Works Published in 2013

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Displaying works 41 - 60 of 116 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2013 journal article

Design and fabrication of uniquely shaped thiol–ene microfibers using a two-stage hydrodynamic focusing design

Lab on a Chip, 13(15), 3105.

By: D. Boyd*, A. Shields*, P. Howell* & F. Ligler*

MeSH headings : Equipment Design; Hydrodynamics; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Polymerization; Polymers / chemistry; Sulfhydryl Compounds / chemistry
TL;DR: This work describes how to fabricate the next generation of fibers predesigned to have a much more complex geometry, as exemplified by the "double anchor" shape, using a two-stage hydrodynamic focusing system. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2013 journal article

Catch and Release: Integrated System for Multiplexed Detection of Bacteria

Analytical Chemistry, 85(10), 4944–4950.

By: J. Verbarg*, W. Plath*, L. Shriver-Lake*, P. Howell*, J. Erickson*, J. Golden*, F. Ligler*

MeSH headings : Bacteria / cytology; Bacteria / isolation & purification; Flow Cytometry / instrumentation; Humans; Immunomagnetic Separation / instrumentation; Microarray Analysis / instrumentation; Systems Integration
TL;DR: An integrated system with automated immunomagnetic separation and processing of fluidic samples was demonstrated for multiplexed optical detection of bacterial targets and the potential for using the MagTrap to concentrate target from larger volumes of sample prior to the addition of assay reagents was demonstrated. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2013 journal article

Automated processing integrated with a microflow cytometer for pathogen detection in clinical matrices

Biosensors and Bioelectronics, 40(1), 10–16.

By: J. Golden*, J. Verbarg*, P. Howell*, L. Shriver-Lake* & F. Ligler*

author keywords: Integrated sample processing; Microfluidics; Flow cytometry; Magnetic microspheres; Multiplexed analysis
MeSH headings : Biosensing Techniques / instrumentation; Equipment Design; Equipment Failure Analysis; Escherichia coli O157 / isolation & purification; Flow Cytometry / instrumentation; Immunomagnetic Separation / instrumentation; Reproducibility of Results; Robotics / instrumentation; Sensitivity and Specificity; Systems Integration
TL;DR: A spinning magnetic trap for automated sample processing was integrated with a microflow cytometer capable of simultaneously detecting multiple targets to provide an automated sample-to-answer diagnosis in 40 min, demonstrating the potential for quantification of pathogen load in buffer and serum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Crossref
Added: August 28, 2020

2013 journal article

Simultaneous assay for ten bacteria and toxins in spiked clinical samples using a microflow cytometer

Analytical and Bioanalytical Chemistry, 405(16), 5611–5614.

By: L. Shriver-Lake*, J. Golden*, L. Bracaglia* & F. Ligler*

author keywords: Microflow cytometry; Multiplexed analysis; Bacterial detection; Toxin detection; Biosensor
MeSH headings : Bacteria / isolation & purification; Bacterial Toxins / analysis; Bacterial Toxins / blood; Case-Control Studies; Flow Cytometry / instrumentation; Flow Cytometry / methods; Humans; Immunoassay; Limit of Detection; Random Allocation; Ricin / analysis
TL;DR: The multiplexed assays using the microflow cytometer demonstrated detection limits similar to or better than other reported antibody-based methods for pathogen detection (ELISA, lateral flow, array biosensors) and achieved limits of detection equivalent to those for spiked buffer samples. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2013 journal article

Microfabrication: Rapid and Continuous Hydrodynamically Controlled Fabrication of Biohybrid Microfibers (Adv. Funct. Mater. 6/2013)

Advanced Functional Materials, 23(6), 697–697.

By: M. Daniele*, S. North*, J. Naciri*, P. Howell*, S. Foulger*, F. Ligler*, A. Adams*

Source: Crossref
Added: August 28, 2020

2013 conference paper

Real-time implementation of a self-recovery EMG pattern recognition interface for artificial arms

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 5926–5929.

Contributors: X. Zhang*, H. Huang* & Q. Yang*

Event: 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

MeSH headings : Algorithms; Artificial Limbs; Electromyography / methods; Equipment Design; Humans; Pattern Recognition, Automated / methods; Prostheses and Implants; Software
TL;DR: A novel self-recovery module consisting of multiple sensor fault detectors and a fast LDA classifier retraining strategy has been developed to immediately recover the classification performance from signal disturbances. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 17, 2020

2013 conference paper

Design and implementation of a low power mobile CPU based embedded system for artificial leg control

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 5769–5772.

Event: 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

MeSH headings : Algorithms; Artificial Limbs; Brain-Computer Interfaces; Discriminant Analysis; Electromyography; Humans; Leg; Pattern Recognition, Automated; Software; Support Vector Machine
TL;DR: By utilizing the architectural features of a mobile embedded CPU, this paper is able to implement the decision-making algorithm, based on neuromuscular phase-dependant support vector machines (SVM), with exceptional accuracy and processing speed. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 17, 2020

2013 conference paper

Decoding movement intent of patient with multiple sclerosis for the powered lower extremity exoskeleton

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 4957–4960.

Contributors: F. Zhang* & H. Huang*

Event: 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

MeSH headings : Algorithms; Biomechanical Phenomena; Electromyography / methods; Female; Humans; Intention; Lower Extremity / physiology; Monitoring, Ambulatory / instrumentation; Monitoring, Ambulatory / methods; Movement; Multiple Sclerosis / physiopathology; Pattern Recognition, Automated; Posture; Reproducibility of Results; Signal Processing, Computer-Assisted; Thigh / pathology; Walking / physiology
TL;DR: This study showed that during activity performance clear modulation of muscle activity in the lower extremities was observed for the MS patient, and promising results indicate the potential of designed intent recognition interface for volitional control of powered lower extremity exoskeletons. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 17, 2020

2013 conference paper

Design of an expert system to automatically calibrate impedance control for powered knee prostheses

2013 IEEE 13th International Conference on Rehabilitation Robotics (ICORR). Presented at the 2013 IEEE 13th International Conference on Rehabilitation Robotics (ICORR 2013).

Event: 2013 IEEE 13th International Conference on Rehabilitation Robotics (ICORR 2013)

MeSH headings : Calibration; Electric Impedance; Expert Systems; Humans; Knee Prosthesis; Walking
TL;DR: Preliminary experimental results demonstrated that the developed expert system can converge the user's knee profile and gait timing to the desired values within 2 minutes, which indicates the promise of the designed expert system for quick and accuracy impedance calibration, which can significantly improve the practical value of powered lower limb prosthesis. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 17, 2020

2013 journal article

Source Selection for Real-Time User Intent Recognition Toward Volitional Control of Artificial Legs

IEEE Journal of Biomedical and Health Informatics, 17(5), 907–914.

Contributors: F. Zhang* & H. Huang*

author keywords: Artificial legs; data source selection; real time; user intent recognition; volitional control
MeSH headings : Algorithms; Amputees; Artificial Limbs; Biomechanical Phenomena; Electromyography / instrumentation; Electromyography / methods; Humans; Man-Machine Systems; Muscle, Skeletal / physiology; Signal Processing, Computer-Assisted / instrumentation; Thigh / physiology
TL;DR: The results showed that EMG signals and ground reaction forces/moments were more informative than prosthesis kinematics and a protocol was suggested for determining the informative data sources and sensor configurations for future development of volitional control of powered artificial legs. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 17, 2020

2013 conference paper

Terrain recognition improves the performance of neural-machine interface for locomotion mode recognition

2013 International Conference on Computing, Networking and Communications (ICNC), 87–91.

Contributors: D. Wang*, L. Du* & H. Huang*

Event: 2013 International Conference on Computing, Networking and Communications (ICNC 2013)

Sources: Crossref, NC State University Libraries, ORCID
Added: January 17, 2020

2013 conference paper

Improving the performance of a neural-machine interface for prosthetic legs using adaptive pattern classifiers

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 1571–1574.

Contributors: L. Du*, F. Zhang*, H. He* & H. Huang*

Event: 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

MeSH headings : Algorithms; Amputees; Artificial Limbs; Brain-Computer Interfaces; Electromyography; Femur / surgery; Humans; Leg / physiopathology; Signal Processing, Computer-Assisted; Software; Support Vector Machine
TL;DR: The preliminary results showed that the NMI with adaptive classifier produced more consistent performance over time than the classifier without adaptation, indicating the potential of using adaptive classifiers to improve the N MI reliability for neural control of powered prosthetic legs. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 17, 2020

2013 conference paper

Electromagnetic levitation platform for wireless study of insect flight neurophysiology

2013 35th annual international conference of the ieee engineering in medicine and biology society (embc), 1720–1723.

By: A. Verderber n, M. McKnight n & A. Bozkurt n

MeSH headings : Animals; Electrodes, Implanted; Electromagnetic Phenomena; Electromyography; Flight, Animal / physiology; Manduca / physiology; Muscle Contraction; Muscles / physiology; Video Recording; Wireless Technology
TL;DR: An electromagnetic levitation platform for use in a light emitting diode (LED) arena based virtual reality environment was developed for wireless recording of neural and neuromuscular signals from the flight related muscle groups in Manduca sexta. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

In Vivo Demonstration of Cancer Molecular Imaging with Ultrasound Radiation Force and Buried-Ligand Microbubbles

MOLECULAR IMAGING, 12(6).

TL;DR: The use of acoustically active buried-ligand microbubbles for ultrasound molecular imaging bridges the demand for low immunogenicity with the necessity of maintaining targeting efficacy and imaging conspicuity in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Mechanical energy profiles of the combined ankle-foot system in normal gait: Insights for prosthetic designs

Gait & Posture, 38(4), 818–823.

By: K. Takahashi & S. Stanhope

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Targeted drug delivery with focused ultrasound-induced blood-brain barrier opening using acoustically-activated nanodroplets

JOURNAL OF CONTROLLED RELEASE, 172(3), 795–804.

By: C. Chen*, P. Sheeran n, S. Wu*, O. Olumolade*, P. Dayton n & E. Konofagou*

author keywords: Acoustically-activated nanodroplets; Phase-shift droplets; Microbubbles; Focused ultrasound; Blood
MeSH headings : Acoustics; Animals; Blood-Brain Barrier / metabolism; Contrast Media / chemistry; Contrast Media / metabolism; Dextrans / administration & dosage; Drug Delivery Systems / methods; Hippocampus / metabolism; Male; Mice; Mice, Inbred C57BL; Nanostructures / chemistry; Sonication / methods
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Sensitization of Transforming Growth Factor-beta Signaling by Multiple Peptides Patterned on DNA Nanostructures

BIOMACROMOLECULES, 14(12), 4157–4160.

By: R. Pedersen*, E. Loboa n & T. LaBean n

MeSH headings : Animals; Biotin / chemistry; Cell Line; DNA / chemistry; Drug Carriers / chemistry; Drug Carriers / pharmacology; Genes, Reporter; Mice; Nanostructures / chemistry; Nanostructures / ultrastructure; Peptide Fragments / chemistry; Peptide Fragments / pharmacology; Receptors, Transforming Growth Factor beta / metabolism; Signal Transduction; Streptavidin / chemistry; Transforming Growth Factor beta / pharmacology; Transforming Growth Factor beta / physiology
TL;DR: This work reports sensitization of a cellular signaling pathway by addition of functionalized DNA nanostructures, an important initial step toward realization of DNA as a self-assembling and biologically compatible material for use in tissue engineering and drug delivery. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 article

Nanomaterials in Analytical Chemistry

Ligler, F. S., & White, H. S. (2013, December 3). ANALYTICAL CHEMISTRY, Vol. 85, pp. 11161–11162.

MeSH headings : Chemistry, Analytic / trends; Nanostructures / chemistry
Source: Web Of Science
Added: August 6, 2018

2013 journal article

In Situ Electrode Calibration Strategy for Voltammetric Measurements In Vivo

ANALYTICAL CHEMISTRY, 85(23), 11568–11575.

By: J. Roberts n, J. Toups n, E. Eyualem n, G. McCarty n & L. Sombers n

MeSH headings : Animals; Calibration; Electrochemical Techniques / methods; Electrodes, Implanted; Flow Injection Analysis / methods; Male; Rats; Rats, Sprague-Dawley
TL;DR: A model that utilizes information contained in the background charging current to predict electrode sensitivity to dopamine, ascorbic acid, hydrogen peroxide, and pH shifts at any point in an electrochemical experiment is developed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Impacts of feedstock composition on alcohol yields and greenhouse gas emissions from the NREL thermochemical ethanol conversion process

BioResources, 8(4), 5261–5278.

By: J. Daystar n, R. Venditti n, R. Gonzalez, H. Jameel n, M. Jett n & C. Reeb n

Source: NC State University Libraries
Added: August 6, 2018

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