Kannapolis Research

Works Published in 2023

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Displaying works 21 - 40 of 91 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2023 article

OxInflammation in Alzheimer's disease

Cervellati, C., Zuliani, G., & Valacchi, G. (2023, December). NEURAL REGENERATION RESEARCH, Vol. 18, pp. 2709–2710.

By: C. Cervellati, G. Zuliani & G. Valacchi* 

TL;DR: Or pro-inflammatory cytokines, such as reactive microglia, dysfunctional mitochondria, amyloid-β aggregates, are involved in inflammation and cell reprograming. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 23, 2023

2023 article

Population genomics identifies genetic signatures of carrot domestication and improvement and uncovers the origin of high-carotenoid orange carrots

Coe, K., Bostan, H., Rolling, W., Turner-Hissong, S., Macko-Podgorni, A., Senalik, D., … Iorizzo, M. (2023, September 28). NATURE PLANTS, Vol. 9.

By: K. Coe n, H. Bostan n, W. Rolling *, S. Turner-Hissong, A. Macko-Podgorni *, D. Senalik *, S. Liu  n, R. Seth n  ...

TL;DR: It is demonstrated that carrot was domesticated during the Early Middle Ages in the region spanning western Asia to central Asia, and orange carrot was selected during the Renaissance period, probably in western Europe, through the selection of three recessive genes that increased the provitamin A carotenoid (α- and β-carotene) content. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 16, 2023

2023 journal article

Lipid-Based Nanosystems for the Topical Application of Ferulic Acid: A Comparative Study

PHARMACEUTICS, 15(7).

By: M. Sguizzato *, F. Ferrara*, M. Drechsler *, A. Baldisserotto *, L. Montesi*, S. Manfredini *, G. Valacchi* , R. Cortesi *

author keywords: ferulic acid; antioxidant molecules; transferosomes; vesicles; monoolein aqueous dispersions; topical application; cryo-TEM
TL;DR: Results indicate that the LBNs produced with poloxamer 188 in their composition create a multilamellar system that effectively controls the release of the drug, and it is found that the type of non-ionic surfactant can impact the drug release rate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: October 10, 2023

2023 article

UDP-glucosyltransferase HvUGT13248 confers type II resistance to Fusarium graminearum in barley

Bethke, G., Huang, Y., Hensel, G., Heinen, S., Liu, C., Wyant, S. R., … Muehlbauer, G. J. (2023, August 23). PLANT PHYSIOLOGY.

By: G. Bethke *, Y. Huang *, G. Hensel *, S. Heinen *, C. Liu *, S. Wyant *, X. Li*, M. Quin* ...

TL;DR: Taken together, the data reveal that UGT13248 confers type II resistance to FHB in barley via conjugation of DON to D3G. (via Semantic Scholar)
Source: Web Of Science
Added: September 18, 2023

2023 journal article

Spray drying to produce novel phytochemical-rich ingredients from juice and pomace of American elderberry

FOOD BIOSCIENCE, 55.

By: K. Ravichandran *, E. Silva n, M. Moncada n, P. Perkins-Veazie n, M. Lila n , C. Greenlief *, A. Thomas*, R. Hoskin  n, K. Krishnaswamy *

author keywords: Sambucus; Dietary supplement; Repurposing; Powder ingredients; Bioaccessibility; Phytochemicals
Sources: Web Of Science, NC State University Libraries
Added: September 18, 2023

2023 journal article

Modulation of Cutaneous Carotenoid Content via Ozone Exposure

COSMETICS, 10(4).

By: F. Cervellati *, M. Benedusi *, A. Mastaloudis, V. Nagliati* & G. Valacchi n 

author keywords: skin barrier; carotenoids; ozone exposure; Raman spectroscopy; statistics
TL;DR: Evaluating the variations in carotenoid content present in human skin prior to and after O3 exposure in 141 human subjects confirmed their importance in the maintenance of cutaneous redox homeostasis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 11, 2023

2023 journal article

Dietary Prebiotic Oligosaccharides and Arachidonate Alter the Fecal Microbiota and Mucosal Lipid Composition of Suckling Pigs

JOURNAL OF NUTRITION, 153(8), 2249–2262.

By: B. Eudy  n, J. Odle n , . Lin  n, C. Maltecca n , K. Walter n, N. McNulty*, V. Fellner n , S. Jacobi *

author keywords: microbiota; ARA; prebiotics; oligosaccharides; infant formula
TL;DR: Although dietary ARA did not alter the microbiota, prebiotic supplementation during the first 22 days of life increased the ARA content of the colonic mucosa, which may support intestinal development and epithelial repair. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: September 11, 2023

2023 review

Carotenoids in Health as Studied by Omics-Related Endpoints

[Review of ]. ADVANCES IN NUTRITION, 14(6), 1538–1578.

By: T. Bohn *, E. Balbuena n, H. Ulus n, M. Iddir*, G. Wang n, N. Crook n , A. Eroglu n 

author keywords: health; inflammation; beta-carotene; lycopene; lutein; oxidative stress; metabolites; LC-MS-MS; exposome; transcription factors; cellular compartments; body tissues
TL;DR: This review highlights the use of omics technologies to assess health-related effects of carotenoids in mammalian organisms and models and (multi)omics–related techniques, especially transcriptomics, proteomics, lipidomics, and metabolomics, measured in a variety of biospecimens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 9, 2023

2023 journal article

The role of potassium current in the pulmonary response to environmental oxidative stress

Archives of Biochemistry and Biophysics, 2, 109534.

By: R. Canella *, M. Benedusi *, A. Vallese* , A. Pecorelli *, A. Guiotto*, F. Ferrara *, G. Rispoli *, F. Cervellati *, G. Valacchi *

Contributors: R. Canella *, M. Benedusi *, A. Vallese* , A. Pecorelli *, A. Guiotto*, F. Ferrara *, G. Rispoli *, F. Cervellati *, G. Valacchi *

TL;DR: The data suggest that O3 is able to inhibit potassium current by targeting BK channel, and can contribute to identify the biomolecular pathway induced by O3 allowing a possible pharmacological intervention against oxidative stress damage in lung tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: September 6, 2023

2023 journal article

Ox-inflammasome involvement in neuroinflammation

FREE RADICAL BIOLOGY AND MEDICINE, 207, 161–177.

By: A. Vallese* , V. Cordone *, A. Pecorelli*  & G. Valacchi n 

TL;DR: The current knowledge on the involvement of inflammasome in the main neuropathologies is provided, emphasizing the importance to further clarify the role of oxidative stress in its activation including therole of mitochondria in inflammaome-induced neuroinflammation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: September 5, 2023

2023 journal article

A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study

AMERICAN JOURNAL OF CLINICAL NUTRITION, 118(2), 369–381.

By: D. Vauzour *, A. Scholey *, D. White *, N. Cohen *, A. Cassidy *, R. Gillings*, M. Irvine*, C. Kay n  ...

author keywords: omega-3; polyphenols; flavonoids; mild cognitive impairment; subjective cognitive impairment; aging; cognition
TL;DR: The results suggest that cosupplementation with ω-3 PUFAs and cocoa flavanols for 12 mo does not improve cognitive outcomes in those with cognitive impairment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 5, 2023

2023 journal article

Moderate consumption of freeze-dried blueberry powder increased net bone calcium retention compared with no treatment in healthy postmenopausal women: a randomized crossover trial

AMERICAN JOURNAL OF CLINICAL NUTRITION, 118(2), 382–390.

By: J. Hodges *, M. Maiz*, S. Cao *, P. Lachcik*, M. Peacock *, G. McCabe *, L. McCabe*, D. Cladis * ...

author keywords: bone; blueberries; calcium; osteoporosis; polyphenols; postmenopausal
TL;DR: Moderate consumption of blueberries may be an effective strategy to attenuate bone loss in healthy postmenopausal women and no significant relationships were found between bone resorption biomarkers, 25-hydroxyvitamin D, and interventions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 5, 2023

2023 journal article

Ultrasound-assisted polyphenol extraction of acerola and jambolan pomaces: comparison of extraction protocols, kinetic modeling, and life cycle assessment

CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 191.

By: E. Silva*, A. Nunes * & R. Hoskin  n

author keywords: revalorization; fruit waste; environmentally friendly; bioactive compounds
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 5, 2023

2023 journal article

In vitro evidences of the globe artichoke antioxidant, cardioprotective and neuroprotective effects

JOURNAL OF FUNCTIONAL FOODS, 107.

By: L. Iglesias-Carres  n, A. Bruno*, I. 'Antuono *, V. Linsalata *, A. Cardinali * & A. Neilson n 

author keywords: Artichoke; Polyphenols; Antiaging; TMAO; Neuroprotective
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 28, 2023

2023 journal article

Blueberry intake elevates post-exercise anti-inflammatory oxylipins: a randomized trial

SCIENTIFIC REPORTS, 13(1).

By: D. Nieman*, C. Sakaguchi *, A. Omar*, K. Davis*, C. Shaffner*, R. Strauch n, M. Lila n , Q. Zhang *

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 journal article

Identification of bromelain subfamily proteases encoded in the pineapple genome

SCIENTIFIC REPORTS, 13(1).

By: A. Yow n , H. Bostan n, R. Young*, G. Valacchi n , N. Gillitt, P. Perkins-Veazie n, Q. Xiang n , M. Iorizzo n

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 journal article

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health. METABOLITES, 13(7).

By: E. Krueger *, L. Griffin n, J. Beales*, T. Lloyd*, N. Brown *, W. Elison *, C. Kay n , A. Neilson n , J. Tessem *

author keywords: gut microbiome; phytochemicals; flavanol metabolites; glucose sensitivity; responder analysis; personalized nutrition
TL;DR: It is concluded that metabolite bioactivity on GSIS capacity is less related to flavanol supplementation or antibiotic treatment and may be more associated with the unique microbiome or metabolome of each animal, suggesting flavanol metabolite activities are individualized and point to the need for personalized nutrition practices. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 14, 2023

2023 journal article

Functional characterization of DcMYB11, an R2R3 MYB associated with the purple pigmentation of carrot petiole

PLANTA, 258(3).

By: V. D'Amelia *, J. Curaba n , M. Abid n, S. Esposito *, P. Cavagnaro *, D. Carputo*, M. Iorizzo n

author keywords: Anthocyanins; Carrot petiole; Daucus carota; Regulatory sequences; Transcription factor
TL;DR: This study provides novel insight into the molecular mechanisms controlling anthocyanin accumulation in carrot and expanded the knowledge on the cis-regulatory sequences in plants by identifying three different alleles which may explain differences in petiole pigmentation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 14, 2023

2023 journal article

Effect of Microwave and Ultrasound-Assisted Extraction on the Phytochemical and In Vitro Biological Properties of Willow (Salix alba) Bark Aqueous and Ethanolic Extracts

PLANTS-BASEL, 12(13).

By: R. Aleman *, J. Marcia *, C. Duque-Soto *, J. Lozano-Sanchez *, I. Montero-Fernandez *, J. Ruano, R. Hoskin  n, M. Moncada n

author keywords: phytochemistry; antioxidant; anti-inflammatory; medicinal plants; acetylcholinesterase inhibition
TL;DR: Findings suggest that willow (Salix alba) bark extract obtained via ethanolic microwave-assisted extraction is a phytochemical-rich resource with in vitro, anti-inflammatory, and AchE inhibitory properties and, therefore, potential multiple medicinal end-uses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 7, 2023

2023 journal article

Compositional analysis of phytochemicals and polysaccharides from Senegalese plant ingredients: Adansonia digitata (baobab), Moringa oleifera (moringa) and Hibsicus sabdariffa (hibiscus)

NFS JOURNAL, 32.

By: H. Debelo n, C. Fiecke *, A. Terekhov*, B. Reuhs*, B. Hamaker * & M. Ferruzzi n

author keywords: Nutrition profile; Phenolic compounds; Monosaccharide composition; Moringa; Hibiscus; Baobab
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 7, 2023

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