Works Published in 2011
Displaying works 461 - 480 of 685 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
Investigation of breed and sex effects on cytochrome P450 gene expression in cattle liver
RESEARCH IN VETERINARY SCIENCE, 90(2), 235–237.
Contributors: M. Ashwell n, R. Fry n, J. Spears n, . A.T. O'Nan n & C. Maltecca n
author keywords: Cytochrome P450; Cattle; Gene expression; Liver
MeSH headings : Animals; Cattle / genetics; Cattle / metabolism; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Female; Gene Expression Regulation, Enzymologic / genetics; Gene Expression Regulation, Enzymologic / physiology; Liver / enzymology; Male; Sex Characteristics
TL;DR:
Breed and/or sex of an animal may need to be considered before administering a dose of a xenobiotic due to the potential for harmful drug residues in foodstuffs as well as improper treatment of disease conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2011 journal article
Inflammatory polyps of the nasal turbinates of cats: an argument for designation as feline mesenchymal nasal hamartoma
JOURNAL OF FELINE MEDICINE AND SURGERY, 13(4), 213–219.
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / pathology; Cat Diseases / surgery; Cats; Diagnosis, Differential; Female; Hamartoma / diagnosis; Hamartoma / pathology; Hamartoma / surgery; Hamartoma / veterinary; Male; Nasal Polyps / diagnosis; Nasal Polyps / pathology; Nasal Polyps / surgery; Nasal Polyps / veterinary; Nose Diseases / diagnosis; Nose Diseases / pathology; Nose Diseases / surgery; Nose Diseases / veterinary; Terminology as Topic; Treatment Outcome
TL;DR:
The terminology ‘feline mesenchymal nasal hamartoma’ provides a more accurate description of the disease currently termed IPNT, and has the added advantage of being consistent with its human counterpart.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Inference on treatment effects from a randomized clinical trial in the presence of premature treatment discontinuation: the SYNERGY trial
BIOSTATISTICS, 12(2), 258–269.
author keywords: Dynamic treatment regime; Inverse probability weighting; Potential outcomes; Proportional hazards model
MeSH headings : Acute Coronary Syndrome / drug therapy; Algorithms; Computer Simulation; Endpoint Determination; Enoxaparin / administration & dosage; Enoxaparin / adverse effects; Enoxaparin / therapeutic use; Hemorrhage / etiology; Heparin / administration & dosage; Heparin / adverse effects; Heparin / therapeutic use; Humans; Intention to Treat Analysis; Models, Statistical; Monte Carlo Method; Mortality; Multicenter Studies as Topic; Probability; Proportional Hazards Models; Randomized Controlled Trials as Topic / methods; Survival Analysis; Treatment Outcome; Withholding Treatment / statistics & numerical data
TL;DR:
The Superior Yield of the New Strategy of Enoxaparin, Revascularization, and GlYcoprotein IIb/IIIa inhibitors (SYNERGY) was a randomized, open-label, multicenter clinical trial comparing 2 anticoagulant drugs on the basis of time-to-event endpoints.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Increasing proteome coverage with offline RP HPLC coupled to online RP nanoLC-MS
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 879(9-10), 610–614.
author keywords: RP HPLC; Fractionation methods; Proteomics; Mass spectrometry
MeSH headings : Chromatography, High Pressure Liquid / methods; Chromatography, Reverse-Phase / methods; Mass Spectrometry / methods; Nanotechnology; Peptide Fragments / analysis; Peptide Fragments / metabolism; Proteome / analysis; Proteome / metabolism; Proteomics / methods; Saccharomyces cerevisiae Proteins / analysis; Saccharomyces cerevisiae Proteins / metabolism
TL;DR:
The success of performing offline reversed phase high pressure liquid chromatography (HPLC) fractionation on a C18 2.0 mm×150 mm column at the peptide level with microliter per minute flow rates prior to online nano-flow reversed phase liquid Chromatography mass spectrometry (nanoLC-MS) using the well-studied fungus Saccharomyces cerevisiae is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Improving Proteome Coverage on a LTQ-Orbitrap Using Design of Experiments
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22(4), 773–783.
author keywords: LTQ-Orbitrap XL MS/MS instrument parameters; Design of experiments; Fractional-factorial design; Saccharomyces cerevisiae; Proteomics
MeSH headings : Peptide Fragments; Peptide Mapping; Proteome / chemistry; Proteomics / methods; Research Design; Saccharomyces cerevisiae Proteins / chemistry; Tandem Mass Spectrometry / methods; Temperature
TL;DR:
The DOE approach represents a time- and cost-effective method for empirically optimizing MS-based proteomics workflows including sample preparation, LC conditions, and multiple instrument platforms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Identification of alternative splice variants in Aspergillus flavus through comparison of multiple tandem MS search algorithms
BMC Genomics, 12.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Hydrophobic Derivatization of N-linked Glycans for Increased Ion Abundance in Electrospray Ionization Mass Spectrometry
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22(8), 1309–1317.
author keywords: Hydrophobic Derivatization; HILIC; nanoESI; N-Linked Glycans; Hydrazone Formation
MeSH headings : Blood Proteins / chemistry; Carbohydrate Sequence; Chromatography, Liquid; Glycoproteins / chemistry; Humans; Hydrazines / chemistry; Hydrophobic and Hydrophilic Interactions; Polysaccharides / chemistry; Small Molecule Libraries; Spectrometry, Mass, Electrospray Ionization / methods; Tandem Mass Spectrometry
TL;DR:
The results of this study will direct the future synthesis of hydrophobic reagents for glycan analysis using the correlation between hydrophobicity and theoretical non-polar surface area calculation to facilitate the development of an optimum tag for gly can derivatization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Highly Stable Binding Proteins Derived from the Hyperthermophilic Sso7d Scaffold
JOURNAL OF MOLECULAR BIOLOGY, 409(4), 601–616.
author keywords: hyperthermophilic protein scaffolds; yeast surface display; protein engineering; stability; alternate scaffold
MeSH headings : Amino Acid Sequence; Animals; Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Chickens; DNA Mutational Analysis; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Fluorescein / chemistry; Fluorescein / metabolism; Immunoglobulins / chemistry; Immunoglobulins / metabolism; Mice; Molecular Sequence Data; Muramidase / chemistry; Muramidase / metabolism; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Denaturation; Streptavidin / chemistry; Streptavidin / metabolism; Sulfolobus solfataricus / chemistry; beta Catenin / chemistry; beta Catenin / metabolism
TL;DR:
It is shown that highly stable binding proteins for a wide spectrum of targets can be generated through mutagenesis of the Sso7d protein from the hyperthermophilic archaeon Sulfolobus solfataricus, and that S so7d-derived binding proteins could discriminate between closely related immunoglobulins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
H-ras Consensus Sequence and Mutations in Primary Hepatocellular Carcinomas of Lemurs and Lorises
VETERINARY PATHOLOGY, 48(4), 868–874.
author keywords: liver; molecular biology; oncology; primate; zoo; hepatocellular carcinoma
MeSH headings : Animals; Carcinoma, Hepatocellular / genetics; Carcinoma, Hepatocellular / pathology; Carcinoma, Hepatocellular / veterinary; Consensus Sequence; Female; Gene Expression Regulation, Neoplastic; Genes, ras / genetics; Lemur; Liver Neoplasms / genetics; Liver Neoplasms / pathology; Liver Neoplasms / veterinary; Lorisidae; Male; Mutation; Primate Diseases / genetics; Primate Diseases / pathology
TL;DR:
The authors have determined a consensus sequence for exons 1 and 2 of H-ras from captive lemurs and lorises and evaluated samples of nonneoplastic liver and hepatocellular carcinomas from affected animals for mutations in these exons, and have determined that it is identical to that of human H-ra and differs only slightly from the chimpanzee sequence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Gene-drive into insect populations with age and spatial structure: a theoretical assessment
EVOLUTIONARY APPLICATIONS, 4(3), 415–428.
author keywords: age and spatial structure; engineered underdominance; gene drive; release threshold; theoretical assessment
TL;DR:
This study demonstrates that to determine the best method of spatial release, and the total number of engineered insects that must be released, it is important to take into account the age and sex of the released insects and spatial structure of the population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2011 journal article
Facile Self-Assembly of Supramolecular Hexakisferrocenyl Triangles via Coordination-Driven Self-Assembly and Their Electrochemical Behavior
ORGANOMETALLICS, 30(13), 3637–3642.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Evolution of clinical, haematological and biochemical findings in young dogs naturally infected by vector-borne pathogens
Veterinary Microbiology, 149(1-2), 206–212.
author keywords: Vector-borne diseases; Clinical signs; Haematological alterations; Diagnosis
MeSH headings : Anaplasma / pathogenicity; Animals; Babesia / pathogenicity; Bartonella / pathogenicity; Coccidia / pathogenicity; Disease Vectors; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Ehrlichia canis / pathogenicity; Gram-Negative Bacterial Infections / drug therapy; Imidazoles / pharmacology; Longitudinal Studies; Male; Neonicotinoids; Nitro Compounds / pharmacology; Permethrin / pharmacology; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / drug therapy; Siphonaptera / microbiology; Thrombocytopenia; Ticks / microbiology
TL;DR:
This study emphasizes the clinical difficulties associated with assigning a specific clinical sign or haematological abnormality to a particular canine vector-borne disease and serially monitored naturally infected dogs throughout a 1-year follow-up period.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 personal communication
Evaluation of the agreement between allergen-specific intradermal or IgE serological tests and a point-of-care immunodot assay in dogs with atopic dermatitis
Olivry, T., & Paps, J. (2011, June).
MeSH headings : Allergens / immunology; Animals; Dermatitis, Atopic / blood; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Immunoblotting / methods; Immunoblotting / veterinary; Immunoglobulin E / blood; Intradermal Tests / veterinary; Predictive Value of Tests; Serologic Tests / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Evaluation of Location-Specific Predictions by a Detailed Simulation Model of Aedes aegypti Populations
PLoS ONE, 6(7), e22701.
Ed(s): E. Ooi
MeSH headings : Aedes; Animals; Argentina; Female; Models, Theoretical; Population Dynamics; Stochastic Processes; Time Factors
TL;DR:
The results show that Skeeter Buster replicates specific population dynamics and spatial structure of Ae.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2011 journal article
Engineering of red cells of Arabidopsis thaliana and comparative genome-wide gene expression analysis of red cells versus wild-type cells
PLANTA, 233(4), 787–805.
author keywords: Arabidopsis thaliana; Anthocyanin; Biosynthesis; Cyanin; Metabolic engineering; Microarray analysis
MeSH headings : Anthocyanins / chemistry; Anthocyanins / metabolism; Arabidopsis / cytology; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant / genetics; Genetic Engineering / methods; Genome, Plant / genetics; Pancreatitis-Associated Proteins; Principal Component Analysis; Spectrometry, Mass, Electrospray Ionization; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
It is suggested that the difference in gene expression profiles between the two cell lines likely results from cell types, the overexpression of PAP1, and the high metabolic flux toward anthocyanins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Encapsulation Efficiency and Micellar Structure of Solute-Carrying Block Copolymer Nanoparticles
MACROMOLECULES, 44(13), 5443–5451.
TL;DR:
As conditions become more conducive to micelle formation, a stronger energy barrier to solute insertion forms which in turn decreases the encapsulation efficiency of the system, explaining the results in the context of a model of drug insertion into micelles formulated by Kumar and Prud'homme.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Effect and Distribution of Contrast Medium after Injection into the Anterior Suprachoroidal Space in Ex Vivo Eyes
Investigative Opthalmology & Visual Science, 52(8), 5730.
MeSH headings : Age Factors; Animals; Anterior Chamber / diagnostic imaging; Anterior Chamber / metabolism; Choroid / diagnostic imaging; Choroid / metabolism; Contrast Media / pharmacokinetics; Dogs; Drug Delivery Systems; Imaging, Three-Dimensional; In Vitro Techniques; Injections, Intraocular / methods; Latex / pharmacokinetics; Microbubbles; Posterior Eye Segment / diagnostic imaging; Posterior Eye Segment / metabolism; Retina / diagnostic imaging; Retina / metabolism; Swine; Ultrasonography
TL;DR:
The authors' hypothesis that a single anterior SCS injection can reach the ocular posterior segment was supported and it is suggested that the SCS can expand, in a dose-dependent manner, to accommodate various volumes of fluid and that it is possible to image theSCS with ultrasound contrast.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2011 journal article
Durable antibacterial Ag/polyacrylonitrile (Ag/PAN) hybrid nanofibers prepared by atmospheric plasma treatment and electrospinning
EUROPEAN POLYMER JOURNAL, 47(7), 1402–1409.
author keywords: Atmospheric plasma; Electrospinning; Nanofibers; Ag nanoparticles; Antibacterial activity
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Detection of Clostridium difficile and Salmonella in Feral Swine Population in North Carolina
JOURNAL OF WILDLIFE DISEASES, 47(3), 774–776.
MeSH headings : Animals; Animals, Domestic; Animals, Wild; Anti-Bacterial Agents / pharmacology; Clostridioides difficile / drug effects; Clostridioides difficile / isolation & purification; Disease Reservoirs / veterinary; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous / drug therapy; Enterocolitis, Pseudomembranous / epidemiology; Enterocolitis, Pseudomembranous / transmission; Enterocolitis, Pseudomembranous / veterinary; Female; Male; North Carolina / epidemiology; Prevalence; Salmonella / drug effects; Salmonella / isolation & purification; Salmonella Infections, Animal / drug therapy; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / transmission; Sus scrofa / microbiology; Swine; Swine Diseases / drug therapy; Swine Diseases / epidemiology; Swine Diseases / transmission
TL;DR:
Seven and eight feral pigs tested positive for C. difficile and Salmonella, respectively, highlighting the importance of determining the epidemiology of these pathogens in feral pigs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Dehaloperoxidase-Hemoglobin from Amphitrite ornata Is Primarily a Monomer in Solution
JOURNAL OF PHYSICAL CHEMISTRY B, 115(14), 4266–4272.
MeSH headings : Animals; Crystallography, X-Ray; Dimerization; Hemoglobins / chemistry; Peroxidases / chemistry; Polychaeta / enzymology; Polychaeta / metabolism; Protein Conformation; Scattering, Small Angle; Solutions / chemistry; X-Ray Diffraction
TL;DR:
DHP A is primarily monomeric in solution, but with a detectable level of dimer (~10%), under all conditions studied up to a protein concentration of 3.0 mM, which is likely 10-100-fold lower than the K(d) for dimer formation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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