Works Published in 2002
Displaying works 241 - 260 of 363 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2002 journal article
Analysis of N,N-diethyl-m-toluamide in porcine skin perfusates using solid-phase extraction disks and reversed-phase high-performance liquid chromatography
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 780(1), 45–52.
author keywords: N,N-Diethyl-m-toluamide
MeSH headings : Animals; Chromatography, High Pressure Liquid / methods; DEET / analysis; Insect Repellents / analysis; Permeability; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Skin / chemistry; Swine
TL;DR:
An improved method was developed for determining transdermal diffusion of low levels of DEET following application to an in vitro porcine skin flow-through diffusion cell system and it was determined that DEET permeability in porcines skin was 2.55 x 10(-5)+/-0.54 x 10-5 cm/h.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
An observer study evaluating dual-plane circular-orbit cone- beam brain SPECT
Journal of Nuclear Medicine, 43(11), 1578–1583.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Altered glycosylation of 63- and 68-kilodalton microvillar proteins in Heliothis virescens correlates with reduced Cry1 toxin binding, decreased pore formation, and increased resistance to Bacillus thuringiensis Cry1 toxins
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(11), 5711–5717.
MeSH headings : Animals; Bacillus thuringiensis / chemistry; Bacillus thuringiensis Toxins; Bacterial Proteins / metabolism; Bacterial Proteins / pharmacology; Bacterial Toxins; Binding Sites; Cell Membrane Permeability / drug effects; Drug Resistance; Endotoxins / metabolism; Endotoxins / pharmacology; Glycosylation; Hemolysin Proteins; Lepidoptera / chemistry; Lepidoptera / drug effects; Microvilli / drug effects; Microvilli / metabolism; Microvilli / ultrastructure; Molecular Weight; Oxidation-Reduction
TL;DR:
Evidence is found that a dramatic reduction in toxin binding is responsible for the increased resistance and cross-resistance to Cry1 toxins observed in the YHD2 strain of H. virescens and that this trait correlates with altered glycosylation of specific brush border membrane glycoproteins.
(via Semantic Scholar)
aem.asm.org (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation
AMERICAN JOURNAL OF PATHOLOGY, 161(2), 405–411.
MeSH headings : Animals; Carcinogens / toxicity; Cell Division / genetics; Cell Transformation, Neoplastic / genetics; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases / deficiency; Cyclin-Dependent Kinases / genetics; Keratinocytes / cytology; Keratinocytes / enzymology; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins; Skin Neoplasms / enzymology; Skin Neoplasms / etiology; Skin Neoplasms / genetics; Tetradecanoylphorbol Acetate / toxicity
TL;DR:
The results suggest that therapeutic approaches to inhibit cdk4 activity could provide a target to inhibit tumor development with minimal or no effect in normal tissue.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 article
Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs
Munana, K. R., Vitek, S. M., Tarver, W. B., Saito, M., Skeen, T. M., Sharp, N. J. H., … Haglund, M. M. (2002, October 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 221, pp. 977–983.
MeSH headings : Animals; Cross-Over Studies; Dog Diseases / therapy; Dogs; Electric Stimulation Therapy / adverse effects; Electric Stimulation Therapy / methods; Electric Stimulation Therapy / veterinary; Epilepsy / therapy; Epilepsy / veterinary; Female; Male; Pacemaker, Artificial / veterinary; Safety; Seizures / prevention & control; Seizures / veterinary; Treatment Outcome; Vagus Nerve / physiopathology
TL;DR:
Vagal nerve stimulation is a potentially safe approach to seizure control that appears to be efficacious in certain dogs and should be considered a possible treatment option when antiepileptic medications are ineffective.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2002 journal article
Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus
VIROLOGY, 302(2), 363–372.
author keywords: PRRSV; thymus; thymocyte; T lymphocyte
MeSH headings : Animals; Animals, Newborn; Female; Infectious Disease Transmission, Vertical; Leukocytes, Mononuclear / immunology; Lymphocyte Count; Porcine Reproductive and Respiratory Syndrome / immunology; Porcine Reproductive and Respiratory Syndrome / virology; Porcine respiratory and reproductive syndrome virus / immunology; Pregnancy; Pregnancy, Animal; Swine; Swine Diseases / immunology; Swine Diseases / virology; T-Lymphocyte Subsets / immunology; Thymus Gland / cytology; Thymus Gland / immunology; Uterus / virology
TL;DR:
It is shown that the number of thymocytes undergoing apoptosis was increased twofold in piglets infected with PRRSV and this results help explain the dramatic immunosuppression observed in neonatal animals infected in utero withPRRSV.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
The role of interferon regulatory factors in the cardiac response to viral infection
VIRAL IMMUNOLOGY, 15(1), 17–28.
MeSH headings : Animals; DNA-Binding Proteins / physiology; Interferon Regulatory Factor-1; Interferon Regulatory Factor-2; Interferon Regulatory Factor-3; Interferon-beta / genetics; Interferon-beta / physiology; Mice; Myocarditis / immunology; Phosphoproteins / physiology; Reoviridae Infections / immunology; Repressor Proteins; Transcription Factors / physiology; Transcription, Genetic
TL;DR:
The role of IRF-2 in regulation of IFN-beta expression is cell type-specific and differs between skeletal and cardiac muscle cells, suggesting that the heart may provide a unique environment for IRF function, critical for protection against virus-induced cardiac damage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Single-pass attenuated total reflection Fourier transform infrared spectroscopy for the analysis of proteins in H2O solution
ANALYTICAL CHEMISTRY, 74(16), 4076–4080.
MeSH headings : Animals; Gels; Humans; Protein Structure, Secondary; Proteins / chemistry; Solutions; Spectroscopy, Fourier Transform Infrared / instrumentation; Spectroscopy, Fourier Transform Infrared / methods
TL;DR:
A comparison of replicate protein spectra indicated that the single-pass ATR-FT-IR method yields more reproducible data than those acquired by transmission FT-IR.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 review
Role of the enteric nervous system in the pathophysiology of secretory diarrhea
[Review of ]. JOURNAL OF VETERINARY INTERNAL MEDICINE, 16(3), 222–228.
author keywords: alimentary; enterocolitis; inflammation; neuroimmune
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Proximal ligand motions in H93G myoglobin
EUROPEAN JOURNAL OF BIOCHEMISTRY, 269(19), 4879–4886.
author keywords: resonance Raman; heme; myoglobin; hemoglobin; ligand switch
MeSH headings : Animals; Heme / chemistry; Hydrogen Bonding; In Vitro Techniques; Ligands; Myoglobin / chemistry; Myoglobin / genetics; Photochemistry; Photolysis; Point Mutation; Protein Conformation; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Spectrum Analysis, Raman; Whales
TL;DR:
The data presented here further substantiate the conclusion that a conformationally driven ligand switch exists in photolyzed H93G-*CO and suggest that ligand conformational changes in response to dynamic motions of the globin on the nanosecond and longer time scales are a general feature of the H 93G proximal cavity mutant.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Prostaglandin E-2 and reactive oxygen metabolite damage in the cecum in a pony model of acute colitis
Canadian Journal of Veterinary Research, 66(1), 50–54.
Source: NC State University Libraries
Added: August 6, 2018
2002 review
Probing electronic communication in covalently linked multiporphyrin arrays. A guide to the rational design of molecular photonic devices
[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 35(1), 57–69.
MeSH headings : Electronics; Metalloporphyrins / chemistry; Models, Molecular; Organometallic Compounds / chemistry
TL;DR:
This Account describes studies aimed at understanding the mechanisms of electronic communication in porphyrin-based architectures that undergo excited-state energy migration and ground-state hole/electron hopping.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Pharmacokinetics of azithromycin in foals after i.v. and oral dose and disposition into phagocytes
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 25(2), 99–104.
MeSH headings : Actinomycetales Infections / drug therapy; Actinomycetales Infections / veterinary; Administration, Oral; Animals; Animals, Newborn; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / therapeutic use; Area Under Curve; Azithromycin / administration & dosage; Azithromycin / blood; Azithromycin / pharmacokinetics; Azithromycin / therapeutic use; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid / veterinary; Female; Horse Diseases / drug therapy; Horses / metabolism; Infusions, Intravenous / veterinary; Macrophages, Alveolar / metabolism; Male; Phagocytes / metabolism; Rhodococcus equi
TL;DR:
The properties of azithromycin suggest that it may be an alternative to erythromycin for treatment of Rhodococcus equi pneumonia in foals and its disposition in plasma, polymorphonuclear leukocytes (PMN), and alveolar cells was examined to investigate this possibility.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Neutrophils increase paracellular permeability of restituted ischemic-injured porcine ileum
SURGERY, 132(3), 461–470.
MeSH headings : Animals; Antibodies, Monoclonal / immunology; CD11 Antigens / physiology; CD18 Antigens / physiology; Electric Impedance; Ileum / blood supply; Ileum / metabolism; Ileum / pathology; Ischemia / metabolism; Ischemia / pathology; Neutrophils / physiology; Permeability; Polyethylene Glycols / pharmacology; Superoxide Dismutase / pharmacology; Swine
TL;DR:
Pretreatment with anti-CD11/CD18 monoclonal antibody and superoxide dismutase-polyethylene glycol significantly reduced neutrophil infiltration and normalized transepithelial electrical resistance and mannitol fluxes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Microbial contamination in inoculated shell eggs: I. Effects of layer strain and hen age
POULTRY SCIENCE, 81(5), 715–720.
author keywords: egg; Salmonella enteritidis; Pseudomonas fluorescens; pathogen; spoilage
MeSH headings : Age Factors; Animals; Chickens / genetics; Chickens / physiology; Colony Count, Microbial / veterinary; Egg Shell / microbiology; Eggs / microbiology; Female; Food Microbiology; Kinetics; Pseudomonas fluorescens / growth & development; Pseudomonas fluorescens / physiology; Salmonella enteritidis / growth & development; Salmonella enteritidis / physiology
TL;DR:
The overall results of this study suggest that genetic selection has altered the ability of eggs to resist microbial contamination and that screening for microbial integrity should be considered in the selection process among the laying egg breeders.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 article
Medetomidine, ketamine, and sevoflurane for anesthesia for injured loggerhead sea turtles: 13 cases (1996-2000)
Chittick, E. J., Stamper, M. A., Beasley, J. F., Lewbart, G. A., & Horne, W. A. (2002, October 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 221, pp. 1019–1025.
MeSH headings : Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Blood Gas Analysis / veterinary; Dose-Response Relationship, Drug; Female; Heart Rate / drug effects; Hypnotics and Sedatives; Ketamine; Male; Medetomidine; Methyl Ethers; Partial Pressure; Retrospective Studies; Safety; Sevoflurane; Time Factors; Treatment Outcome; Turtles / injuries; Turtles / physiology
TL;DR:
Results suggest that a combination of medetomidine and ketamine for induction and sevoflurane for maintenance provides safe, effective, controllable anesthesia in injured loggerhead sea turtles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Interaction of RNA with phage display selected peptides analyzed by capillary electrophoresis mobility shift assay
RNA, 8(5), 698–704.
author keywords: anticodon stem and loop; capillary electrophoresis; methylated nucleoside-dependent RNA-peptide; interaction; phage display selected peptides; tRNA
MeSH headings : Amino Acid Sequence; Anticodon / chemistry; Anticodon / genetics; Anticodon / metabolism; Base Sequence; Electrophoresis, Capillary / methods; In Vitro Techniques; Molecular Sequence Data; Nucleic Acid Conformation; Peptide Library; Peptides / chemistry; Peptides / metabolism; RNA, Transfer, Phe / chemistry; RNA, Transfer, Phe / genetics; RNA, Transfer, Phe / metabolism
TL;DR:
Capillary electrophoresis was found to be an efficient and sensitive method for the qualitative analysis of RNA/peptide interaction and should be generally applicable to the study of RNA- peptide (protein) interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Heparin inhibits DNA synthesis and gene expression in alveolar type II cells
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 27(3), 345–352.
MeSH headings : Animals; Cell Division / drug effects; Cells, Cultured; DNA / biosynthesis; DNA / drug effects; Extracellular Matrix / drug effects; Extracellular Matrix / metabolism; Fibroblast Growth Factor 1 / genetics; Fibroblast Growth Factor 1 / metabolism; Fibroblast Growth Factor 1 / pharmacology; Fibroblast Growth Factor 2 / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Heparin / pharmacology; Pulmonary Alveoli / cytology; Pulmonary Alveoli / drug effects; Pulmonary Alveoli / physiology; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases / drug effects; Receptor Protein-Tyrosine Kinases / genetics; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor / drug effects; Receptors, Fibroblast Growth Factor / genetics; Thymidine / metabolism
TL;DR:
It is demonstrated that sulfated molecules in the ABM may play important regulatory role(s) in selected type II cell activities during normal cell homeostasis, turnover, and repair after lung injury.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Folding thermodynamics of model four-strand antiparallel beta-sheet proteins
BIOPHYSICAL JOURNAL, 82(2), 646–659.
MeSH headings : Biophysical Phenomena; Biophysics; Models, Statistical; Models, Theoretical; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Temperature; Thermodynamics
TL;DR:
The thermodynamic properties for three different types of off-lattice four-Strand antiparallel beta-strand protein models interacting via a hybrid Go-type potential have been investigated and exhibit a complex set of protein transitions, consistent with those observed in experimental studies on real proteins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Evaluation of a spontaneous canine model of immunoglobulin E- mediated food hypersensitivity: Dynamic changes in serum and fecal allergen-specific immunoglobulin E values relative to dietary change
Comparative Medicine, 52(4), 316–321.
Source: NC State University Libraries
Added: August 6, 2018
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