Works Published in 2003
Displaying works 41 - 60 of 72 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2003 journal article
Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(15), 8957–8962.
MeSH headings : ATP-Binding Cassette Transporters / genetics; ATP-Binding Cassette Transporters / metabolism; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Biological Transport, Active; Chromosome Mapping; DNA, Bacterial / genetics; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Genome, Bacterial; Lac Repressors; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Molecular Sequence Data; Multigene Family; Mutation; Oligosaccharides / metabolism; Operon; Phenotype; Phylogeny; Repressor Proteins / genetics; Repressor Proteins / metabolism; Sequence Homology, Nucleic Acid; Species Specificity
TL;DR:
This is a description of a previously undescribed gene locus involved in transport and catabolism of FOS compounds, which can promote competition of beneficial microorganisms in the human gastrointestinal tract.
(via Semantic Scholar)
www.pnas.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster
CURRENT BIOLOGY, 13(21), 1888–1893.
MeSH headings : Alleles; Animals; California; Crosses, Genetic; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Epistasis, Genetic; Female; Genes, erbB-1 / genetics; Genetic Variation; Inbreeding; Linkage Disequilibrium; Male; Photoreceptor Cells, Invertebrate / anatomy & histology; Polymorphism, Single Nucleotide; Selection, Genetic; Sequence Analysis, DNA
TL;DR:
Replication of the strongest associations with an independent sample of 302 phenotypically extreme individuals derived from 1000 crosses of Egfr(E1) to freshly trapped males and a tendency for the rarer alleles to have more disrupted eye development suggests that mutation-selection balance is a possible mechanism contributing to maintaining cryptic variation for Egfr.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Elevation of transgene expression level by flanking matrix attachment regions (MAR) is promoter dependent: a study of the interactions of six promoters with the RB7 3 ' MAR
TRANSGENIC RESEARCH, 12(1), 3–12.
author keywords: gene silencing; matrix attachment regions; transformation; transgene expression
MeSH headings : 3' Untranslated Regions / genetics; DNA Primers / chemistry; Gene Expression Regulation, Plant; Genes, Plant / physiology; Glucuronidase / genetics; Glucuronidase / metabolism; Hot Temperature; Nuclear Matrix / physiology; Plant Leaves / genetics; Plant Leaves / growth & development; Plants, Genetically Modified / genetics; Plants, Genetically Modified / growth & development; Polymerase Chain Reaction; Promoter Regions, Genetic / genetics; Tobacco / genetics; Tobacco / growth & development; Transformation, Genetic; Transgenes / physiology; Up-Regulation
TL;DR:
Most transgenes flanked by RB7 MAR elements showed a large reduction in the number of low expressing GUS transformants relative to control constructs without MARs, which is important for understanding the role of matrix attachment region in transgene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 journal article
Early allelic selection in maize as revealed by ancient DNA
SCIENCE, 302(5648), 1206–1208.
MeSH headings : Alleles; Archaeology; Biological Evolution; Crops, Agricultural / genetics; DNA, Plant / genetics; DNA-Binding Proteins / genetics; DNA-Binding Proteins / physiology; Gene Frequency; Genes, Plant; Genetic Variation; Mass Spectrometry; Mexico; Plant Proteins / genetics; Plant Proteins / physiology; Selection, Genetic; Southwestern United States; Time Factors; Transcription Factors / genetics; Transcription Factors / physiology; Zea mays / genetics
TL;DR:
This work has analyzed three genes involved in the control of plant architecture, storage protein synthesis, and starch production from archaeological maize samples from Mexico and the southwestern United States to reveal that the alleles typical of contemporary maize were present in Mexican maize by 4400 years ago.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Analysis of trans-silencing interactions using transcriptional silencers of varying strength and targets with and without flanking nuclear matrix attachment regions
TRANSGENIC RESEARCH, 12(3), 305–318.
author keywords: matrix attachment region; tobacco; transcriptional gene silencing; transgene expression; trans-silencing
MeSH headings : Gene Silencing; Inheritance Patterns; Matrix Attachment Regions / genetics; Seedlings / genetics; Sequence Homology; Silencer Elements, Transcriptional; Tobacco / genetics; Transcription, Genetic
TL;DR:
The results are consistent with a model in which transcriptional silencing is triggered by transcription of sequences during the early stages of embryo or seedling development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 journal article
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes
NUCLEIC ACIDS RESEARCH, 31(7), 1805–1812.
MeSH headings : Base Sequence; Binding Sites; DNA / genetics; DNA / metabolism; DNA Restriction Enzymes / classification; DNA Restriction Enzymes / genetics; DNA Restriction Enzymes / metabolism; Methyltransferases / classification; Methyltransferases / genetics; Methyltransferases / metabolism; Terminology as Topic
TL;DR:
A nomenclature is described for restriction endon nucleases, DNA methyltransferases, homing endonucleases and related genes and gene products that provides explicit categories for the many different Type II enzymes now identified and provides a system for naming the putative genes found by sequence analysis of microbial genomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 review
Time scale of eutherian evolution estimated without assuming a constant rate of molecular evolution
[Review of ]. GENES & GENETIC SYSTEMS, 78(4), 267–283.
author keywords: Bayesian method; divergence times; variation of evolutionary
MeSH headings : Animals; Bayes Theorem; Evolution, Molecular; Fossils; Genetic Variation; Humans; Mathematics; Models, Biological; Models, Genetic; Phylogeny; Probability; Time Factors
TL;DR:
This Bayesian method not only takes account of the variation of molecular evolutionary rate among lineages and among genes, but it also incorporates fossil evidence via constraints on node times and is expected to increase the accuracy of divergence time estimates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 article
Population genomics: Finding the dispatch variants of mass disruption
Gibson, G. (2003, December 2). CURRENT BIOLOGY, Vol. 13, pp. R901–R903.
MeSH headings : DNA-Binding Proteins / genetics; Evolution, Molecular; Gene Expression Regulation; Gene Frequency; Genetics, Population; Genome, Human; Geography; Humans; Interleukin-4 / genetics; Interleukin-4 / metabolism; Models, Genetic; NFATC Transcription Factors; Nuclear Proteins; Polymorphism, Single Nucleotide / genetics; Transcription Factors / genetics
TL;DR:
A study of positive selection on the promoter of the human interleukin-4 gene suggests that some disease-promoting alleles might be identified as polymorphic sites that affect transcription and occur at different frequencies among human populations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 review
Evolutionary dynamics of duplicated genes in plants
[Review of ]. MOLECULAR PHYLOGENETICS AND EVOLUTION, 29(3), 396–409.
author keywords: gene duplication; genome duplication; polyploidy; evolutionary genomics
MeSH headings : Adaptation, Biological / genetics; Evolution, Molecular; Gene Duplication; Genes, Duplicate / genetics; Phylogeny; Plants / genetics; Polyploidy
TL;DR:
This review discusses recent gene duplication analyses in plants, focusing on the molecular and evolutionary dynamics occurring at three different timescales following duplication: initial establishment and persistence of cytotypes, interactions among duplicate gene copies, and longer term differentiation between duplicated genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome
NATURE GENETICS, 35(2), 180–184.
MeSH headings : Animals; Biotransformation; Drosophila melanogaster / genetics; Epistasis, Genetic; Gene Expression Regulation; Odorants; Smell / physiology; Transcription, Genetic
TL;DR:
Quantitative complementation tests of mutations at coregulated genes with the smi mutations showed that in most cases (67%) epistatic interactions for olfactory behavior mirrored epistasis at the level of transcription, thus identifying new candidate genes regulating olfaction behavior.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Perspective: Evolution and detection of genetic robustness
EVOLUTION, 57(9), 1959–1972.
author keywords: canalization; environmental robustness; epistasis; evolvability; genetic robustness
TL;DR:
This work focuses on the first kind of robustness—genetic robustness)—and survey three growing avenues of research: measuring genetic robustness in nature and in the laboratory; understanding the evolution of genetic robusts; and exploring the implications of genetic resilientness for future evolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Pancreatic triacylglycerol lipase in a hibernating mammal. II. Cold-adapted function and differential expression
PHYSIOLOGICAL GENOMICS, 16(1), 131–140.
author keywords: lipolysis; low temperature; colipase; hibernation
MeSH headings : Adipose Tissue / enzymology; Adipose Tissue / metabolism; Animals; Blotting, Western; Cold Temperature; Colipases / genetics; DNA, Complementary / genetics; Gene Expression Profiling; Hibernation / genetics; Humans; Lipase / genetics; Lipase / metabolism; Male; Molecular Sequence Data; Myocardium / enzymology; Myocardium / metabolism; Organ Specificity; Pichia / genetics; RNA, Messenger / analysis; RNA, Messenger / genetics; RNA, Messenger / metabolism; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Sciuridae / genetics; Seasons; Testis / enzymology; Testis / metabolism
TL;DR:
The studies indicate that low-temperature lipolysis is a general property of PTL and does not require protein modifications unique to mammalian cells and/or the hibernating state.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Molecular characterization and functional analysis of the manganese-containing superoxide dismutase gene (sodA) from Streptococcus thermophilus AO54
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 420(1), 103–113.
author keywords: Streptococcus thermophilus; superoxide dismutase; MnSOD; sodA sequence; sodA mutant; SOD-null mutant; oxygen sensitivity; manganese ions; DNA polymerase III
MeSH headings : Amino Acid Sequence; Gene Expression Regulation, Enzymologic / drug effects; Magnesium Chloride / pharmacology; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Alignment; Sequence Analysis, Protein; Species Specificity; Streptococcus / chemistry; Streptococcus / drug effects; Streptococcus / enzymology; Streptococcus / genetics; Structure-Activity Relationship; Superoxide Dismutase / chemistry; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism
TL;DR:
The results suggest that sodA is essential for the aerobic growth of S. thermophilus and in the absence of functional SodA, manganese ions may provide partial protection against oxygen toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Genetic dissection of hybrid Incompatibilities between Drosophila simulansand D. mauritiana. II. Mapping hybrid male sterility loci on the third chromosome
Genetics, 164(4), 1399–1418.
Source: NC State University Libraries
Added: August 6, 2018
2003 journal article
Dopa decarboxylase (Ddc) affects variation in Drosophila longevity
NATURE GENETICS, 34(4), 429–433.
MeSH headings : Animals; Base Sequence; Chromosome Mapping; DNA / genetics; Dopa Decarboxylase / genetics; Drosophila melanogaster / enzymology; Drosophila melanogaster / genetics; Female; Genes, Insect; Genetic Complementation Test; Genetic Variation; Longevity / genetics; Male; Molecular Sequence Data; Mutation; Polymorphism, Genetic; Quantitative Trait Loci; Sequence Homology, Nucleic Acid; Species Specificity
TL;DR:
Variation in the synthesis of bioamines as a factor contributing to natural variation in individual life span is implicate by mapping quantitative trait loci affecting variation in longevity between two Drosophila melanogaster strains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 article
Development of a maize molecular evolutionary genomic database
Du, C. G., Buckler, E., & Muse, S. (2003, April). COMPARATIVE AND FUNCTIONAL GENOMICS, Vol. 4, pp. 246–249.
author keywords: database; maize; genome; evolution; germplasm; phenotype; SSR; DNA sequence
TL;DR:
PANZEA is the first public database for studying maize genomic diversity and has the ability to store, integrate and visualize DNA sequence, enzymatic, SSR (simple sequence repeat) marker, germplasm and phenotypic data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
The mode of evolution of molecular markers in populations of house mice under artificial selection for locomotor behavior
JOURNAL OF HEREDITY, 94(3), 236–242.
MeSH headings : Animals; Biological Evolution; Crosses, Genetic; Female; Gene Frequency; Genetic Markers; Genetic Variation; Genotype; Isoenzymes / genetics; Male; Mice; Mice, Inbred ICR; Microsatellite Repeats; Motor Activity / genetics
TL;DR:
The results generally provide support for the neutral evolution of molecular markers, and the pattern of change of allele frequencies between the base population and generation 14 was largely in agreement with expectations under neutral evolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Co-expression of a modified maize ribosome-inactivating protein and a rice basic chitinase gene in transgenic rice plants confers enhanced resistance to sheath blight
TRANSGENIC RESEARCH, 12(4), 475–484.
author keywords: antifungal; chitinase; co-expression; ribosome-inactivating protein; transgenic rice
MeSH headings : Blotting, Southern; Chitinases / genetics; Oryza / enzymology; Oryza / genetics; Oryza / microbiology; Plant Proteins / genetics; Plants, Genetically Modified / enzymology; Plants, Genetically Modified / genetics; Rhizoctonia / pathogenicity; Ribosome Inactivating Proteins
TL;DR:
The increased resistance co-segregated with herbicide tolerance, reflecting a correlation between the resistance phenotype and transgene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 review
Candidate genes, quantitative trait loci, and functional trait evolution in plants
[Review of ]. INTERNATIONAL JOURNAL OF PLANT SCIENCES, 164(3), S7–S20.
author keywords: QTL; flowering time; candidate gene; adaptive evolution; regulatory genes
TL;DR:
The insights into plant evolution that have been provided by molecular methods are reviewed and future research needs are addressed, indicating that plant growth variation may be directly regulated rather than primarily the indirect result of selection on constituent processes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Altered Cu metabolism and differential transcription of Cu/ZnSod genes in a Cu/ZnSOD-deficient mutant of maize: Evidence for a Cu-responsive transcription factor
BIOCHEMISTRY, 42(6), 1508–1516.
MeSH headings : Copper / metabolism; Copper / toxicity; Electron Transport Complex IV / metabolism; Enzyme Activation / drug effects; Genes, Plant; Isoenzymes / genetics; Isoenzymes / metabolism; Metallothionein / biosynthesis; Models, Biological; Paraquat / pharmacology; Plant Proteins / genetics; Plant Proteins / metabolism; Plant Proteins / physiology; Superoxide Dismutase / deficiency; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Transcription Factors / physiology; Transcription, Genetic / drug effects; Zea mays / drug effects; Zea mays / enzymology; Zea mays / genetics; Zinc / metabolism; Zinc / pharmacology
TL;DR:
High transcript levels of a constitutively expressed metallothionein, suggesting increased copper chelation capacity and creating a general copper-deprivation effect, seem to be a likely cause of the reduced levels of copper enzyme activity and Cu/ZnSod gene transcripts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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