Works Published in 2022
Displaying works 21 - 40 of 82 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2022 article
Loss of Linker Histone H1 in the Maternal Genome Influences DEMETER-Mediated Demethylation and Affects the Endosperm DNA Methylation Landscape
Hsieh, T.-F., Han, Q., Hung, Y.-H., Zhang, C., Bartels, A., Rea, M., … Xiao, W. (2022, October 20).
doi.org (repository)
Source: ORCID
Added: October 21, 2022
2022 journal article
Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 626, 205–210.
author keywords: BTBR; Ob/ob; Type-2 diabetes; Flavanol; Insulin; Beta cell
MeSH headings : Animals; Cacao; Diabetes Mellitus, Type 2 / drug therapy; Female; Humans; Hyperglycemia; Hyperinsulinism; Male; Mice; Obesity; Pilot Projects; Plant Extracts / pharmacology; Plant Extracts / therapeutic use
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 17, 2022
2022 journal article
Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 109.
author keywords: Cocoa; sex differences; roasting; fermentation; obesity; inflammation
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use; Body Weight; Cacao; Chocolate; Diet, High-Fat / adverse effects; Disease Models, Animal; Food Ingredients; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Polyphenols / pharmacology
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 11, 2022
2022 journal article
Spatial Genomic Resource Reveals Molecular Insights into Key Bioactive-Metabolite Biosynthesis in Endangered <i>Angelica glauca</i> Edgew
International Journal of Molecular Sciences, 23(19), 11064.
Contributors: R. Seth* , R. Seth, R. Seth & R. Seth
Ed(s): R. Seth*
author keywords: Angelica glauca; transcriptome; specialized metabolites; phthalide; ferulic acid
MeSH headings : Angelica / genetics; Carotenoids / metabolism; Cinnamates / metabolism; Coumaric Acids; Flavonoids / metabolism; Gene Expression Profiling; Gene Expression Regulation, Plant; Genomics; Limonene; Methyltransferases / metabolism; Mixed Function Oxygenases / genetics; Molecular Sequence Annotation; NADP / metabolism; Oxidoreductases / metabolism; Phenylalanine / metabolism; Phenylalanine Ammonia-Lyase / metabolism; Plant Breeding; Plant Roots / genetics; Plant Roots / metabolism; Polyketides / metabolism; S-Adenosylmethionine / metabolism; Transcriptome
TL;DR:
The first comprehensive genomic resource with an array of candidate genes of the key metabolic pathways can be potentially utilized for the targeted upscaling of aromatic and pharmaceutically important bioactive metabolites.
(via Semantic Scholar)
Source: ORCID
Added: October 8, 2022
2022 journal article
Genome-wide identification and characterization of functionally relevant microsatellite markers from transcription factor genes of Tea (Camellia sinensis (L.) O. Kuntze)
Scientific Reports, 12(1).
Contributors: R. Seth*
MeSH headings : Camellia sinensis / genetics; Camellia sinensis / metabolism; Gene Expression Regulation, Plant; Gene Regulatory Networks; Genes, Plant; Genetic Variation; Genome, Plant; Microsatellite Repeats; Plant Proteins / genetics; Plant Proteins / metabolism; Protein Interaction Maps; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
Successful deployment of markers for genetic diversity characterization of 135 popular tea cultivars and segregation in bi-parental population suggests their wider utility in high-throughput genotyping studies in tea.
(via Semantic Scholar)
Source: ORCID
Added: October 8, 2022
2022 journal article
An Integrative Transcriptional Network Revealed Spatial Molecular Interplay Underlying Alantolactone and Inulin Biosynthesis in <i>Inula racemosa</i> Hook f.
International Journal of Molecular Sciences, 23(19), 11213.
Contributors: R. Seth* , R. Seth, R. Seth, R. Seth, R. Seth & R. Seth
Ed(s): R. Seth*
author keywords: alantolactones; Germacrene A; Inula racemosa; inulin; interactome; transcriptome; sesquiterpene lactones
MeSH headings : Anti-Infective Agents / metabolism; Carbohydrate Metabolism; Diterpenes / chemistry; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Regulatory Networks; Gibberellins / metabolism; Inula / chemistry; Inulin / metabolism; Lactones; Phytochemicals / analysis; Plant Breeding; Plant Roots / metabolism; Sesquiterpenes, Eudesmane; Terpenes / metabolism; Transcriptome
TL;DR:
The findings comprehensively demonstrate the source-sink transcriptional regulation of alantolactone and inulin biosynthesis, which can be further extended for upscaling the targeted specialized metabolites.
(via Semantic Scholar)
Source: ORCID
Added: October 8, 2022
2022 journal article
Sonoprocessing is an effective strategy to encapsulate fisetin into Saccharomyces cerevisiae cells
Applied Microbiology and Biotechnology.
author keywords: Food biotechnology; Yeast-based carriers; Lipophilic compounds; Ultrasound technology
MeSH headings : Saccharomyces cerevisiae / metabolism; Flavonols / metabolism; Freeze Drying; Antioxidants / metabolism; Cell Count
TL;DR:
This work proved that fully filled biocapsules were produced through sonoprocessing, and their morphology was influenced by the acoustic energy and drying process, paving the way for developing innovative yeast-based delivery systems for lipophilic compounds such as fisetin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: October 8, 2022
2022 review
Personalized nutrition: A review of genotype-based nutritional supplementation
[Review of ]. FRONTIERS IN NUTRITION, 9.
author keywords: personalized nutrition; nutritional supplementation; nutrient; genotype; single nucleotide polymorphisms; nutrigenetics
TL;DR:
Already literatures linking critical genetic variants to the nutrient and the ways in which these variants influence the outcomes of certain nutritional supplementations are reviewed, paving the way for the smooth transition of conventional generic approach to genotype-based personalized nutrition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 3, 2022
2022 journal article
Dissecting the genetic basis of bioactive metabolites and fruit quality traits in blueberries (Vaccinium corymbosum L.)
FRONTIERS IN PLANT SCIENCE, 13.
author keywords: blueberry; anthocyanin; acylation; glycosylation; QTL mapping; candidate genes; fruit quality; chlorogenic acid
TL;DR:
The study provides the first insights into the genetic basis controlling anthocyanins accumulation and composition, chlorogenic acid and fruit quality traits, and establishes a framework to advance genetic studies and molecular breeding for anthcyanins in blueberry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: September 26, 2022
2022 article
Six-month intervention with wild blueberries improved speed of processing in mild cognitive decline: a double-blind, placebo-controlled, randomized clinical trial
Cheatham, C. L., Canipelll, L. G., Millsap, G., Stegall, J. M., Chai, S. C., Sheppard, K. W., & Lila, M. A. (2022, September 8). NUTRITIONAL NEUROSCIENCE, Vol. 9.
author keywords: aging; CANTAB; event-related potentials; flavonoids; mild cognitive decline; speed of processing; polyphenols; wild blueberries
TL;DR:
Consumption of wild blueberries for six months improves cognitive aging sequelae by improving the speed of information processing in older adults by restoring speed of processing to the level of the reference group.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: September 19, 2022
2022 article
Autopolyploid inheritance and a heterozygous reciprocal translocation shape chromosome genetic behavior in tetraploid blueberry (Vaccinium corymbosum)
Mengist, M. F., Bostan, H., De Paola, D., Teresi, S. J., Platts, A. E., Cremona, G., … Iorizzo, M. (2022, September 3). NEW PHYTOLOGIST, Vol. 9.
author keywords: autopolyploid; blueberry (Vaccinium corymbosum L; ); centromeric repeat; chromosomal translocation; chromosome structure; phased genome; polyploid genetic behavior
MeSH headings : Tetraploidy; Blueberry Plants / genetics; Inheritance Patterns; Polyploidy; Chromosomes
TL;DR:
A new high‐quality, phased, chromosome‐scale genome of a diploid blueberry, clone W85 is described, which will facilitate new genetic and comparative genomic studies in Vaccinium and the development of genomic assisted selection strategy for this crop.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: September 19, 2022
2022 journal article
Ultrasound-assisted encapsulation of curcumin and fisetin into Saccharomyces cerevisiae cells: a multistage batch process protocol
Letters in Applied Microbiology.
author keywords: antioxidant activity; bioprocess; food biotechnology; lipophilic compounds; yeast-based carriers
MeSH headings : Curcumin / pharmacology; Saccharomyces cerevisiae; Antioxidants / pharmacology; Flavonols
TL;DR:
The antioxidant activity of produced biocapsules was positively correlated with the bioactive‐loaded content of yeasts when ultrasound treatment was applied and brought new and creative perspectives for ultrasound technology in the food industry.
(via Semantic Scholar)
Source: ORCID
Added: September 13, 2022
2022 review
Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health
[Review of ]. FRONTIERS IN NUTRITION, 9.
author keywords: phytonutrients; gut microbiota; metabolism; health outcomes; bioavailability
TL;DR:
The mechanisms by which phytonutrients and gut microbiota play roles in health are uncovered, and the interrelationships between phytonUTrients and Gut microbiota were summarized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 12, 2022
2022 journal article
Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation
REDOX BIOLOGY, 56.
Contributors: F. Ferrara*, V. Cordone *, A. Pecorelli* , M. Benedusi *, E. Pambianchi*, A. Guiotto*, A. Vallese* , F. Cervellati *, G. Valacchi*
author keywords: Inflammasomes; OxInflammation; Proteasome; UBR2; N-end rule pathway
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Air Pollutants; Apoptosis Regulatory Proteins / genetics; Catalase / metabolism; Cytokines / metabolism; Environmental Pollutants; Humans; Hydrogen Peroxide / metabolism; Inflammasomes / metabolism; NLR Proteins / metabolism; Oxidation-Reduction; Ozone / metabolism; Particulate Matter; Reactive Oxygen Species / metabolism; Ubiquitin-Protein Ligases / metabolism; Ubiquitination
TL;DR:
It is reported for the first time that O3, one of the most toxic pollutants, activates the NLRP1 inflammasome in human keratinocytes via oxidative stress mediators as hydrogen peroxide (H2O2) and 4-hydroxy-nonenal (4HNE).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 12, 2022
2022 review
Ultraviolet Light Protection: Is It Really Enough?
[Review of ]. ANTIOXIDANTS, 11(8).
author keywords: skin aging; ultraviolet light; solar radiation; pollution; reactive oxygen species; oxidative stress; antioxidants; chelators
TL;DR:
An updated, more comprehensive approach to environmental or atmospheric aging protection should include sun protective measures, broad spectrum sunscreens, antioxidants, chelating agents, and DNA repair enzymes.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: September 6, 2022
2022 journal article
Dimethyl Fumarate-Loaded Transethosomes: A Formulative Study and Preliminary Ex Vivo and In Vivo Evaluation
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(15).
author keywords: dimethyl fumarate; cryogenic transmission electron microscopy; wound healing; transethosomes; transdermal delivery
MeSH headings : Administration, Cutaneous; Dimethyl Fumarate / pharmacology; Drug Delivery Systems / methods; Humans; Liposomes / chemistry; Phosphatidylcholines / metabolism; Skin / metabolism; Skin Absorption
TL;DR:
The selected transethosome gel, loading 25 mg/mL dimethyl fumarate, was not irritant after cutaneous application under occlusion, suggesting its possible suitability in the treatment of wounds caused by diabetes mellitus or peripheral vascular diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 29, 2022
2022 journal article
There and back again; historical perspective and future directions for Vaccinium breeding and research studies
HORTICULTURE RESEARCH, 9.
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 1, 2022
2022 journal article
Coordinated transcriptional regulation of the carotenoid biosynthesis contributes to fruit lycopene content in high-lycopene tomato genotypes
HORTICULTURE RESEARCH, 9.
TL;DR:
This is the first systematic investigation of the role of the complete pathway genes in regulating fruit lycopene biosynthesis across many HLYs, and enables tomato breeding and gene editing for increased fruit Lycopene content.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 1, 2022
2022 review
Oxidative-Stress-Sensitive microRNAs in UV-Promoted Development of Melanoma
[Review of ]. CANCERS, 14(13).
author keywords: skin cancer; sunlight; redox imbalance; miRNome; mutations; epigenome
TL;DR:
Current evidence suggests a complex interaction between UV-promoted deregulation of redox-sensitive miRNAs and known signal-transduction pathways underlying malignant transformation of melanocytes to melanoma, which could have relevant implications for future therapeutic approaches aimed at counteracting UV-induced redox and miRNome imbalances.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2022
2022 article
Phenolic-rich beverages reduce bacterial TMA formation in an ex vivo-in vitro colonic fermentation model
Iglesias-Carres, L., Racine, K. C., & Neilson, A. P. (2022, July 11). FOOD & FUNCTION.
MeSH headings : Atherosclerosis / metabolism; Bacteria / metabolism; Beverages; Chlorogenic Acid; Choline / metabolism; Coffee; Fermentation; Humans; Methylamines / metabolism
TL;DR:
Regular cocoa and coffee consumption could be a nutritional strategy able to reduce TMAO levels, and fractionating digested bioactive beverages determined that those fractions rich in chlorogenic acid were the most bioactive.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 26, 2022
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