Works Published in 2022

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Displaying works 61 - 80 of 82 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2022 article

Bioaccessibility and intestinal cell uptake of carotenoids and chlorophylls differ in powdered spinach by the ingredient form as measured using in vitro gastrointestinal digestion and anaerobic fecal fermentation models

Hayes, M., Mohamedshah, Z., Chadwick-Corbin, S., Hoskin, R., Iorizzo, M., Lila, M. A., … Ferruzzi, M. G. (2022, March 8). FOOD & FUNCTION, Vol. 13.

MeSH headings : Anaerobiosis; Caco-2 Cells; Carotenoids / metabolism; Chlorophyll; Digestion; Fermentation; Health Promotion; Humans; Powders; Spinacia oleracea / metabolism
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 31, 2022

2022 article

Mechanisms, Biomarkers, and Therapeutics Involved in Inflammatory Disorders and Tissue Repair 2021

Goncalves, R. V., Sarandy, M. M., Esposito, D., & Gouveia Peluzio, M. do C. (2022, March 20). OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, Vol. 2022.

MeSH headings : Biomarkers; Wound Healing
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 30, 2022

2022 journal article

Effect of Wild Blueberry Metabolites on Biomarkers of Gastrointestinal and Immune Health In Vitro

Immuno, 2(2), 293–306.

By: T. Rathinasabapathy n, J. Lomax n, K. Srikanth*, D. Esposito n, C. Kay n & S. Komarnytsky n

TL;DR: Wild blueberries are a rich source of dietary fiber and (poly)phenols with gastrointestinal and immune health-promoting properties, however, their mechanisms of action on the intestinal epithelial cells and transient tissue macrophages remain to be elucidated. (via Semantic Scholar)
Source: ORCID
Added: March 30, 2022

2022 review

Enhancing the Cognitive Effects of Flavonoids With Physical Activity: Is There a Case for the Gut Microbiome?

[Review of ]. FRONTIERS IN NEUROSCIENCE, 16.

By: C. Cheatham*, D. Nieman*, A. Neilson n & M. Lila n

author keywords: age-related; cognition; neuroprotective; phenolic metabolites; prebiotic flavonoids; exercise; microbiome
TL;DR: There is a potential for combined impacts of flavonoids intake and physical exertion on cognitive function, as modulated by the gut microbiome, and that the combination of a flavonoid-rich diet and routine aerobic exercise may potentiate cognitive benefits and reduce cognitive decline in an aging population, via mechanisms mediated by the Gut microbiome. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 28, 2022

2022 journal article

Foaming characteristics and impact of ethanol pretreatment in drying behavior and physical characteristics for avocado pulp powder obtained by foam mat drying

Journal of Food Science.

Roberta Targino Hoskin

author keywords: foam properties; food preservation; food processing; mathematical modeling; organic solvent
MeSH headings : Desiccation / methods; Ethanol; Persea; Powders / chemistry; Water
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: March 23, 2022

2022 journal article

The constitutive activation of TLR4-IRAK1-NF kappa B axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients

FREE RADICAL BIOLOGY AND MEDICINE, 181, 1–13.

By: V. Cordone*, F. Ferrara*, A. Pecorelli n, A. Guiotto*, A. Vitale*, F. Amicarelli*, C. Cervellati*, J. Hayek*, G. Valacchi n

author keywords: MeCP2; p65; Oxinflammation; Interleukin-18; Interleukin-1 beta
MeSH headings : Humans; Inflammasomes / genetics; Inflammasomes / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; Leukocytes, Mononuclear / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Toll-Like Receptor 4 / genetics
TL;DR: The deregulation of inflammasome components was even found in THP-1 cells silenced for MECP2 and importantly, in plasma compartment of RTT subjects, from the earliest stages of the pathology or in correlation with the severity of MeCP2 mutations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 14, 2022

2022 journal article

Continuous flow microwave-assisted aqueous extraction of pomace phytoactives for production of protein-polyphenol particles and a protein-enriched ready-to-drink beverage

Future Foods, 5, 100137.

By: R. Hoskin n, N. Plundrich, A. Vargochik & M. Lila n

Source: ORCID
Added: March 4, 2022

2022 article

Exploring the Contribution of (Poly)phenols to the Dietary Exposome Using High Resolution Mass Spectrometry Untargeted Metabolomics

Li, Y.-Y., Rushing, B., Schroder, M., Sumner, S., & Kay, C. D. (2022, February 25). MOLECULAR NUTRITION & FOOD RESEARCH, Vol. 2.

By: Y. Li*, B. Rushing*, M. Schroder*, S. Sumner* & C. Kay n

author keywords: dietary exposome; dietary exposome library (DEL); metabolites; polyphenols; untargeted metabolomics
MeSH headings : Humans; Chromatography, Liquid; Phenols; Tandem Mass Spectrometry / methods; Phenol; Exposome; Metabolomics / methods; Phytochemicals
TL;DR: The DEL continues to expand with the aim to provide evidence‐based data for dietary metabolites in exposome research and inform the development of dietary intervention strategies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 26, 2022

2022 article

Estimation of nutritional postharvest losses along food value chains: A case study of three key food security commodities in sub-Saharan Africa

Bechoff, A., Shee, A., Mvumi, B. M., Ngwenyama, P., Debelo, H., Ferruzzi, M. G., … Tomlins, K. I. (2022, February 4). FOOD SECURITY.

author keywords: Postharvest nutrient loss; Postharvest loss; Food system; Human nutritional requirements; Nutrient loss prediction
Source: Web Of Science
Added: February 21, 2022

2022 journal article

Improved High-Quality Genome Assembly and Annotation of Pineapple (Ananas comosus) Cultivar MD2 Revealed Extensive Haplotype Diversity and Diversified FRS/FRF Gene Family

GENES, 13(1).

By: A. Yow n, H. Bostan n, R. Castanera*, V. Ruggieri, M. Mengist n, J. Curaba n, R. Young*, N. Gillitt*, M. Iorizzo n

author keywords: pineapple MD2; Ananas comosus; improved assembly; haplotype diversity; FHY3; FAR1 genes; FRS; FRF genes
MeSH headings : Ananas / genetics; Ananas / growth & development; Chromosome Mapping; Chromosomes, Plant / genetics; Gene Expression Regulation, Plant; Genetic Variation; Genome, Plant; Genomics; Haplotypes; Molecular Sequence Annotation / methods; Plant Proteins / genetics; Sequence Analysis, DNA
TL;DR: The new MD2 assembly will serve as a new reference for genetic and genomic studies in pineapple, and over 48% of the predicted genes harbored potential deleterious mutations, indicating that the high level of heterozygosity in this species contributes to maintaining functional alleles. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 14, 2022

2022 review

All Polyphenols Are Not Created Equal: Exploring the Diversity of Phenolic Metabolites

[Review of ]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70(7), 2077–2091.

By: C. Vong n, T. Rathinasabapathy n, M. Moncada n & S. Komarnytsky n

Contributors: C. Vong n, T. Rathinasabapathy n, M. Moncada n & S. Komarnytsky n

author keywords: (poly)phenols; phenolic acids; microbiome; microbial catabolism; methylation
MeSH headings : Antioxidants; Flavonoids / metabolism; Humans; Phenols / chemistry; Polyphenols / metabolism; Tannins
TL;DR: There is a critical need for precise identification of the individual phenolic metabolite signatures originating from different polyphenol groups to enable future translation of these findings into break-through nutritional interventions and dietary guidelines. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 12, 2022

2022 review

Plant-Based Support of Respiratory Health during Viral Outbreaks

[Review of ]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70(7), 2064–2076.

By: T. Rathinasabapathy n, L. Sakthivel* & S. Komarnytsky n

Contributors: T. Rathinasabapathy n, L. Sakthivel* & S. Komarnytsky n

author keywords: licorice; coneflower; ginger; mullein; horehound; elderberry; nettle; antiviral; anti-inflammatory; expectorant; COVID-19
MeSH headings : Disease Outbreaks; Humans; Phytotherapy; Plant Extracts / pharmacology; Respiratory System; Virus Diseases / drug therapy
TL;DR: Investigating metabolites and their botanical sources holds potential to uncover new mediators of the respiratory health outcomes as well as molecular targets for future break-through therapeutic interventions targeting respiratory viral outbreaks. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 12, 2022

2022 article

Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study

Racine, K. C., Iglesias-Carres, L., Herring, J. A., Ferruzzi, M. G., Kay, C. D., Tessem, J. S., & Neilson, A. P. (2022, January 31). (Vol. 1). Vol. 1.

By: K. Racine, L. Iglesias-Carres, J. Herring, M. Ferruzzi, C. Kay*, J. Tessem, A. Neilson

Source: ORCID
Added: February 2, 2022

2022 journal article

A note on the early transcriptional response in leaves and root of potato plants to cadmium exposure

IRISH JOURNAL OF AGRICULTURAL AND FOOD RESEARCH, 60(1), 27–32.

author keywords: Cadmium; gene expression; potato; RNA-seq; transcriptome
TL;DR: This study is the first report on the transcriptome-wide response of potato to Cd stress, providing insight into the molecular mechanisms involved in the response and identifying genes involved in photosynthesis and autophagy being up-regulated and down-regulated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: January 18, 2022

2022 journal article

Osmoporation is a versatile technique to encapsulate fisetin using the probiotic bacteria Lactobacillus acidophilus

Applied Microbiology and Biotechnology.

author keywords: Cell-based carriers; Bioactive compounds; Bioaccessibility; Food biotechnology
MeSH headings : Flavonols; Lactobacillus; Lactobacillus acidophilus; Probiotics; Spectroscopy, Fourier Transform Infrared
TL;DR: It is demonstrated that osmoporation using probiotic L. acidophilus is a simple, versatile, and efficient technique to encapsulate and deliver lipophilic fisetin for food applications and the enhancement of f isetin bioaccessibility by osmiporated biocapsules is shown for the first time in the literature. (via Semantic Scholar)
Source: ORCID
Added: January 14, 2022

2022 review

The berry health tool chest - an evidence map and interactive resource

[Review of ]. NUTRITION REVIEWS, 80(1), 68–77.

By: K. Kay n, R. Strauch n, C. Granillo n, M. Bame n, J. Xiong n, A. Mast n, B. Burton-Freeman*, C. Kay n, M. Lila n

author keywords: berry; clinical trial design; dietary intervention; evidence mapping; health criteria
MeSH headings : Eating; Fruit; Humans
TL;DR: The development and utility of the "Berry Health Tool Chest," an evidence map summarizing trial design features of studies characterizing the impact of berry consumption upon human health biomarkers, are described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 3, 2022

2022 journal article

Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge: Results from a double blind, randomized controlled trial in metabolic syndrome participants

CLINICAL NUTRITION, 41(1), 165–176.

By: P. Curtis*, L. Berends*, V. Velpen*, A. Jennings, L. Haag*, P. Chandra n, C. Kay n, E. Rimm*, A. Cassidy

author keywords: Metabolic syndrome; Postprandial assessment; Energy-dense meal challenge; Blueberry anthocyanins; Flavonoids; Cardiovascular disease risk
MeSH headings : Aged; Anthocyanins / administration & dosage; Anthocyanins / blood; Anthocyanins / urine; Blood Glucose / metabolism; Blood Pressure / drug effects; Blueberry Plants; Diet, Carbohydrate Loading / adverse effects; Diet, High-Fat / adverse effects; Double-Blind Method; Endothelium, Vascular / drug effects; Energy Intake / drug effects; Female; Humans; Insulin / blood; Lipoproteins / blood; Male; Meals / drug effects; Metabolic Syndrome / metabolism; Middle Aged; Postprandial Period / drug effects; Pulse Wave Analysis; Vascular Stiffness / drug effects
TL;DR: It is found that adding blueberries to a high-fat/high-sugar meal affected the postprandial cardiometabolic response over 24 h and improved HDL-C and Apo-A1, but not LDL-C, TG, or ApO-B. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 27, 2021

2022 journal article

Comparative multi-parameters approach to dissect texture subcomponents of highbush blueberry cultivars at harvest and postharvest

POSTHARVEST BIOLOGY AND TECHNOLOGY, 183.

By: L. Giongo*, M. Ajelli*, M. Pottorff n, P. Perkins-Veazie n & M. Iorizzo n

author keywords: Blueberry; Fruit quality; Post-harvest; Shelf life storage; Texture; Texture analysis; Texture profile analysis; Vaccinium
Source: Web Of Science
Added: October 26, 2021

2022 journal article

Structural requirements of flavonoids for the selective inhibition of alpha-amylase versus alpha-glucosidase

FOOD CHEMISTRY, 370.

author keywords: Flavonoids structure; Protein structure; Endo-type alpha-amylase; Exo-type alpha-glucosidase; Selective inhibition
MeSH headings : Flavonoids; Humans; Starch; alpha-Amylases; alpha-Glucosidases
TL;DR: In the present study, 14 structurally unique flavonoids were screened to systematically investigate structural requirements for selectively inhibiting human α-amylase versus α-glucosidase to obtain a slow but complete starch digestion for health benefit. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 12, 2021

2022 journal article

Foaming and sensory characteristics of protein-polyphenol particles in a food matrix

Food Hydrocolloids.

By: J. Diaz n, E. Foegeding n, L. Stapleton, C. Kay n, M. Iorizzo n, M. Ferruzzi n, M. Lila n

author keywords: Particles; Polyphenols; Proteins; Foaming; Sensory; Structure
UN Sustainable Development Goal Categories
Source: ORCID
Added: August 26, 2021

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