Works Published in 2016
Displaying works 41 - 60 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Immunophenotypic and ultrastructural analysis of mast cells in hermansky-pudlak syndrome type-1: A possible connection to pulmonary fibrosis
PLoS ONE, 11(7).
Contributors: A. Kirshenbaum*, G. Cruse* , A. Desai*, G. Bandara*, M. Leerkes*, C. Lee *, E. Fischer *, . K.J. O'Brien
MeSH headings : Adult; Biomarkers; Case-Control Studies; Cell Line; Cells, Cultured; Chemotaxis; Cluster Analysis; Extracellular Matrix / metabolism; Female; Gene Expression Profiling; Hermanski-Pudlak Syndrome / diagnosis; Hermanski-Pudlak Syndrome / genetics; Hermanski-Pudlak Syndrome / metabolism; Humans; Imatinib Mesylate / pharmacology; Immunophenotyping; Lung / metabolism; Lung / pathology; Male; Mast Cells / drug effects; Mast Cells / metabolism; Mast Cells / ultrastructure; Membrane Proteins / genetics; Middle Aged; Mutation; Phenotype; Pulmonary Alveoli / metabolism; Pulmonary Alveoli / pathology; Pulmonary Fibrosis / etiology; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Young Adult
TL;DR:
The near-normalization of constitutive cytokine and matrix release following rescue by HPS1 transduction of HPM cells suggests that HPS-1 HuMCs may contribute to pulmonary fibrosis and constitute a target for therapeutic intervention.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
Source: ORCID
Added: February 11, 2019
2016 journal article
Hypoxia alters the expression, movement, and secretion of APP in retinal pigmented epithelial (RPE) cells
Investigative Ophthalmology and Visual Science, 57(12).
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Evaluation of the proliferative capacity of canine retinal pigment epithelial cells harvested from different regions of the fundus
Investigative Ophthalmology and Visual Science, 57(12).
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Effect of Plant Species, Fertilizer Acidity/Basicity, and Fertilizer Concentration on pH of Soilless Root Substrate
HORTSCIENCE, 51(12), 1596–1601.
author keywords: alkalinity; electrical conductivity; root media
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
University Counseling Centers' Perceptions and Experiences Pertaining to Emotional Support Animals
JOURNAL OF COLLEGE STUDENT PSYCHOTHERAPY, 30(4), 268–283.
author keywords: Assistance animal; counseling; emotional support animal; service dog
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Population pharmacokinetics of enrofloxacin in purple sea stars (Pisaster ochraceus) following an intracoelomic injection or extended immersion
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(11), 1266–1275.
MeSH headings : Animals; Chromatography, High Pressure Liquid; Enrofloxacin; Fluoroquinolones / pharmacokinetics; Half-Life; Injections, Intravenous; Microbial Sensitivity Tests; Starfish / metabolism
TL;DR:
Results suggested that the described enrofloxacin administration resulted in water vascular system fluid drug concentrations expected to exceed the minimum inhibitory concentration for many bacterial pathogens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Population pharmacokinetics of a single dose of meloxicam after oral and intramuscular administration to captive lesser flamingos (Phoeniconaias minor)
American Journal of Veterinary Research, 77(12), 1311–1317.
MeSH headings : Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Area Under Curve; Biological Availability; Birds / blood; Birds / metabolism; Female; Half-Life; Injections, Intravenous / veterinary; Male; Meloxicam; Thiazines / administration & dosage; Thiazines / pharmacokinetics; Thiazoles / administration & dosage; Thiazoles / pharmacokinetics
TL;DR:
In lesser flamingos, oral administration of meloxicam resulted in higher bioavailability and a longer elimination half-life than did IM administration, but the maximum plasma concentration was low and may be insufficient to provide analgesia in flamingos.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2016 journal article
Neural Stem Cells to Cerebral Cortex: Emerging Mechanisms Regulating Progenitor Behavior and Productivity
JOURNAL OF NEUROSCIENCE, 36(45), 11394–11401.
author keywords: cortical development; Cux2; cytokinesis; Fezf2; Kif20b; Lhx2; lineage; MADM; microcephaly; mouse; neurogenesis; Sp2; UPR
MeSH headings : Animals; Cell Differentiation / physiology; Cell Proliferation / physiology; Cerebral Cortex / cytology; Cerebral Cortex / physiology; Cytokinesis / physiology; Humans; Neurogenesis / physiology; Neuronal Plasticity / physiology; Neurons / cytology; Neurons / physiology
TL;DR:
Four aspects of corticogenesis are focused on: cytokinesis events that follow apical mitoses of NSCs; coordinating abscission with delamination from the apical membrane; timing of neurogenesis and its indirect regulation through emergence of intermediate progenitors; and capacity of single N SCs to generate the correct number and laminar fate of cortical neurons.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
8. Decent Work and Economic Growth
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Assessment of in vitro release of carboplatin from six carrier media
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(12), 1381–1386.
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Carboplatin / administration & dosage; Delayed-Action Preparations / administration & dosage; Drug Carriers / administration & dosage; Gelatin; Gels; Hemostatics; Microspheres; Neoplasms / drug therapy; Neoplasms / veterinary; Polymers
TL;DR:
The poloxamer copolymer gel and hemostatic gelatin sponge released carboplatin rapidly in vitro, whereas calcium sulfate beads did not.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 personal communication
Exploring the need to discuss onychectomy in depth with clients Response
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Exon skipping of Fc epsilon RI beta eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(49), 14115–14120.
Contributors: G. Cruse n , Y. Yin*, T. Fukuyama n, A. Desai*, G. Arthur n, W. Bäumer n, M. Beaven*, D. Metcalfe *
author keywords: mast cell; allergy; IgE receptor; oligonucleotides; dermatitis
MeSH headings : Animals; Calcium / metabolism; Cell Degranulation / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Cytokines / biosynthesis; Dermatitis, Allergic Contact / therapy; Disease Models, Animal; Female; Humans; Mast Cells / drug effects; Mast Cells / metabolism; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligonucleotides, Antisense / pharmacology; Oligonucleotides, Antisense / therapeutic use; Passive Cutaneous Anaphylaxis / genetics; RNA Splicing / drug effects; Receptors, IgE / genetics; Receptors, IgE / metabolism
TL;DR:
An innovative approach for targeting mast cells in vitro and in vivo is described using antisense oligonucleotide-mediated exon skipping of the β-subunit of the high-affinity IgE receptor (FcεRIβ) to eliminate surface high-Affinity Ig E receptor expression and function, rendering mast cells unresponsive to IgE-mediated activation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Eosinophilic meningomyelitis associated with T-cell lymphoma in a cat
VETERINARY CLINICAL PATHOLOGY, 45(4), 698–702.
author keywords: Cerebrospinal fluid; eosinophilic pleocytosis; feline; neoplasia; tetraparesis
MeSH headings : Animals; CD3 Complex / immunology; Cat Diseases / cerebrospinal fluid; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Cervical Cord / diagnostic imaging; Cervical Cord / pathology; Eosinophils / pathology; Inflammation / veterinary; Leukocytosis / diagnosis; Leukocytosis / pathology; Leukocytosis / veterinary; Lymphoma, T-Cell / cerebrospinal fluid; Lymphoma, T-Cell / diagnostic imaging; Lymphoma, T-Cell / pathology; Lymphoma, T-Cell / veterinary; Magnetic Resonance Imaging / veterinary; Male
TL;DR:
Necropsy revealed an asymmetric infiltration predominantly of the white matter, meninges, and nerve roots of the C4-C6 spinal cord segments by an unencapsulated, poorly demarcated neoplasm composed of atypical lymphocytes admixed with eosinophils, causing perivascular hemorrhage and lytic necrosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Cytokine and chemokine profiles of aqueous humor and serum in horses with uveitis measured using multiplex bead immunoassay analysis
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 182, 43–51.
author keywords: Uveitis; Multiplex; Horse; Cytokine; Chemokine; Leptospirosis
MeSH headings : Animals; Aqueous Humor / immunology; Biomarkers / blood; Biomarkers / metabolism; Chemokines / blood; Chemokines / metabolism; Cytokines / blood; Cytokines / metabolism; Horse Diseases / blood; Horse Diseases / diagnosis; Horse Diseases / immunology; Horses; Immunoassay; Inflammation Mediators / blood; Inflammation Mediators / metabolism; Leptospirosis / blood; Leptospirosis / immunology; Leptospirosis / veterinary; Uveitis / blood; Uveitis / immunology; Uveitis / veterinary
TL;DR:
The anti-inflammatory cytokine IL-10 and the pro- inflammatory cytokine IP-10 appear to play an important role in ERU.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Pharmacokinetics of voriconazole after intravenous and oral administration to healthy cats
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(9), 931–939.
MeSH headings : Administration, Intravenous; Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / pharmacokinetics; Biological Availability; Cats; Chemistry, Pharmaceutical; Cross-Over Studies; Half-Life; Suspensions; Tablets; Voriconazole / administration & dosage; Voriconazole / pharmacokinetics
TL;DR:
Voriconazole had excellent oral bioavailability and a long half-life in cats and increased plasma concentrations in the target range but increased, which suggested drug accumulation during long-term administration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Forecasting United States heartworm Dirofilaria immitis prevalence in dogs
PARASITES & VECTORS, 9.
author keywords: Autoregression; CAR Model; Head-banging; Heartworm; Kriging; Prevalence; Spatio-temporal correlation
MeSH headings : Animals; Climate; Culicidae / growth & development; Dirofilaria immitis / isolation & purification; Dirofilariasis / epidemiology; Dirofilariasis / parasitology; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Forecasting; Models, Statistical; Prevalence; Spatio-Temporal Analysis; United States / epidemiology
TL;DR:
The forecast presented herein can a priori alert veterinarians to areas expected to see higher than normal heartworm activity and may prove useful for forecasting other diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 conference paper
Coalescence prevention algorithm for level set method
Proceedings of the asme fluids engineering division summer meeting, 2016, vol 1b.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Home-Range Size in Large-Bodied Carnivores as a Model for Predicting Neandertal Territory Size
EVOLUTIONARY ANTHROPOLOGY, 25(3), 117–123.
author keywords: mobility; Pleistocene; Mousterian; Micoquian
MeSH headings : Animals; Anthropology, Physical; History, Ancient; Homing Behavior / physiology; Models, Biological; Neanderthals / physiology; Wolves / physiology
TL;DR:
It is shown that Neandertals had stocky, short‐limbed physiques that were energetically costly to move and lived in relatively unproductive Pleistocene environments that may have required greater movement to deal with problems of biodepletion and resource patchiness.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses
NEUROGASTROENTEROLOGY AND MOTILITY, 28(9), 1317–1329.
author keywords: cholinergic neurons; early life adversity; enteric nervous system development; irritable bowel syndrome; porcine model
MeSH headings : Animals; Cholinergic Neurons / metabolism; Disease Models, Animal; Enteric Nervous System / metabolism; Female; Irritable Bowel Syndrome / metabolism; Male; Motor Neurons / metabolism; Sex Factors; Stress, Psychological / metabolism; Swine; Up-Regulation; Weaning
TL;DR:
A porcine model of ELA, early weaning stress (EWS), is utilized to investigate the influence of Ela on the development and function of the enteric nervous system (ENS).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Defining the local nerve blocks for feline distal thoracic limb surgery: a cadaveric study
JOURNAL OF FELINE MEDICINE AND SURGERY, 18(10), 838–845.
MeSH headings : Animals; Cadaver; Cats / anatomy & histology; Female; Forelimb / innervation; Forelimb / surgery; Male; Median Nerve / anatomy & histology; Nerve Block / veterinary; Radial Nerve / anatomy & histology; Ulnar Nerve / anatomy & histology
TL;DR:
A four-point injection method based on cadaveric dissections and tested using dye injections may be an effective perioperative analgesia technique for feline distal thoracic limb procedures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Comprehensive genomic characterization of five canine lymphoid tumor cell lines
BMC Veterinary Research, 12.
Source: NC State University Libraries
Added: August 6, 2018
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