail, M., Tripathi, A., Farias, B. V., Mathew, R., Li, C., … Khan, S. A. (2021, November 27). ADVANCED FUNCTIONAL MATERIALS.

By: T. Pirzada n, M. Sohail n, A. Tripathi n, B. Farias n, R. Mathew n, C. Li n, C. Opperman n, S. Khan n

author keywords: cellulose ester dispersions; controlled release formulations; crop protection; fluopyram; rainfastness; solvent displacement; sustainable agriculture
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
Source: Web Of Science
Added: December 6, 2021

2021 article

BEL1-like Homeodomain Protein BLH6a Is a Negative Regulator of CAld5H2 in Sinapyl Alcohol Monolignol Biosynthesis in Poplar (vol 12,& nbsp;695223, 2021)

Wang, Q., Dai, X., Pang, H., Cheng, Y., Huang, X., Li, H., … Li, Q. (2021, September 9). BEL1-like Homeodomain Protein BLH6a Is a Negative Regulator of CAld5H2 in Sinapyl Alcohol Monolignol Biosynthesis in Poplar (vol 12,& nbsp;695223, 2021). FRONTIERS IN PLANT SCIENCE, Vol. 12.

By: Q. Wang*, X. Dai*, H. Pang*, Y. Cheng*, X. Huang*, H. Li*, X. Yan*, F. Lu* ...

author keywords: lignin; BEL1-like homeodomain protein; transcription factor; yeast one hybrid
TL;DR: This research presents a novel probabilistic procedure that allows for direct measurement of the response of the immune system to earthquake-triggered landsliding. (via Semantic Scholar)
Source: Web Of Science
Added: November 29, 2021

2021 article

Bartonella spp. seroepidemiology and associations with clinicopathologic findings in dogs in the United States

Lashnits, E., Thatcher, B., Carruth, A., Mestek, A., Buch, J., Beall, M., … Breitschwerdt, E. B. (2021, November 17). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 11.

By: E. Lashnits n, B. Thatcher*, A. Carruth*, A. Mestek*, J. Buch*, M. Beall*, P. Neupane n, R. Chandrashekar*, E. Breitschwerdt n

author keywords: bartonellosis; canine; seroreactivity; vector-borne; zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dogs; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Demographic and geographic findings for Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: November 29, 2021

2021 journal article

Phase I/II Trial of Vemurafenib in Dogs with Naturally Occurring, BRAF-mutated Urothelial Carcinoma

MOLECULAR CANCER THERAPEUTICS, 20(11), 2177–2188.

By: P. Rossman*, T. Zabka, A. Ruple*, D. Tuerck*, J. Ramos-Vara*, L. Liu, R. Mohallem*, M. Merchant ...

MeSH headings : Adolescent; Animals; Carcinoma, Transitional Cell / drug therapy; Carcinoma, Transitional Cell / pathology; Child; Disease Models, Animal; Dogs; Humans; Mutation; Proto-Oncogene Proteins B-raf / drug effects; Vemurafenib / pharmacology; Vemurafenib / therapeutic use
TL;DR: The safety, antitumor activity, and cutaneous pharmacodynamic effects of vemurafenib, and the development of drug resistance in dogs closely mimic those reported in humans, which suggests BRAF-mutated canine InvUC offers an important complementary animal model to improve BRAf-targeted therapies in humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 23, 2021

2021 journal article

Development of a Multiplex Droplet Digital PCR Assay for the Detection of Babesia, Bartonella, and Borrelia Species

PATHOGENS, 10(11).

author keywords: Babesia; Bartonella; Borrelia; Cytauxzoon; Piroplasma; Theileria; clinical diagnostics; molecular detection; digital droplet PCR; digital PCR
TL;DR: The ddPCR assay facilitated the simultaneous detection of co-infections with two and three vector-borne pathogens comprising four different genera (Babesia, Bartonella, Borrelia, and Theileria) from clinical and other sample sources. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 12, 2021

2021 journal article

Enzyme Complexes of Ptr4CL and PtrHCT Modulate Co-enzyme A Ligation of Hydroxycinnamic Acids for Monolignol Biosynthesis in Populus trichocarpa

FRONTIERS IN PLANT SCIENCE, 12.

By: C. Lin n, Y. Sun*, J. Song n, H. Chen n, R. Shi n, C. Yang n, J. Liu n, S. Tunlaya-Anukit n ...

author keywords: protein interaction; monolignol biosynthesis; wood formation; Populus trichocarpa; BiFC; metabolic flux
TL;DR: It is proposed that Ptr4CL/PtrHCT complexes modulate the metabolic flux of CoA ligation for monolignol biosynthesis during wood formation in P. trichocarpa. (via Semantic Scholar)
Source: Web Of Science
Added: November 8, 2021

2021 journal article

A New Type of Satellite Associated with Cassava Mosaic Begomoviruses

JOURNAL OF VIROLOGY, 95(21).

By: C. Aimone n, L. De Leon, M. Dallas n, J. Ndunguru, J. Ascencio-Ibanez n & L. Hanley-Bowdoin n

author keywords: Arabidopsis; begomovirus; cassava mosaic disease; SEGS
MeSH headings : Begomovirus / classification; Begomovirus / genetics; Begomovirus / isolation & purification; Begomovirus / pathogenicity; DNA, Viral / genetics; Genome, Viral; Manihot / virology; Mutation; Phylogeny; Plant Diseases / virology; Recombination, Genetic; Satellite Viruses / classification; Satellite Viruses / genetics; Satellite Viruses / isolation & purification; Satellite Viruses / pathogenicity; Tobacco / virology
TL;DR: SEGS-2, which was originally isolated from cassava crops displaying severe and atypical CMD symptoms in Tanzanian fields, is a novel begomovirus satellite that can compromise the development of durable CMD resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 1, 2021

2021 journal article

A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants

CELL HOST & MICROBE, 29(9), 1393-+.

By: Y. Wang*, Q. Gong*, Y. Wu*, F. Huang*, A. Ismayil*, D. Zhang*, H. Li n, H. Gu* ...

MeSH headings : Argonaute Proteins / genetics; Argonaute Proteins / metabolism; Calcium / metabolism; Calcium Signaling / genetics; Calmodulin / metabolism; Cucumovirus / pathogenicity; Endonucleases / metabolism; Geminiviridae / pathogenicity; MicroRNAs / metabolism; Plant Diseases / prevention & control; Plant Diseases / virology; Plants; Potyviridae / pathogenicity; RNA Interference / physiology; RNA, Small Interfering / genetics; RNA-Dependent RNA Polymerase / metabolism; Ribonuclease III / genetics; Ribonuclease III / metabolism; Tobacco / genetics; Tobacco / virology; Transcription Factors / metabolism
TL;DR: It is shown that wounding to Nicotiana benthamiana cells during virus intrusion activates RNAi-related gene expression through calcium signaling, linking Ca2+ signaling to RNAi and revealing versatility of host antiviral defense and viral counter-defense. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2021

2021 journal article

Molecular and Metabolic Insights into Anthocyanin Biosynthesis for Leaf Color Change in Chokecherry (Padus virginiana)

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(19).

By: X. Li*, Y. Li*, M. Zhao*, Y. Hu*, F. Meng*, X. Song*, M. Tigabu*, V. Chiang n ...

author keywords: Padus virginiana; leaf color; anthocyanin biosynthesis; transcriptomics; metabolomic
MeSH headings : Anthocyanins / biosynthesis; Biosynthetic Pathways; Chlorophyll / biosynthesis; Color; Computational Biology / methods; Gene Expression Profiling; Gene Expression Regulation, Plant; Metabolome; Metabolomics / methods; Pigmentation / genetics; Plant Leaves / genetics; Plant Leaves / metabolism; Prunus / physiology; Transcriptome
TL;DR: In PRL, the expression of the genes encoding for UGFT and BZ1 enzymes was substantially higher than in leaves of other colors and may be related with the purple-red color change, which may facilitate genetic modification or selection for further improvement in ornamental qualities of P. virginiana. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: October 26, 2021

2021 article

Single-cell RNA sequencing reveals a high-resolution cell atlas of xylem in Populus

Li, H., Dai, X., Huang, X., Xu, M., Wang, Q., Yan, X., … Li, Q. (2021, October 4). JOURNAL OF INTEGRATIVE PLANT BIOLOGY.

author keywords: differentiating trajectory; differentiating xylem; marker genes; Populus alba x Populus glandulosa; single-cell RNA-seq; wood formation
MeSH headings : Cell Differentiation; Cell Wall / metabolism; Gene Expression Profiling; Genome, Plant; Populus / cytology; Populus / genetics; Populus / metabolism; Sequence Analysis, RNA; Single-Cell Analysis; Xylem / cytology
TL;DR: This study generates a high resolution expression atlas of wood formation at the single cell level and provides valuable information on wood formation. (via Semantic Scholar)
Source: Web Of Science
Added: October 12, 2021

2021 journal article

Synthesis of AD-Dihydrodipyrrins Equipped with Latent Substituents of Native Chlorophylls and Bacteriochlorophylls

JOURNAL OF ORGANIC CHEMISTRY, 86(17), 11794–11811.

By: P. Wang n & J. Lindsey n

MeSH headings : Bacteriochlorophylls; Porphyrins
TL;DR: The analogous β-position of a lactone-pyrrole intermediate on the path to the dihydrodipyrrin also was successfully brominated, opening opportunities for late-stage diversification in the synthesis of (bacterio)chlorophylls. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: October 4, 2021

2021 journal article

Single-minded 2 is required for left-right asymmetric stomach morphogenesis

DEVELOPMENT, 148(17).

author keywords: right asymmetry; Stomach; Morphogenesis; Pitx2; Sim2; Down syndrome; Frog
MeSH headings : Animals; Anura; Basic Helix-Loop-Helix Transcription Factors / genetics; Basic Helix-Loop-Helix Transcription Factors / metabolism; Body Patterning; Embryo, Nonmammalian; Endoderm / embryology; Endoderm / metabolism; Gene Expression Regulation, Developmental; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Morphogenesis; Stomach / embryology; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is demonstrated that sim2 functions downstream of LR patterning cues to regulate key cellular properties and behaviors in the left stomach epithelium that drive asymmetric curvature, and has implications for dose-dependent roles of laterality factors in non-laterality-related birth defects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 27, 2021

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