Works Published in 2021
Displaying works 21 - 40 of 263 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2021 article
Teosinte <i>mexicana</i> introgression modulates phosphatidylcholine levels and maize flowering time
Barnes, A. C., Rodrı́guez-Zapata Fausto, Blöcher-Juárez, K. A., Gates, D. J., Kur, A., Wang, L., … Rellán-Álvarez, R. (2021, January 26). [], Vol. 1.
doi.org (repository)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: April 12, 2022
2021 article
A spatiotemporal recommendation engine for malaria control
Guan, Q., Reich, B. J., & Laber, E. B. (2021, April 10). BIOSTATISTICS, Vol. 4.
author keywords: Infectious disease; Malaria; Resource allocation; Sequential optimization; Satiotemporal model
MeSH headings : Bayes Theorem; Humans; Malaria / prevention & control; Resource Allocation
TL;DR:
The estimated optimal policy under the proposed framework improves the cumulative long-term outcome compared with naive approaches in both simulation experiments and application to malaria interventions in the Democratic Republic of the Congo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 28, 2022
2021 journal article
Lessons learned from the rapid development of a statewide simulation model for predicting COVID-19's impact on healthcare resources and capacity
PLOS ONE, 16(11).
Ed(s): A. Villaverde
MeSH headings : COVID-19 / epidemiology; Delivery of Health Care; Forecasting; Hospital Bed Capacity / statistics & numerical data; Hospitalization / trends; Humans; Intensive Care Units / trends; North Carolina / epidemiology; Pandemics / statistics & numerical data
TL;DR:
RTI adapted a previously developed geospatially explicit healthcare facility network model to predict COVID-19’s impact on healthcare resources and capacity in NC and described key steps taken, challenges faced, and lessons learned from adapting and implementing the model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 7, 2022
2021 journal article
Urban Park Use During the COVID-19 Pandemic: Are Socially Vulnerable Communities Disproportionately Impacted?
FRONTIERS IN SUSTAINABLE CITIES, 3.
author keywords: coronavirus; COVID-19; environmental justice; equity; greenspace; health; outdoor recreation; race
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 28, 2022
2021 journal article
Detection and classification of neurons and glial cells in the MADM mouse brain using RetinaNet
PLOS ONE, 16(9).
MeSH headings : Animals; Brain; Cell Differentiation; Mice; Neuroglia; Neurons
TL;DR:
Object detection networks (neural networks) are utilized to detect and classify targets in complex microscopy images, while simplifying data annotation, and merging the predictions of the two computational models significantly improved the automated cell counting of glial clusters.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
8. Decent Work and Economic Growth
(OpenAlex)
Source: Web Of Science
Added: February 28, 2022
2021 journal article
Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species
PLOS COMPUTATIONAL BIOLOGY, 17(9).
MeSH headings : Animals; Biomarkers, Tumor / genetics; Bone Neoplasms / genetics; Bone Neoplasms / veterinary; Computational Biology; Dog Diseases / classification; Dog Diseases / genetics; Dogs; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Lung Neoplasms / genetics; Lung Neoplasms / veterinary; Lymphoma, B-Cell / genetics; Lymphoma, B-Cell / veterinary; Lymphoma, T-Cell / genetics; Lymphoma, T-Cell / veterinary; Melanoma / genetics; Melanoma / veterinary; Molecular Sequence Annotation; Molecular Targeted Therapy; Neoplasms / classification; Neoplasms / genetics; Neoplasms / veterinary; Oncogenes; Osteosarcoma / genetics; Osteosarcoma / veterinary; Species Specificity; Translational Research, Biomedical
TL;DR:
An experimental-bioinformatic protocol is developed that analyzes canine transcriptomics data in the context of existing human data to evaluate comparative relevance of canine to human cancer, and demonstrates transferability of classification models from canines to humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 21, 2022
2021 journal article
Effective Treatment Strategies for the Removal of Antibiotic-Resistant Bacteria, Antibiotic-Resistance Genes, and Antibiotic Residues in the Effluent From Wastewater Treatment Plants Receiving Municipal, Hospital, and Domestic Wastewater: Protocol for a Systematic Review
JMIR RESEARCH PROTOCOLS.
author keywords: antimicrobial resistance; antimicrobial-resistant bacteria; antibiotic-resistant bacteria; antimicrobial-resistance genes; antibiotic-resistance genes; antibiotics; antibiotic residues; wastewater treatment plant; effluent; systematic review
TL;DR:
A systematic review is conducted to determine the most effective treatment strategies for the removal of ARB, ARGs, and antibiotic residues from the treated effluent disposed into the environment from WWTPs that receive municipal, hospital, and domestic discharge.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 21, 2022
2021 journal article
Mapping the dynamic transfer functions of eukaryotic gene regulation
CELL SYSTEMS, 12(11), 1079-+.
MeSH headings : Chromatin / genetics; Eukaryota / genetics; Gene Expression Regulation / genetics; Promoter Regions, Genetic / genetics; Signal Transduction
TL;DR:
It is determined that chromatin state could be used to tune mutual information and expression levels, as well as completely alter the input-output transfer function of the promoter, which unlocks the information-rich content of eukaryotic gene regulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 31, 2022
2021 journal article
Randomized, Placebo-Controlled Prospective Clinical Trial Evaluating the Efficacy of the Assisi Anti-anxiety Device (Calmer Canine) for the Treatment of Canine Separation Anxiety
FRONTIERS IN VETERINARY SCIENCE, 8.
author keywords: dog; pulsed electro-magnetic field (PEMF); behavior; fear; separation distress; separation-related behaviors
TL;DR:
This study supports the efficacy and safety of this PEMF device for treatment of SA in dogs and assesses its impact on other anxieties or combination of anxiety disorders in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: January 18, 2022
2021 article
Comparative Assessment of Pesticide Exposures in Domestic Dogs and Their Owners Using Silicone Passive Samplers and Biomonitoring
Wise, C. F., Hammel, S. C., Herkert, N. J., Ospina, M., Calafat, A. M., Breen, M., & Stapleton, H. M. (2021, December 29). ENVIRONMENTAL SCIENCE & TECHNOLOGY.
author keywords: exposure; wristband; silicone; biomonitoring; pesticide; dog
MeSH headings : Animals; Biological Monitoring; Chlorpyrifos; Dogs; Environmental Exposure / analysis; Environmental Monitoring; Humans; Pesticides / analysis; Silicones
TL;DR:
It is suggested that people and their dogs have similar pesticide exposures in a home environment as well as targeted gas chromatography-mass spectrometry analyses suggest.
(via Semantic Scholar)
Source: Web Of Science
Added: January 18, 2022
2021 article
In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A
Xiao, X., Sarma, S., Menegatti, S., Crook, N., Magness, S. T., & Hall, C. K. (2021, December 29). ACS CHEMICAL BIOLOGY, Vol. 12.
MeSH headings : Bacterial Toxins / antagonists & inhibitors; Bacterial Toxins / chemistry; Computer Simulation; Drug Design; Enterotoxins / antagonists & inhibitors; Enterotoxins / chemistry; Models, Molecular; Peptides / chemistry; Peptides / pharmacology; Protein Binding; Protein Conformation; Protein Domains; Reproducibility of Results
TL;DR:
This work used a computational strategy that integrates a peptide binding design algorithm and explicit-solvent atomistic molecular dynamics simulation to determine promising toxin A-targeting peptides that can recognize and bind to the catalytic site of the TcdA glucosyltransferase domain (GTD).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022
2021 journal article
TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA
NUCLEIC ACIDS RESEARCH, 49(22), 13000–13018.
MeSH headings : Animals; DNA / chemistry; DNA / genetics; DNA / metabolism; HeLa Cells; Humans; Mice, Inbred C57BL; Microscopy, Atomic Force; Nucleic Acid Conformation; Protein Binding; Shelterin Complex / genetics; Shelterin Complex / metabolism; Telomere / genetics; Telomere / metabolism; Telomere-Binding Proteins / genetics; Telomere-Binding Proteins / metabolism; Telomeric Repeat Binding Protein 2 / genetics; Telomeric Repeat Binding Protein 2 / metabolism
TL;DR:
A molecular model in which TIN2 functions as an architectural protein to promote TRF2-mediated trans and cis higher-order nucleic acid structures at telomeres is proposed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022
2021 journal article
Human skin triglycerides prevent bed bug (Cimex lectularius L.) arrestment
SCIENTIFIC REPORTS, 11(1).
MeSH headings : Adult; Animals; Bedbugs / metabolism; Bedbugs / pathogenicity; Cues; Feeding Behavior; Female; Host-Parasite Interactions; Humans; Locomotion; Male; Middle Aged; Odorants; Pheromones / metabolism; Skin / metabolism; Skin / parasitology; Triglycerides / metabolism
TL;DR:
Results provide strong evidence that the complex of human skin compounds serve as multifunctional semiochemicals for bed bugs, with some odorants attracting host-seeking stages, and others (TAGs and possibly other compounds) preventing bed bug arrestment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 10, 2022
2021 journal article
Epigenetic Dysregulation of KCNK9 Imprinting and Triple-Negative Breast Cancer
CANCERS, 13(23).
author keywords: triple negative breast cancer; KCNK9; epigenetics; imprinting
TL;DR:
Evidence is provided that hypomethylation of the KNCK9 DMR/TASK3 overexpression may serve as a marker of risk and a target for prevention of TNBC, particularly in African American women.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: January 10, 2022
2021 journal article
Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization
METABOLITES, 11(12).
author keywords: metabolites; dicationic reagent; ambient ionization; IR-MALDESI; mass spectrometry imaging
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 10, 2022
2021 personal communication
From IgZ to IgT: A Call for a Common Nomenclature for Immunoglobulin Heavy Chain Genes of Ray-Finned Fish
Dornburg, A., Ota, T., Criscitiello, M. F., Salinas, I., Sunyer, J. O., Magadan, S., … Yoder, J. A. (2021, December 1).
MeSH headings : Animals; Fish Proteins / genetics; Fishes / genetics; Genes, Immunoglobulin Heavy Chain; Phylogeny; Terminology as Topic; Zebrafish / genetics
TL;DR:
Ray-finned fishes comprise more than half the *60,000 known vertebrate species, and are pivotal to the functionality of aquatic ecosystems and success of global multibillion dollar industries, necessitates that immunology and translational medicine research groups investigating the immune system in one or a number of species employ a common language for describing homologous immune components.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 10, 2022
2021 article
Environmental exposures contribute to respiratory and allergic symptoms among women living in the banana growing regions of Costa Rica
Alhanti, B., Joode, B. van W., Martinez, M. S., Mora, A. M., Gamboa, L. C., Reich, B., … Hoppin, J. A. (2021, December 30). OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol. 12.
author keywords: asthma; respiratory disease; allergy; pesticide; agriculture
MeSH headings : Asthma / epidemiology; Cohort Studies; Costa Rica / epidemiology; Eczema / epidemiology; Environmental Exposure / adverse effects; Exanthema / epidemiology; Female; Humans; Hypersensitivity / epidemiology; Musa; Pesticides / adverse effects; Respiratory Tract Diseases / epidemiology; Rhinitis / epidemiology; Smoke / adverse effects
TL;DR:
Findings suggest that environmental exposure to both pesticides and smoke may impact respiratory and skin-related allergic outcomes in women.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 10, 2022
2021 article
Pathogenic Vibrio parahaemolyticus Increase in Intertidal-Farmed Oysters in the Mid-Atlantic Region, but Only at Low Tide
Ben-Horin, T., Audemard, C., Calvo, L., Reece, K. S., & Bushek, D. (2021, December 13). NORTH AMERICAN JOURNAL OF AQUACULTURE, Vol. 12.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 3, 2022
2021 article
The evolution of innate immune receptors: investigating the diversity, distribution, and phylogeny of immune recognition across eukaryotes
Buckley, K. M., & Yoder, J. A. (2021, December 15). IMMUNOGENETICS, Vol. 12.
MeSH headings : Eukaryota; Evolution, Molecular; Immunity, Innate / genetics; Phylogeny; Receptors, Immunologic
TL;DR:
The diversity of IIRs from plants, vertebrates, invertebrate deuterostomes, a range of protostome invertebrates and basal metazoans is explored, and it is suggested that, to fully understand eukaryotic immune systems, further investigations of these proteins are warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 3, 2022
2021 journal article
Responsible Innovation Definitions, Practices, and Motivations from Nanotechnology Researchers in Food and Agriculture
NanoEthics, 15(3), 229–243.
author keywords: Responsible innovation; Nanotechnology; Food; Agriculture; Governance; Qualitative research
TL;DR:
Investigating how researchers in the field of nanotechnology for food and agriculture (nano-agrifoods) define and practice RI, as well as what motivations they see for pursuing RI found that nano-agRifood researchers largely focused their descriptions of RI definitions, practices, and motivations around a narrow envisioning of the RI principle of anticipation — emphasizing product safety, efficacy, and efficiency.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: January 3, 2022
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