Works Published in 2023
Displaying works 101 - 120 of 133 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2023 journal article
Genetic Modifiers of Cystic Fibrosis Lung Disease Severity
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 207(10), 1324–1333.
author keywords: cystic fibrosis; whole-genome sequencing; lung disease severity; GWAS/TWAS; pathway analyses
MeSH headings : Humans; Cystic Fibrosis / genetics; Genome-Wide Association Study / methods; Cystic Fibrosis Transmembrane Conductance Regulator / genetics; Patient Acuity; Lung; Microtubule-Associated Proteins / genetics
TL;DR:
This pre- modulator genomic, transcriptomic, and pathway association study of 7,840 pwCF will facilitate mechanistic and post-modulator genetic studies and, development of novel therapeutics for CF lung disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 16, 2023
2023 journal article
Whole exome sequencing analysis of canine urothelial carcinomas without BRAF V595E mutation: Short in-frame deletions in BRAF and MAP2K1 suggest alternative mechanisms for MAPK pathway disruption
PLOS GENETICS, 19(4).
MeSH headings : Dogs; Animals; Humans; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / veterinary; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / veterinary; Proto-Oncogene Proteins B-raf / genetics; Exome Sequencing; Mutation; MAP Kinase Kinase 1 / genetics
TL;DR:
It is suggested that short in-frame deletions within BRAF exon 12 and MAP2K1 exons 2 and 3 in UDV595E cases are alternative MAPK-pathway activating events that may have significant therapeutic implications for selecting first-line treatment for canine UC.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 15, 2023
2023 article
Editorial: Women in psychiatry 2022: Addictive disorders
Lynch, W. J., Towers, E. B., & Rissman, E. F. (2023, April 11). FRONTIERS IN PSYCHIATRY, Vol. 14.
author keywords: substance use disorder; women; opioids; editorial; gender bias
TL;DR:
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: May 15, 2023
2023 journal article
RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients
PHARMACEUTICALS, 16(5).
author keywords: GWAS; chemotherapy; sensitivity; resistance; glioma; drug response; temozolomide; knockdown; overexpression; pharmacogenomics; gene expression; RYK
TL;DR:
The findings suggest that RYK expression may serve as an important prognostic or predictor of TMZ response and survival for glioma patients and a combination of RyK expression and MGMT status could serve as a additional biomarker for improved survival.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 12, 2023
2023 journal article
Physiological and life history responses in a mayfly (Callibaetis floridanus) inhabiting ponds with saltwater intrusion
FRONTIERS IN ECOLOGY AND EVOLUTION, 11.
author keywords: mayfly; saline adaptation; ion fluxes; saltwater intrusion; plasticity
TL;DR:
Analysis of life-history outcomes and physiological plasticity in a population of Callibaetis floridanus from a coastal pond that routinely experiences saltwater intrusion suggests that saline adapted C. floridas may be more energetically challenged in dilute conditions, which differs from previous observations in other mayfly species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: May 1, 2023
2023 article
Predicting Concentration- and Ionic-Strength-Dependent Air-Water Interfacial Partitioning Parameters of PFASs Using Quantitative Structure-Property Relationships (QSPRs)
Stults, J. F., Choi, Y. J., Rockwell, C., Schaefer, C. E., Nguyen, D. D., Knappe, D. R. U., … Higgins, C. P. (2023, March 24). ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol. 3.
author keywords: PFAS air-water interfacial adsorption; QSPR; nonequilibrium; unsaturated columns; pan film
MeSH headings : Water; Fluorocarbons / analysis; Ethers; Alkanesulfonic Acids; Water Pollutants, Chemical / analysis; Osmolar Concentration
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 17, 2023
2023 journal article
ToxicR: A computational platform in R for computational toxicology and dose–response analyses
Computational Toxicology, 25, 100259.
TL;DR:
The Biostatistics and Computational Biology Branch of the National Institute of Environmental Health Sciences, in cooperation with the National Toxicology Program and US Environmental Protection Agency, developed ToxicR, an open-source R programming package that implements many of the standard analyses used by the NTP and EPA.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: April 12, 2023
2023 journal article
Histological evaluations of organ tissues reveal sublethal effects in a freshwater mussel (Villosa iris) exposed to chloride and potassium concentrations below benchmark estimates
AQUATIC TOXICOLOGY, 258.
author keywords: Freshwater mussels; Histology; Salinity; North Fork Holston River; Potassium; Chloride
MeSH headings : Animals; Benchmarking; Bivalvia; Chlorides / analysis; Ecosystem; Fresh Water; Potassium; Unionidae; United States; Water Pollutants, Chemical / toxicity
TL;DR:
Significant histological differences between control and baseline (day-0 sample) mussels were observed, suggesting the need for further study on the effects of captivity during longer-term laboratory experiments, and sublethal effects to digestive glands and kidneys were below reported effect.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 11, 2023
2023 article
Ancient Fish Lineages Illuminate Toll-Like Receptor Diversification in Early Vertebrate Evolution
Carlson, K. B., Nguyen, C., Wcisel, D. J., Yoder, J. A., & Dornburg, A. (2023, April 6).
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: April 7, 2023
2023 journal article
The dogs of Chernobyl: Demographic insights into populations inhabiting the nuclear exclusion zone
SCIENCE ADVANCES, 9(9).
MeSH headings : Dogs; Animals; Chernobyl Nuclear Accident; Environment; Disasters; Environmental Pollution; Demography
TL;DR:
This study presents the first characterization of a domestic species in Chernobyl, establishing their importance for genetic studies into the effects of exposure to long-term, low-dose ionizing radiation.
(via Semantic Scholar)
Source: Web Of Science
Added: April 4, 2023
2023 article
PARP1 associates with R-loops to promote their resolution and genome stability
Laspata, N., Kaur, P., Mersaoui, S. Y., Muoio, D., Liu, Z. S., Bannister, M. H., … Fouquerel, E. (2023, February 16). NUCLEIC ACIDS RESEARCH, Vol. 2.
MeSH headings : Humans; DNA / chemistry; DNA Repair; Genomic Instability; Poly (ADP-Ribose) Polymerase-1 / genetics; Poly (ADP-Ribose) Polymerase-1 / metabolism; R-Loop Structures; RNA / chemistry
TL;DR:
It is demonstrated that PARP1 binds R-loops in vitro and associates with R-loop formation sites in cells which activates its ADP-ribosylation activity, and highlights thatPARP1 is a suppressor of R- loop-associated genomic instability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 20, 2023
2023 journal article
Optimization of Biotinylated RNA or DNA Pull-Down Assays for Detection of Binding Proteins: Examples of IRP1, IRP2, HuR, AUF1, and Nrf2
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(4).
author keywords: RNA pull-down; DNA pull-down; biotin; streptavidin; IRP2; HuR; AUF1; Nrf2; ferritin; IRP-IRE
MeSH headings : Humans; Carrier Proteins / chemistry; DNA / chemistry; Iron / metabolism; Iron Regulatory Protein 1 / chemistry; Iron Regulatory Protein 2 / chemistry; NF-E2-Related Factor 2 / chemistry; RNA / chemistry; Streptavidin / metabolism; Biotinylation; Chromatography, Affinity / methods
TL;DR:
The step-by step optimization of pull-down for IRP with a 5′-biotinylated stem-loop IRE (iron-responsive element) RNA, HuR, and AUF1 with an AU-rich RNA element and Nrf2 binding to an antioxidant- responsive element (ARE) enhancer in the human ferritin H gene is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 20, 2023
2023 journal article
Pilot-scale biofiltration of 1,4-dioxane at drinking water-relevant concentrations
WATER RESEARCH, 231.
author keywords: Biofiltration; Cometabolism; Adsorption; Emerging contaminants
MeSH headings : Drinking Water; Pilot Projects; Water Pollutants, Chemical / analysis; Water Purification / methods; Charcoal / chemistry; Filtration / methods
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 13, 2023
2023 article
Defining the relevance of surgical margins. Part two: Strategies to improve prediction of recurrence risk
Bray, J., Eward, W., & Breen, M. (2023, February 15). VETERINARY AND COMPARATIVE ONCOLOGY.
author keywords: genetics; pathology; small animal; surgical oncology; tumour biology
MeSH headings : Animals; Cats; Dogs; Margins of Excision; Neoplasm, Residual / pathology; Neoplasm, Residual / veterinary; Cat Diseases / surgery; Neoplasm Recurrence, Local / veterinary; Dog Diseases / surgery
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 13, 2023
2023 journal article
A science-based agenda for health-protective chemical assessments and decisions: overview and consensus statement
ENVIRONMENTAL HEALTH, 21(SUPPL 1).
author keywords: Chemicals; Conflicts of Interest; Environmental Health; Environmental Justice; EPA; Hazard Identification; Health Equity; Risk Assessment; TSCA
MeSH headings : Humans; Environmental Exposure / adverse effects; Environmental Exposure / prevention & control; Environmental Health; Environmental Pollutants / analysis; Public Health; Risk Assessment; Consensus Development Conferences as Topic
TL;DR:
Consensus recommendations for health-protective, scientific approaches to reduce harmful chemical exposures are developed, which can be applied to current US policies governing industrial chemicals and environmental pollutants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 6, 2023
2023 review
Advancing the science on chemical classes
[Review of ]. ENVIRONMENTAL HEALTH, 21(SUPPL 1).
author keywords: Chemical class; Regulation; Decision-making; Toxic chemicals; Risk assessment; Chemical grouping; Ortho-phthalates
MeSH headings : Humans; Hazardous Substances / toxicity; Risk Assessment / methods
TL;DR:
Evaluation of how classes of chemicals are defined and used identified commonalities and differences based on regulatory frameworks, risk assessments, and business strategies and identified that using a class-based approach could result in a more efficient process to reduce exposures to multiple hazardous chemicals and, ultimately, reduce health risks.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 6, 2023
2023 journal article
<i>Rickettsia amblyommatis</i> in Ticks: A Review of Distribution, Pathogenicity, and Diversity
Microorganisms.
TL;DR:
The goal of this review was to compile the known literature on R. amblyommatis, review what the authors know about its geographic distribution, tick vectors, and pathogenicity, assess relatedness between various international strains from ticks by phylogenetic analysis and draw conclusions regarding future research needed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: February 21, 2023
2023 journal article
Improved Darcian streambed measurements to quantify flux and mass discharge of volatile organic compounds from a contaminated aquifer to an urban stream
JOURNAL OF CONTAMINANT HYDROLOGY, 253.
author keywords: VOC; Contaminant flux; Groundwater; Stream
MeSH headings : Humans; Volatile Organic Compounds; Water Pollutants, Chemical / analysis; Benzene; Ecosystem; Groundwater; Vinyl Chloride; Water
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 20, 2023
2023 journal article
Removal and destruction of perfluoroalkyl ether carboxylic acids (PFECAs) in an anion exchange resin and electrochemical oxidation treatment train
WATER RESEARCH, 230.
MeSH headings : Ether; Anion Exchange Resins; Carboxylic Acids; Ethers; Fluorocarbons / analysis; Water Pollutants, Chemical / analysis
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 20, 2023
2023 journal article
Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst
JOURNAL OF IMMUNOTOXICOLOGY, 20(1).
author keywords: Innate immunity; neutrophils; per- and polyfluoroalkyl substances (PFAS); reactive oxygen species; zebrafish
MeSH headings : Animals; Humans; Zebrafish; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Fluorocarbons / toxicity; Alkanesulfonic Acids / toxicity; Environmental Pollutants
TL;DR:
This report is the first to demonstrate that these PFASs suppress neutrophil function and support the utility of employing zebrafish larvae and a human cell line as screening tools to identify chemicals that may suppress human immune function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 15, 2023
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