Works Published in 2022

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Displaying works 401 - 420 of 652 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2022 article

Site-specific DNA functionalization through the tetrazene-forming reaction in ionic liquids (vol 13, pg 1780, 2022)

Ishizawa, S., Tumurkhuu, M., Gross, E. J., & Ohata, J. (2022, June 7). CHEMICAL SCIENCE, Vol. 13, pp. 6749–6751.

By: S. Ishizawa n, M. Tumurkhuu n, E. Gross n & J. Ohata n

TL;DR: The non-traditional medium-promoted labeling strategy described here provides an alternative design paradigm for future development of chemical tools for applications involving DNA functionalization. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 journal article

Metabolomic Analysis of Lactobacillus acidophilus, L. gasseri, L. crispatus, and Lacticaseibacillus rhamnosus Strains in the Presence of Pomegranate Extract

FRONTIERS IN MICROBIOLOGY, 13.

By: M. Chamberlain n, S. O'Flaherty n, N. Cobian n & R. Barrangou n

author keywords: metabolomics; Lactobacillus; probiotic; pomegranate extract; prebiotic
TL;DR: The growth of the strains with and without the presence of POM were investigated and their carbohydrate utilization and enzyme activity profiles were identified and an untargeted metabolomic approach was utilized to quantitatively and qualitatively define the metabolite profiles of these strains. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 article

Prevalence of Knock-Down Resistance F1534S Mutations in Aedes albopictus (Skuse) (Diptera: Culicidae) in North Carolina

Abernathy, H. A., Hollingsworth, B. D., Giandomenico, D. A., Moser, K. A., Juliano, J. J., Bowman, N. M., … Boyce, R. M. (2022, May 29). JOURNAL OF MEDICAL ENTOMOLOGY, Vol. 5.

author keywords: insecticide resistance; Aedes; mosquito; permethrin; pyrethroid
MeSH headings : Aedes / genetics; Animals; Insecticide Resistance / genetics; Insecticides / pharmacology; Mosquito Vectors / genetics; North Carolina; Prevalence; Pyrethrins / pharmacology
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 journal article

Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(18).

By: L. Tse*, R. Meganck*, K. Araba*, B. Yount*, K. Shaffer*, Y. Hou*, J. Munt*, L. Adams* ...

author keywords: PLAC8; coronavirus; CRISPR; swine acute diarrhea syndrome coronavirus
MeSH headings : Alphacoronavirus / genetics; Animals; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Coronavirus Infections / epidemiology; Swine; Swine Diseases
TL;DR: Using genomewide CRISPR knockout screening, the placenta-associated 8 protein (PLAC8) is identified as an essential host factor for SADS-CoV infection, uncovering a novel antiviral target for CoV infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 journal article

Spray-dried and freeze-dried protein-spinach particles; effect of drying technique and protein type on the bioaccessibility of carotenoids, chlorophylls, and phenolics

FOOD CHEMISTRY, 388.

author keywords: Spinach phytochemicals; Whey protein; Soy protein; Drying; In vitro digestion; Dried ingredients
MeSH headings : Carotenoids / metabolism; Chlorophyll / metabolism; Digestion; Excipients / metabolism; Flavonoids / metabolism; Freeze Drying; Phenols / metabolism; Spinacia oleracea / metabolism
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 journal article

Estimation of Thickness and Speed of Sound for Transverse Cortical Bone Imaging Using Phase Aberration Correction Methods: An In Silico and Ex Vivo Validation Study

APPLIED SCIENCES-BASEL, 12(10).

author keywords: medical beamforming; phase aberration correction; medical tissue characterization; pulse-echo ultrasound; medical signal and image processing
TL;DR: The developed multi-focus method including phase aberration corrections provides local estimations of both cortical thickness and sound velocity and is proposed as a biomarker of cortical bone quality with high clinical potential for the prevention of osteoporotic fractures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: June 13, 2022

2022 journal article

Bacterial Isolates Derived from Nest Soil Affect the Attraction and Digging Behavior of Workers of the Red Imported Fire Ant, Solenopsis invicta Buren

INSECTS, 13(5).

author keywords: Solenopsis invicta; bacterial isolates; behavioral responses; digging behavior
TL;DR: The research results indicate that soil bacteria may mediate ant nest expansion or relocation and foraging tunnel construction and identification of bacterial metabolites that affect RIFA digging behavior merits additional research. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 13, 2022

2022 journal article

Individual and Combined Effects of Paternal Deprivation and Developmental Exposure to Firemaster 550 on Socio-Emotional Behavior in Prairie Voles

TOXICS, 10(5).

By: S. Gillera n, W. Marinello n, M. Nelson n, B. Horman n & H. Patisaul n

author keywords: endocrine disruptors; flame retardants; sexual differentiation; pair bond
TL;DR: Evidence is provided that chemical and social stressors can have unique behavioral effects that differ by sex but may not produce worse outcomes in combination. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 article

Long-term follow up of 44 cats undergoing total hip replacement: Cases from a feline hip registry (2010-2020)

Tilve, V. R., Allaith, S., Girling, S., Moores, A. P., Mulholland, L., Morrison, S., … Comerford, E. (2022, June 1). VETERINARY SURGERY, Vol. 6.

By: V. Tilve, S. Allaith*, S. Girling, A. Moores, L. Mulholland*, S. Morrison, J. Onyett, T. Maddox* ...

MeSH headings : Animals; Arthroplasty, Replacement, Hip / adverse effects; Arthroplasty, Replacement, Hip / veterinary; Cats / surgery; Follow-Up Studies; Hip Prosthesis / veterinary; Humans; Male; Registries; Retrospective Studies; Treatment Outcome
TL;DR: A validated client metrology questionnaire showed clinical improvement in cats following THR, and total hip replacement appears to be a successful surgical treatment for feline hip disease with very good owner satisfaction and acceptable complication rates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 review

Use of Translational, Genetically Modified Porcine Models to Ultimately Improve Intestinal Disease Treatment

[Review of ]. FRONTIERS IN VETERINARY SCIENCE, 9.

By: C. Schaaf n & L. Gonzalez n

author keywords: cystic fibrosis; colorectal cancer; ischemia-reperfusion injury; genetically altered models; intestinal disease; translational porcine model; stem cell reporter model
TL;DR: Recent advances and increased availability of gene editing technologies has led to both novel use of large animal models in clinically relevant intestinal disease research and improved testing of potential therapeutics for these diseases. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 article

Coupling spatial statistics with social network analysis to estimate distinct risk areas of disease circulation to improve risk-based surveillance

Cardenas, N. C., Sanchez, F., Lopes, F. P. N., & Machado, G. (2022, June 25). TRANSBOUNDARY AND EMERGING DISEASES, Vol. 6.

By: N. Cardenas n, F. Sanchez n, F. Lopes* & G. Machado n

author keywords: disease spread; movement flows; non-stationary Gaussian models; risk areas mapping; social network analysis
MeSH headings : Animals; Disease Outbreaks / prevention & control; Disease Outbreaks / veterinary; Equine Infectious Anemia / epidemiology; Farms; Horse Diseases / epidemiology; Horses; Infectious Anemia Virus, Equine; Social Network Analysis
TL;DR: The results demonstrate that animal movements and spatial risk mapping could be used to make informed decisions before issuing animal movement permits, thus potentially reducing the chances of reintroducing infection into areas of low risk. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 review

The Potential of a Protein Model Synthesized Absent of Methionine

[Review of ]. MOLECULES, 27(12).

author keywords: methionine; cysteine; antioxidant; protein; cell; stability; protein synthesis
MeSH headings : Amino Acids; Antioxidants; Cysteine / metabolism; Methionine / chemistry; Proteins / chemistry
TL;DR: A number of novel mechanisms for alternative initiation of protein synthesis have been identified that suggest a potential to bypass the traditional methionine-dependent initiation during times of stress, and a number of examples that demonstrate a potential model for synthesizing a protein in the absence of methamphetamine are discussed. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 13, 2022

2022 article

Comparison of the mechanical properties and anchoring performance of polyvinylidene fluoride and polypropylene barbed sutures for tendon repair

Huang, Y., Cadet, E. R., King, M. W., & Cole, J. H. (2022, June 8). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol. 6.

By: Y. Huang n, E. Cadet*, M. King n & J. Cole n

author keywords: barbed sutures; biomechanics; ex vivo; polypropylene; polyvinylidene fluoride; tendon repair
MeSH headings : Animals; Biomechanical Phenomena; Fluorocarbon Polymers; Polypropylenes; Polyvinyls; Suture Techniques; Sutures; Swine; Tendon Injuries / surgery; Tendons; Tensile Strength
TL;DR: PVDF barbed sutures provided better mechanical properties and improved tissue anchoring performance compared to the barbed PP suture for porcine patellar tendon repair, demonstrating that PVDF monofilament sutURES can be barbed and used effectively for tendon repair. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 9, 2022

2022 journal article

Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure*

JOURNAL OF VETERINARY CARDIOLOGY, 40, 99–109.

By: A. Walker*, T. DeFrancesco n, J. Bonagura n, B. Keene n, K. Meurs n, S. Tou n, K. Kurtz*, B. Aona* ...

author keywords: Canine; Survival; Grain-free; Echocardiography; Nutritional
MeSH headings : Animals; Dogs; Cardiomyopathy, Dilated / diagnosis; Cardiomyopathy, Dilated / veterinary; Diet / veterinary; Dog Diseases / diagnosis; Echocardiography / veterinary; Edible Grain; Heart Failure / complications; Heart Failure / therapy; Heart Failure / veterinary; Retrospective Studies
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 6, 2022

2022 review

A review of the underlying genetics and emerging therapies for canine cardiomyopathies

[Review of ]. JOURNAL OF VETERINARY CARDIOLOGY, 40, 2–14.

By: L. Shen*, A. Estrada*, K. Meurs n, M. Sleeper*, C. Vulpe*, C. Martyniuk*, C. Pacak*

author keywords: Dilated cardiomyopathy; Arrhythmogenic right ventricular cardiomyo-pathy; Gene therapy; Gene editing; Clustered regularly in-terspaced short palin-dromic repeats
MeSH headings : Animals; Arrhythmogenic Right Ventricular Dysplasia / veterinary; Cardiomyopathies / genetics; Cardiomyopathies / therapy; Cardiomyopathies / veterinary; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / therapy; Cardiomyopathy, Dilated / veterinary; Dog Diseases / genetics; Dog Diseases / therapy; Dogs; Heart Failure / veterinary; Mutation
TL;DR: The known genetics of cardiomyopathies in dogs are discussed, existing gene therapy strategies and the status of their development in canines are reviewed, and ongoing challenges in the clinical translation of these technologies for treating heart disease are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 6, 2022

2022 journal article

Direct Detection of Glutathione Biosynthesis, Conjugation, Depletion and Recovery in Intact Hepatoma Cells

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(9).

By: R. Jeffries n, S. Gomez n, J. Macdonald n & M. Gamcsik n

author keywords: glutathione; antioxidant; nuclear magnetic resonance spectroscopy; noninvasive; alkylating agent; metabolism
MeSH headings : Animals; Bioreactors; Bridged Bicyclo Compounds; Carcinoma, Hepatocellular; Glutathione / metabolism; Humans; Liver Neoplasms; Rats
TL;DR: Standard NMR techniques can directly monitor intracellular processes such as glutathione depletion with a time resolution of approximately < 2 min, and are demonstrated to be effective in alginate-encapsulated JM-1 hepatomas. (via Semantic Scholar)
Source: Web Of Science
Added: June 6, 2022

2022 journal article

Mechanism of Methyldehydrofosmidomycin Maturation: Use Olefination to Enable Chain Elongation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 144(18), 8257–8266.

MeSH headings : Alkenes / chemistry; Catalysis; Hydroxylation; Iron / chemistry; Ketoglutaric Acids / metabolism
TL;DR: This work characterized the reactive species, revealed the structure of the reaction intermediate, and used mechanistic probes to investigate the reaction pathway and mechanism, leading to the elucidation of a two-step process in which the first reaction employs a long-lived Fe(IV)-oxo species to trigger C═C bond installation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 6, 2022

2022 journal article

Modeling the Ligand Effect on the Structure of CYP 450 Within the Density Functional Theory

JOURNAL OF PHYSICAL CHEMISTRY A, 126(18), 2818–2824.

MeSH headings : Cysteine / chemistry; Density Functional Theory; Heme / chemistry; Iron / chemistry; Ligands
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 6, 2022

2022 journal article

Cupric Ions Selectively Modulate TRAAK-Phosphatidylserine Interactions

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 144(16), 7048–7053.

By: Y. Zhu*, S. Schrecke*, S. Tang*, M. Odenkirk n, T. Walker*, L. Stover*, J. Lyu*, T. Zhang* ...

MeSH headings : Cations, Divalent / metabolism; Phosphatidylserines; Potassium Channels, Tandem Pore Domain / chemistry; Potassium Channels, Tandem Pore Domain / metabolism
TL;DR: High-resolution native mass spectrometry enables the determination of equilibrium binding constants for distinct Cu2+-bound stoichiometries and uncovered the highest coupling factor corresponds to a 1:1 PS-to-Cu2+ ratio, which brings forth the role of cupric ions as an essential cofactor in selective TRAAK-PS interactions. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 6, 2022

2022 article

Detection of Escherichia coli and Enterococcus spp. in dogs with polymicrobial urinary tract infections: A 5-year retrospective study

Walker, G. K., Yustyniuk, V., Shamoun, J., Jacob, M. E., Correa, M., Vaden, S. L., & Borst, L. B. (2022, May 27). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: G. Walker n, V. Yustyniuk*, J. Shamoun n, M. Jacob n, M. Correa n, S. Vaden n, L. Borst n

author keywords: antibiotics; bacteriuria; cystitis; urine culture
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteriuria / drug therapy; Bacteriuria / epidemiology; Bacteriuria / veterinary; Dog Diseases / drug therapy; Dogs; Doxycycline; Enterococcus; Escherichia coli; Escherichia coli Infections / drug therapy; Escherichia coli Infections / veterinary; Gentamicins; Humans; Retrospective Studies; Urinary Tract Infections / drug therapy; Urinary Tract Infections / epidemiology; Urinary Tract Infections / veterinary
TL;DR: Polymicrobial UTI had more frequent adverse clinical outcomes for dogs and was more prevalent than monomicrobial UTI, and isolate antimicrobial resistance was more frequently resistant to doxycycline and gentamicin. (via Semantic Scholar)
Source: Web Of Science
Added: June 6, 2022

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