Works Published in 2010
Displaying works 61 - 80 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 journal article
Utilization of microparticles in next-generation assays for microflow cytometers
Analytical and Bioanalytical Chemistry, 398(6), 2373–2382.
author keywords: Microparticle; Flow cytometry; Microfluidics; Microflow cytometer; Biosensors
MeSH headings : Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Calibration; Equipment Design; Flow Cytometry / instrumentation; Flow Cytometry / methods; Light; Magnetics; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Microspheres; Particle Size; Scattering, Radiation
TL;DR:
This work reviews the progress of microparticle-based assays in microflow cytometry in terms of the advantages and limitations of each approach, and singlexed assays using coded microspheres provide sensitive assays for on-site micro flow cytometers.
(via Semantic Scholar)
europepmc.org (repository)
Source: Crossref
Added: August 28, 2020
2010 journal article
Simultaneous monitoring of dopamine concentration at spatially different brain locations in vivo
Biosensors and Bioelectronics, 25(5), 1179–1185.
author keywords: Dopamine; Microelectrodes; Electrode arrays; In vivo electrochemistry; FSCV
MeSH headings : Animals; Biosensing Techniques / instrumentation; Corpus Striatum / metabolism; Dopamine / analysis; Electrochemistry / instrumentation; Electrodes, Implanted; Equipment Design; Equipment Failure Analysis; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution
TL;DR:
This work presents one of the first FSCV microelectrode arrays (MEA) implemented in vivo with the ability to sample from different regions in close spatial proximity (equidistant within 1mm), manufactured from fused silica capillaries and a microfabricated electrode spacer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2010 conference paper
Design and implementation of an embedded system for neural-controlled artificial legs
2010 IEEE Workshop on Health Care Management (WHCM). Presented at the 2010 IEEE Workshop on Health Care Management (WHCM).
Contributors: A. Lin, X. Zhang *, H. Huang* & Q. Yang *
Event: 2010 IEEE Workshop on Health Care Management (WHCM)
TL;DR:
A design and partial implementation of an embedded system as a part of neural-machine interface (NMI) for neural-controlled artificial legs shows the feasibility of real time processing of neural controlled artificial legs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions
(OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
2010 conference paper
Integrating neuromuscular and cyber systems for neural control of artificial legs
Proceedings of the 1st ACM/IEEE International Conference on Cyber-Physical Systems - ICCPS '10, 129–138.
Contributors: H. Huang* , Y. Sun *, Q. Yang *, F. Zhang *, X. Zhang *, Y. Liu *, J. Ren *, F. Sierra*
Event: the 1st ACM/IEEE International Conference
TL;DR:
A new deciphering algorithm, composed of an EMG pattern classifier and finite state machine, was developed to identify the user's intended lower limb movements and a trust management mechanism was designed to handle unexpected sensor failures and signal disturbances.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
2010 conference paper
Design and implementation of a special purpose embedded system for neural machine interface
2010 IEEE International Conference on Computer Design, 166–172.
Contributors: X. Zhang *, H. Huang* & Q. Yang *
Event: 2010 IEEE International Conference on Computer Design (ICCD 2010)
TL;DR:
The results demonstrate the feasibility of a self-contained, low power, and high performance real-time neural-machine interface for artificial legs.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
2010 journal article
Study of stability of time-domain features for electromyographic pattern recognition
Journal of NeuroEngineering and Rehabilitation, 7(1), 21.
Contributors: D. Tkach*, H. Huang* & T. Kuiken *
MeSH headings : Adult; Algorithms; Electrodes; Electromyography / instrumentation; Electromyography / methods; Female; Humans; Isometric Contraction / physiology; Male; Muscle Fatigue / physiology; Muscle, Skeletal / physiology; Pattern Recognition, Automated / methods; Time
TL;DR:
Investigating the stability of time-domain EMG features during changes in the EMG signals and identifying the feature sets that would provide the most robust EMG pattern recognition and developing effective classifier training strategies are suggested to further improve the robustness of HMIs based on EMg pattern recognition.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
2010 journal article
Design of a robust EMG sensing interface for pattern classification
Journal of Neural Engineering, 7(5), 056005.
Contributors: H. Huang* , F. Zhang, Y. Sun & H. He
MeSH headings : Adult; Aged; Artificial Limbs; Electromyography / classification; Electromyography / instrumentation; Electromyography / methods; Equipment Design / instrumentation; Equipment Design / methods; Female; Humans; Male; Middle Aged; Muscle, Skeletal / physiology
TL;DR:
The results showed that the SFD module maintained classification performance when one signal was distorted and recovered about 20% of classification accuracy when four signals were distorted simultaneously, which implies the promise of the designed sensor interface for providing a reliable neural–machine interface for artificial legs.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
2010 journal article
The Development and Validation of a LIPUS System With Preliminary Observations of Ultrasonic Effects on Human Adult Stem Cells
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 57(9), 1977–1984.
MeSH headings : Adipose Tissue / cytology; Adult; Adult Stem Cells / cytology; Adult Stem Cells / diagnostic imaging; Bone Marrow Cells / cytology; Calcium / analysis; Calcium / metabolism; Cell Growth Processes / physiology; Cells, Cultured; DNA / chemistry; Humans; Reproducibility of Results; Ultrasonics / instrumentation; Ultrasonics / methods; Ultrasonography
TL;DR:
The custom LIPUS system designed and validated by exploring the effects of using different pulse repetition frequency (PRF) parameters on human adipose derived adult stem cells and bone marrow derived mesenchymal stem cells was successfully designed to allow extreme parameter variation, specifically PRF, and encourages further studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Uniformity of drug payload and its effect on stability of solid lipid nanoparticles containing an ester prodrug
ACS Nano, 5(1), 209–216.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Microreplication of laser-fabricated surface and three-dimensional structures
JOURNAL OF OPTICS, 12(12).
author keywords: microreplication; indirect rapid prototyping; soft lithography; femtosecond lasers; two-photon polymerization; biomedical engineering
TL;DR:
Any laser-generated surface topography as well as three-dimensional structures can be replicated in various materials without losing the original geometry and it is demonstrated that microstructures have strong influence on morphology and localization of fibroblasts whereas neuroblastoma cells are not negatively affected.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
In Situ Monitoring of Adipogenesis with Human-Adipose-Derived Stem Cells Using Surface-Enhanced Raman Spectroscopy
APPLIED SPECTROSCOPY, 64(11), 1227–1233.
author keywords: Raman spectroscopy; Adipogenesis; Stem cells; Surface-enhanced Raman spectroscopy; SERS
MeSH headings : Adipogenesis / physiology; Adipose Tissue / cytology; Adipose Tissue / metabolism; Adult; Cells, Cultured; Endocytosis; Female; Gold Colloid / chemistry; Gold Colloid / pharmacokinetics; Humans; Metal Nanoparticles / chemistry; Microscopy, Electron, Transmission; Spectrum Analysis, Raman / methods; Stem Cells / cytology; Stem Cells / metabolism
TL;DR:
It is shown that intracellular SERS is able to detect the production of lipids as little as one day after the onset of adipogenesis and that a complex interplay between lipids, proteins, and chemical messengers can be observed shortly thereafter.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
Application of Low-Frequency Alternating Current Electric Fields Via Interdigitated Electrodes: Effects on Cellular Viability, Cytoplasmic Calcium, and Osteogenic Differentiation of Human Adipose-Derived Stem Cells
TISSUE ENGINEERING PART C-METHODS, 16(6), 1377–1386.
MeSH headings : Adipose Tissue / cytology; Adult Stem Cells / cytology; Adult Stem Cells / metabolism; Adult Stem Cells / physiology; Calcium / metabolism; Cell Differentiation / physiology; Cell Proliferation; Cell Survival / physiology; Cells, Cultured; Cytoplasm / metabolism; Electric Stimulation / methods; Electricity; Electrodes; Humans; Osteoblasts / metabolism; Osteoblasts / physiology; Osteogenesis / physiology
TL;DR:
This is the first study to evaluate the effects of sinusoidal AC electric fields on hASCs and to demonstrate that acute and chronic electric field exposure can significantly increase intracellular calcium signaling and the deposition of accreted calcium under osteogenic stimulation, respectively.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Characterization of Local pH Changes in Brain Using Fast-Scan Cyclic Voltammetry with Carbon Microelectrodes
ANALYTICAL CHEMISTRY, 82(23), 9892–9900.
MeSH headings : 3,4-Dihydroxyphenylacetic Acid / chemistry; Animals; Brain / metabolism; Carbon / chemistry; Electrochemical Techniques / methods; Flow Injection Analysis; Hydrogen-Ion Concentration; Male; Microelectrodes; Rats; Rats, Sprague-Dawley
TL;DR:
Hypercapnia is demonstrated to be a useful tool to induce robust in vivo pH changes, allowing confirmation of the pH signal observed with FSCV and an extra peak relating to the capacitive nature ofthe pH CV was identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
Transparent magnetic photoresists for bioanalytical applications
BIOMATERIALS, 31(33), 8810–8817.
author keywords: Magnetism; Photolithography; Biocomaptibility; Micropatterning; MTT assay; Cell adhesion
MeSH headings : Absorption; Animals; Biomedical Technology / instrumentation; Cell Line; Cell Proliferation; Cell Separation; Colorimetry; Ferric Compounds / chemistry; Humans; Magnetics / instrumentation; Nanoparticles / ultrastructure; Photochemistry / instrumentation
TL;DR:
Uniformly transparent magnetic photoresists were developed for microdevices that require high transparency as well as consistent magnetism across the structure and should find wide use in the fabrication of microstructures for bioanalytical technologies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Microtable arrays for culture and isolation of cell colonies
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 398(6), 2595–2604.
author keywords: Microtable; Micropallet; Microfabrication; 1002F; SU-8; Cell separation; Cell array
MeSH headings : Cell Culture Techniques / instrumentation; Cell Culture Techniques / methods; Cell Separation / instrumentation; Cell Separation / methods; Culture Media; Equipment Design; HeLa Cells; Humans; Microarray Analysis / instrumentation; Microarray Analysis / methods; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Surface Properties
TL;DR:
Three-dimensional structures were microfabricated by a novel two-step photolithography process to create a unique array platform for cell biology applications and proved an efficient method for isolating colonies from the arrays with 100% of selected colonies competent to expand following release from the array.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
High-Resolution, High-Contrast Ultrasound Imaging Using a Prototype Dual-Frequency Transducer: In Vitro and In Vivo Studies
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 57(8), 1772–1781.
MeSH headings : Animals; Blood Flow Velocity; Cattle; Contrast Media / chemistry; Kidney / blood supply; Kidney / diagnostic imaging; Microbubbles; Muscle, Skeletal; Phantoms, Imaging; Rats; Rats, Sprague-Dawley; Renal Circulation / physiology; Transducers; Ultrasonography / instrumentation; Ultrasonography / methods
TL;DR:
This probe demonstrates contrast imaging capability with significant tissue suppression, enabling high-resolution contrast-enhanced images of microvascular blood flow, and can readily produce radiation force on flowing contrast agents, which may be beneficial for targeted imaging or therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Two Photon Polymerization-Micromolding of Polyethylene Glycol-Gentamicin Sulfate Microneedles
ADVANCED ENGINEERING MATERIALS, 12(4), B77–B82.
TL;DR:
In this study, a photopolymerization‐micromolding technique was used to fabricate microneedle arrays from a photosensitive material containing polyethylene glycol 600 diacrylate, gentamicin sulfate, and a photoinitiator that inhibited growth of Staphylococcus aureus bacteria.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Micromolded arrays for separation of adherent cells
Lab on a Chip, 10(21), 2917–2924.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Medical prototyping using two photon polymerization
MATERIALS TODAY, 13(12), 42–48.
TL;DR:
In this review, the use of two photon polymerization for fabrication of several types of small-scale medical devices, including microneedles, artificial tissues, microfluidic devices, pumps, sensors, and valves, from computer models is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Using surface-enhanced Raman spectroscopy to probe for genetic markers on single-stranded DNA
Journal of Biomedical Optics, 15(2).
Source: NC State University Libraries
Added: August 6, 2018
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