Works Published in 2005
Displaying works 61 - 80 of 113 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2005 journal article
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C delta-mediated mechanism
AMERICAN JOURNAL OF PATHOLOGY, 167(3), 651–661.
MeSH headings : Bronchi / cytology; Bronchi / drug effects; Bronchi / metabolism; Cell Differentiation; Cells, Cultured; Enzyme Activation / drug effects; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Isoenzymes / metabolism; Leukocyte Elastase / pharmacology; Mucins / metabolism; Protein Kinase C / metabolism; Protein Kinase C / physiology; Protein Kinase C-delta; Protein Kinase Inhibitors / pharmacology
TL;DR:
The results suggest HNE stimulation of mucin release by human airway epithelial cells involves intracellular activation of PKC, specifically the delta isoform.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 review
Drug compounding for veterinary patients
[Review of ]. AAPS Journal, 7(2).
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Characterization of dried whey protein concentrate and isolate flavor
JOURNAL OF DAIRY SCIENCE, 88(11), 3826–3839.
author keywords: whey protein concentrate; whey protein isolate; flavor
MeSH headings : Alcohols / analysis; Aldehydes / analysis; Chromatography, Gas; Fatty Acids / analysis; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Ketones / analysis; Milk Proteins / chemistry; Milk Proteins / isolation & purification; Odorants / analysis; Smell; Taste; Vacuum; Volatilization; Water / analysis; Whey Proteins
TL;DR:
B baseline data on flavor and flavor sources in whey proteins will aid ongoing and future research and will help to identify the most appropriate whey ingredients to use to control or minimize flavor variability in Whey enhanced products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Astrocytes and microglia differentially regulate trafficking of lymphocyte subsets across brain endothelial cells
BRAIN RESEARCH, 1058(1-2), 148–160.
author keywords: HIV; FIV; CD4 T cell; CD8 T cell; B cell; monocyte
MeSH headings : Animals; Astrocytes / cytology; Astrocytes / physiology; B-Lymphocytes / cytology; B-Lymphocytes / immunology; Blood-Brain Barrier / cytology; Blood-Brain Barrier / immunology; Blood-Brain Barrier / virology; Brain / blood supply; Brain / immunology; Brain / virology; Cats; Cell Communication / immunology; Cells, Cultured; Cerebral Arteries / cytology; Cerebral Arteries / immunology; Cerebral Arteries / virology; Chemotaxis, Leukocyte / immunology; Coculture Techniques; Endothelial Cells / cytology; Endothelial Cells / physiology; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / physiopathology; Immune Tolerance / immunology; Immunodeficiency Virus, Feline / immunology; Lymphocytes / cytology; Lymphocytes / immunology; Microglia / cytology; Microglia / physiology; Monocytes / cytology; Monocytes / immunology; T-Lymphocytes / cytology; T-Lymphocytes / immunology
TL;DR:
Interaction between the triad of endothelial cells, astrocytes, and microglia played an important, but varying, role in the trafficking of different PBMC subsets, with astroCytes having a positive effect on trafficking of PBMCs, whilemicroglia had a suppressive effect.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Viability of glycerol-preserved and cryopreserved anuran skin
In Vitro Cellular & Developmental Biology. Animal, 41(09-Aug), 258–263.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Validation of a high-pressure liquid chromatography and fluorescence polarization immunoassay for the determination of methadone in canine plasma
THERAPEUTIC DRUG MONITORING, 27(3), 389–392.
author keywords: HPLC; FPIA; dog; concentration
MeSH headings : Animals; Chromatography, High Pressure Liquid / methods; Dogs; Female; Fluorescence Polarization Immunoassay / methods; Male; Methadone / blood
TL;DR:
FPIA provides a rapid, sensitive, and specific measurement of methadone in canine plasma following oral and intravenous administration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(5), 461–466.
MeSH headings : ATP Binding Cassette Transporter, Subfamily B, Member 1 / drug effects; Administration, Oral; Animals; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP3A / drug effects; Cytochrome P-450 CYP3A Inhibitors; Dogs / metabolism; Enzyme Inhibitors / administration & dosage; Enzyme Inhibitors / pharmacology; Female; Gastric Acid / metabolism; Injections, Intravenous / veterinary; Ketoconazole / administration & dosage; Ketoconazole / pharmacology; Male; Methadone / administration & dosage; Methadone / blood; Methadone / pharmacokinetics; Omeprazole / administration & dosage; Omeprazole / pharmacology; Proton Pump Inhibitors
TL;DR:
In contrast to its pharmacokinetics humans, methadone has a short elimination half-life, rapid clearance, and low oral bioavailability in dogs and the extent of absorption is not affected by inhibition of CYP3A, p-gp, and gastric acid secretion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Stringhalt associated with a pasture infested with Hypochoeris radicata
Equine Veterinary Education, 17(3), 118–122.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Pharmacokinetics of oral omeprazole in llamas
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(6), 539–543.
MeSH headings : Administration, Oral; Animals; Anti-Ulcer Agents / administration & dosage; Anti-Ulcer Agents / blood; Anti-Ulcer Agents / pharmacokinetics; Area Under Curve; Camelids, New World / metabolism; Female; Omeprazole / administration & dosage; Omeprazole / blood; Omeprazole / pharmacokinetics
TL;DR:
Oral omeprazole produced plasma drug concentrations which are not likely to be associated with clinical efficacy in camelids, and due to low absorption the oral dose was increased to 8 and 12 mg/kg and studies were repeated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Pharmacokinetics of florfenicol in the red pacu (Piaractus brachypomus) after single dose intramuscular administration
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(3), 317–319.
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Drug Administration Schedule; Fishes / metabolism; Injections, Intramuscular / veterinary; Thiamphenicol / administration & dosage; Thiamphenicol / analogs & derivatives; Thiamphenicol / blood; Thiamphenicol / pharmacokinetics
TL;DR:
The objectives of this study were to determine the maximum serum concentrations, elimination half-life, and relative bioavailability of florfenicol in the red pacu following single-dose intramuscular (i.m.) administration and reversephase high performance liquid chromatography (HPLC).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Pharmacokinetics and tissue fluid distribution of cephalexin in the horse after oral and i.v. administration
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(5), 425–431.
MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Cephalexin / administration & dosage; Cephalexin / blood; Cephalexin / pharmacokinetics; Cross-Over Studies; Female; Horses / metabolism; Injections, Intravenous / veterinary; Male; Tissue Distribution
TL;DR:
This study showed that cephalexin at a dose of 30 mg/kg administered orally at 8 h dosage intervals in horses can produce plasma and interstitial fluid drug concentrations that are in a range recommended to treat susceptible gram-positive bacteria (MIC < or = 0.5 microg/mL).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Enzymatic and microbiological inhibitory activity in eggshell membranes as influenced by layer strains and age and storage variables
POULTRY SCIENCE, 84(12), 1935–1941.
author keywords: eggshell membrane; beta-N-acetylglucosaminidase; lysozyme; stability; inhibitory activity
MeSH headings : Acetylglucosaminidase / metabolism; Aging / physiology; Animals; Chickens / classification; Chickens / genetics; Chickens / physiology; Egg Shell / chemistry; Egg Shell / cytology; Egg Shell / enzymology; Membranes / chemistry; Membranes / enzymology; Muramidase / metabolism; Specimen Handling; Temperature; Time Factors; Water
TL;DR:
It is demonstrated that ESM enzyme and biological activities are relatively constant across layer breeds and over extended storage and may have potential commercial value as a processing adjuvant in food and pharmaceutical product applications.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Enrofloxacin pharmacokinetics in the European cuttlefish, Sepia officinalis, after a single i.v. injection and bath administration
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 28(5), 433–439.
MeSH headings : Administration, Cutaneous; Administration, Oral; Animals; Area Under Curve; Bacteria / drug effects; Decapodiformes / metabolism; Decapodiformes / microbiology; Enrofloxacin; Fluoroquinolones / administration & dosage; Fluoroquinolones / blood; Fluoroquinolones / pharmacokinetics; Fluoroquinolones / pharmacology; Immersion; Injections, Intravenous / veterinary; Microbial Sensitivity Tests
TL;DR:
The hemolymph concentration was still above minimum inhibitory concentration values for shrimp and fish bacterial isolates at 6 h after i.v. administration, so a bath of 2.5 mg/L for 5 h once to twice daily is suggested for additional studies to test efficacy against highly susceptible organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Cloning and characterisation of genes encoding two transforming growth factor-beta-like ligands from the hookworm, Ancylostoma caninum
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 35(14), 1477–1487.
author keywords: Ancylostoma caninum; TGF-beta; dbl-1; daf-7; development
MeSH headings : Amino Acid Sequence; Ancylostoma / genetics; Animals; Base Sequence; Caenorhabditis elegans Proteins / genetics; Cloning, Molecular; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Larva; Molecular Sequence Data; Receptors, Transforming Growth Factor beta / analysis; Receptors, Transforming Growth Factor beta / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology
TL;DR:
Immunofluorescent studies showed that Ac-daf-7 is expressed in the anterior region of the iL3 similar to Ce-dft-7, which is localised to the ASI chemosensory neurons, which may be unique to parasitic nematodes that have an obligate requirement to undergo developmental arrest.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Use of radiography in combination with computed tomography for the assessment of noncardiac thoracic disease in the dog and cat
VETERINARY RADIOLOGY & ULTRASOUND, 46(2), 114–121.
author keywords: computed tomography; thoracic diseases; thoracic radiographs
MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cats; Dog Diseases / diagnostic imaging; Dogs; Female; Male; Predictive Value of Tests; Radiography, Thoracic / veterinary; Thoracic Diseases / diagnostic imaging; Thoracic Diseases / veterinary; Tomography, X-Ray Computed / veterinary
TL;DR:
Computed tomography is a valuable tool for evaluating intrathoracic disease because it provides additional cross-sectional anatomic information that can aid in anatomic localization and evaluation of the extent of the pathology in question.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Sonic hedgehog is required for cardiac outflow tract and neural crest cell development
DEVELOPMENTAL BIOLOGY, 283(2), 357–372.
author keywords: cardiac; neural crest; migration; pulmonary atresia; tetralogy of Fallot; outflow tract; septation; anterior heart field; Bmp4; repulsion
MeSH headings : Animals; Arteries / embryology; Body Patterning; Branchial Region / embryology; Cell Death; Cell Proliferation; Endoderm / physiology; Female; Heart / embryology; Hedgehog Proteins; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins / biosynthesis; Mice; Mice, Knockout; Neural Crest / cytology; Neural Crest / embryology; Neural Crest / metabolism; Patched Receptors; Receptors, Cell Surface; Signal Transduction; Trans-Activators / genetics
TL;DR:
This study focuses on the defects in pharyngeal arch and cardiovascular patterning present in Sonic hedgehog (Shh) null mouse embryos and suggests that SHH signaling acts to restrict the domains that NCCs can populate during early stages (e8.5-10.5) of cardiovascular and craniofacial development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Preferential and non-selective cyclooxygenase inhibitors reduce inflammation during lipopolysaccharide-induced synovitis
RESEARCH IN VETERINARY SCIENCE, 78(2), 189–192.
author keywords: prostaglandin; synovitis; etodolac; phenylbutazone; thromboxane
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Cyclooxygenase Inhibitors / pharmacology; Dinoprostone / analysis; Enzyme-Linked Immunosorbent Assay / veterinary; Etodolac / pharmacology; Horse Diseases / drug therapy; Horse Diseases / enzymology; Horse Diseases / pathology; Horses; Leukocyte Count / veterinary; Lipopolysaccharides; Phenylbutazone / pharmacology; Random Allocation; Synovial Fluid / chemistry; Synovitis / drug therapy; Synovitis / enzymology; Synovitis / pathology; Synovitis / veterinary; T-Box Domain Proteins / analysis
TL;DR:
Etodolac may serve as a more selective anti-inflammatory agent than phenylbutazone for treatment of equine synovitis, as compared to non-selective COX inhibitors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Pre-existing immunity to pathogenic Listeria monocytogenes does not prevent induction of immune responses to feline immunodeficiency virus by a novel recombinant Listeria monocytogenes vaccine
VACCINE, 23(12), 1479–1490.
author keywords: Listeria monocytogenes; feline immunodeficiency virus; HIV
MeSH headings : Animals; Antibodies, Viral / analysis; Antigens, Viral / genetics; Antigens, Viral / immunology; Cats; Disease Models, Animal; Feces; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / prevention & control; Female; Gene Products, env / genetics; Gene Products, env / immunology; Gene Products, gag / genetics; Gene Products, gag / immunology; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / immunology; Immunoglobulin A / analysis; Listeria monocytogenes / genetics; Listeria monocytogenes / immunology; Saliva / immunology; Vaccines, Synthetic / administration & dosage; Vaccines, Synthetic / immunology; Vagina / immunology; Viral Proteins / genetics; Viral Proteins / immunology; Viral Vaccines / administration & dosage; Viral Vaccines / immunology
TL;DR:
Using a simplified approach to introduce individual and polyprotein FIV gag genes, it is shown that recombinant L. monocytogenes containing the entire gag expresses the full-length Gag polyprotein in a soluble secreted form.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Pharmacokinetics after intravenous, subcutaneous, and oral administration of enrofloxacin to alpacas
American Journal of Veterinary Research, 66(5), 767–771.
MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Camelids, New World / metabolism; Enrofloxacin; Female; Fluoroquinolones / administration & dosage; Fluoroquinolones / blood; Fluoroquinolones / pharmacokinetics; Half-Life; Injections, Intravenous / veterinary; Injections, Subcutaneous / veterinary; Quinolones / administration & dosage; Quinolones / blood; Quinolones / pharmacokinetics
TL;DR:
The administration of enrofloxacin (5 mg/kg, s.c. and p.o) may be appropriate for antimicrobial treatment of alpacas and yielded a ratio for AUC to minimum inhibitory concentration > 100 for many grampositive and gram-negative bacterial pathogens common to camelids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2005 journal article
Molecular characterization of trichomonads from feces of dogs with diarrhea
JOURNAL OF PARASITOLOGY, 91(4), 939–943.
MeSH headings : Animals; Base Sequence; DNA, Protozoan / chemistry; DNA, Protozoan / isolation & purification; Diarrhea / parasitology; Diarrhea / veterinary; Dog Diseases / parasitology; Dogs; Electrophoresis, Agar Gel / veterinary; Feces / parasitology; Female; Molecular Sequence Data; Polymerase Chain Reaction / veterinary; Protozoan Infections / parasitology; Protozoan Infections, Animal; RNA, Ribosomal / genetics; Sequence Alignment / veterinary; Trichomonadida / classification; Trichomonadida / genetics; Trichomonadida / isolation & purification; Tritrichomonas foetus / classification; Tritrichomonas foetus / genetics; Tritrichomonas foetus / isolation & purification
TL;DR:
The present study is the first to establish the molecular identity of trichomonads infecting dogs with diarrhea, and validate the longstanding assumption that canine trICHomoniasis may be attributed to P. hominis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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