Works Published in 2015
Displaying works 141 - 154 of 154 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Tak1, Smad4 and Trim33 redundantly mediate TGF-beta 3 signaling during palate development
DEVELOPMENTAL BIOLOGY, 398(2), 231–241.
author keywords: TGF-beta 3 signaling; Palatogenesis; Tak1; Smad4; Trim33
MeSH headings : Animals; Apoptosis / genetics; Cell Fusion; Cell Proliferation; Crosses, Genetic; Embryo, Mammalian / metabolism; Enzyme Activation; Epithelial Cells / metabolism; Epithelium / metabolism; Female; Gene Deletion; Gene Expression Regulation, Developmental; MAP Kinase Kinase Kinases / metabolism; Male; Matrix Metalloproteinase 13 / metabolism; Mice, Knockout; Models, Biological; Mutation / genetics; Organ Specificity; Palate / abnormalities; Palate / embryology; Palate / enzymology; Palate / metabolism; Signal Transduction; Smad4 Protein / metabolism; Transcription Factors / metabolism; Transforming Growth Factor beta3 / metabolism
TL;DR:
The data reveal added complexity in TGF-β signaling during palatogenesis and demonstrate that functionally redundant pathways involving Smad4, Tak1 and Trim33 regulate palatal epithelial fusion.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Full- and pilot-scale GAC adsorption of organic micropollutants
WATER RESEARCH, 68, 238–248.
Contributors: A. Kennedy *, A. Reinert n, D. Knappe n, I. Ferrer * & R. Summers *
author keywords: Granular activated carbon; Trace organic contaminants; Drinking water treatment; Pesticides; Pharmaceuticals; Personal care products
MeSH headings : Adsorption; Charcoal / chemistry; Models, Theoretical; Particle Size; Water Pollutants, Chemical / chemistry; Water Purification / methods
TL;DR:
A regression model was developed with data from three waters to predict MP throughput in bed volumes to 10% breakthrough (BV10%) based on the influent dissolved organic carbon concentration and the MP pH-dependent octanol-water partition coefficient, polarizability, and molecular volume.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitis
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 246(1), 118–125.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle; Cephalosporins / therapeutic use; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Female; Mastitis, Bovine / drug therapy; Mastitis, Bovine / metabolism; Milk / chemistry
TL;DR:
Pharmacokinetics and elimination of flunixin and 5-hydroxy flunxin in milk differed between mastitic and healthy cows, resulting in violative residues, which may partially explain the high number of fl unixin residues reported in beef and dairy cattle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Toxicoproteomic analysis of pulmonary carbon nanotube exposure using LC-MS/MS
TOXICOLOGY, 329, 80–87.
author keywords: Carbon nanotube; Label-free proteomics; Pulmonary fibrosis; Toxicoproteomics
MeSH headings : Acute-Phase Proteins / genetics; Acute-Phase Proteins / metabolism; Animals; Bronchoalveolar Lavage Fluid / chemistry; Chromatography, Liquid; Complement C3 / genetics; Complement C3 / metabolism; Complement C4b / genetics; Complement C4b / metabolism; Complement C9 / genetics; Complement C9 / metabolism; Histones / genetics; Histones / metabolism; Lactoferrin / genetics; Lactoferrin / metabolism; Lipocalin-2; Lipocalins / genetics; Lipocalins / metabolism; Lung / drug effects; Lung / metabolism; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Oncogene Proteins / genetics; Oncogene Proteins / metabolism; Peroxidase / genetics; Peroxidase / metabolism; Proteome / metabolism; Pulmonary Surfactant-Associated Protein B / genetics; Pulmonary Surfactant-Associated Protein B / metabolism; Tandem Mass Spectrometry; Toxicity Tests
TL;DR:
The protein secretion profile in lung bronchoalveolar lavage fluid from mice exposed to non-functionalized multi-walled carbon nanotubes or MWCNTs functionalized by nanoscale Al2O3 coatings formed using atomic layer deposition (ALD) was compared.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
The Comparative Toxicogenomics Database's 10th year anniversary: update 2015
NUCLEIC ACIDS RESEARCH, 43(D1), D914–D920.
MeSH headings : Databases, Chemical / history; Disease / etiology; Disease / genetics; Genomics / history; History, 21st Century; Internet; Phenotype; Toxicogenetics / history
TL;DR:
The prototype database originally described in its first report has transformed into a sophisticated resource used actively today to help scientists develop and test hypotheses about the etiologies of environmentally influenced diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Skin absorption of six performance amines used in metalworking fluids
JOURNAL OF APPLIED TOXICOLOGY, 35(5), 520–528.
author keywords: skin absorption; metalworking fluids; flow-through diffusion cell; ethanolamines; biocide
MeSH headings : Amines / pharmacokinetics; Animals; Cyclohexylamines / pharmacokinetics; Diphenylamine / pharmacokinetics; Disinfectants / pharmacokinetics; Ethanolamine / pharmacokinetics; Ethanolamines / pharmacokinetics; Gas Chromatography-Mass Spectrometry; Linear Models; Metallurgy; Permeability; Skin Absorption / drug effects; Swine
TL;DR:
To determine the absorption of six amines used as corrosion inhibitors and biocides in MWFs, porcine skin flow‐through diffusion cell experiments were conducted and results should help MWF industries choose safer additives for their formulations to protect the health of metalworkers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
SOURCES OF ENDOCRINE-DISRUPTING COMPOUNDS IN NORTH CAROLINA WATERWAYS: A GEOGRAPHIC INFORMATION SYSTEMS APPROACH
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 34(2), 437–445.
author keywords: Ecotoxicology; Endocrine disrupting compound; Estrogenicity; Geographic information system prediction; Surface water
MeSH headings : Endocrine Disruptors / analysis; Estradiol / analysis; Estrogens / analysis; Geographic Information Systems; Geography; Least-Squares Analysis; Models, Theoretical; North Carolina; Water Pollutants, Chemical / analysis
TL;DR:
The results suggested that water 17β-estradiol was reflective of GIS predictions, confirming the relevance of landscape-level influences on water quality and validating the GIS approach to characterize such relationships.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease
Environment International, 75, 144–150.
author keywords: Personal protective equipment; Parkinson's disease; Pesticides; Neurodegenerative diseases; Movement disorders
MeSH headings : Adult; Aged; Aged, 80 and over; Agriculture; Case-Control Studies; Female; Gloves, Protective / statistics & numerical data; Habits; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / prevention & control; Occupational Health; Paraquat; Parkinson Disease / epidemiology; Parkinson Disease / etiology; Permethrin; Pesticides; Risk; Rotenone; Surveys and Questionnaires; Trifluralin; Workplace
TL;DR:
Although sample size was limited in the FAME study, protective glove use and hygiene practices appeared to be important modifiers of the association between pesticides and PD and may reduce risk of PD associated with certain pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Neutralization of Mitochondrial Superoxide by Superoxide Dismutase 2 Promotes Bacterial Clearance and Regulates Phagocyte Numbers in Zebrafish
INFECTION AND IMMUNITY, 83(1), 430–440.
MeSH headings : Animals; Immunity, Innate; Leukocyte Count; Macrophages / enzymology; Macrophages / immunology; Mitochondria / enzymology; Mitochondria / metabolism; Pseudomonas aeruginosa / immunology; Superoxide Dismutase / metabolism; Superoxides / metabolism; Zebrafish
TL;DR:
The roles of SOD2 and mitochondrial ROS regulation in the zebrafish innate immune response to P. aeruginosa infection are described and the use of mitochondrion-targeted ROS scavengers as potential adjuvant therapies during severe infections is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Investing in prospective cohorts for etiologic study of occupational exposures
American Journal of Industrial Medicine, 58(2), 113–122.
author keywords: prospective cohorts; agricultural exposures; occupational epidemiology
MeSH headings : Agricultural Workers' Diseases / etiology; Epidemiologic Research Design; Humans; Occupational Exposure / analysis; Occupational Medicine; Prospective Studies
TL;DR:
Experience using this design to study agricultural workers to identify conditions that might foster use of prospective cohorts to study other occupational settings to investigate high priority, occupational exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Farm Characteristics, Allergy Symptoms, and Risk of Non-Hodgkin Lymphoid Neoplasms in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 24(3), 587–594.
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Agricultural Workers' Diseases / immunology; Cohort Studies; Farmers / statistics & numerical data; Female; Humans; Hypersensitivity / epidemiology; Hypersensitivity / etiology; Hypersensitivity / immunology; Lymphoma, Non-Hodgkin / epidemiology; Lymphoma, Non-Hodgkin / etiology; Lymphoma, Non-Hodgkin / immunology; Male; Middle Aged; North Carolina / epidemiology; Prospective Studies; Risk Factors
TL;DR:
Both the reduced risk of NHL among those with allergy symptoms and specific farm exposures in adulthood, and the increased risk among those who grew up on a farm suggest that the host immune response to agricultural allergens may influence NHL development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma
Nature Communications, 6.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Estrogen alters the profile of the transcriptome in river snail Bellamya aeruginosa
ECOTOXICOLOGY, 24(2), 330–338.
author keywords: Bellamya aeruginosa; Transcriptome; 454 sequencing; GO; Estrogen
MeSH headings : Animals; Estradiol / toxicity; Estrogens / toxicity; Molecular Sequence Data; Snails / drug effects; Snails / genetics; Transcriptome / drug effects; Water Pollutants, Chemical / toxicity
TL;DR:
Significant differences were found in gene expression in both liver and testicular tissues between control and E2-exposed organisms, which will help in understanding the molecular mechanisms of the response to physiological stress in the river snail exposed to estrogen.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Estimation of time-varying mortality rates using continuous models for Daphnia magna
APPLIED MATHEMATICS LETTERS, 44, 12–16.
author keywords: Structured population model; Leslie matrix model; Sinko-Streifer model; Daphnia magna; Time-dependent mortality rate
TL;DR:
It is found that a continuous differential equation model with a time-varying mortality rate was the most accurate model for describing the authors' experimental D. magna survival data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
