Works Published in 2009
Displaying works 601 - 620 of 632 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 journal article
Neonatal agonism of ERα masculinizes serotonergic (5-HT) projections to the female rat ventromedial nucleus of the hypothalamus (VMN) but does not impair lordosis
Behavioural Brain Research, 196(2), 317–322.
author keywords: Estrogen; Development; Hypothalamus; Serotonin; Sex differences; Estrogen receptor; DPN; PPT
MeSH headings : Animals; Animals, Newborn / physiology; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogen Receptor alpha / agonists; Estrogen Receptor alpha / physiology; Estrogen Receptor beta / agonists; Female; Male; Neural Pathways / physiology; Nitriles / pharmacology; Phenols / pharmacology; Propionates / pharmacology; Pyrazoles / pharmacology; Rats; Serotonin / physiology; Sex Characteristics; Sexual Behavior, Animal / physiology; Ventromedial Hypothalamic Nucleus / physiology
TL;DR:
Observations show that postnatal estrogens increase the density of 5-HT projections to the VMNvl via an ERalpha dependent mechanism, but that this increased inhibitory input is not sufficient to suppress the lordosis response.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2009 article
MORPHOLOGY OF THE CAUDAL FOSSA IN CAVALIER KING CHARLES SPANIELS
VETERINARY RADIOLOGY & ULTRASOUND, Vol. 50, pp. 37–46.
author keywords: chiari-like; occipital hypoplasia; syringomyelia; MRI
MeSH headings : Animals; Arnold-Chiari Malformation / diagnosis; Arnold-Chiari Malformation / genetics; Arnold-Chiari Malformation / pathology; Arnold-Chiari Malformation / veterinary; Atlanto-Axial Joint / pathology; Atlanto-Occipital Joint / pathology; Breeding; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Foramen Magnum / abnormalities; Foramen Magnum / anatomy & histology; Magnetic Resonance Imaging / methods; Magnetic Resonance Imaging / veterinary; Male; Syndrome; Syringomyelia / diagnosis; Syringomyelia / genetics; Syringomyelia / pathology; Syringomyelia / veterinary
TL;DR:
While several factors are associated with the presence of neurologic signs, occipital hypoplasia appears to be the most important factor.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination
GENES AND IMMUNITY, 10(2), 112–119.
author keywords: smallpox; Random Forests; integrated analysis; genetic; proteomic; interactions
MeSH headings : Biomarkers / blood; Cytokines / blood; Cytokines / genetics; Decision Making, Computer-Assisted; Female; Humans; Inflammation / blood; Inflammation / chemically induced; Inflammation / genetics; Intercellular Adhesion Molecule-1 / blood; Intercellular Adhesion Molecule-1 / genetics; Male; Models, Biological; Polymorphism, Single Nucleotide; Proteomics / methods; Smallpox Vaccine / administration & dosage; Smallpox Vaccine / adverse effects; Vaccination
TL;DR:
This study built a comprehensive model of AE development that includes the cytokines intercellular adhesion molecule-1 (ICAM-1 or CD54), interleukin-10 (IL-10), and colony stimulating factor-3 (CSF-3 or G-CSF) and a genetic polymorphism in the cyokine gene interleUKin-4 (IL4).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Infrared digital imaging of the equine anterior segment
Veterinary Ophthalmology, 12(2), 125–131.
author keywords: anterior segment; corneal disease; digital infrared photography; equine; melanoma; equine ophthalmology
MeSH headings : Animals; Eye / anatomy & histology; Eye Diseases / diagnosis; Eye Diseases / veterinary; Horse Diseases / diagnosis; Horses / anatomy & histology; Infrared Rays; Ophthalmology / instrumentation; Ophthalmology / methods; Photography / instrumentation; Photography / methods; Photography / veterinary
TL;DR:
In the equine eye, advantages of infrared digital photography include increased contrast of anterior segment images, identification and monitoring of pigmentary changes, and increased visualization of the anterior segment through a cloudy or edematous cornea.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2009 journal article
Identification of microRNA in the developing chick immune organs
IMMUNOGENETICS, 61(3), 231–240.
author keywords: MicroRNA; Molecular biology; Spleen; Bursa; Chicken embryos
MeSH headings : Animals; Base Sequence; Bursa of Fabricius / immunology; Bursa of Fabricius / metabolism; Chick Embryo / immunology; Gene Expression Regulation; Gene Library; MicroRNAs / chemistry; MicroRNAs / genetics; MicroRNAs / metabolism; Molecular Sequence Data; Specific Pathogen-Free Organisms; Spleen / immunology; Spleen / metabolism
TL;DR:
Overall, the results show that many of the identified miRNAs display dynamic expression patterns, suggesting that these mi RNAs play diverse roles in the immune system.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 review
Genome-scale analyses of health-promoting bacteria: probiogenomics
[Review of ]. NATURE REVIEWS MICROBIOLOGY, 7(1), 61–U77.
MeSH headings : Bifidobacterium / genetics; Bifidobacterium / metabolism; Genomics; Humans; Lactobacillus / genetics; Lactobacillus / metabolism; Probiotics
TL;DR:
The application of probiogenomics in the elucidation of the molecular basis of probiosis is discussed using the well-recognized model probiotic bacteria genera Bifidobacterium and Lactobacillus as examples.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Generation and characterization of novel canine malignant mast cell line CL1
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 127(1-2), 114–124.
author keywords: Mast cell tumor; KIT; Cell line
MeSH headings : Animals; Base Sequence; Cell Degranulation; Cell Line, Tumor; DNA Primers / genetics; DNA, Neoplasm / genetics; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study; Immunophenotyping; Mast Cells / immunology; Mast Cells / pathology; Mast Cells / physiology; Mastocytosis, Systemic / genetics; Mastocytosis, Systemic / immunology; Mastocytosis, Systemic / pathology; Mastocytosis, Systemic / veterinary; Proto-Oncogene Proteins c-kit / genetics; Proto-Oncogene Proteins c-kit / metabolism
TL;DR:
A novel mast cell line is generated from an 11-year-old spayed female Labrador retriever diagnosed with systemic mastocytosis and neoplastic effusion that possesses phenotypic and functional properties similar to those found in canine BMCMCs, and will likely be a useful tool to study mast cell biology, factors regulating transformation of mast cells, cytogenetic abnormalities in mast cell tumors, and novel preclinical therapies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Form, function and phylogenetics of NITRs in bony fish
Developmental & Comparative Immunology, 33(2), 135–144.
author keywords: Teleost; Innate immunity; Natural killer receptors; ITIM; ITSM; DAP12; CD8; KIR
MeSH headings : Animals; DNA, Complementary / genetics; Fishes / genetics; Fishes / immunology; Humans; Immunoglobulins / immunology; Ligands; Phylogeny; Receptors, Immunologic / chemistry; Receptors, Immunologic / genetics; Receptors, Immunologic / immunology
TL;DR:
An analysis of all published NITRs demonstrates the conserved nature of multiple residues within the NITR Ig domains permitting the identification of NITr ESTs from salmon, cod, halibut, lake whitefish and stickleback species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Energy- and Hole-Transfer Dynamics in Oxidized Porphyrin Dyads
JOURNAL OF PHYSICAL CHEMISTRY B, 113(1), 54–63.
TL;DR:
A detailed understanding is provided of the mechanism and dynamics of quenching of excited porphyrins by nearby oxidized sites, as well as the dynamics of ground-state hole transfer between nonequivalent poiryrins (Zn and Fb).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Different Modes of Binding of Mono-, Di-, and Trihalogenated Phenols to the Hemoglobin Dehaloperoxidase from Amphitrite ornata
BIOCHEMISTRY, 48(10), 2164–2172.
MeSH headings : Animals; Binding Sites / physiology; Catalysis; Catalytic Domain / physiology; Heme / chemistry; Hemoglobins / chemistry; Hemoglobins / genetics; Hemoglobins / metabolism; Hydrocarbons, Halogenated / chemistry; Hydrocarbons, Halogenated / metabolism; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Peroxidases / chemistry; Peroxidases / genetics; Peroxidases / metabolism; Phenols / chemistry; Phenols / metabolism; Polychaeta / enzymology; Polychaeta / genetics; Potassium Cyanide / chemistry; Protein Binding / physiology; Protein Conformation; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Substrate Specificity
TL;DR:
The most soluble trihalogenated phenol acts as a highly soluble structural analogue to the native substrate 2,4,6-tribromophenol, and to improve the understanding of substrate binding, the most soluble substrate analogues are compared.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Comparison of capsular opacification and refractive status after placement of three different intraocular lens implants following phacoemulsification and aspiration of cataracts in dogs
Veterinary Ophthalmology, 12(1), 13–21.
author keywords: design; dog; intraocular lens; material; posterior capsular opacification; refractive error
MeSH headings : Acrylic Resins; Animals; Cataract / veterinary; Cataract Extraction / instrumentation; Cataract Extraction / methods; Cataract Extraction / veterinary; Dog Diseases / surgery; Dogs; Female; Lens Implantation, Intraocular / instrumentation; Lens Implantation, Intraocular / methods; Lens Implantation, Intraocular / veterinary; Male; Phacoemulsification / veterinary; Polymethyl Methacrylate; Prosthesis Design; Random Allocation; Treatment Outcome
TL;DR:
Square edged foldable acrylic IOLs show a predisposition towards generating slightly less PCO than round edged PMMA I OLs in the early postoperative period, however, both acrylic Iols had greater persistent hyperopia than the PMMAIOLs.
(via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2009 journal article
ClC-2 is required for rapid restoration of epithelial tight junctions in ischemic-injured murine jejunum
Experimental Cell Research, 315(1), 110–118.
Contributors: P. Nighot n, A. Moeser n, K. Ryan n, T. Ghashghaei n & A. Blikslager n
author keywords: Tight junction; Intestinal permeability; Ischemia; ClC-2
MeSH headings : Animals; CLC-2 Chloride Channels; Cell Membrane / metabolism; Chloride Channels / deficiency; Chloride Channels / metabolism; Epithelium / metabolism; Epithelium / pathology; Epithelium / ultrastructure; Fluorescent Antibody Technique; Immunoprecipitation; Ischemia / metabolism; Ischemia / physiopathology; Jejunum / blood supply; Jejunum / pathology; Jejunum / ultrastructure; Mannitol / metabolism; Membrane Proteins / metabolism; Mice; Mice, Knockout; Occludin; Protein Transport; Tight Junctions / metabolism; Tight Junctions / ultrastructure; Wound Healing
TL;DR:
A pivotal role is demonstrated in recovery of the intestinal epithelium barrier by anchoring assembly of tight junctions following ischemic injury in ClC-2(-/-) mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Robe of Cyclin D1 as a Mediator of c-Met- and beta-Catenin-Induced Hepatocarcinogenesis
CANCER RESEARCH, 69(1), 253–261.
MeSH headings : Animals; Cell Transformation, Neoplastic / genetics; Cell Transformation, Neoplastic / metabolism; Cyclin D1 / biosynthesis; Cyclin D1 / genetics; Cyclin D2; Cyclins / biosynthesis; Cyclins / genetics; Disease Models, Animal; Female; Humans; Liver Neoplasms, Experimental / genetics; Liver Neoplasms, Experimental / metabolism; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-met / biosynthesis; Proto-Oncogene Proteins c-met / genetics; Transfection; Up-Regulation; beta Catenin / biosynthesis; beta Catenin / genetics
TL;DR:
The results suggest that CCND1 functions as a mediator of beta-catenin during HCC pathogenesis, although other molecules may be required to fully propagate beta-Catenin signaling.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Distal histidine conformational flexibility in dehaloperoxidase from Amphitrite ornata
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 65, 34–40.
MeSH headings : Animals; Crystallization; Crystallography, X-Ray; Heme Oxygenase (Decyclizing) / chemistry; Heme Oxygenase (Decyclizing) / metabolism; Hemoglobins / chemistry; Hemoglobins / metabolism; Histidine / chemistry; Histidine / metabolism; Iodobenzenes / chemistry; Iodobenzenes / metabolism; Peroxidases / chemistry; Peroxidases / metabolism; Polychaeta / enzymology; Protein Binding; Protein Conformation; Solvents
TL;DR:
It is reported that the distal histidine, His55, exhibits conformational flexibility in the deoxy form and is consequently observed in two solvent-exposed conformations more than 9.5 A away from the heme, analogous to the open conformation of sperm whale myoglobin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Whole-genome scan for quantitative trait loci associated with birth weight, gestation length and passive immune transfer in a Holstein x Jersey crossbred population
ANIMAL GENETICS, 40(1), 27–34.
Contributors: C. Maltecca* , K. Weigel *, H. Khatib *, M. Cowan & A. Bagnato *
author keywords: calf traits; dairy cattle; Holstein; Jersey; quantitative trait loci
MeSH headings : Animals; Birth Weight / genetics; Cattle / genetics; Cattle / immunology; Crosses, Genetic; Dairying; Female; Genome-Wide Association Study; Male; Pregnancy; Quantitative Trait Loci
TL;DR:
Results from a daughter design genome-scan study aiming to identify quantitative trait loci associated with birth weight, direct gestation length and passive immune transfer in a backcross (Holstein x Jersey) x Holstein population are reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2009 journal article
Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts
JOURNAL OF CELL SCIENCE, 122(3), 313–323.
author keywords: Cell migration; Phosphoinositide 3-kinase; Integrin; Fibronectin; Adhesion
MeSH headings : Actins / antagonists & inhibitors; Actins / metabolism; Animals; Chemotaxis / physiology; Cytochalasin D / pharmacology; Cytoskeleton / metabolism; Fibroblasts / cytology; Fibroblasts / metabolism; Fibroblasts / physiology; Focal Adhesion Protein-Tyrosine Kinases / metabolism; Mice; Phosphatidylinositol 3-Kinases / metabolism; Platelet-Derived Growth Factor / metabolism; Pseudopodia / metabolism; Receptors, Platelet-Derived Growth Factor / metabolism; Signal Transduction / physiology
TL;DR:
Live-cell imaging using total internal reflection fluorescence (TIRF) microscopy revealed that, in the absence of soluble cues, 3′-phosphoinositides are enriched in a localized and dynamic fashion during active spreading and random migration of mouse fibroblasts on adhesive surfaces.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Organic trace minerals and 25-hydroxycholecalciferol affect performance characteristics, leg abnormalities, and biomechanical properties of leg bones of turkeys
POULTRY SCIENCE, 88(1), 118–131.
author keywords: turkey; organic trace mineral; 25-hydroxycholecalciferol; leg problem; bone
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Biomechanical Phenomena; Bone Development / drug effects; Bone and Bones / drug effects; Calcifediol / pharmacology; Diet; Dietary Supplements; Hindlimb / pathology; Lameness, Animal / drug therapy; Male; Trace Elements / pharmacology; Turkeys / growth & development; Walking / physiology
TL;DR:
Dietary MIN supplementation may improve feed conversion of turkeys, likely by decreasing leg problems and maximum shear stress at failure of femoral bones in a torsion assay was increased by supplementation with both MIN and HyD together.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Nonparametric autocovariance estimation from censored time series by Gaussian imputation
JOURNAL OF NONPARAMETRIC STATISTICS, 21(2), 241–259.
Contributors: J. Park *, M. Genton * & S. Ghosh n
author keywords: censoring; Gibbs sampling; imputation; nonparametric estimation; truncated multivariate normal distribution
TL;DR:
A Gaussian imputation method to estimate an autocovariance structure via nonparametric estimation of the autocvariance function in order to address both censoring and incorrect model specification is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2009 journal article
Isolation of Candidatus Bartonella melophagi from Human Blood
Emerging Infectious Diseases, 15(1), 66–68.
MeSH headings : Aged; Animals; Bacteremia / microbiology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / complications; Bartonella Infections / microbiology; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Blood / microbiology; Citrate (si)-Synthase / genetics; Culture Media; DNA, Ribosomal Spacer / analysis; Female; Humans; Middle Aged; RNA Polymerase II / genetics; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 23S / genetics; Sheep / microbiology
TL;DR:
Candidatus Bartonella melophagi was isolated by blood culture from 2 women, 1 of whom was co-infected with B. henselae, and partial 16S rRNA, RNA polymerase B, and citrate synthase genes and 16S–23S internal transcribed spacer sequences indicated that human isolates were similar to Candidatus B.melophagi.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Expression of Proinflammatory Cytokines by Human Mesenchymal Stem Cells in Response to Cyclic Tensile Strain
JOURNAL OF CELLULAR PHYSIOLOGY, 219(1), 77–83.
MeSH headings : Animals; Bone Marrow Cells / cytology; Bone Marrow Cells / physiology; Cells, Cultured; Cytokines / metabolism; Humans; Interleukin-1beta / metabolism; Interleukin-6 / metabolism; Interleukin-8 / metabolism; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Stress, Mechanical; Stress, Physiological; Tensile Strength; Tumor Necrosis Factor-alpha / metabolism; Young Adult
TL;DR:
IL‐6 and IL‐8 expressions by hMSCs were induced by cyclic tensile strain and osteogenic differentiating media, indicating that IL‐ 6 andIL‐8 may be functioning as autocrine signals during osteogenic differentiation of h MSCs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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