Works Published in 2020

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Displaying works 41 - 60 of 131 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

Veterinarians and impostor syndrome: an exploratory study

VETERINARY RECORD, 187(7).

By: L. Kogan*, R. Schoenfeld-Tacher n, P. Hellyer*, E. Grigg* & E. Kramer*

MeSH headings : Adult; Anxiety Disorders / epidemiology; Cross-Sectional Studies; Female; Humans; Internationality; Male; Middle Aged; Prevalence; Risk Factors; Self Concept; Veterinarians / psychology; Veterinarians / statistics & numerical data
TL;DR: Veterinarians in general have an alarmingly high prevalence of IS with young, female graduates practising in the UK and NZ at increased risk, and women, UK residents and new practitioners reported higher levels of impact in their professional life. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (OpenAlex)
Source: Web Of Science
Added: November 16, 2020

2020 review

The twists and turns of left-right asymmetric gut morphogenesis

[Review of ]. DEVELOPMENT, 147(19).

author keywords: Gut tube; Intestine; Laterality; Left-right asymmetry; Morphogenesis; Stomach
MeSH headings : Animals; Body Patterning / genetics; Body Patterning / physiology; Gastrointestinal Microbiome / genetics; Gastrointestinal Microbiome / physiology; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Developmental / physiology; Humans; Morphogenesis / genetics; Morphogenesis / physiology; Signal Transduction / genetics; Signal Transduction / physiology
TL;DR: New evidence is summarized challenging century-old ideas about the development of stomach and intestine laterality, challenging classical models of left-right asymmetric gut morphogenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: November 16, 2020

2020 personal communication

Expert Opinion on Verification of Antimicrobial Susceptibility Tests

Patel, J. B., Thomson, R. B., Alby, K., Babady, E., Culbreath, K., Galas, M. F., … Schuetz, A. N. (2020, November).

By: J. Patel*, R. Thomson*, K. Alby*, E. Babady*, K. Culbreath*, M. Galas*, S. Lockhart*, B. Lubbers* ...

author keywords: CLIA; antibiotic; antifungal susceptibility testing; antimicrobial; verification
MeSH headings : Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Anti-Infective Agents / pharmacology; Expert Testimony; Humans; Microbial Sensitivity Tests; Pseudomonas Infections / drug therapy
TL;DR: The Expert Panel on Microbiology would like to respond to the recent commentary by Kirby and colleagues voicing concerns related to verification of commercial antimicrobial susceptibility testing for new drugs that are introduced into the clinical laboratory. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 9, 2020

2020 journal article

Development of a Genome-Wide Oligonucleotide Microarray Platform for Detection of DNA Copy Number Aberrations in Feline Cancers

VETERINARY SCIENCES, 7(3).

By: R. Thomas n, J. Pontius*, L. Borst n & M. Breen n

author keywords: feline; cat; cancer; genomics; chromosome; comparative genomic hybridization (CGH)
TL;DR: A microarray platform that allows rapid and sensitive detection of DNA copy number aberrations in feline tumors using comparative genomic hybridization analysis is developed and shown to have diverse potential to incorporate domestic cat cancers into comparative and translational research efforts in molecular oncology. (via Semantic Scholar)
Source: Web Of Science
Added: November 9, 2020

2020 journal article

Pharmacokinetics of Ketoprofen in Nile Tilapia (Oreochromis niloticus) and Rainbow Trout (Oncorhynchus mykiss)

FRONTIERS IN VETERINARY SCIENCE, 7.

By: W. Greene*, N. Mylniczenko*, T. Storms*, C. Burns*, G. Lewbart n, L. Byrd*, M. Papich n

author keywords: ketoprofen; teleost; tilapia; rainbow trout; pharmacokinctics; non-steroidal anti-inflammatory drugs (NSAIDs); Oncorhynchus mykiss; Oreochromis niloticus
TL;DR: There were very high plasma concentrations of ketoprofen in trout and tilapia with no adverse effects observed, and future studies on the efficacy, frequency of dosing, analgesia, adverse effects, and route of administration are warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 9, 2020

2020 article

What is your diagnosis? Transtracheal wash in a horse

Mochizuki, H., Eaton, E., Breuhaus, B., & Stowe, D. M. (2020, December). VETERINARY CLINICAL PATHOLOGY, Vol. 49, pp. 675–677.

MeSH headings : Animals; Horses; Trachea
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 9, 2020

2020 journal article

Effect of Methadone or Hydromorphone on Cardiac Conductivity in Dogs Before and During Sevoflurane Anesthesia

FRONTIERS IN VETERINARY SCIENCE, 7.

author keywords: methadone; hydromorphone; sevoflurane; QT interval; ECG; dog
TL;DR: Both methadone and hydromorphone administration reduced HR and prolonged PR and QT intervals, with greater changes observed during sevoflurane anesthesia, and both drugs caused considerable QT interval prolongation into the proarrhythmogenic range, with Methadone causing greater prolongation. (via Semantic Scholar)
Source: Web Of Science
Added: October 26, 2020

2020 journal article

Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish

SCIENTIFIC REPORTS, 10(1).

MeSH headings : Adipose Tissue / metabolism; Adiposity / physiology; Animals; Diet; Growth Disorders / metabolism; Hyperplasia / etiology; Hyperplasia / physiopathology; Liver / metabolism; Obesity / metabolism; Obesity, Abdominal / complications; Vitamin D / metabolism; Vitamin D Deficiency / metabolism; Vitamin D Deficiency / physiopathology; Zebrafish / growth & development; Zebrafish / metabolism; Zebrafish Proteins / metabolism
TL;DR: Findings indicate that early developmental VDD impacts metabolic health by disrupting the balance between somatic growth and adipose accumulation, which is associated with hallmarks of dyslipidemia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: October 26, 2020

2020 journal article

Rapid stimulation of cellular Pi uptake by the inositol pyrophosphate InsP(8) induced by its photothermal release from lipid nanocarriers using a near infra-red light-emitting diode

CHEMICAL SCIENCE, 11(37), 10265–10278.

TL;DR: Thermosensitive liposomes were used to deliver inositol pyrophosphates into cultured cells and cargo release was induced within 5 min irradiation by a high power, near infra-red, light emitting diode. (via Semantic Scholar)
Source: Web Of Science
Added: October 19, 2020

2020 journal article

Derivation of stable embryonic stem cell-like, but transcriptionally heterogenous, induced pluripotent stem cells from non-permissive mouse strains

MAMMALIAN GENOME, 31(9-12), 263–286.

By: T. Garbutt n, K. Konganti*, T. Konneker n, A. Hillhouse*, D. Phelps n, A. Jones n, D. Aylor n, D. Threadgill*

MeSH headings : Animals; Biomarkers; Cell Differentiation; Cells, Cultured; Cellular Reprogramming / genetics; Embryonic Stem Cells / cytology; Embryonic Stem Cells / metabolism; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genetic Heterogeneity; Immunophenotyping; Induced Pluripotent Stem Cells / cytology; Induced Pluripotent Stem Cells / metabolism; Mice; Platelet Endothelial Cell Adhesion Molecule-1; Species Specificity; Transcriptome
TL;DR: Heterogeneity is a naturally occurring, necessary quality of stem cells that allows for the maintenance of pluripotency and this study is the first study to derive stable ESC-like stem cells from the non-permissive NOD/ShiLtJ and WSB/EiJ strains, enabling easier and broader research possibilities into pluripOTency for these and similar non-Permissive mouse strains and species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 19, 2020

2020 article

iDISCO Allows Complete Visualization and Analysis of Postnatal Enteric Nervous System Development in a Comparative Pig Model

Erwin, S., Touvron, M., Odle, J., Van Landeghem, L., Blikslager, A., & Ziegler, A. (2020, April). FASEB JOURNAL, Vol. 34.

Source: Web Of Science
Added: October 12, 2020

2020 personal communication

A novel motor-sparing locoregional nerve block technique for stifle surgery in dogs

Gingold, B. M. C., Milloway, M. C., & Morgan, M. J. (2020, September).

By: B. Gingold*, M. Milloway n & M. Morgan

MeSH headings : Animals; Bupivacaine; Dog Diseases / surgery; Dogs; Nerve Block / veterinary; Stifle / surgery
Source: Web Of Science
Added: October 12, 2020

2020 article

A Glial Cell Inhibitor Blocks Epithelial Barrier Repair in a Pig Model of Intestinal Ischemia

Sheridan, A., Pridgen, T., Odle, J., Van Landeghem, L., Blikslager, A., & Ziegler, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: A. Sheridan*, T. Pridgen*, J. Odle*, L. Van Landeghem*, A. Blikslager* & A. Ziegler*

TL;DR: It is hypothesized that EGC inhibition in juveniles will block epithelial barrier repair after ischemic injury mimicking the neonatal phenotype, and the development of glial‐epithelial crosstalk in barrier repair will ultimately guide novel clinical solutions to improve outcomes in neonatal patients affected by intestinal injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 12, 2020

2020 article

Effects of Oligosaccharide Supplementation on Intestinal Morphology and Enteric Glial Cell Marker Expression in a Neonatal Pig Model

Shapiro, L., Ziegler, A., Odle, J., Van Landeghem, L., & Blikslager, A. (2020, April). FASEB JOURNAL, Vol. 34.

By: L. Shapiro n, A. Ziegler n, J. Odle n, L. Van Landeghem n & A. Blikslager n

TL;DR: Test the effects of dietary oligosaccharides on postnatal changes in the EGC network and intestinal morphology in a neonatal pig model to find increased mucosal expression of EGC markers earlier in postnatal development in the high oligOSaccharide group, as well as histological changes consistent with enhanced rates of gut maturation in pigs fed a high oligosACcharide diet. (via Semantic Scholar)
Source: Web Of Science
Added: October 12, 2020

2020 journal article

Total injectable anesthesia of dogs and cats for remote location veterinary sterilization clinic

BMC VETERINARY RESEARCH, 16(1).

author keywords: sterilization; dog; cat; anesthesia; total injectable anesthesia
MeSH headings : Adrenergic alpha-2 Receptor Antagonists / administration & dosage; Anesthesia, Intravenous / veterinary; Anesthetics, Combined / administration & dosage; Animals; Cats / surgery; Dexmedetomidine / administration & dosage; Dogs / surgery; Ecuador; Female; Hydromorphone / administration & dosage; Imidazoles / administration & dosage; Ketamine / administration & dosage; Male; Meloxicam / administration & dosage; Orchiectomy / veterinary; Ovariectomy / veterinary; Pregnanediones
TL;DR: Total injectable anesthesia can be accomplished for remote location sterilization clinics with minimal morbidity. (via Semantic Scholar)
Source: Web Of Science
Added: October 5, 2020

2020 journal article

Cherenkov emissions for studying tumor changes during radiation therapy: An exploratory study in domesticated dogs with naturally-occurring cancer

PLOS ONE, 15(8).

By: A. Rickard*, H. Yoshikawa n, G. Palmer n, H. Liu*, M. Dewhirst n, M. Nolan n, X. Zhang

MeSH headings : Animals; Dogs; Image Processing, Computer-Assisted; Neoplasms / diagnostic imaging; Neoplasms / radiotherapy; Particle Accelerators; Pilot Projects; Prospective Studies; Radiotherapy Dosage; Tomography, X-Ray Computed; X-Rays
TL;DR: It is demonstrated that it is possible to obtain Cherenkov emissions from canine cancers within a fraction of radiotherapy, and lends credence to the goal of using this method during radiotherapy in human patients and client-owned pets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: September 21, 2020

2020 journal article

Computed tomography in two recumbencies aides in the identification of pulmonary bullae in dogs with spontaneous pneumothorax

VETERINARY RADIOLOGY & ULTRASOUND, 61(6), 641–648.

author keywords: bleb; bullous emphysema; diagnosis
MeSH headings : Animals; Dogs; Female; Male; Dog Diseases / diagnostic imaging; Dog Diseases / physiopathology; Lung Diseases / complications; Lung Diseases / diagnostic imaging; Lung Diseases / veterinary; Observer Variation; Pneumothorax / complications; Pneumothorax / diagnostic imaging; Pneumothorax / veterinary; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Supine Position; Tomography, X-Ray Computed / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 21, 2020

2020 journal article

The effect of combined carprofen and omeprazole administration on gastrointestinal permeability and inflammation in dogs

Journal of Veterinary Internal Medicine.

By: S. Jones n, A. Gaier n, H. Enomoto n, P. Ishii*, R. Pilla*, J. Price*, J. Suchodolski*, J. Steiner* ...

author keywords: canine; dysbiosis; nonsteroidal anti-inflammatory drug; proton pump inhibitor
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Carbazoles; Dog Diseases / chemically induced; Dog Diseases / drug therapy; Dog Diseases / prevention & control; Dogs; Female; Inflammation / chemically induced; Inflammation / drug therapy; Inflammation / veterinary; Male; Omeprazole / pharmacology; Permeability; Prospective Studies
TL;DR: Omeprazole prophylaxis induces fecal dysbiosis and increases intestinal inflammatory markers when coadministered with carprofen to otherwise healthy dogs with no other risk factors for GI bleeding. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: September 9, 2020

2020 review

Advances of exosome isolation techniques in lung cancer

[Review of ]. MOLECULAR BIOLOGY REPORTS, 47(9), 7229–7251.

By: E. Mahgoub*, E. Razmara*, A. Bitaraf*, F. Norouzi*, M. Montazeri*, R. Behzadi-Andouhjerdi*, M. Falahati*, K. Cheng n ...

author keywords: Lung cancer; Exosome; Multi-vesicular bodies; Extracellular vesicles; MicroRNAs
MeSH headings : Biomarkers, Tumor / blood; Biomarkers, Tumor / isolation & purification; Cell-Free Nucleic Acids / blood; Cell-Free Nucleic Acids / isolation & purification; Circulating Tumor DNA / blood; Circulating Tumor DNA / isolation & purification; Exosomes / metabolism; Exosomes / pathology; Humans; Lung Neoplasms / blood; Lung Neoplasms / diagnosis; Lung Neoplasms / pathology
TL;DR: This review summarizes the recent investigations regarding isolation and also the characterization of exosomes of LC cells, and discusses the noncoding RNAs as biomarkers and their applications in the diagnosis and prognosis of LC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 31, 2020

2020 article

Expression of UDP Glucuronosyltransferases2B15and2B17is associated with methylation status in prostate cancer cells

EPIGENETICS.

By: F. Shafiee-Kermani*, S. Carney*, D. Jima n, U. Utin*, L. Farrar*, M. Oputa*, M. Hines*, H. Kinyamu* ...

MeSH headings : DNA Methylation; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase / genetics; Glucuronosyltransferase / metabolism; Humans; Male; Minor Histocompatibility Antigens / genetics; Prostatic Neoplasms / genetics
TL;DR: The results taken together suggest that hypomethylation of the UGT2B15 and UGT 2B17 genes contributes to increased risk of prostate cancer and may provide a putative biomarker or epigenetic target for chemotherapeutics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 17, 2020

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