Works Published in 2015
Displaying works 61 - 80 of 134 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Detection of BRAF Mutation in Urine DNA as a Molecular Diagnostic for Canine Urothelial and Prostatic Carcinoma
PLOS ONE, 10(12).
Contributors: H. Mochizuki n , S. Shapiro n & M. Breen n
MeSH headings : Animals; Biomarkers, Tumor / urine; DNA / urine; Dogs; Male; Mutation; Polymerase Chain Reaction; Prostatic Neoplasms / diagnosis; Prostatic Neoplasms / urine; Proto-Oncogene Proteins B-raf / genetics; Urinary Bladder Neoplasms / diagnosis; Urinary Bladder Neoplasms / urine
TL;DR:
It is shown that ddPCR is a sensitive molecular technique with the potential to facilitate accurate and non-invasive means of canine UC and PC diagnosis.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Understanding companion animal practitioners' attitudes toward antimicrobial stewardship
Journal of the American Veterinary Medical Association, 247(8), 883–884.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips
PLOS ONE, 10(11).
MeSH headings : Animals; Coronary Vessels / surgery; Disease Models, Animal; Ligation; Mice; Myocardial Infarction / etiology; Myocardial Infarction / mortality; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Surgical Instruments; Suture Techniques; Vascular Surgical Procedures
TL;DR:
This new method, taking only less than 3 minutes to complete, represents an efficient myocardial infarction model in rodents and improved post-MI survival rate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Phenotypic and functional analysis of CD1a+dendritic cells from cats chronically infected with feline immunodeficiency virus
Comparative Immunology, Microbiology and Infectious Diseases, 42, 53–59.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 247(8), 938–944.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cross-Sectional Studies; Data Collection; Drug Resistance, Bacterial; Education, Veterinary; Female; Hospitals, Animal; Humans; Male; Professional Practice; Schools, Veterinary; United States; Veterinarians
TL;DR:
Findings indicated that veterinarians at this teaching hospital were concerned about antimicrobial resistance, thought antimicrobials were overprescribed, and supported restricting use of certain antimicrobial classes in companion animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice
ENVIRONMENTAL HEALTH PERSPECTIVES, 123(8), 799–805.
MeSH headings : Air Pollutants / toxicity; Animals; Bronchoalveolar Lavage Fluid; Disease Susceptibility / immunology; Gene Expression / drug effects; Gene Expression Regulation / drug effects; Male; Mice; Mice, Knockout; Ozone / toxicity; Pneumonia / chemically induced; Proto-Oncogene Proteins / genetics; Proto-Oncogene Proteins / metabolism; Receptor, Notch3; Receptor, Notch4; Receptors, Notch / genetics; Receptors, Notch / metabolism
TL;DR:
Novel roles for Notch3 and Notch4 receptors in gene expression and susceptibility to ozone-induced lung inflammation in mice are suggested, and suggest that Notch receptors protect against innate immune inflammation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Mucosal Immunogenicity of Genetically Modified Lactobacillus acidophilus Expressing an HIV-1 Epitope within the Surface Layer Protein
PLOS ONE, 10(10).
MeSH headings : Adaptive Immunity; Animals; Antibodies, Bacterial / immunology; Antibody Formation / immunology; Antibody Specificity / immunology; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Cytokines / metabolism; Epitopes / genetics; Epitopes / immunology; HIV-1 / genetics; HIV-1 / immunology; Humans; Immunity, Mucosal; Immunization; Immunoglobulin A / immunology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / immunology; Mice; Models, Animal; Mucous Membrane / immunology; Mucous Membrane / microbiology; Mucous Membrane / virology; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / immunology
TL;DR:
The constructed genetically modified Lactobacillus acidophilus strains expressing the membrane proximal external region (MPER) from human immunodeficiency virus type 1 (HIV-1) within the context of the major S-layer protein, SlpA, demonstrated the potential use of the LactOBacillus S- layer protein for development of oral vaccines targeting specific peptides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Isolation and Cryopreservation of Neonatal Rat Cardiomyocytes
Journal of Visualized Experiments, (98).
author keywords: Developmental Biology; Issue 98; Cryopreservation; Cardiomyocytes; Cell-based Assay; Cell Culture; Cardiac Research; In Vitro Assay
MeSH headings : Actinin / analysis; Actinin / metabolism; Animals; Animals, Newborn; Cell Culture Techniques; Cell Separation / methods; Cell Survival / physiology; Cryopreservation / methods; Cryoprotective Agents / chemistry; Dimethyl Sulfoxide / chemistry; Freezing; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats; Sarcomeres / chemistry; Sarcomeres / metabolism
TL;DR:
Cryopreservation methods allow one to easily cryopreserve and thaw neonatal rat cardiomyocytes, which gives researchers a greater amount of flexibility in planning experiments as well as reducing the use of animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Excess Secretion of Gel-Forming Mucins and Associated Innate Defense Proteins with Defective Mucin Un-Packaging Underpin Gallbladder Mucocele Formation in Dogs
PLOS ONE, 10(9).
MeSH headings : Animals; Dogs; Epithelial Cells / pathology; Epithelial Cells / ultrastructure; Epithelium / pathology; Exocytosis; Gallbladder / diagnostic imaging; Gallbladder / pathology; Gallbladder / surgery; Gallbladder / ultrastructure; Gels / metabolism; Glycosylation; Immunity, Innate; Immunoblotting; Male; Mass Spectrometry; Mucin 5AC / metabolism; Mucin-5B / metabolism; Mucocele / diagnostic imaging; Mucocele / pathology; Mucocele / surgery; Mucous Membrane / pathology; Mucus / metabolism; Phenotype; Rupture; Ultrasonography
TL;DR:
These findings provide an explanation for abnormal mucus behavior and based on similarity to mucus observed in the airways of people with cystic fibrosis, suggest that abnormal mechanisms for maintenance of gallbladder epithelial hydration may be an instigating factor for mucocele formation in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Aggression behaviour induced by oral administration of the Janus-kinase inhibitor tofacitinib, but not oclacitinib, under stressful conditions
European Journal of Pharmacology, 764, 278–282.
MeSH headings : Administration, Oral; Aggression / drug effects; Animals; Anti-Allergic Agents / adverse effects; Anti-Allergic Agents / pharmacokinetics; Anti-Allergic Agents / therapeutic use; Anti-Inflammatory Agents / adverse effects; Anti-Inflammatory Agents / pharmacokinetics; Anti-Inflammatory Agents / therapeutic use; Behavior, Animal / drug effects; Brain / metabolism; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / metabolism; Disease Models, Animal; Female; Janus Kinases / antagonists & inhibitors; Janus Kinases / metabolism; Male; Mice, Inbred BALB C; Piperidines / adverse effects; Piperidines / pharmacokinetics; Piperidines / therapeutic use; Protein Kinase Inhibitors / adverse effects; Protein Kinase Inhibitors / pharmacokinetics; Protein Kinase Inhibitors / therapeutic use; Pruritus / chemically induced; Pruritus / drug therapy; Pruritus / metabolism; Pyrimidines / adverse effects; Pyrimidines / pharmacokinetics; Pyrimidines / therapeutic use; Pyrroles / adverse effects; Pyrroles / pharmacokinetics; Pyrroles / therapeutic use; Stress, Psychological; Sulfonamides / pharmacokinetics; Sulfonamides / therapeutic use; Toluene 2,4-Diisocyanate
TL;DR:
Results suggest that aggression was induced by tofacitinib under some kind of stressful environment, and indicates a possible role of the JAK-STAT pathway in modulation of aggression behaviour.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Transplantation of GABAergic Interneurons into the Neonatal Primary Visual Cortex Reduces Absence Seizures in Stargazer Mice
CEREBRAL CORTEX, 25(9), 2970–2979.
author keywords: absence seizure; MGE transplantation; network activity; Stargazer; visual cortex
MeSH headings : Animals; Calcium Channels / genetics; Calcium Channels / metabolism; Disease Models, Animal; Embryo, Mammalian; Epilepsy, Absence / genetics; Epilepsy, Absence / surgery; GABAergic Neurons / physiology; GABAergic Neurons / transplantation; Glutamate Decarboxylase / metabolism; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; In Vitro Techniques; Median Eminence / cytology; Membrane Potentials / drug effects; Membrane Potentials / physiology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex / cytology; Nerve Tissue Proteins / metabolism; Proto-Oncogene Proteins c-fos / metabolism; Treatment Outcome; Visual Cortex / transplantation; gamma-Aminobutyric Acid / metabolism
TL;DR:
It is reported that transplantation of MGE cells into the primary visual cortex (V1) of Stg mice significantly reduces AE episodes and lowers mortality and presents MGE grafting in the V1 as a possible clinical approach in the treatment of AE.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Plasma concentrations of lidocaine in dogs following lidocaine patch application over an incision compared to intact skin
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 38(6), 575–580.
MeSH headings : Anesthetics, Local / administration & dosage; Anesthetics, Local / blood; Anesthetics, Local / pharmacokinetics; Animals; Dogs / blood; Dogs / surgery; Female; Lidocaine / administration & dosage; Lidocaine / blood; Lidocaine / pharmacokinetics; Male; Skin / metabolism; Transdermal Patch
TL;DR:
It is demonstrated that the actual body exposure to lidocaine was significantly higher when an incision was present compared to intact skin, and the AUC was significantlyHigher in the Incision Group.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Olfactory discrimination and generalization of ammonium nitrate and structurally related odorants in Labrador retrievers
Animal Cognition, 18(6), 1255–1265.
MeSH headings : Aluminum; Ammonium Compounds; Animals; Discrimination Learning; Discrimination, Psychological; Dogs; Explosive Agents; Fertilizers; Iraq; Nitrates; Odorants; Smell / physiology; Soil
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging
AGING CELL, 14(5), 764–773.
author keywords: aging; barrier function; Clca3; cerebral cortex; ependymal cells; lipid droplets; mucin; oxidative stress
MeSH headings : Aging / metabolism; Animals; Ependyma / cytology; Ependyma / metabolism; Homeostasis; Intracellular Signaling Peptides and Proteins / deficiency; Intracellular Signaling Peptides and Proteins / metabolism; Lipid Metabolism; Membrane Proteins / deficiency; Membrane Proteins / metabolism; Mice; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Oxidative Stress; Prosencephalon / metabolism
TL;DR:
It is demonstrated that metabolic and barrier functions in ECs decline significantly during aging in mice, and this work constitutes a conceptually new paradigm in the potential role of ECs in the initiation of various conditions and diseases in the aging brain.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Generating primary cultures of murine cardiac myocytes and cardiac fibroblasts to study viral myocarditis
Cardiomyocytes: Methods and Protocols, 1299, 1–16.
Source: NC State University Libraries
Added: August 6, 2018
2015 chapter
Cryopreservation of Neonatal Cardiomyocytes
In Methods in Molecular Biology (Vol. 1299, pp. 153–160).
author keywords: Cardiomyocytes; Cryopreservation; Cardiac research
MeSH headings : Animals; Animals, Newborn; Cell Culture Techniques; Cells, Cultured; Cryopreservation / methods; Myocytes, Cardiac / cytology; Rats
TL;DR:
A method for cryopreserving neonatal rat cardiomyocytes (NRCMs), and subsequently thawing them for use in assays and to reduce the time requirements and the impact on research animals is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
COMPUTED TOMOGRAPHIC AND ULTRASONOGRAPHIC CHARACTERISTICS OF CAVERNOUS TRANSFORMATION OF THE OBSTRUCTED PORTAL VEIN IN SMALL ANIMALS
VETERINARY RADIOLOGY & ULTRASOUND, 56(5), 511–519.
author keywords: Cavernous transformation; CT-angiography; obstruction; portal collaterals; portal vein
MeSH headings : Angiography / veterinary; Animals; Cat Diseases / diagnostic imaging; Cats; Collateral Circulation; Cross-Sectional Studies; Dog Diseases / diagnostic imaging; Dogs; Female; Hypertension, Portal / diagnostic imaging; Hypertension, Portal / veterinary; Male; Multidetector Computed Tomography / veterinary; Portal Vein / abnormalities; Portal Vein / diagnostic imaging; Retrospective Studies
TL;DR:
Describing MDCT and ultrasonographic characteristics of presumed cavernous transformation of the portal vein in small animals with portal vein obstruction using ultrasound and multidetector-row computed tomography (MDCT) was provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Bispecific antibodies, nanoparticles and cells: Bringing the right cells to get the job done
Expert Opinion on Biological Therapy, 15(9), 1251–1255.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis
STEM CELLS TRANSLATIONAL MEDICINE, 4(11), 1265–1274.
author keywords: Adult lung stem cells; Mesenchymal stem cells; Pulmonary fibrosis; Spheroid cell culture
MeSH headings : Adult; Animals; Antibiotics, Antineoplastic / adverse effects; Antibiotics, Antineoplastic / pharmacology; Bleomycin / adverse effects; Bleomycin / pharmacology; Female; Heterografts; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Mice; Mice, SCID; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / therapy; Regeneration; Spheroids, Cellular / metabolism; Spheroids, Cellular / transplantation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Vaccination of calves with yeast- and bacterial-expressed paramyosin from the bovine lungworm Dictyocaulus viviparus
PARASITE IMMUNOLOGY, 37(12), 614–623.
author keywords: bovine lungworm; Dictyocaulus viviparus; immunization; nematode; paramyosin; vaccine
MeSH headings : Animals; Antibodies, Helminth / immunology; Antigens, Helminth / genetics; Antigens, Helminth / immunology; Cattle; Cattle Diseases / prevention & control; Dictyocaulus / immunology; Dictyocaulus Infections / prevention & control; Escherichia coli / genetics; Escherichia coli / metabolism; Female; Helminth Proteins / genetics; Helminth Proteins / immunology; Immunoglobulin G / immunology; Larva; Leukocytes, Mononuclear / immunology; Male; Recombinant Proteins; Tropomyosin / genetics; Tropomyosin / immunology; Vaccination / veterinary; Vaccines / immunology; Yeasts / genetics; Yeasts / metabolism
TL;DR:
All vaccinated cattle showed a significant rise in specific antibodies, particularly IgG and its subclass IgG1, and detected the native lungworm PMY in immunoblots starting 2 weeks after the first vaccination, suggesting a different rPMY‐adjuvant combination or combined vaccination with additional recombinant antigens might be a promising future approach towards a new vaccine against lungworms in cattle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
