Works Published in 2000
Displaying works 101 - 119 of 119 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2000 journal article
Primary immunodeficiencies of horses
VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 16(1), 105-+.
MeSH headings : Agammaglobulinemia / veterinary; Animals; Horse Diseases / immunology; Horses; Immunoglobulin M / deficiency; Immunologic Deficiency Syndromes / veterinary; Severe Combined Immunodeficiency / immunology; Severe Combined Immunodeficiency / veterinary
TL;DR:
The central theme is to encourage clinicians to ask, "I wonder if this horse has an underlying primary immunodeficiency disorder?" when caring for horses suffering from chronic and recurring infections and responding poorly to standard therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Glutamine metabolism stimulates intestinal cell MAPKs by a cAMP-inhibitable, Raf-independent mechanism
GASTROENTEROLOGY, 118(1), 90–100.
MeSH headings : Cell Division / drug effects; Cell Line; Cyclic AMP / analogs & derivatives; Cyclic AMP / metabolism; Cyclic AMP / pharmacology; DNA / biosynthesis; DNA / drug effects; Enzyme Activation / drug effects; Enzyme Inhibitors / pharmacology; Epidermal Growth Factor / metabolism; Epidermal Growth Factor / pharmacology; Flavonoids / pharmacology; Glutamine / metabolism; Glutamine / pharmacology; Intestinal Mucosa / metabolism; Intestines / cytology; MAP Kinase Signaling System / drug effects; Mitogen-Activated Protein Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinases / metabolism; Oxygen Consumption / drug effects; Thionucleotides / pharmacology; Thymidine / metabolism
TL;DR:
In vitro kinase assays showed that glutamine signaling requires an intact ERK (extracellular signal-related kinase) pathway in unstarved cells and increased levels of intracellular cAMP inhibit ERKs but only partially reduce glutamine-stimulated proliferation in enterocytes adapted to low glutamine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Evaluation of ciprofloxacin as a representative of veterinary fluoroquinolones in susceptibility testing
Journal of Clinical Microbiology, 38(4), 1636–1637.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
The effects of Tempol on ferritin synthesis and Fe metabolism in lens epithelial cells
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1497(1), 51–60.
author keywords: ferritin; Fe metabolism; lens; cataract; lens epithelial cell; tempol; oxidative damage; peroxide; free radical
MeSH headings : Animals; Antioxidants / pharmacology; Cyclic N-Oxides / pharmacology; Dogs; Dose-Response Relationship, Drug; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Female; Ferritins / biosynthesis; Ferritins / drug effects; Iron / metabolism; Lens, Crystalline / cytology; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism; Male; Spin Labels; Time Factors; tert-Butylhydroperoxide / pharmacology
TL;DR:
The redistribution of Fe within the cell after 20 h of Tempol treatment appears to render the cells more vulnerable to oxidative stress, likely due to its effects on Fe metabolism, perhaps by reducing the availability of Fe for incorporation into ferritin and Fe-dependent enzymes as well as enlarging a low molecular weight pool of Fe which may be capable of catalyzing damaging free radical reactions.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Serum oxytetracycline concentrations in African elephant (Loxodonta africana) calves after long-acting formulation injection
Journal of Zoo and Wildlife Medicine, 31(1), 41–46.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro - Signaling pathways controlling surface and gene expression
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(6), 685–692.
MeSH headings : Antibodies, Monoclonal; Bronchi / cytology; Cell Line; Epithelial Cells / enzymology; Epithelial Cells / immunology; Flow Cytometry; Gene Expression / immunology; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1 / genetics; Intercellular Adhesion Molecule-1 / immunology; L-Lactate Dehydrogenase / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Promoter Regions, Genetic / physiology; RNA Processing, Post-Transcriptional / physiology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Respiratory Mucosa / cytology; Signal Transduction / immunology; Tumor Necrosis Factor-alpha / pharmacology
TL;DR:
The intracellular signaling pathway leading to enhanced expression appeared to involve activation of a phospholipase C that hydrolyzes phosphatidylcholine (PC-PLC) becaus...
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway
MOLECULAR AND CELLULAR BIOLOGY, 20(2), 672–683.
MeSH headings : Animals; Binding Sites; Carrier Proteins; Cell Cycle Proteins; Cell Transformation, Neoplastic / pathology; Cyclin D1 / antagonists & inhibitors; Cyclin D1 / genetics; Cyclin D1 / metabolism; DNA-Binding Proteins / metabolism; E2F Transcription Factors; E2F1 Transcription Factor; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mammary Glands, Animal / metabolism; Mammary Glands, Animal / pathology; Mice; Mice, Nude; Mice, Transgenic; Mitogen-Activated Protein Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinases / metabolism; Monomeric GTP-Binding Proteins / genetics; Monomeric GTP-Binding Proteins / metabolism; Mutation / genetics; Promoter Regions, Genetic / genetics; Proto-Oncogene Mas; RNA, Antisense / genetics; RNA, Antisense / physiology; Receptor, ErbB-2 / antagonists & inhibitors; Receptor, ErbB-2 / genetics; Receptor, ErbB-2 / metabolism; Retinoblastoma-Binding Protein 1; Sp1 Transcription Factor / metabolism; Sp3 Transcription Factor; Transcription Factor DP1; Transcription Factors / metabolism; Transcriptional Activation; Tumor Cells, Cultured
TL;DR:
It is demonstrated that E2F-1 mediates a Neu-signaling cascade tocyclin D1 and identify cyclin D 1 as a critical downstream target of neu-induced transformation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Antifungal dermatologic agents: Azoles and allylamines
Compendium on Continuing Education for the Practicing Veterinarian, 22(6), 548–559.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 46(1), 179–185.
author keywords: tumors; hyperthermia blood how; pO(2); pH; thermal dose
MeSH headings : Animals; Combined Modality Therapy; Dogs; Female; Hydrogen-Ion Concentration; Hyperthermia, Induced / methods; Male; Oxygen / metabolism; Partial Pressure; Sarcoma, Experimental / blood supply; Sarcoma, Experimental / metabolism; Sarcoma, Experimental / radiotherapy; Sarcoma, Experimental / therapy; Soft Tissue Neoplasms / blood supply; Soft Tissue Neoplasms / metabolism; Soft Tissue Neoplasms / radiotherapy; Soft Tissue Neoplasms / therapy
TL;DR:
This study suggests that hyperthermia has biphasic effects on tumor physiologic parameters, and suggests that the thermal threshold for vascular damage is higher in spontaneous tumors than in more rapidly growing rodent tumors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Histologic and immunohistochemical characterization of lens capsular plaques in dogs with cataracts
AMERICAN JOURNAL OF VETERINARY RESEARCH, 61(2), 139–143.
MeSH headings : Actins / analysis; Animals; Cataract / pathology; Cataract / veterinary; Cataract Extraction / veterinary; Dog Diseases / pathology; Dogs; Fibronectins / analysis; Histocytochemistry; Humans; Immunohistochemistry / methods; Lens, Crystalline / pathology; Lens, Crystalline / ultrastructure; Tenascin / analysis; Transforming Growth Factor beta / analysis
TL;DR:
Canine lens capsular plaques are histologically and immunohistochemically similar to posterior capsule opacification and subcapsular cataracts in humans, which suggests that the canine condition, like the human conditions, is associated with fibrous metaplasia of lens epithelial cells.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2000 article
Granulomatous disease associated with Bartonella infection in 2 dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 37–42.
author keywords: canine; infectious; lymphadenopathy; pathology
TL;DR:
This is the 1st report of granulomatous disease in dogs associated with Bartonella infection, and an 11-year-old mixed-breed dog was referred for evaluation of a 6-week history of serous nasal discharge.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2000 journal article
A mass in the spinal column of a dog
VETERINARY CLINICAL PATHOLOGY, 29(3), 87–89.
author keywords: cytology; dog; nephroblastoma; spinal cord
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
The relationship between intracellular and extracellular pH in spontaneous canine tumors
Clinical Cancer Research, 6(6), 2501–2505.
Source: NC State University Libraries
Added: August 6, 2018
2000 personal communication
Untitled - Reply
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Traditional antifungal dermatologic agents
Compendium on Continuing Education for the Practicing Veterinarian, 22(5), 461.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Messenger ribonucleic acids for MAC25 and connective tissue growth factor (CTGF) are inversely regulated during folliculogenesis and early luteogenesis
ENDOCRINOLOGY, 141(7), 2648–2657.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2000 journal article
Hepatic abscesses in three horses
JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 216(6), 882-+.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Female; Horse Diseases / drug therapy; Horse Diseases / pathology; Horse Diseases / surgery; Horses; Liver Abscess / drug therapy; Liver Abscess / surgery; Liver Abscess / veterinary; Male
TL;DR:
All horses were euthanatized because of a worsening condition and poor prognosis, and a variety of bacteria were isolated from these abscesses, including Staphylococus aureus and Bacteroides fragilis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Glucosamine and chondroitin sulfate
Compendium on Continuing Education for the Practicing Veterinarian, 22(5), 454.
Source: NC State University Libraries
Added: August 6, 2018
2000 article
Effect of surgical technique on in vitro posterior capsule opacification
Davidson, M. G., Morgan, D. K., & McGahan, M. C. (2000, October). JOURNAL OF CATARACT AND REFRACTIVE SURGERY, Vol. 26, pp. 1550–1554.
MeSH headings : Animals; Cataract / etiology; Cataract / pathology; Cataract / prevention & control; Cell Count; Cells, Cultured; Culture Media, Serum-Free; Dogs; Lens Capsule, Crystalline / pathology; Lens Capsule, Crystalline / surgery; Phacoemulsification / methods; Postoperative Complications / etiology; Postoperative Complications / pathology; Postoperative Complications / prevention & control
TL;DR:
Phacoemulsification with and without anterior and equatorial capsular vacuuming led to less initial LEC density in the capsular bag than ECCE, however, because cell proliferation rates among the 3 groups were only marginally affected, near 100% removal of LEC at the time of cataract extraction may be necessary to prevent PCO.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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